methylprednisolone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
prednisone and prednisolone derivatives 1768 83-43-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • methylprednisolone
  • medralone
  • metilbetasone
A PREDNISOLONE derivative with similar anti-inflammatory action.
  • Molecular weight: 374.48
  • Formula: C22H30O5
  • CLOGP: 1.74
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 3
  • TPSA: 94.83
  • ALOGS: -3.54
  • ROTB: 2
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

DoseUnitRoute
7.50 mg O
20 mg P

ADMET properties:

PropertyValueReference
BDDCS (Biopharmaceutical Drug Disposition Classification System) 2 Bocci G, Oprea TI, Benet LZ
S (Water solubility) 0.12 mg/mL Bocci G, Oprea TI, Benet LZ
EoM (Fraction excreted unchanged in urine) 4.90 % Benet LZ, Broccatelli F, Oprea TI
MRTD (Maximum Recommended Therapeutic Daily Dose) 11.14 µM/kg/day Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
BA (Bioavailability) 82 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H
Vd (Volume of distribution) 1.20 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 6.10 mL/min/kg Lombardo F, Berellini G, Obach RS
fu (Fraction unbound in plasma) 0.23 % Lombardo F, Berellini G, Obach RS
t_half (Half-life) 2.30 hours Lombardo F, Berellini G, Obach RS

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
azlogd74 LogD at pH 7.4 2.098 High 1
caco2-efflux Caco-2 efflux ratio (BA/AB) 4.909 High 1
caco2-intrinsic-papp Caco-2 intrinsic apparent permeability 40.179 10^-6 cm/s High 1
dh-clint Dog hepatocyte intrinsic clearance 8.690 uL/min/10^6 cells High 1
dppb Dog plasma protein binding (% unbound) 23.190 % High 1
fcs-ppb Fetal calf serum protein binding (% unbound) 44.270 % High 1
herg hERG pIC50 4.442 pIC50 High 1
hh-clint Human hepatocyte intrinsic clearance 5.047 uL/min/10^6 cells High 1
hlm-clint Human liver microsomal intrinsic clearance 33.806 uL/min/mg protein High 1
hppb Human plasma protein binding (% unbound) 15.610 % High 1
kinase-safety-class ACVR2B,CDK5,EIF2AK3,GRK2,ITK,MAPK10,PDK1,PDK2,PDK4,PRKDC 10
kinase-selectivity-class GRK2,MAP2K6 2
mdck-mdr1-bcrp-efflux MDCK-MDR1-BCRP efflux ratio 9.705 Moderate 0.68
mdck-mdr1-efflux MDCK-MDR1 efflux ratio 11.803 High 1
mh-clint Mouse hepatocyte intrinsic clearance 32.961 High 1
mppb Mouse plasma protein binding (% unbound) 20 High 1
nih-mdck-mdr1-efflux NIH MDCK-MDR1 efflux ratio 23.121 High 1
pfas-class PFAS structural alert (1 = True, 0 = False) 0
pld-class Phospholipidosis risk class (1 = positive, 0 = negative) 0 Moderate 0.68
pppb Pig plasma protein binding (% unbound) 31.920 % High 1
rat-kpuu-brain Rat brain Kpuu 0.047 % Moderate 0.68
rh-clint Rat hepatocyte intrinsic clearance 76.736 uL/min/10^6 cells High 1
rh-fuinc Rat hepatocyte fraction unbound in incubation 72.450 % High 1
rppb Rat plasma protein binding (% unbound) 18.810 % High 1
solubility-dd Solubility at pH 7.4 in DMSO 246.604 uM High 1

Approvals:

DateAgencyCompanyOrphan
Oct. 24, 1957 FDA PHARMACIA AND UPJOHN

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Off label use 1175.54 9.05 6874 290465 1095378 89235730
Cytomegalovirus infection 1105.16 9.05 820 296519 25782 90305326
Drug ineffective for unapproved indication 604.24 9.05 908 296431 65736 90265372
Throat irritation 582.57 9.05 758 296581 47937 90283171
Blood pressure fluctuation 518.31 9.05 744 296595 51669 90279439
Transplant rejection 448.10 9.05 356 296983 12402 90318706
Completed suicide 405.99 9.05 16 297323 145042 90186066
Bronchopulmonary aspergillosis 372.64 9.05 305 297034 11093 90320015
Aspergillus infection 350.45 9.05 288 297051 10535 90320573
Cytomegalovirus infection reactivation 345.48 9.05 250 297089 7550 90323558
Haemophagocytic lymphohistiocytosis 331.40 9.05 326 297013 15133 90315975
Rheumatoid factor positive 329.39 9.05 79 297260 171571 90159537
Posterior reversible encephalopathy syndrome 328.76 9.05 386 296953 21953 90309155
Blood pressure systolic abnormal 312.64 9.05 352 296987 19126 90311982
Multiple organ dysfunction syndrome 312.48 9.05 692 296647 67644 90263464
Drug ineffective 306.33 9.05 6293 291046 1378005 88953103
Thrombotic microangiopathy 299.10 9.05 311 297028 15432 90315676
Sleep disorder due to general medical condition, insomnia type 295.40 9.05 37 297302 128657 90202451
Alopecia 292.91 9.05 754 296585 494317 89836791
Discomfort 285.65 9.05 287 297052 274048 90057060
Cytomegalovirus viraemia 282.20 9.05 219 297120 7367 90323741
Blood pressure diastolic abnormal 278.50 9.05 335 297004 19546 90311562
Klebsiella infection 278.25 9.05 247 297092 10050 90321058
BK virus infection 275.06 9.05 176 297163 4322 90326786
Pneumocystis jirovecii pneumonia 263.96 9.05 340 296999 21276 90309832
Oxygen saturation decreased 262.44 9.05 863 296476 106620 90224488
Polyomavirus-associated nephropathy 260.31 9.05 138 297201 2352 90328756
Ear pruritus 258.75 9.05 199 297140 6604 90324504
Epstein-Barr virus infection 257.63 9.05 237 297102 10107 90321001
Blood pressure increased 257.59 9.05 1304 296035 195913 90135195
Product use in unapproved indication 252.73 9.05 1928 295411 334308 89996800
Abdominal discomfort 246.93 9.05 775 296564 476553 89854555
Blood pressure systolic increased 246.91 9.05 573 296766 57772 90273336
Glossodynia 241.96 9.05 428 296911 321351 90009757
Wound 231.42 9.05 399 296940 302581 90028527
Respiratory failure 230.87 9.05 883 296456 117535 90213573
Death 230.72 9.05 749 296590 455802 89875306
Pemphigus 230.53 9.05 452 296887 326412 90004696
Post transplant lymphoproliferative disorder 220.99 9.05 183 297156 6766 90324342
COVID-19 220.17 9.05 1116 296223 167727 90163381
Enterococcal infection 216.59 9.05 212 297127 9779 90321329
Systemic lupus erythematosus 211.69 9.05 554 296785 361342 89969766
Kidney transplant rejection 209.04 9.05 153 297186 4704 90326404
Swelling 208.58 9.05 692 296647 418366 89912742
Blood pressure diastolic decreased 202.23 9.05 336 297003 26490 90304618
Nocardiosis 196.55 9.05 116 297223 2454 90328654
Hand deformity 196.10 9.05 425 296914 295937 90035171
Swollen joint count increased 194.90 9.05 61 297278 111145 90219963
Infusion related reaction 194.18 9.05 2156 295183 414624 89916484
Mucormycosis 191.31 9.05 132 297207 3689 90327419
Septic shock 188.89 9.05 657 296682 83503 90247605
Pseudomonas infection 188.10 9.05 238 297101 14627 90316481
Varicella zoster virus infection 184.91 9.05 130 297209 3747 90327361
Urine abnormality 184.44 9.05 173 297166 7564 90323544
Disease recurrence 182.01 9.05 390 296949 37263 90293845
Progressive multifocal leukoencephalopathy 181.44 9.05 240 297099 15415 90315693
