magnesium citrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4281 3344-18-1

Description:

MoleculeDescription

Synonyms:

  • magnesium citrate
  • citric acid magnesium salt
  • trimagnesium dicitrate
  • Molecular weight: 451.11
  • Formula: C12H10Mg3O14
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 140.62
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
2 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Blepharospasm 194.61 10.45 239 77518 55206 90495484
Onychomadesis 185.75 10.45 213 77544 45785 90504905
Onychomycosis 178.49 10.45 189 77568 37187 90513503
Taste disorder 164.40 10.45 232 77525 61314 90489376
Gastrooesophageal reflux disease 140.17 10.45 385 77372 165952 90384738
Toxicity to various agents 136.26 10.45 39 77718 287807 90262883
Product quality issue 121.98 10.45 233 77524 79092 90471598
Epilepsy 118.54 10.45 235 77522 81971 90468719
Muscle spasms 115.62 10.45 475 77282 251408 90299282
Injection site reaction 111.47 10.45 245 77512 91835 90458855
Memory impairment 100.99 10.45 385 77372 196859 90353831
Back injury 100.51 10.45 159 77598 46463 90504227
Breast cancer stage III 89.27 10.45 213 77544 84234 90466456
Nail disorder 87.74 10.45 171 77586 58896 90491794
Drug ineffective 84.26 10.45 772 76985 1383526 89167164
Peripheral venous disease 77.46 10.45 201 77556 83720 90466970
Migraine 76.50 10.45 345 77412 190047 90360643
Facet joint syndrome 76.23 10.45 221 77536 98168 90452522
Depression 69.66 10.45 469 77288 300132 90250558
Dry mouth 69.12 10.45 327 77430 183732 90366958
Intentional overdose 67.68 10.45 3 77754 93831 90456859
Hypocholesterolaemia 63.42 10.45 49 77708 6400 90544290
Drug interaction 60.12 10.45 90 77667 276363 90274327
Finger deformity 57.31 10.45 102 77655 32795 90517895
Off label use 56.42 10.45 640 77117 1101612 89449078
Psoriatic arthropathy 54.52 10.45 359 77398 227976 90322714
Grip strength decreased 53.48 10.45 188 77569 92388 90458302
Adverse reaction 52.89 10.45 93 77664 29619 90521071
Product label confusion 52.13 10.45 80 77677 22770 90527920
Sleep disorder due to general medical condition, insomnia type 49.84 10.45 24 77733 128670 90422020
Hypercholesterolaemia 49.19 10.45 194 77563 100698 90449992
Liver function test increased 48.74 10.45 172 77585 84683 90466007
Lip dry 48.32 10.45 193 77564 100762 90449928
Abdominal distension 48.26 10.45 231 77526 130370 90420320
COVID-19 47.32 10.45 45 77712 168798 90381892
Night sweats 47.04 10.45 227 77530 128539 90422151
Asthenia 45.52 10.45 676 77081 533075 90017615
C-reactive protein increased 43.78 10.45 286 77471 181103 90369587
Paraesthesia 42.42 10.45 363 77394 249963 90300727
Neck pain 42.41 10.45 202 77555 113761 90436929
Bursitis 41.03 10.45 222 77535 131432 90419258
Sleep disorder 40.58 10.45 300 77457 197730 90352960
Hypoaesthesia 40.52 10.45 430 77327 313780 90236910
Suicide attempt 39.99 10.45 8 77749 75391 90475299
Joint range of motion decreased 39.79 10.45 225 77532 135418 90415272
Infusion site reaction 39.75 10.45 64 77693 18975 90531715
Live birth 39.28 10.45 153 77604 78954 90471736
Rheumatic fever 38.52 10.45 244 77513 152877 90397813
Unevaluable event 37.57 10.45 118 77639 54730 90495960
Diarrhoea 37.14 10.45 1061 76696 938129 89612561
Congenital anomaly 35.57 10.45 35 77722 6312 90544378
Wound infection 34.23 10.45 181 77576 106221 90444469
Fall 33.84 10.45 591 77166 481219 90069471
Full blood count decreased 32.57 10.45 76 77681 29613 90521077
Pyrexia 32.30 10.45 387 77370 660098 89890592
Dizziness 31.96 10.45 695 77062 588589 89962101
Device expulsion 31.81 10.45 92 77665 40794 90509896
Asthma 30.50 10.45 106 77651 242054 90308636
Blood cholesterol increased 30.32 10.45 292 77465 207720 90342970
Obesity 30.27 10.45 174 77583 105333 90445357
Acute kidney injury 29.48 10.45 158 77599 320229 90230461
Gait inability 28.37 10.45 219 77538 146237 90404453
Obstructive defaecation 27.88 10.45 10 77747 260 90550430
Coeliac disease 27.86 10.45 93 77664 44517 90506173
Visual snow syndrome 27.80 10.45 7 77750 50 90550640
Product dose omission issue 27.43 10.45 376 77381 291311 90259379