Heart rate decreased 179.54 9.05 481 296858 53024 90278084
Arthropathy 178.64 9.05 610 296729 365632 89965476
Drug effective for unapproved indication 175.37 9.05 170 297169 7748 90323360
Synovitis 169.23 9.05 537 296802 329215 90001893
Intentional overdose 167.09 9.05 50 297289 93784 90237324
White blood cells urine positive 165.96 9.05 151 297188 6347 90324761
Systemic candida 162.73 9.05 133 297206 4826 90326282
Toxicity to various agents 162.71 9.05 448 296891 287398 90043710
Urine leukocyte esterase positive 161.08 9.05 112 297227 3170 90327938
Injection site pain 157.57 9.05 203 297136 173496 90157612
Pharyngeal paraesthesia 157.39 9.05 109 297230 3065 90328043
Complications of transplanted kidney 157.38 9.05 105 297234 2773 90328335
Lymphocyte count decreased 156.89 9.05 352 296987 34698 90296410
Escherichia infection 156.15 9.05 225 297114 15670 90315438
Contraindicated product administered 155.55 9.05 534 296805 319605 90011503
Contusion 152.66 9.05 377 296962 250839 90080269
Adenovirus infection 149.65 9.05 123 297216 4499 90326609
Pericarditis 149.31 9.05 425 296914 269726 90061382
Cushingoid 146.96 9.05 176 297163 10219 90320889
Heart rate increased 145.53 9.05 744 296595 112158 90218950
Red blood cells urine positive 144.27 9.05 104 297235 3121 90327987
Acinetobacter infection 141.54 9.05 86 297253 1922 90329186
Delayed graft function 140.61 9.05 76 297263 1349 90329759
Knee arthroplasty 138.14 9.05 50 297289 83132 90247976
Pneumomediastinum 138.09 9.05 85 297254 1946 90329162
Product dose omission issue 138.02 9.05 492 296847 291195 90039913
Lymphopenia 136.88 9.05 259 297080 22622 90308486
Decreased appetite 136.52 9.05 703 296636 375837 89955271
Lower limb fracture 136.34 9.05 54 297285 84959 90246149
Cytomegalovirus colitis 135.28 9.05 102 297237 3284 90327824
Hospitalisation 133.24 9.05 134 297205 127966 90203142
Fatigue 132.80 9.05 2834 294505 1151189 89179919
Acute graft versus host disease in skin 130.32 9.05 115 297224 4641 90326467
Road traffic accident 129.60 9.05 98 297241 107528 90223580
Candida infection 129.56 9.05 321 297018 33736 90297372
Rheumatoid arthritis 128.70 9.05 1783 295556 360831 89970277
Adverse drug reaction 128.48 9.05 116 297223 116585 90214523
Oedema 126.89 9.05 294 297045 200001 90131107
Steroid diabetes 124.25 9.05 86 297253 2416 90328692
Drug intolerance 124.02 9.05 909 296430 446682 89884426
Pneumatosis intestinalis 123.03 9.05 97 297242 3340 90327768
Vomiting 122.16 9.05 1836 295503 786457 89544651
Thrombocytopenia 121.60 9.05 1131 296208 207594 90123514
Adverse event 120.79 9.05 124 297215 117294 90213814
Wrong technique in product usage process 120.59 9.05 42 297297 71529 90259579
Graft versus host disease in gastrointestinal tract 118.04 9.05 105 297234 4283 90326825
Osteonecrosis 117.96 9.05 264 297075 25977 90305131
Deep vein thrombosis postoperative 116.84 9.05 43 297296 70766 90260342
Herpes simplex 116.32 9.05 155 297184 10026 90321082
Coeliac disease 115.91 9.05 366 296973 44244 90286864
Duodenal ulcer perforation 115.83 9.05 357 296982 220931 90110177
Reversible cerebral vasoconstriction syndrome 115.45 9.05 101 297238 4029 90327079
Myopathy 115.13 9.05 179 297160 13339 90317769
Hip arthroplasty 114.88 9.05 53 297286 76155 90254953
Oedema peripheral 114.19 9.05 447 296892 257468 90073640
Device expulsion 112.72 9.05 5 297334 40881 90290227
Human herpesvirus 6 infection 112.52 9.05 92 297247 3340 90327768
Helicobacter infection 112.44 9.05 375 296964 226475 90104633
Immunosuppressant drug level increased 112.24 9.05 105 297234 4575 90326533
Electric shock 111.84 9.05 70 297269 1652 90329456
Pneumonia cytomegaloviral 111.79 9.05 88 297251 3023 90328085
Urinary sediment present 110.96 9.05 76 297263 2098 90329010
Back injury 110.76 9.05 371 296968 46251 90284857
Sepsis 108.08 9.05 981 296358 178833 90152275
Onychomycosis 107.72 9.05 318 297021 37058 90294050
Polyomavirus viraemia 107.47 9.05 62 297277 1255 90329853
Rebound effect 107.42 9.05 143 297196 9241 90321867
Acute respiratory distress syndrome 106.62 9.05 268 297071 28418 90302690
Finger deformity 106.61 9.05 292 297047 32605 90298503
Pulmonary nocardiosis 106.04 9.05 52 297287 746 90330362
Adjustment disorder with depressed mood 105.19 9.05 28 297311 56725 90274383
Erythema 104.77 9.05 1182 296157 228064 90103044
Graft versus host disease 104.00 9.05 131 297208 8013 90323095
Premature delivery 103.45 9.05 321 297018 38441 90292667
Diarrhoea 103.34 9.05 2322 295017 936868 89394240
Hypogammaglobulinaemia 103.25 9.05 150 297189 10524 90320584
Onychomadesis 102.24 9.05 358 296981 45640 90285468
Intervertebral discitis 101.90 9.05 98 297241 4422 90326686
Drug abuse 101.71 9.05 73 297266 82274 90248834
Pulmonary mucormycosis 100.93 9.05 46 297293 554 90330554
Cardiac failure congestive 99.51 9.05 106 297233 98588 90232520
Stomatitis 98.30 9.05 515 296824 274183 90056925
Viral haemorrhagic cystitis 95.23 9.05 60 297279 1433 90329675
Confusional state 95.01 9.05 810 296529 385395 89945713
Irritable bowel syndrome 94.73 9.05 355 296984 207093 90124015
Dehydration 94.60 9.05 324 297015 194123 90136985
Infective aneurysm 94.49 9.05 40 297299 398 90330710
Autoimmune disorder 93.52 9.05 69 297270 76675 90254433
Liver disorder 93.13 9.05 159 297180 121110 90209998
Anti-cyclic citrullinated peptide antibody positive 92.80 9.05 429 296910 236004 90095104
Acute graft versus host disease in intestine 92.79 9.05 67 297272 2016 90329092
COVID-19 pneumonia 92.16 9.05 192 297147 17985 90313123
Suicide attempt 90.33 9.05 69 297270 75330 90255778
Muscle injury 90.31 9.05 288 297051 176366 90154742
Cytomegalovirus test positive 88.89 9.05 82 297257 3509 90327599
Stenotrophomonas infection 87.58 9.05 70 297269 2459 90328649
Leukopenia 86.70 9.05 597 296742 100113 90230995
Renal transplant failure 86.32 9.05 51 297288 1081 90330027
Crystal urine present 85.45 9.05 56 297283 1434 90329674
Peripheral swelling 84.77 9.05 906 296433 412200 89918908
Strongyloidiasis 84.13 9.05 57 297282 1545 90329563
Blood urine present 83.53 9.05 179 297160 17099 90314009
Wheezing 83.13 9.05 450 296889 237630 90093478
Blister 82.56 9.05 494 296845 254504 90076604
Sciatica 82.45 9.05 128 297211 101254 90229854
Systemic mycosis 79.31 9.05 54 297285 1476 90329632
Perinephric abscess 78.98 9.05 32 297307 282 90330826
Neutrophil count increased 78.27 9.05 187 297152 19203 90311905
Enterobacter infection 77.95 9.05 66 297273 2517 90328591
Pregnancy 77.95 9.05 54 297285 61993 90269115
Chest pain 77.87 9.05 672 296667 318973 90012135
Ureaplasma infection 77.59 9.05 44 297295 861 90330247
Drug-induced liver injury 77.51 9.05 535 296804 89783 90241325
Prescribed underdose 77.40 9.05 79 297260 74940 90256168
Pain 76.26 9.05 2592 294747 993749 89337359
Chorioretinopathy 76.03 9.05 43 297296 837 90330271
Sinusitis 75.91 9.05 739 296600 342349 89988759
Therapy partial responder 75.79 9.05 200 297139 21843 90309265
Liver transplant rejection 75.65 9.05 55 297284 1673 90329435
Herpes zoster 75.61 9.05 551 296788 94093 90237015
Injection site erythema 74.85 9.05 130 297209 98372 90232736
Disseminated intravascular coagulation 74.65 9.05 196 297143 21342 90309766
Constipation 74.45 9.05 576 296763 279819 90051289
Amnesia 73.86 9.05 153 297186 108352 90222756
Drug resistance 73.83 9.05 244 297095 30205 90300903
Serotonin syndrome 73.50 9.05 17 297322 37870 90293238
Sedation 73.38 9.05 33 297306 48138 90282970
Nausea 73.25 9.05 2941 294398 1107375 89223733
Pleocytosis 73.19 9.05 44 297295 964 90330144
Demyelination 72.43 9.05 110 297229 8030 90323078
Infection reactivation 72.14 9.05 56 297283 1884 90329224
Malignant neoplasm progression 71.64 9.05 152 297187 106718 90224390
JC virus infection 71.04 9.05 64 297275 2655 90328453
Bacterial test 70.94 9.05 45 297294 1088 90330020
Parvovirus B19 infection 70.69 9.05 43 297296 963 90330145
Temperature regulation disorder 70.44 9.05 151 297188 14428 90316680
Macular degeneration 69.86 9.05 19 297320 37951 90293157
Accidental exposure to product 69.43 9.05 26 297313 42340 90288768
Incorrect route of product administration 69.18 9.05 40 297299 50586 90280522
Lupus nephritis 68.62 9.05 82 297257 4750 90326358
Pulmonary alveolar haemorrhage 68.04 9.05 91 297248 5907 90325201
Hepatitis 67.94 9.05 431 296908 70308 90260800
Immune thrombocytopenia 67.84 9.05 141 297198 13185 90317923
X-ray abnormal 67.82 9.05 32 297307 45392 90285716
Disseminated tuberculosis 67.80 9.05 68 297271 3231 90327877
Lower respiratory tract infection 67.44 9.05 513 296826 250146 90080962
Pulmonary fibrosis 67.09 9.05 159 297180 107344 90223764
Neck pain 67.05 9.05 619 296720 113344 90217764
Hypersensitivity 66.83 9.05 1069 296270 453608 89877500
C-reactive protein increased 66.31 9.05 897 296442 180492 90150616
Orthostatic hypotension 64.74 9.05 28 297311 41799 90289309
Urine ketone body present 64.58 9.05 59 297280 2493 90328615
Bacteraemia 64.51 9.05 190 297149 22110 90308998
Product label confusion 64.50 9.05 193 297146 22657 90308451
Immunodeficiency 64.37 9.05 297 297042 42937 90288171
Graft versus host disease in skin 64.17 9.05 71 297268 3782 90327326
Encephalitis 64.09 9.05 124 297215 11010 90320098
Therapeutic product effect decreased 63.45 9.05 593 296746 276978 90054130
Fibromyalgia 63.42 9.05 406 296933 205863 90125245
Depressed level of consciousness 62.99 9.05 88 297251 72696 90258412
Blood pressure diastolic increased 62.73 9.05 134 297205 12772 90318336
Pneumonia klebsiella 62.54 9.05 63 297276 3009 90328099
Disseminated aspergillosis 62.11 9.05 31 297308 463 90330645
Monocyte count increased 62.04 9.05 109 297230 8988 90322120
Bone erosion 61.64 9.05 50 297289 52971 90278137
Gastroenteritis rotavirus 61.44 9.05 25 297314 223 90330885
Staphylococcal bacteraemia 60.97 9.05 97 297242 7372 90323736
Encephalitis autoimmune 60.91 9.05 52 297287 2006 90329102
Nephropathy toxic 60.82 9.05 131 297208 12557 90318551
Epstein-Barr virus associated lymphoproliferative disorder 60.45 9.05 58 297281 2609 90328499
Intensive care unit acquired weakness 60.44 9.05 39 297300 972 90330136
Epstein-Barr virus infection reactivation 60.33 9.05 47 297292 1590 90329518
Injection site bruising 59.98 9.05 50 297289 52257 90278851
Dislocation of vertebra 59.97 9.05 57 297282 55911 90275197
Immunosuppressant drug level decreased 59.76 9.05 41 297298 1135 90329973
Drug tolerance decreased 59.26 9.05 16 297323 32114 90298994
Food allergy 58.97 9.05 201 297138 25277 90305831
Cystitis haemorrhagic 58.53 9.05 81 297258 5432 90325676
Hepatic cirrhosis 58.29 9.05 73 297266 63180 90267928
Protothecosis 57.58 9.05 29 297310 442 90330666
Rheumatic fever 57.04 9.05 283 297056 152838 90178270
Penicillium infection 56.93 9.05 25 297314 274 90330834
Human herpesvirus 8 infection 56.55 9.05 27 297312 364 90330744
Staphylococcal infection 56.09 9.05 310 297029 48129 90282979
Oral pruritus 55.52 9.05 58 297281 2893 90328215
Multiple sclerosis 55.36 9.05 209 297130 27631 90303477
Flushing 55.30 9.05 487 296852 88004 90243104
Coordination abnormal 55.27 9.05 175 297164 21181 90309927
Impaired healing 54.96 9.05 497 296842 233702 90097406
Delirium 54.83 9.05 168 297171 104191 90226917
Glomerulonephritis 54.64 9.05 53 297286 2417 90328691
Cough 54.61 9.05 1591 295748 367371 89963737
Pneumonia bacterial 54.51 9.05 126 297213 12664 90318444
Proteus infection 54.48 9.05 43 297296 1483 90329625
Lymphocyte percentage decreased 54.48 9.05 59 297280 3068 90328040
Granulomatosis with polyangiitis 54.45 9.05 54 297285 2531 90328577
Malacoplakia 54.43 9.05 25 297314 307 90330801
Pulmonary tuberculosis 54.31 9.05 73 297266 4761 90326347
Brain abscess 54.22 9.05 56 297283 2756 90328352
Herpes virus infection 53.62 9.05 84 297255 6300 90324808
Rash 53.37 9.05 2104 295235 793996 89537112
Chest discomfort 53.37 9.05 691 296648 137674 90193434
Acute graft versus host disease 53.12 9.05 77 297262 5391 90325717
Symptom masked 52.84 9.05 36 297303 985 90330123
Proteinuria 52.38 9.05 182 297157 23109 90307999
Cerebral aspergillosis 52.13 9.05 29 297310 546 90330562
Psoriatic arthropathy 52.09 9.05 488 296851 227847 90103261
Rash erythematous 51.98 9.05 379 296960 64725 90266383
C-reactive protein 51.82 9.05 19 297320 31348 90299760
Cytomegalovirus chorioretinitis 51.82 9.05 51 297288 2368 90328740
Pneumonia necrotising 51.58 9.05 30 297309 617 90330491
Folliculitis 51.36 9.05 426 296913 203927 90127181
Haemoglobin urine present 51.32 9.05 32 297307 750 90330358
Culture urine positive 51.20 9.05 63 297276 3762 90327346
Rectal haemorrhage 51.13 9.05 123 297216 82621 90248487
Staphylococcal sepsis 50.99 9.05 102 297237 9281 90321827
Acute graft versus host disease in liver 50.43 9.05 32 297307 774 90330334
Urine analysis abnormal 49.96 9.05 73 297266 5148 90325960
Graft versus host disease in liver 49.94 9.05 34 297305 929 90330179
Vasculitis 49.89 9.05 176 297163 22517 90308591
Fall 49.75 9.05 1202 296137 480608 89850500
Neutrophil percentage increased 49.44 9.05 55 297284 2948 90328160
Post-traumatic stress disorder 49.43 9.05 84 297255 6744 90324364
Lupus vulgaris 49.33 9.05 45 297294 45014 90286094
Exostosis 49.29 9.05 61 297278 53073 90278035
Interstitial lung disease 49.05 9.05 423 296916 75982 90255126