Stoma site dermatitis 27.32 10.45 10 77747 276 90550414
Infection 26.85 10.45 191 77566 361903 90188787
Inflammation 26.17 10.45 251 77506 178341 90372349
Lung disorder 25.71 10.45 218 77539 149665 90401025
Therapy cessation 25.61 10.45 79 77678 36282 90514408
Drug tolerance 25.55 10.45 51 77706 17865 90532825
Febrile neutropenia 25.26 10.45 62 77695 158287 90392403
Injury 24.91 10.45 269 77488 197080 90353610
Drug intolerance 24.31 10.45 256 77501 447335 90103355
Adverse drug reaction 24.00 10.45 177 77580 116524 90434166
Thrombocytopenia 23.90 10.45 95 77662 208630 90342060
Gastrointestinal stoma output abnormal 23.59 10.45 10 77747 410 90550280
Pruritus 23.59 10.45 325 77432 541200 90009490
Type 2 diabetes mellitus 23.36 10.45 272 77485 202972 90347718
Dyspepsia 23.14 10.45 266 77491 197894 90352796
Flatulence 23.02 10.45 83 77674 41284 90509406
Device dislocation 22.74 10.45 69 77688 31413 90519277
Hepatic function abnormal 22.38 10.45 6 77751 46282 90504408
C-reactive protein abnormal 21.67 10.45 185 77572 127244 90423446
Anaphylactic reaction 21.53 10.45 26 77731 87498 90463192
Abdominal pain upper 21.53 10.45 403 77354 332271 90218419
Underdose 21.01 10.45 97 77660 53920 90496770
Illness 20.54 10.45 24 77733 81945 90468745
Muscular weakness 20.07 10.45 268 77489 206398 90344292
Foetal exposure during pregnancy 19.98 10.45 6 77751 42969 90507721
Multiple organ dysfunction syndrome 19.39 10.45 18 77739 68318 90482372
Musculoskeletal pain 19.15 10.45 228 77529 171023 90379667
Cholestasis 18.94 10.45 4 77753 36295 90514395
Premature delivery 18.79 10.45 5 77752 38757 90511933
Gait disturbance 18.77 10.45 321 77436 260175 90290515
Intentional product misuse 18.66 10.45 30 77727 89574 90461116
Liver injury 18.60 10.45 226 77531 170341 90380349
Interstitial lung disease 18.48 10.45 23 77734 76382 90474308
Cardiac arrest 18.42 10.45 39 77718 104896 90445794
Deep vein thrombosis 18.30 10.45 138 77619 91482 90459208
Drug eruption 18.27 10.45 4 77753 35403 90515287
Insomnia 18.25 10.45 394 77363 333080 90217610
Drug reaction with eosinophilia and systemic symptoms 18.10 10.45 7 77750 42751 90507939
Agranulocytosis 17.97 10.45 4 77753 34998 90515692
Hepatitis 17.95 10.45 113 77644 70626 90480064
Stoma site inflammation 17.78 10.45 10 77747 764 90549926
Lactic acidosis 17.23 10.45 11 77746 50452 90500238
Plasma cell myeloma 17.14 10.45 75 77682 40753 90509937
Laboratory test abnormal 16.90 10.45 76 77681 41778 90508912
Ill-defined disorder 16.82 10.45 237 77520 184654 90366036
Stoma site pain 16.69 10.45 12 77745 1405 90549285
Ulcer haemorrhage 16.55 10.45 55 77702 26266 90524424
Erythema 16.46 10.45 122 77635 229124 90321566
Blood pressure systolic increased 15.82 10.45 16 77741 58329 90492361
Intentional self-injury 15.79 10.45 3 77754 29331 90521359
Normal newborn 15.75 10.45 50 77707 23312 90527378
Osteonecrosis of jaw 15.58 10.45 7 77750 39096 90511594
Altered state of consciousness 15.41 10.45 4 77753 31528 90519162
Dislocation of vertebra 15.20 10.45 91 77666 55877 90494813
Eosinophilia 15.19 10.45 3 77754 28530 90522160
Fibromyalgia 15.16 10.45 255 77502 206014 90344676
Feeling abnormal 15.06 10.45 214 77543 167021 90383669
Neutropenia 15.06 10.45 122 77635 224782 90325908
Neuropathy peripheral 14.72 10.45 181 77576 136789 90413901
Coma 14.49 10.45 25 77732 72607 90478083
Metabolic acidosis 14.28 10.45 16 77741 55660 90495030
Leukopenia 14.12 10.45 42 77715 100668 90450022
Discomfort 14.04 10.45 159 77598 274176 90276514
Hot flush 13.85 10.45 93 77664 59395 90491295
Depressed level of consciousness 13.67 10.45 26 77731 72758 90477932
Arthritis 13.51 10.45 86 77671 167229 90383461
Blood pressure fluctuation 13.51 10.45 15 77742 52398 90498292
Shock 13.41 10.45 4 77753 28774 90521916
Gamma-glutamyltransferase increased 13.34 10.45 8 77749 37944 90512746
Serotonin syndrome 13.29 10.45 8 77749 37879 90512811
Mucosal inflammation 13.26 10.45 18 77739 57607 90493083
Angioedema 13.25 10.45 22 77735 64854 90485836
Hepatotoxicity 13.09 10.45 12 77745 45830 90504860