Medication error 48.33 9.05 131 297208 84521 90246587
Escherichia urinary tract infection 48.16 9.05 126 297213 13689 90317419
Bacterial test positive 48.09 9.05 74 297265 5465 90325643
Protein urine present 48.04 9.05 84 297255 6900 90324208
Granulocyte count increased 47.95 9.05 40 297299 1494 90329614
Hypoglycaemia 47.94 9.05 98 297241 69750 90261358
Anti-cyclic citrullinated peptide antibody 47.56 9.05 15 297324 27206 90303902
Cryptococcosis 47.32 9.05 39 297300 1432 90329676
Gastroenteritis norovirus 47.05 9.05 48 297291 2328 90328780
Blood calcium decreased 47.04 9.05 20 297319 30162 90300946
Renal impairment 46.95 9.05 541 296798 104880 90226228
Accidental overdose 46.92 9.05 17 297322 28256 90302852
Intestinal perforation 46.76 9.05 125 297214 13756 90317352
Red cell distribution width increased 46.36 9.05 115 297224 12092 90319016
Nephrotic syndrome 46.30 9.05 85 297254 7254 90323854
Frequent bowel movements 46.18 9.05 72 297267 56863 90274245
Blood immunoglobulin A increased 45.48 9.05 36 297303 1247 90329861
Injection site swelling 45.43 9.05 79 297260 59760 90271348
Epstein-Barr viraemia 45.27 9.05 38 297301 1432 90329676
Cataract 45.17 9.05 397 296942 71695 90259413
Intra-abdominal pressure increased 44.86 9.05 21 297318 270 90330838
Intentional self-injury 44.83 9.05 20 297319 29314 90301794
Opportunistic infection 44.70 9.05 45 297294 2148 90328960
Epilepsy 44.62 9.05 439 296900 81767 90249341
Device dislocation 44.27 9.05 24 297315 31458 90299650
Heart transplant rejection 44.25 9.05 30 297309 814 90330294
Pyelonephritis fungal 44.20 9.05 19 297320 197 90330911
Alveolitis 44.11 9.05 52 297287 2969 90328139
Hypertension 44.03 9.05 1878 295461 455654 89875454
Blepharospasm 43.82 9.05 322 297017 55123 90275985
Pneumocystis jirovecii infection 43.69 9.05 42 297297 1894 90329214
Candida sepsis 43.37 9.05 39 297300 1614 90329494
Pancytopenia 43.23 9.05 593 296746 119670 90211438
Gait disturbance 43.22 9.05 598 296741 259898 90071210
Central nervous system infection 43.09 9.05 30 297309 851 90330257
Post cholecystectomy syndrome 43.09 9.05 30 297309 851 90330257
Hepatitis B 42.98 9.05 63 297276 4456 90326652
Incorrect dose administered 42.94 9.05 125 297214 78805 90252303
Breast cancer stage II 42.75 9.05 32 297307 35302 90295806
Liver function test increased 42.63 9.05 446 296893 84409 90246699
Mycoplasma infection 42.57 9.05 30 297309 868 90330240
Urinary tract candidiasis 42.48 9.05 28 297311 724 90330384
Scedosporium infection 42.45 9.05 29 297310 797 90330311
Poisoning deliberate 42.42 9.05 3 297336 16483 90314625
Foot deformity 42.40 9.05 82 297257 59569 90271539
Substance-induced psychotic disorder 42.31 9.05 50 297289 2862 90328246
Myocardial infarction 42.31 9.05 191 297148 105781 90225327
Full blood count abnormal 41.94 9.05 35 297304 36562 90294546
Nail disorder 41.64 9.05 334 297005 58733 90272375
CSF oligoclonal band present 41.59 9.05 23 297316 428 90330680
Focal segmental glomerulosclerosis 41.48 9.05 40 297299 1811 90329297
Dyspnoea 41.44 9.05 2417 294922 878538 89452570
Necrotising herpetic retinopathy 41.38 9.05 16 297323 123 90330985
Muscular weakness 41.38 9.05 928 296411 205738 90125370
Dysphagia 41.33 9.05 556 296783 111722 90219386
Segmental diverticular colitis 41.27 9.05 17 297322 157 90330951
Status epilepticus 41.16 9.05 146 297193 18728 90312380
General physical health deterioration 41.14 9.05 870 296469 354245 89976863
Viraemia 41.09 9.05 38 297301 1631 90329477
Dizziness 41.05 9.05 1550 295789 587734 89743374
Product use issue 40.98 9.05 799 296540 329120 90001988
Multiple sclerosis relapse 40.90 9.05 303 297036 52002 90279106
Partial seizures 40.75 9.05 80 297259 7180 90323928
Chronic allograft nephropathy 40.63 9.05 28 297311 781 90330327
Obstructive airways disorder 40.55 9.05 17 297322 25852 90305256
Gastrointestinal mucormycosis 40.35 9.05 20 297319 294 90330814
Pedal pulse abnormal 40.31 9.05 18 297321 206 90330902
Immune reconstitution inflammatory syndrome 40.19 9.05 78 297261 6941 90324167
International normalised ratio increased 40.15 9.05 58 297281 47258 90283850
Atypical haemolytic uraemic syndrome 39.92 9.05 30 297309 961 90330147
Adrenal insufficiency 39.81 9.05 199 297140 29722 90301386
Adverse reaction 39.80 9.05 198 297141 29514 90301594
Chronic graft versus host disease 39.79 9.05 58 297281 4081 90327027
Listeriosis 39.69 9.05 38 297301 1705 90329403
Device malfunction 39.54 9.05 10 297329 20967 90310141
Respiratory rate increased 39.49 9.05 129 297210 15872 90315236
Device issue 39.42 9.05 24 297315 29513 90301595
Influenza 38.97 9.05 658 296681 138606 90192502
Toxoplasmosis 38.92 9.05 38 297301 1747 90329361
Central nervous system viral infection 38.91 9.05 16 297323 147 90330961
Bacterial sepsis 38.60 9.05 63 297276 4892 90326216
Pneumonia acinetobacter 38.47 9.05 14 297325 89 90331019
Hepatic enzyme increased 38.30 9.05 896 296443 359840 89971268
Steroid dependence 38.12 9.05 42 297297 2227 90328881
Device difficult to use 37.94 9.05 6 297333 17519 90313589
Sensory loss 37.87 9.05 138 297201 17937 90313171
Central nervous system lymphoma 37.80 9.05 40 297299 2025 90329083
Optic neuritis 37.63 9.05 92 297247 9586 90321522
Pruritus 37.57 9.05 1425 295914 540100 89791008
Diffuse alveolar damage 37.26 9.05 30 297309 1065 90330043
Cytomegalovirus enteritis 37.15 9.05 20 297319 352 90330756
Feeding intolerance 37.12 9.05 29 297310 985 90330123
Hyponatraemia 36.99 9.05 271 297068 133267 90197841
Immunosuppression 36.96 9.05 105 297234 11972 90319136
Multiple-drug resistance 36.95 9.05 80 297259 7696 90323412
Blood thyroid stimulating hormone decreased 36.87 9.05 67 297272 5673 90325435
Trichodysplasia spinulosa 36.85 9.05 25 297314 679 90330429
Liver injury 36.59 9.05 370 296969 170197 90160911
Throat tightness 36.37 9.05 192 297147 29292 90301816
Loss of personal independence in daily activities 36.37 9.05 279 297060 135826 90195282
Rheumatoid factor increased 36.03 9.05 42 297297 2369 90328739
Rhabdomyolysis 35.96 9.05 71 297268 51185 90279923
Lupus-like syndrome 35.72 9.05 66 297273 48780 90282328
Diffuse large B-cell lymphoma 35.57 9.05 84 297255 8561 90322547
Febrile bone marrow aplasia 35.17 9.05 90 297249 9648 90321460
Body temperature decreased 35.00 9.05 163 297176 23653 90307455
Cytomegalovirus gastrointestinal infection 34.97 9.05 20 297319 398 90330710
Loss of consciousness 34.93 9.05 293 297046 139945 90191163
Injection site pruritus 34.89 9.05 78 297261 53756 90277352
Infection 34.74 9.05 913 296426 361181 89969927
Red blood cell sedimentation rate abnormal 34.70 9.05 18 297321 24186 90306922
Female genital tract fistula 34.69 9.05 8 297331 17860 90313248
Joint stiffness 34.66 9.05 135 297204 77907 90253201
Calcium ionised decreased 34.57 9.05 19 297320 349 90330759
Pyomyositis 34.31 9.05 20 297319 413 90330695
Alternaria infection 34.19 9.05 19 297320 357 90330751
C-reactive protein abnormal 34.15 9.05 261 297078 127168 90203940
Quadriparesis 34.15 9.05 42 297297 2507 90328601
Meningoencephalitis viral 34.14 9.05 19 297320 358 90330750
Bacterial infection 34.12 9.05 160 297179 23284 90307824
Sedation complication 34.09 9.05 7 297332 16937 90314171
Transplant failure 34.04 9.05 37 297302 1932 90329176
Chronic graft versus host disease in skin 34.01 9.05 30 297309 1210 90329898
Mobility decreased 34.00 9.05 598 296741 250136 90080972
Product storage error 33.88 9.05 12 297327 20229 90310879
Lung abscess 33.83 9.05 39 297300 2174 90328934
Acute respiratory failure 33.77 9.05 249 297090 42669 90288439
Joint dislocation 33.71 9.05 59 297280 44523 90286585
Pulmonary vasculitis 33.62 9.05 16 297323 214 90330894
Exposure during pregnancy 33.59 9.05 1022 296317 237388 90093720
Disability 33.55 9.05 51 297288 40694 90290414
Scleroderma renal crisis 33.52 9.05 20 297319 432 90330676
Nitrite urine present 33.45 9.05 28 297311 1051 90330057
Large intestine perforation 33.27 9.05 88 297251 9624 90321484
Hemiparesis 33.15 9.05 198 297141 31621 90299487
Hyperglycaemia 33.14 9.05 283 297056 50687 90280421
West Nile viral infection 33.02 9.05 21 297318 510 90330598
Fungal skin infection 32.94 9.05 61 297278 5240 90325868
Swollen tongue 32.81 9.05 63 297276 45893 90285215
Poor venous access 32.74 9.05 139 297200 19388 90311720
Human bocavirus infection 32.72 9.05 20 297319 452 90330656
Temperature intolerance 32.44 9.05 100 297239 11930 90319178
Shock haemorrhagic 32.29 9.05 101 297238 12144 90318964
Dermatomyositis 32.07 9.05 47 297292 3323 90327785
Bacillus infection 32.06 9.05 26 297313 933 90330175
Cytomegalovirus enterocolitis 32.00 9.05 25 297314 849 90330259
Neuropsychiatric lupus 31.83 9.05 15 297324 196 90330912
Blood pressure systolic decreased 31.76 9.05 84 297255 9186 90321922
Cervicitis 31.73 9.05 21 297318 547 90330561
Secondary immunodeficiency 31.71 9.05 37 297302 2089 90329019
Hepatosplenomegaly 31.63 9.05 44 297295 2965 90328143
Mycobacterium abscessus infection 31.48 9.05 27 297312 1048 90330060
Hypofibrinogenaemia 31.44 9.05 30 297309 1340 90329768
Urinary tract infection bacterial 31.41 9.05 66 297273 6219 90324889
Malacoplakia vesicae 31.19 9.05 11 297328 63 90331045
Neuromyelitis optica spectrum disorder 31.15 9.05 31 297308 1459 90329649
Joint swelling 31.12 9.05 1342 295997 501958 89829150
Aspartate aminotransferase 31.01 9.05 23 297316 722 90330386
Full blood count decreased 30.92 9.05 31 297308 29658 90301450
Disseminated varicella zoster vaccine virus infection 30.90 9.05 11 297328 65 90331043
Osteomyelitis fungal 30.88 9.05 10 297329 42 90331066
Oral herpes 30.80 9.05 202 297137 33322 90297786
Mycoplasma test positive 30.74 9.05 13 297326 129 90330979
Malaise 30.57 9.05 1591 295748 584395 89746713
Peritonitis 30.55 9.05 137 297202 19568 90311540
Aphthous ulcer 30.51 9.05 125 297214 17162 90313946
Dry skin 30.42 9.05 167 297172 87906 90243202
Hepatic infarction 30.41 9.05 22 297317 664 90330444
Renal tubular atrophy 30.40 9.05 25 297314 915 90330193
Foetal growth restriction 30.13 9.05 83 297256 9297 90321811
Bronchiolitis obliterans syndrome 30.00 9.05 18 297321 393 90330715
Oropharyngeal pain 29.98 9.05 538 296801 114649 90216459
Growth retardation 29.94 9.05 33 297306 1750 90329358
Retinitis 29.90 9.05 50 297289 38408 90292700
Corynebacterium infection 29.76 9.05 25 297314 943 90330165
B-lymphocyte count decreased 29.68 9.05 30 297309 1439 90329669
Low birth weight baby 29.65 9.05 83 297256 9384 90321724
Emphysematous pyelonephritis 29.61 9.05 17 297322 341 90330767
Injury 29.60 9.05 462 296877 196887 90134221
Haemolytic anaemia 29.49 9.05 95 297244 11602 90319506
Encephalitis cytomegalovirus 29.40 9.05 22 297317 700 90330408
Pathogen resistance 29.30 9.05 75 297264 8040 90323068
Vesicoureteric reflux 29.21 9.05 16 297323 292 90330816
Visceral leishmaniasis 29.19 9.05 21 297318 628 90330480
Secondary adrenocortical insufficiency 29.14 9.05 37 297302 2281 90328827
Tuberculosis 29.04 9.05 99 297240 12450 90318658
Cutaneous lupus erythematosus 28.98 9.05 43 297296 3075 90328033
Suicidal ideation 28.95 9.05 134 297205 73721 90257387
SARS-CoV-2 viraemia 28.75 9.05 9 297330 33 90331075
Smear cervix abnormal 28.72 9.05 43 297296 3099 90328009
Seronegative arthritis 28.55 9.05 12 297327 18222 90312886
Myelopathy 28.49 9.05 45 297294 3399 90327709
Thyroxine free increased 28.47 9.05 25 297314 1002 90330106
Hypertransaminasaemia 28.38 9.05 115 297224 15710 90315398
Therapy non-responder 28.34 9.05 617 296722 136087 90195021
Unresponsive to stimuli 28.33 9.05 51 297288 38070 90293038
Meningoencephalitis bacterial 28.27 9.05 15 297324 256 90330852
Laryngeal stenosis 28.26 9.05 28 297311 1311 90329797
Mitochondrial DNA mutation 28.20 9.05 18 297321 440 90330668
Procedural pain 28.20 9.05 41 297298 33319 90297789
Graft loss 28.16 9.05 18 297321 441 90330667
Vaginal flatulence 28.11 9.05 4 297335 12634 90318474
Renal vein thrombosis 28.07 9.05 20 297319 589 90330519
Normal newborn 28.04 9.05 151 297188 23211 90307897
Diabetes mellitus 28.02 9.05 331 297008 64544 90266564
Lip pruritus 27.89 9.05 28 297311 1332 90329776
Motor dysfunction 27.81 9.05 131 297208 19099 90312009
Red blood cells urine 27.79 9.05 19 297320 523 90330585
Arterial occlusive disease 27.76 9.05 97 297242 12349 90318759
Glomerular filtration rate increased 27.69 9.05 34 297305 2026 90329082
Necrotising retinitis 27.57 9.05 19 297320 530 90330578
Aplastic anaemia 27.54 9.05 101 297238 13168 90317940
Microangiopathy 27.53 9.05 31 297308 1684 90329424
Chronic graft versus host disease in liver 27.47 9.05 16 297323 330 90330778
Type 2 diabetes mellitus 27.46 9.05 485 296854 202759 90128349
Ureteric stenosis 27.46 9.05 21 297318 691 90330417
Acarodermatitis 27.44 9.05 28 297311 1358 90329750
Type I hypersensitivity 27.33 9.05 49 297290 4106 90327002
Torsade de pointes 27.18 9.05 8 297331 15174 90315934
Pulmonary haemorrhage 26.83 9.05 72 297267 7941 90323167
Therapy interrupted 26.79 9.05 80 297259 50028 90281080
Rubella antibody positive 26.79 9.05 10 297329 69 90331039
Hypophagia 26.78 9.05 48 297291 35889 90295219
Peptostreptococcus infection 26.66 9.05 11 297328 102 90331006
Mycotic endophthalmitis 26.60 9.05 13 297326 185 90330923