Faeces hard 13.06 10.45 15 77742 3227 90547463
Osteoarthritis 12.96 10.45 238 77519 195492 90355198
Gastrointestinal stoma complication 12.93 10.45 13 77744 2406 90548284
Therapeutic response decreased 12.89 10.45 37 77720 89692 90460998
Rhabdomyolysis 12.85 10.45 15 77742 51241 90499449
Prostatic specific antigen abnormal 12.69 10.45 4 77753 69 90550621
Respiratory sinus arrhythmia magnitude 12.69 10.45 4 77753 69 90550621
Premature baby 12.61 10.45 3 77754 25074 90525616
Hepatic enzyme 12.60 10.45 19 77738 5325 90545365
Underweight 12.46 10.45 10 77747 1380 90549310
Cardiac failure 12.42 10.45 50 77707 109446 90441244
Hyperkalaemia 12.39 10.45 23 77734 64941 90485749
Pelvic pain 12.37 10.45 35 77722 15322 90535368
Rhonchi 12.37 10.45 14 77743 2964 90547726
Cardio-respiratory arrest 12.35 10.45 22 77735 63118 90487572
Accidental exposure to product 12.21 10.45 11 77746 42355 90508335
Hiccups 12.19 10.45 14 77743 3012 90547678
Blood pressure diastolic decreased 12.02 10.45 4 77753 26822 90523868
Condition aggravated 11.91 10.45 405 77352 595140 89955550
Focal segmental glomerulosclerosis 11.88 10.45 11 77746 1840 90548850
Hepatic failure 11.83 10.45 10 77747 39718 90510972
Respiratory arrest 11.74 10.45 7 77750 33304 90517386
Bradycardia 11.73 10.45 35 77722 83812 90466878
Hyponatraemia 11.64 10.45 67 77690 133471 90417219
Drug ineffective for unapproved indication 11.50 10.45 25 77732 66619 90484071
Blood lactate dehydrogenase increased 11.39 10.45 4 77753 25928 90524762
Skin ulcer 11.16 10.45 16 77741 50059 90500631
Cytokine release syndrome 11.16 10.45 5 77752 27968 90522722
Nausea 11.14 10.45 1101 76656 1109215 89441475
Metastases to bone 11.09 10.45 4 77753 25501 90525189
Blood pressure increased 11.01 10.45 112 77645 197105 90353585
Malignant neoplasm progression 10.79 10.45 51 77706 106819 90443871
Macular degeneration 10.77 10.45 10 77747 37960 90512730
Product use issue 10.70 10.45 209 77548 329710 90220980
Foot deformity 10.61 10.45 22 77735 59629 90491061
Dermatitis exfoliative generalised 10.60 10.45 18 77739 5575 90545115
Headache 10.55 10.45 868 76889 861878 89688812
Hip arthroplasty 10.53 10.45 32 77725 76176 90474514
Tetany 10.48 10.45 12 77745 2572 90548118
Immunodeficiency 10.47 10.45 13 77744 43221 90507469

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Off label use 118.32 12.10 132 26110 638203 41956890
Fatigue 80.02 12.10 499 25743 435142 42159951
Product use in unapproved indication 79.48 12.10 10 26232 184446 42410647
Plasma cell myeloma 55.91 12.10 103 26139 47475 42547618
Product dose omission issue 46.32 12.10 203 26039 154162 42440931
Asthenia 44.27 12.10 310 25932 280483 42314610
Diarrhoea 43.22 12.10 453 25789 460396 42134697
Fall 42.43 12.10 268 25974 234252 42360841
Completed suicide 42.08 12.10 5 26237 96460 42498633
Drug interaction 39.27 12.10 65 26177 266934 42328159
Full blood count decreased 38.49 12.10 55 26187 20505 42574588
Constipation 37.51 12.10 198 26044 162093 42433000
Laboratory test abnormal 36.61 12.10 57 26185 22921 42572172
White blood cell count decreased 33.71 12.10 146 26096 110250 42484843
Drug ineffective 29.84 12.10 247 25995 629950 41965143
Toxicity to various agents 29.06 12.10 61 26181 229075 42366018
Pneumonia 28.50 12.10 390 25852 421759 42173334
Dizziness 27.13 12.10 253 25989 249001 42346092
Adverse drug reaction 26.52 12.10 66 26176 37368 42557725
Muscle spasms 26.41 12.10 114 26128 85930 42509163
Neuropathy peripheral 26.12 12.10 128 26114 101725 42493368
Viral infection 25.55 12.10 48 26194 22435 42572658
General physical health deterioration 22.97 12.10 36 26206 151210 42443883
Peripheral swelling 22.12 12.10 112 26130 90158 42504935
Treatment failure 21.42 12.10 6 26236 62618 42532475
Psoriasis 20.30 12.10 71 26171 48533 42546560
Sinusitis 19.68 12.10 69 26173 47223 42547870
Intentional product use issue 19.38 12.10 10 26232 71823 42523270
Influenza 18.03 12.10 81 26161 62094 42532999
Feeling abnormal 17.38 12.10 87 26155 69699 42525394
Rash 17.07 12.10 252 25990 276702 42318391
Interstitial lung disease 16.99 12.10 14 26228 78448 42516645