Rhodococcus infection 26.52 9.05 12 297327 142 90330966
Schizophrenia 26.45 9.05 8 297331 14906 90316202
Disease progression 26.41 9.05 687 296652 155928 90175180
Lethargy 26.29 9.05 112 297227 63027 90268081
Unevaluable event 26.24 9.05 92 297247 54756 90276352
Human polyomavirus infection 26.23 9.05 17 297322 427 90330681
Serum sickness 26.20 9.05 44 297295 3498 90327610
Blood cholesterol increased 26.04 9.05 503 296836 207509 90123599
Disseminated cryptococcosis 26.02 9.05 21 297318 748 90330360
Walking aid user 25.94 9.05 48 297291 35458 90295650
Q fever 25.94 9.05 12 297327 150 90330958
Hypertrichosis 25.93 9.05 28 297311 1451 90329657
Paraesthesia ear 25.78 9.05 17 297322 440 90330668
Plasma cell myeloma 25.77 9.05 60 297279 40768 90290340
Pyelonephritis 25.74 9.05 138 297201 21178 90309930
Pneumonia 25.61 9.05 2428 294911 635631 89695477
Aspergillosis oral 25.60 9.05 9 297330 51 90331057
Central obesity 25.58 9.05 27 297312 1363 90329745
Klebsiella test positive 25.56 9.05 28 297311 1475 90329633
Quadriplegia 25.54 9.05 34 297305 2197 90328911
Injection site mass 25.47 9.05 21 297318 22069 90309039
Tardive dyskinesia 25.42 9.05 3 297336 10927 90320181
Asthma 25.26 9.05 603 296736 241557 90089551
Specific gravity urine decreased 25.18 9.05 21 297318 784 90330324
Varicella 25.07 9.05 35 297304 2367 90328741
Osteonecrosis of jaw 25.06 9.05 57 297282 39046 90292062
Interleukin level increased 25.04 9.05 20 297319 702 90330406
Obliterative bronchiolitis 24.95 9.05 37 297302 2644 90328464
Haemodynamic instability 24.91 9.05 90 297249 11649 90319459
IgA nephropathy 24.86 9.05 22 297317 891 90330217
Visual impairment 24.84 9.05 296 297043 132069 90199039
Blood potassium increased 24.83 9.05 19 297320 20730 90310378
Prescribed overdose 24.74 9.05 203 297136 97422 90233686
Herpes simplex reactivation 24.70 9.05 23 297316 996 90330112
Factor XIII deficiency 24.69 9.05 10 297329 88 90331020
Blood parathyroid hormone decreased 24.67 9.05 5 297334 12211 90318897
Granuloma skin 24.67 9.05 3 297336 10677 90320431
Anti-thyroid antibody positive 24.58 9.05 17 297322 477 90330631
Cerebellar stroke 24.47 9.05 16 297323 408 90330700
Malignant catatonia 24.45 9.05 13 297326 223 90330885
Sleep disorder 24.44 9.05 480 296859 197550 90133558
Vitamin B12 increased 24.32 9.05 30 297309 1796 90329312
Myelitis 24.30 9.05 32 297307 2046 90329062
Dyschromatopsia 24.21 9.05 20 297319 737 90330371
Disseminated cytomegaloviral infection 24.11 9.05 14 297325 287 90330821
Haemoglobin urine 24.10 9.05 11 297328 133 90330975
Coronary artery disease 24.08 9.05 46 297293 33577 90297531
Cerebral artery stenosis 24.05 9.05 18 297321 573 90330535
Adjustment disorder 24.03 9.05 78 297261 9564 90321544
Thunderclap headache 24.00 9.05 15 297324 353 90330755
CSF measles antibody positive 24.00 9.05 9 297330 63 90331045
Carotid artery thrombosis 23.98 9.05 75 297264 9017 90322091
Hepatocellular injury 23.93 9.05 170 297169 28788 90302320
Malacoplakia gastrointestinal 23.88 9.05 9 297330 64 90331044
Injection site haemorrhage 23.74 9.05 35 297304 28283 90302825
Congenital cytomegalovirus infection 23.67 9.05 11 297328 139 90330969
Haemolytic uraemic syndrome 23.63 9.05 37 297302 2774 90328334
Blood immunoglobulin G decreased 23.62 9.05 42 297297 3496 90327612
Electrocardiogram QT prolonged 23.61 9.05 140 297199 72316 90258792
CSF protein increased 23.55 9.05 20 297319 766 90330342
Hyperammonaemia 23.54 9.05 60 297279 6415 90324693
Blood brain barrier defect 23.53 9.05 11 297328 141 90330967
Citrobacter infection 23.44 9.05 19 297320 681 90330427
Gangrene 23.43 9.05 94 297245 12782 90318326
Meningomyelitis herpes 23.42 9.05 8 297331 41 90331067
Haemostasis 23.42 9.05 15 297324 369 90330739
Neurologic neglect syndrome 23.36 9.05 73 297266 8774 90322334
Renal graft infection 23.35 9.05 15 297324 371 90330737
Therapy cessation 23.30 9.05 53 297286 36308 90294800
Papilloma viral infection 23.29 9.05 29 297310 1753 90329355
Necrosis ischaemic 23.24 9.05 22 297317 973 90330135
Back disorder 23.18 9.05 30 297309 25601 90305507
Underdose 23.00 9.05 95 297244 53922 90277186
Pneumatosis 22.94 9.05 16 297323 455 90330653
Graft versus host disease in lung 22.94 9.05 17 297322 533 90330575
Flatulence 22.88 9.05 65 297274 41302 90289806
Hypokalaemia 22.81 9.05 298 297041 130818 90200290
Kaposi's sarcoma 22.80 9.05 11 297328 152 90330956
Jaundice cholestatic 22.76 9.05 3 297336 10040 90321068
Hepatic necrosis 22.73 9.05 59 297280 6379 90324729
Muir-Torre syndrome 22.72 9.05 7 297332 24 90331084
Gastropleural fistula 22.66 9.05 8 297331 46 90331062
Ulcer haemorrhage 22.59 9.05 32 297307 26289 90304819
Kidney fibrosis 22.49 9.05 32 297307 2202 90328906
Angiosarcoma metastatic 22.45 9.05 9 297330 77 90331031
Serum ferritin increased 22.42 9.05 64 297275 7317 90323791
Musculoskeletal stiffness 22.40 9.05 772 296567 295760 90035348
Genital herpes 22.31 9.05 31 297308 2087 90329021
Systemic inflammatory response syndrome 22.28 9.05 59 297280 6457 90324651
Clostridium difficile colitis 22.20 9.05 157 297182 26549 90304559
Choroiditis 22.20 9.05 13 297326 271 90330837
Ulcer 22.13 9.05 184 297155 32698 90298410
Urine leukocyte esterase 22.11 9.05 11 297328 163 90330945
Parvovirus infection 22.11 9.05 16 297323 483 90330625
Needle issue 22.09 9.05 9 297330 13925 90317183
Suspected COVID-19 22.09 9.05 35 297304 2651 90328457
Linear IgA disease 22.06 9.05 32 297307 2242 90328866
Birdshot chorioretinopathy 22.05 9.05 9 297330 81 90331027
Band sensation 21.97 9.05 23 297316 1150 90329958
Hypoproteinaemia 21.89 9.05 38 297301 3104 90328004
Monoparesis 21.85 9.05 30 297309 1997 90329111
Lip swelling 21.85 9.05 60 297279 38550 90292558
Fungal infection 21.79 9.05 225 297114 42436 90288672
Bacterial vulvovaginitis 21.73 9.05 20 297319 853 90330255
Atrial fibrillation 21.68 9.05 308 297031 133303 90197805
Foetal death 21.62 9.05 129 297210 20594 90310514
Fungal endocarditis 21.55 9.05 14 297325 353 90330755
Liver abscess 21.44 9.05 40 297299 3456 90327652
Ultrasound ovary abnormal 21.40 9.05 9 297330 88 90331020
Fungaemia 21.39 9.05 39 297300 3311 90327797
Sense of oppression 21.38 9.05 22 297317 1078 90330030
Aplasia 21.23 9.05 43 297296 3948 90327160
Pneumonia adenoviral 21.15 9.05 12 297327 235 90330873
Passenger lymphocyte syndrome 21.13 9.05 9 297330 91 90331017
Interleukin-2 receptor increased 21.00 9.05 10 297329 134 90330974
General symptom 20.89 9.05 11 297328 14657 90316451
Ureteral disorder 20.87 9.05 14 297325 373 90330735
Infusion site reaction 20.82 9.05 120 297219 18919 90312189
Rash pruritic 20.81 9.05 171 297168 82043 90249065
Engraftment syndrome 20.81 9.05 18 297321 707 90330401
Hypertriglyceridaemia 20.74 9.05 65 297274 7824 90323284
Natural killer-cell leukaemia 20.71 9.05 9 297330 96 90331012
Drug tolerance 20.69 9.05 17 297322 17899 90313209
Bone pain 20.60 9.05 119 297220 61864 90269244
Actinomycotic sepsis 20.58 9.05 12 297327 248 90330860
Hydronephrosis 20.57 9.05 88 297251 12314 90318794
Creatinine renal clearance decreased 20.54 9.05 19 297320 18880 90312228
Pyelonephritis acute 20.45 9.05 51 297288 5381 90325727
Cellulitis staphylococcal 20.42 9.05 20 297319 923 90330185
Syncope 20.42 9.05 309 297030 132354 90198754
Cryptococcal cutaneous infection 20.39 9.05 9 297330 100 90331008
Chronic sinusitis 20.37 9.05 29 297310 23773 90307335
Phaeohyphomycosis 20.30 9.05 15 297324 468 90330640
Red blood cell count increased 20.27 9.05 40 297299 3603 90327505
Tuberculosis gastrointestinal 20.27 9.05 14 297325 392 90330716
Monocyte count decreased 20.26 9.05 33 297306 2558 90328550
Renal tubular necrosis 20.21 9.05 98 297241 14457 90316651
Myasthenia gravis crisis 20.17 9.05 21 297318 1043 90330065
Cytomegalovirus hepatitis 20.17 9.05 14 297325 395 90330713
Respiratory distress 20.17 9.05 206 297133 38740 90292368
Haemorrhagic varicella syndrome 20.17 9.05 5 297334 5 90331103
Metastases to liver 20.12 9.05 40 297299 28767 90302341
Butterfly rash 20.11 9.05 30 297309 2155 90328953
Sinus polyp degeneration 20.10 9.05 8 297331 67 90331041
Product prescribing error 20.09 9.05 43 297296 30102 90301006
Cerebral venous thrombosis 20.07 9.05 31 297308 2297 90328811
Locked-in syndrome 20.05 9.05 15 297324 477 90330631
Infectious pleural effusion 20.01 9.05 28 297311 1897 90329211
Joint tuberculosis 19.94 9.05 10 297329 151 90330957
Pharyngeal disorder 19.93 9.05 32 297307 2451 90328657
Gamma-glutamyltransferase increased 19.78 9.05 201 297138 37751 90293357
Leukoencephalopathy 19.67 9.05 47 297292 4826 90326282
Hyperhidrosis 19.64 9.05 586 296753 135719 90195389
Porphyria acute 19.62 9.05 18 297321 17957 90313151
Transient ischaemic attack 19.61 9.05 74 297265 43102 90288006
Enterococcus test positive 19.61 9.05 23 297316 1306 90329802
Hairy cell leukaemia 19.61 9.05 6 297333 20 90331088
Meningitis cryptococcal 19.56 9.05 27 297312 1806 90329302
Hypercalcaemia 19.53 9.05 53 297286 34187 90296921
Sneezing 19.50 9.05 166 297173 29703 90301405
Cardiac sarcoidosis 19.49 9.05 9 297330 112 90330996
Spinal disorder 19.48 9.05 83 297256 11596 90319512
Complication associated with device 19.47 9.05 21 297318 19428 90311680
Enterocolitis viral 19.46 9.05 13 297326 344 90330764
Bone marrow failure 19.44 9.05 176 297163 32045 90299063
Chronic graft versus host disease in eye 19.41 9.05 11 297328 215 90330893
Aspergilloma 19.41 9.05 12 297327 277 90330831
Dystonia 19.38 9.05 16 297323 16803 90314305
Cryptococcal meningoencephalitis 19.37 9.05 10 297329 161 90330947
Band neutrophil percentage increased 19.36 9.05 11 297328 216 90330892
Product dispensing error 19.34 9.05 8 297331 12265 90318843
Glomerulosclerosis 19.31 9.05 15 297324 505 90330603
Dengue fever 19.29 9.05 19 297320 883 90330225
Intracranial infection 19.27 9.05 11 297328 218 90330890
Donor specific antibody present 19.23 9.05 11 297328 219 90330889
Infective pulmonary exacerbation of cystic fibrosis 19.18 9.05 5 297334 10274 90320834
Lichen sclerosus 19.14 9.05 23 297316 1340 90329768
Acute oesophageal mucosal lesion 19.14 9.05 9 297330 117 90330991
Arterial intramural haematoma 19.10 9.05 10 297329 166 90330942
Deafness congenital 19.07 9.05 9 297330 118 90330990
Rhinocerebral mucormycosis 19.05 9.05 18 297321 794 90330314
Bronchial anastomosis complication 19.04 9.05 8 297331 78 90331030
Complications of transplanted lung 18.98 9.05 13 297326 359 90330749
Anal erythema 18.96 9.05 12 297327 289 90330819
Blood immunoglobulin M decreased 18.95 9.05 23 297316 1354 90329754
Chronic graft versus host disease oral 18.92 9.05 11 297328 226 90330882
Blood lactate dehydrogenase decreased 18.88 9.05 11 297328 227 90330881
Laboratory test abnormal 18.84 9.05 72 297267 41782 90289326
Gastrointestinal disorder 18.76 9.05 671 296668 256016 90075092
Urine oxalate increased 18.71 9.05 11 297328 231 90330877
Hallucination 18.67 9.05 133 297206 65826 90265282
Blastomycosis 18.67 9.05 14 297325 447 90330661
Breast cancer female 18.64 9.05 13 297326 14873 90316235
Disseminated varicella zoster virus infection 18.59 9.05 14 297325 450 90330658
Inflammatory pain 18.58 9.05 20 297319 1033 90330075
Injection site warmth 18.57 9.05 18 297321 17497 90313611
Cytokine release syndrome 18.54 9.05 156 297183 27817 90303291
Vascular device infection 18.50 9.05 8 297331 11944 90319164
Hepatic cyst infection 18.48 9.05 9 297330 127 90330981
Hepatitis toxic 18.48 9.05 39 297300 3686 90327422
Allergy test positive 18.48 9.05 17 297322 725 90330383
Hemiplegia 18.42 9.05 103 297236 16057 90315051
Autoimmune hepatitis 18.39 9.05 75 297264 10276 90320832
Device leakage 18.38 9.05 5 297334 9986 90321122
Sputum discoloured 18.30 9.05 24 297315 20367 90310741
Reticulocytosis 18.26 9.05 11 297328 242 90330866
Hypertensive encephalopathy 18.22 9.05 17 297322 738 90330370
Escherichia sepsis 18.22 9.05 51 297288 5765 90325343
Asymptomatic bacteriuria 18.22 9.05 12 297327 310 90330798
Sinus congestion 18.21 9.05 153 297186 27271 90303837
Mouth ulceration 18.18 9.05 206 297133 39768 90291340
Bursitis 18.16 9.05 563 296776 131091 90200017
Mucocutaneous leishmaniasis 18.09 9.05 13 297326 388 90330720
Dural arteriovenous fistula 18.02 9.05 6 297333 28 90331080
Neutrophil count decreased 18.01 9.05 149 297190 71383 90259725
Pneumonia lipoid 18.00 9.05 9 297330 135 90330973
Monocyte percentage increased 17.98 9.05 21 297318 1187 90329921
Pulmonary hypertension 17.97 9.05 75 297264 42448 90288660
Pyuria 17.96 9.05 28 297311 2091 90329017
Focal nodular hyperplasia 17.90 9.05 17 297322 755 90330353
Band neutrophil count increased 17.86 9.05 13 297326 396 90330712
Steroid withdrawal syndrome 17.84 9.05 16 297323 660 90330448
Skin striae 17.84 9.05 24 297315 1567 90329541
Pulmonary interstitial emphysema syndrome 17.84 9.05 5 297334 11 90331097
Pseudomonal bacteraemia 17.82 9.05 27 297312 1967 90329141
Autoimmune thyroiditis 17.80 9.05 51 297288 5842 90325266
Anti-neutrophil cytoplasmic antibody positive vasculitis 17.75 9.05 40 297299 3953 90327155
Moyamoya disease 17.73 9.05 8 297331 94 90331014
Dry throat 17.72 9.05 62 297277 7898 90323210
Glomerulonephritis chronic 17.71 9.05 9 297330 140 90330968
Enterovirus infection 17.70 9.05 23 297316 1451 90329657
Clubbing 17.66 9.05 14 297325 486 90330622