Multiple organ dysfunction syndrome 16.82 12.10 21 26221 97014 42498079
Flatulence 16.42 12.10 43 26199 25109 42569984
COVID-19 16.30 12.10 29 26213 115919 42479174
Dehydration 15.94 12.10 145 26097 141622 42453471
Cardiac disorder 15.91 12.10 66 26176 48866 42546227
Intentional overdose 15.71 12.10 6 26236 51450 42543643
Hypervolaemia 15.57 12.10 40 26202 23085 42572008
Coma 15.14 12.10 7 26235 53547 42541546
Unevaluable event 15.11 12.10 51 26191 34237 42560856
Memory impairment 14.99 12.10 66 26176 50156 42544937
Hospice care 14.81 12.10 22 26220 8491 42586602
Mental status changes 14.64 12.10 58 26184 42057 42553036
Influenza like illness 14.60 12.10 48 26194 31792 42563301
Overdose 14.20 12.10 27 26215 105237 42489856
Foetal exposure during pregnancy 13.66 12.10 6 26236 47305 42547788
Haemoglobin decreased 13.65 12.10 133 26109 132338 42462755
Muscular weakness 13.57 12.10 93 26149 83405 42511688
Atelectasis 13.57 12.10 34 26208 19327 42575766
Weight decreased 13.51 12.10 191 26051 207757 42387336
Decreased appetite 13.19 12.10 179 26063 192958 42402135
Drug ineffective for unapproved indication 13.10 12.10 6 26236 46157 42548936
Suicide attempt 13.07 12.10 6 26236 46094 42548999
Platelet count decreased 12.78 12.10 136 26106 138445 42456648
Hepatic function abnormal 12.73 12.10 8 26234 51559 42543534
Drug reaction with eosinophilia and systemic symptoms 12.69 12.10 5 26237 42070 42553023

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Blepharospasm 198.76 10.65 230 86524 54621 110447924
Onychomadesis 197.40 10.65 210 86544 45453 110457092
Onychomycosis 185.98 10.65 188 86566 38343 110464202
Toxicity to various agents 173.48 10.65 80 86674 480475 110022070
Completed suicide 160.22 10.65 7 86747 242374 110260171
Taste disorder 154.72 10.65 222 86532 65165 110437380
Off label use 132.64 10.65 667 86087 1499518 109003027
Gastrooesophageal reflux disease 129.89 10.65 372 86382 179604 110322941
Product quality issue 124.30 10.65 220 86534 77079 110425466
Drug interaction 122.53 10.65 127 86627 500056 110002489
Injection site reaction 120.06 10.65 235 86519 88835 110413710
Memory impairment 111.42 10.65 374 86380 196570 110305975
Muscle spasms 106.14 10.65 466 86288 277691 110224854
Epilepsy 95.66 10.65 230 86524 99979 110402566
Back injury 95.08 10.65 149 86605 47250 110455295
Nail disorder 93.28 10.65 165 86589 57770 110444775
Migraine 91.85 10.65 320 86434 171332 110331213
Breast cancer stage III 85.86 10.65 191 86563 78926 110423619
Depression 81.78 10.65 476 86278 316859 110185686
Drug ineffective 79.09 10.65 788 85966 1519752 108982793
Psoriatic arthropathy 73.76 10.65 328 86426 196433 110306112
Grip strength decreased 73.30 10.65 181 86573 79993 110422552
Rheumatic fever 73.06 10.65 237 86517 122342 110380203
Intentional overdose 72.98 10.65 9 86745 132492 110370053
Hypercholesterolaemia 70.64 10.65 193 86561 90644 110411901
Facet joint syndrome 69.67 10.65 200 86554 96628 110405917
COVID-19 68.52 10.65 55 86699 245005 110257540
Peripheral venous disease 67.70 10.65 181 86573 83936 110418609
Hypocholesterolaemia 67.52 10.65 49 86705 6372 110496173
Asthenia 64.43 10.65 824 85930 688175 109814370
Finger deformity 63.57 10.65 102 86652 32990 110469555
Product label confusion 59.60 10.65 81 86673 22596 110479949
Dry mouth 58.87 10.65 311 86443 199637 110302908
Adverse reaction 55.19 10.65 90 86664 29504 110473041
Night sweats 52.21 10.65 226 86528 133757 110368788
Dizziness 51.94 10.65 802 85952 697391 109805154
Sleep disorder 51.80 10.65 299 86455 198345 110304200
Fall 51.09 10.65 709 86045 602773 109899772
Wound infection 48.29 10.65 176 86578 96289 110406256
Device expulsion 47.19 10.65 86 86668 30805 110471740
Type 2 diabetes mellitus 46.36 10.65 267 86487 176965 110325580
Joint range of motion decreased 46.32 10.65 204 86550 121628 110380917
Liver function test increased 45.55 10.65 163 86591 88385 110414160
Suicide attempt 44.34 10.65 13 86741 103381 110399164
Blood cholesterol increased 44.24 10.65 272 86482 184513 110318032
Hypoaesthesia 43.74 10.65 407 86347 313816 110188729
Lip dry 42.24 10.65 173 86581 99910 110402635
Abdominal distension 42.07 10.65 258 86496 174845 110327700
Acute kidney injury 41.44 10.65 310 86444 635120 109867425
Live birth 41.08 10.65 134 86620 69350 110433195
Product dose omission issue 40.95 10.65 409 86345 321373 110181172
Bursitis 38.85 10.65 203 86551 129715 110372830
Multiple organ dysfunction syndrome 38.82 10.65 37 86717 151673 110350872
Ill-defined disorder 38.24 10.65 232 86522 156621 110345924
Plasma cell myeloma 37.77 10.65 122 86632 62814 110439731
Neck pain 37.24 10.65 193 86561 122937 110379608
Paraesthesia 36.90 10.65 355 86399 276166 110226379
Injury 36.36 10.65 251 86503 177014 110325531
Coeliac disease 35.83 10.65 94 86660 43093 110459452
Intentional product misuse 35.69 10.65 31 86723 132873 110369672
Interstitial lung disease 35.63 10.65 34 86720 139300 110363245
Hepatic function abnormal 35.17 10.65 13 86741 89282 110413263
Drug reaction with eosinophilia and systemic symptoms 33.98 10.65 11 86743 82084 110420461
Diarrhoea 33.74 10.65 1149 85605 1138356 109364189
Febrile neutropenia 33.71 10.65 131 86623 316636 110185909
Coma 33.50 10.65 26 86728 117843 110384702
Obesity 32.45 10.65 175 86579 113176 110389369
Abdominal pain upper 31.89 10.65 416 86338 348695 110153850
Eosinophilia 31.74 10.65 4 86750 57932 110444613
Fatigue 30.38 10.65 1203 85551 1214755 109287790
Gait inability 30.31 10.65 197 86557 136179 110366366
Musculoskeletal pain 30.10 10.65 246 86508 182777 110319768
Wound 29.82 10.65 298 86456 234139 110268406
Cholestasis 29.78 10.65 7 86747 64511 110438034
Therapy cessation 29.72 10.65 90 86664 44767 110457778
Liver injury 29.68 10.65 211 86543 150202 110352343
Pyrexia 29.67 10.65 511 86243 897754 109604791
Asthma 29.61 10.65 99 86655 250192 110252353
Cytomegalovirus infection 29.25 10.65 4 86750 54440 110448105
Sleep disorder due to general medical condition, insomnia type 29.15 10.65 24 86730 105619 110396926
Obstructive defaecation 29.05 10.65 10 86744 252 110502293
Full blood count decreased 28.84 10.65 72 86682 32027 110470518
C-reactive protein abnormal 28.61 10.65 187 86567 129508 110373037
Pericarditis 28.58 10.65 280 86474 218834 110283711
Drug resistance 28.33 10.65 5 86749 56369 110446176
C-reactive protein increased 28.19 10.65 278 86476 217641 110284904
Visual snow syndrome 27.95 10.65 7 86747 54 110502491
Agranulocytosis 27.92 10.65 7 86747 61753 110440792
Muscular weakness 27.91 10.65 308 86446 248160 110254385
Stoma site dermatitis 27.76 10.65 10 86744 289 110502256
Lactic acidosis 26.98 10.65 20 86734 92791 110409754
Cytokine release syndrome 26.43 10.65 11 86743 70295 110432250
Renal impairment 26.29 10.65 69 86685 188376 110314169
Impaired healing 25.47 10.65 251 86503 196466 110306079
Therapeutic response decreased 25.32 10.65 23 86731 96476 110406069
Thrombocytopenia 25.26 10.65 165 86589 348720 110153825
Fibromyalgia 25.09 10.65 224 86530 170685 110331860
Illness 24.82 10.65 17 86737 82154 110420391
Gastrointestinal stoma output abnormal 24.19 10.65 10 86744 422 110502123
Folliculitis 23.73 10.65 218 86536 167435 110335110
Depressed level of consciousness 23.70 10.65 32 86722 112246 110390299
Dyspepsia 23.44 10.65 241 86513 190724 110311821
Altered state of consciousness 23.36 10.65 8 86746 57618 110444927
Device dislocation 23.29 10.65 66 86688 31638 110470907
Drug ineffective for unapproved indication 23.06 10.65 28 86726 102810 110399735
Irritable bowel syndrome 22.97 10.65 213 86541 164002 110338543
Rhabdomyolysis 22.80 10.65 37 86717 120364 110382181
Leukopenia 22.70 10.65 52 86702 148739 110353806
Osteoarthritis 22.19 10.65 230 86524 182393 110320152
Unevaluable event 21.62 10.65 98 86656 59129 110443416
Cardiogenic shock 21.51 10.65 9 86745 57329 110445216
Diabetes mellitus 21.30 10.65 28 86726 99353 110403192
Anaphylactic shock 21.17 10.65 7 86747 51539 110451006
Flatulence 21.10 10.65 89 86665 52060 110450485
Neutropenia 21.07 10.65 190 86564 374430 110128115
Peripheral swelling 21.04 10.65 439 86315 403595 110098950
Pemphigus 20.98 10.65 259 86495 214311 110288234
Cardiac failure 20.98 10.65 76 86678 187550 110314995
Underdose 20.89 10.65 102 86652 63452 110439093
Deep vein thrombosis 20.87 10.65 184 86570 139703 110362842
Anaphylactic reaction 20.83 10.65 36 86718 114264 110388281
Hospice care 20.69 10.65 36 86718 12437 110490108
Infusion site reaction 20.67 10.65 44 86710 17638 110484907
Neurotoxicity 20.66 10.65 4 86750 42203 110460342
Normal newborn 20.61 10.65 50 86704 21846 110480699
Blood pressure systolic increased 20.35 10.65 21 86733 82970 110419575
Overdose 19.88 10.65 105 86649 233689 110268856
Angioedema 19.86 10.65 29 86725 98471 110404074
Cardio-respiratory arrest 19.76 10.65 38 86716 115798 110386747
Headache 19.47 10.65 862 85892 881515 109621030
Obstructive airways disorder 19.42 10.65 6 86748 46143 110456402
Drug eruption 19.22 10.65 9 86745 53650 110448895
Shock 19.17 10.65 9 86745 53579 110448966
Hypervolaemia 18.93 10.65 83 86671 49377 110453168
Lung disorder 18.77 10.65 220 86534 179827 110322718
Infection 18.54 10.65 188 86566 362012 110140533
Accidental exposure to product 18.52 10.65 8 86746 50000 110452545
Stoma site inflammation 18.48 10.65 11 86743 1024 110501521
Stoma site pain 18.44 10.65 14 86740 1949 110500596
Inflammation 18.36 10.65 232 86522 193006 110309539
Confusional state 18.21 10.65 489 86265 468191 110034354
Erythema 18.10 10.65 144 86610 291303 110211242
Gamma-glutamyltransferase increased 18.10 10.65 13 86741 61296 110441249
Cardiac arrest 18.08 10.65 86 86668 196667 110305878
Dislocation of vertebra 17.99 10.65 75 86679 43646 110458899
Adverse drug reaction 17.95 10.65 143 86611 105416 110397129
Nausea 17.84 10.65 1160 85594 1234530 109268015
Sedation 17.82 10.65 17 86737 69666 110432879
Metabolic acidosis 17.65 10.65 32 86722 99712 110402833
Condition aggravated 17.44 10.65 441 86313 734395 109768150
Malignant neoplasm progression 17.42 10.65 74 86680 174493 110328052
Rheumatoid arthritis 17.42 10.65 331 86423 299282 110203263
Circulatory collapse 17.37 10.65 6 86748 42987 110459558
Product use in unapproved indication 17.25 10.65 247 86507 447130 110055415
Pneumocystis jirovecii pneumonia 17.21 10.65 6 86748 42729 110459816
Feeling abnormal 17.18 10.65 217 86537 180494 110322051
Septic shock 16.84 10.65 65 86689 157463 110345082
Fluid retention 16.72 10.65 129 86625 94178 110408367
Therapeutic product effect decreased 16.72 10.65 277 86477 244039 110258506
Insomnia 16.30 10.65 384 86370 360206 110142339
Bradycardia 16.09 10.65 65 86689 155452 110347093
Pruritus 16.03 10.65 341 86413 581219 109921326
Mucosal inflammation 16.00 10.65 32 86722 96109 110406436
Rash maculo-papular 15.82 10.65 21 86733 74201 110428344
Osteonecrosis of jaw 15.79 10.65 9 86745 48008 110454537
Polyneuropathy 15.74 10.65 3 86751 32009 110470536
Serotonin syndrome 15.63 10.65 14 86740 59139 110443406
Tubulointerstitial nephritis 15.39 10.65 12 86742 54272 110448273
Abdominal discomfort 14.74 10.65 409 86345 393449 110109096
Disseminated intravascular coagulation 14.67 10.65 7 86747 41279 110461266
Pelvic pain 14.57 10.65 36 86718 15906 110486639
Blood pressure diastolic decreased 14.51 10.65 5 86749 35880 110466665
Hepatic enzyme 14.42 10.65 19 86735 5144 110497401
Impaired quality of life 14.37 10.65 3 86751 30014 110472531
Toxic epidermal necrolysis 14.32 10.65 14 86740 56713 110445832
Helicobacter infection 14.26 10.65 211 86543 181666 110320879
Muscle injury 14.21 10.65 171 86583 140636 110361909
Hepatic failure 14.09 10.65 20 86734 68719 110433826
Neoplasm progression 14.05 10.65 18 86736 64577 110437968
Cerebral infarction 14.02 10.65 12 86742 51826 110450719
Gastrointestinal stoma complication 13.98 10.65 15 86739 3274 110499271
Hyperkalaemia 13.90 10.65 57 86697 135739 110366806
Hypokalaemia 13.85 10.65 85 86669 182363 110320182
Intentional self-injury 13.84 10.65 6 86748 37423 110465122
Bone marrow failure 13.78 10.65 15 86739 57833 110444712
Thrombotic microangiopathy 13.78 10.65 3 86751 29146 110473399
Hyponatraemia 13.76 10.65 107 86647 217546 110284999
Respiratory depression 13.76 10.65 4 86750 31997 110470548
Poisoning 13.75 10.65 3 86751 29102 110473443
Gait disturbance 13.73 10.65 300 86454 277908 110224637
COVID-19 pneumonia 13.66 10.65 6 86748 37137 110465408
Swelling 13.55 10.65 366 86388 350675 110151870
Hepatotoxicity 13.45 10.65 18 86736 63382 110439163
Dehydration 13.35 10.65 300 86454 279211 110223334
Neuroleptic malignant syndrome 13.34 10.65 5 86749 34054 110468491
Blood pressure fluctuation 13.24 10.65 24 86730 74800 110427745
Acute hepatic failure 13.24 10.65 6 86748 36462 110466083
Adverse event 13.19 10.65 137 86617 108672 110393873
Respiratory sinus arrhythmia magnitude 13.04 10.65 4 86750 69 110502476
Spondylitis 13.01 10.65 28 86726 11310 110491235
Hypoglycaemia 13.00 10.65 47 86707 116057 110386488
Ulcer haemorrhage 12.86 10.65 43 86711 22528 110480017
Mobility decreased 12.68 10.65 259 86495 237163 110265382
Acute respiratory distress syndrome 12.45 10.65 14 86740 53184 110449361
Underweight 12.40 10.65 10 86744 1520 110501025
Dyspnoea 12.35 10.65 1018 85736 1105854 109396691
Small intestinal obstruction 12.28 10.65 54 86700 32159 110470386
Lumbar vertebral fracture 12.18 10.65 24 86730 9107 110493438
Agitation 11.85 10.65 47 86707 113004 110389541
Hiccups 11.70 10.65 29 86725 12840 110489705
Hepatitis 11.69 10.65 115 86639 89939 110412606
Blindness 11.69 10.65 7 86747 36352 110466193
Aspergillus infection 11.39 10.65 3 86751 25613 110476932
Adjustment disorder with depressed mood 11.39 10.65 66 86688 43817 110458728
Neutropenic sepsis 11.25 10.65 5 86749 30741 110471804
Eczema 11.24 10.65 25 86729 72268 110430277
Premature delivery 11.18 10.65 5 86749 30627 110471918
Eructation 11.05 10.65 30 86724 14027 110488518
Hospitalisation 11.05 10.65 165 86589 142328 110360217
Respiratory arrest 10.95 10.65 18 86736 58281 110444264
Duodenal ulcer perforation 10.90 10.65 198 86556 177502 110325043
Glossodynia 10.83 10.65 239 86515 221765 110280780
Viral infection 10.74 10.65 75 86679 53064 110449481
Blood potassium decreased 10.72 10.65 76 86678 54038 110448507

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A06AD19 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR CONSTIPATION
DRUGS FOR CONSTIPATION
Osmotically acting laxatives
ATC A12CC04 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
OTHER MINERAL SUPPLEMENTS
Magnesium
ATC B05CB03 BLOOD AND BLOOD FORMING ORGANS
BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
IRRIGATING SOLUTIONS
Salt solutions
MeSH PA D002400 Cathartics
MeSH PA D005765 Gastrointestinal Agents
CHEBI has role CHEBI:50503 laxative
CHEBI has role CHEBI:64049 food acidity regulator

Related Drugs by ATC class:

A06AD Osmotically acting laxatives 13 drugs
lactitollactulosemacrogolmagnesium carbonatemagnesium oxidemagnesium peroxidemagnesium sulfatemannitolpentaerythritolsodium phosphatesodium sulfatesodium tartrate show all 13 →
A12CC Magnesium 9 drugs
magnesium aspartatemagnesium chloridemagnesium gluconatemagnesium lactatemagnesium levulinatemagnesium orotatemagnesium oxidemagnesium pidolatemagnesium sulfate
B05CB Salt solutions 3 drugs
sodium bicarbonatesodium chloridesodium citrate

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypocalcemia indication 5291005
Constipation indication 14760008 DOID:2089
Osteoporosis indication 64859006 DOID:11476
Postmenopausal osteoporosis indication 102447009
Incomplete passage of stool indication 249515001
Peptic ulcer contraindication 13200003 DOID:750
Hyperkalemia contraindication 14140009
Hyperphosphatemia contraindication 20165001 DOID:0050459
Hypervitaminosis D contraindication 27712000 DOID:9971
Sarcoidosis contraindication 31541009 DOID:11335
Dehydration contraindication 34095006
Chronic heart failure contraindication 48447003
Metabolic acidosis contraindication 59455009
Diarrhea contraindication 62315008
Hypercalcemia contraindication 66931009 DOID:12678
Hypermagnesemia contraindication 66978005
Hyperparathyroidism contraindication 66999008 DOID:13543
Hypercalciuria contraindication 71938000
Appendicitis contraindication 74400008 DOID:8337
Gastrointestinal hemorrhage contraindication 74474003
Kidney disease contraindication 90708001 DOID:557
Kidney stone contraindication 95570007
Gastrointestinal obstruction contraindication 126765001
Impaired renal function disorder contraindication 197663003
Gastroparesis contraindication 235675006
Rhabdomyolysis contraindication 240131006
Esophageal dysmotility contraindication 266434009 DOID:9192
Arteriosclerosis obliterans contraindication 361133006 DOID:5160
Primary adrenocortical insufficiency contraindication 373662000
Ketoacidosis in diabetes mellitus contraindication 420422005 DOID:1837
Esophageal Compression contraindication
Genitourinary Tract Infections contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019514 VUID
N0000147634 NUI
D03265 KEGG_DRUG
4019514 VANDF
C0126774 UMLSCUI
CHEBI:131391 CHEBI
CHEMBL3989480 ChEMBL_ID
DB11110 DRUGBANK_ID
C110422 MESH_SUPPLEMENTAL_RECORD_UI
RHO26O1T9V UNII
6099959 PUBCHEM_CID
52356 RXNORM
28364 MMSL
5011 MMSL
5563 MMSL
d01008 MMSL
001185 NDDF
006958 NDDF
008279 NDDF
12495006 SNOMEDCT_US
387052002 SNOMEDCT_US
RHO26O1T9V INXIGHT DRUGS

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0415 LIQUID 1.75 g ORAL OTC Monograph Drug 16 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0416 LIQUID 1.75 g ORAL OTC Monograph Drug 16 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0427 LIQUID 1.75 g ORAL OTC Monograph Drug 16 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-6350 LIQUID 1.75 g ORAL OTC Monograph Drug 14 sections
citroma HUMAN OTC DRUG LABEL 1 0869-0164 LIQUID 1.75 g ORAL OTC Monograph Drug 16 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0904-7418 LIQUID 1.75 g ORAL OTC Monograph Drug 12 sections
Citroma HUMAN OTC DRUG LABEL 1 11344-162 LIQUID 1.75 g ORAL OTC Monograph Drug 16 sections
Citroma HUMAN OTC DRUG LABEL 1 11344-164 LIQUID 1.75 g ORAL OTC Monograph Drug 16 sections
citroma HUMAN OTC DRUG LABEL 1 11344-166 LIQUID 1.75 g ORAL OTC Monograph Drug 16 sections
citroma HUMAN OTC DRUG LABEL 1 11673-708 LIQUID 1.75 g ORAL OTC Monograph Drug 17 sections
citroma HUMAN OTC DRUG LABEL 1 11822-4330 LIQUID 1.75 g ORAL OTC Monograph Drug 15 sections
citroma HUMAN OTC DRUG LABEL 1 21130-165 LIQUID 1.75 g ORAL OTC Monograph Drug 15 sections
citroma HUMAN OTC DRUG LABEL 1 21130-709 LIQUID 1.75 g ORAL OTC Monograph Drug 15 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 21695-934 LIQUID 2.62 g ORAL OTC monograph not final 14 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 30142-164 LIQUID 1.75 g ORAL OTC Monograph Drug 17 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 30142-899 LIQUID 1.75 g ORAL OTC Monograph Drug 17 sections
citroma HUMAN OTC DRUG LABEL 1 36800-164 LIQUID 1.75 g ORAL OTC Monograph Drug 16 sections
citroma HUMAN OTC DRUG LABEL 1 36800-709 LIQUID 1.75 g ORAL OTC Monograph Drug 16 sections
citroma HUMAN OTC DRUG LABEL 1 41163-709 LIQUID 1.75 g ORAL OTC Monograph Drug 17 sections
citroma HUMAN OTC DRUG LABEL 1 41163-769 LIQUID 1.75 g ORAL OTC Monograph Drug 17 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 42507-249 LIQUID 1.75 g ORAL OTC Monograph Drug 16 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 46122-740 LIQUID 1.75 g ORAL OTC Monograph Drug 16 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 46122-741 LIQUID 1.75 g ORAL OTC Monograph Drug 16 sections
citroma HUMAN OTC DRUG LABEL 1 50804-164 LIQUID 1.75 g ORAL OTC Monograph Drug 17 sections
citroma HUMAN OTC DRUG LABEL 1 50804-166 LIQUID 1.75 g ORAL OTC Monograph Drug 17 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 51316-880 LIQUID 1.75 g ORAL OTC Monograph Drug 12 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 51316-881 LIQUID 1.75 g ORAL OTC Monograph Drug 12 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 51316-882 LIQUID 1.75 g ORAL OTC Monograph Drug 12 sections
Magnesium Citrate Saline Laxative - Lemon Flavor HUMAN OTC DRUG LABEL 1 52000-449 SOLUTION 0.06 g ORAL OTC Monograph Drug 10 sections
Magnesium Citrate Saline Laxative - Grape Flavor HUMAN OTC DRUG LABEL 1 52000-450 SOLUTION 0.06 g ORAL OTC Monograph Drug 10 sections