Herpes simplex oesophagitis 17.62 9.05 10 297329 196 90330912
Listeria encephalitis 17.56 9.05 11 297328 260 90330848
Japanese spotted fever 17.52 9.05 6 297333 31 90331077
Eye infection toxoplasmal 17.50 9.05 13 297326 409 90330699
Grip strength 17.43 9.05 4 297335 8961 90322147
Biloma 17.43 9.05 8 297331 98 90331010
Urinary tract infection 17.42 9.05 1195 296144 304437 90026671
Faecal volume decreased 17.37 9.05 11 297328 265 90330843
Product preparation error 17.32 9.05 6 297333 10255 90320853
Cerebrovascular accident 17.25 9.05 293 297046 123240 90207868
Cancer in remission 17.25 9.05 7 297332 62 90331046
Tendon rupture 17.24 9.05 68 297271 9175 90321933
Cytopenia 17.17 9.05 107 297232 17342 90313766
Blood gases abnormal 17.14 9.05 18 297321 903 90330205
Candida pneumonia 17.14 9.05 10 297329 207 90330901
Nightmare 17.12 9.05 28 297311 21697 90309411
Parainfluenzae virus infection 17.10 9.05 32 297307 2771 90328337
Mean cell haemoglobin decreased 16.93 9.05 49 297290 5646 90325462
Coronavirus infection 16.93 9.05 48 297291 5467 90325641
Glomerulonephritis membranous 16.91 9.05 16 297323 707 90330401
Pancreatitis 16.88 9.05 147 297192 69679 90261429
Musculoskeletal pain 16.88 9.05 430 296909 170821 90160287
Meningitis staphylococcal 16.81 9.05 8 297331 107 90331001
Chorioretinitis 16.81 9.05 17 297322 816 90330292
Nerve compression 16.78 9.05 74 297265 10492 90320616
Dementia 16.78 9.05 33 297306 23828 90307280
Parkinsonism 16.68 9.05 13 297326 14052 90317056
Bronchostenosis 16.64 9.05 14 297325 529 90330579
Labelled drug-drug interaction medication error 16.64 9.05 14 297325 14568 90316540
Tubulointerstitial nephritis 16.62 9.05 141 297198 25202 90305906
Microscopic polyangiitis 16.56 9.05 10 297329 221 90330887
Herpes zoster infection neurological 16.56 9.05 14 297325 533 90330575
Throat clearing 16.51 9.05 38 297301 3809 90327299
Germ cell cancer 16.51 9.05 7 297332 70 90331038
Feeling hot 16.46 9.05 353 296986 77655 90253453
Hyperferritinaemia 16.45 9.05 12 297327 367 90330741
Serratia infection 16.38 9.05 19 297320 1066 90330042
Injection site urticaria 16.37 9.05 21 297318 17990 90313118
Panniculitis 16.35 9.05 14 297325 14444 90316664
Thrombocytopenic purpura 16.35 9.05 25 297314 1836 90329272
Dyskinesia 16.35 9.05 63 297276 36471 90294637
Propofol infusion syndrome 16.25 9.05 21 297318 1318 90329790
Oral pain 16.19 9.05 54 297285 32629 90298479
Complication of device insertion 16.13 9.05 7 297332 10429 90320679
Transient hypogammaglobulinaemia of infancy 16.12 9.05 6 297333 41 90331067
Hypotension 16.12 9.05 1258 296081 324139 90006969
Impaired work ability 16.09 9.05 24 297315 19302 90311806
Leukocytosis 16.09 9.05 164 297175 30826 90300282
Renal artery stenosis 16.05 9.05 27 297312 2150 90328958
Lepromatous leprosy 16.04 9.05 5 297334 18 90331090
Biliary anastomosis complication 16.00 9.05 6 297333 42 90331066
Fracture 15.99 9.05 30 297309 22046 90309062
Toxic epidermal necrolysis 15.88 9.05 170 297169 32358 90298750
Taste disorder 15.84 9.05 287 297052 61259 90269849
Organic brain syndrome 15.83 9.05 10 297329 240 90330868
Blood lactate dehydrogenase increased 15.82 9.05 142 297197 25790 90305318
Oropharyngeal plaque 15.80 9.05 11 297328 312 90330796
Tri-iodothyronine free decreased 15.79 9.05 12 297327 391 90330717
Cystitis 15.75 9.05 307 297032 66411 90264697
Klebsiella sepsis 15.75 9.05 24 297315 1757 90329351
Mycobacterial infection 15.75 9.05 27 297312 2183 90328925
Poisoning 15.72 9.05 16 297323 15201 90315907
Ill-defined disorder 15.71 9.05 474 296865 184417 90146691
Diabetic macroangiopathy 15.71 9.05 8 297331 125 90330983
Epiglottic erythema 15.68 9.05 7 297332 80 90331028
Encephalitis Japanese B 15.65 9.05 6 297333 45 90331063
Aortitis salmonella 15.63 9.05 5 297334 20 90331088
Delayed engraftment 15.59 9.05 8 297331 127 90330981
Wound infection bacterial 15.59 9.05 15 297324 677 90330431
Pyrexia 15.59 9.05 2431 294908 658054 89673054
Psychiatric decompensation 15.54 9.05 25 297314 1918 90329190
Epidural lipomatosis 15.50 9.05 10 297329 249 90330859
Fracture pain 15.48 9.05 19 297320 1132 90329976
Memory impairment 15.47 9.05 511 296828 196733 90134375
Condition aggravated 15.47 9.05 2204 295135 593341 89737767
Acute disseminated encephalomyelitis 15.47 9.05 10 297329 250 90330858
Skin infection 15.42 9.05 106 297233 17758 90313350
Myocarditis infectious 15.42 9.05 6 297333 47 90331061
Orbital apex syndrome 15.42 9.05 6 297333 47 90331061
Extremity necrosis 15.41 9.05 25 297314 1932 90329176
Osteogenesis imperfecta 15.40 9.05 17 297322 903 90330205
Device breakage 15.40 9.05 14 297325 14030 90317078
Anxiety 15.38 9.05 845 296494 308927 90022181
Blood loss anaemia 15.36 9.05 7 297332 10133 90320975
Product complaint 15.36 9.05 13 297326 13487 90317621
Meningitis listeria 15.32 9.05 15 297324 692 90330416
Meningitis aseptic 15.29 9.05 53 297286 6720 90324388
Transplant dysfunction 15.27 9.05 45 297294 5237 90325871
Pneumonia pseudomonal 15.27 9.05 33 297306 3170 90327938
Thyroid stimulating immunoglobulin increased 15.27 9.05 8 297331 133 90330975
Increased ventricular preload 15.26 9.05 5 297334 22 90331086
Rheumatoid factor 15.24 9.05 13 297326 501 90330607
Hepatitis C 15.22 9.05 47 297292 5613 90325495
Herpes zoster meningoencephalitis 15.17 9.05 12 297327 415 90330693
Parathyroid hyperplasia 15.16 9.05 8 297331 135 90330973
Mean cell haemoglobin concentration increased 15.14 9.05 14 297325 601 90330507
Excessive skin 15.11 9.05 8 297331 136 90330972
Myocardiac abscess 15.08 9.05 5 297334 23 90331085
Angiocentric lymphoma 15.07 9.05 15 297324 706 90330402
Impaired gastric emptying 14.99 9.05 12 297327 12797 90318311
Akathisia 14.98 9.05 9 297330 11150 90319958
Ovarian fibroma 14.95 9.05 7 297332 90 90331018
Hereditary angioedema 14.93 9.05 6 297333 9359 90321749
Seroconversion test positive 14.90 9.05 5 297334 24 90331084
Pseudoaldosteronism 14.90 9.05 8 297331 140 90330968
Benign mediastinal neoplasm 14.90 9.05 6 297333 52 90331056
Agranulocytosis 14.86 9.05 178 297161 34824 90296284
Refractory anaemia with an excess of blasts 14.79 9.05 12 297327 431 90330677
Blood creatinine decreased 14.73 9.05 51 297288 6464 90324644
Infected skin ulcer 14.69 9.05 29 297310 2613 90328495
Mycobacterium haemophilum infection 14.66 9.05 9 297330 205 90330903
Abdominal pain upper 14.63 9.05 918 296421 331756 89999352
Spinal cord infarction 14.62 9.05 11 297328 353 90330755
Plasmodium falciparum infection 14.60 9.05 6 297333 55 90331053
Infected varicose vein 14.58 9.05 5 297334 26 90331082
Right ventricle outflow tract obstruction 14.58 9.05 5 297334 26 90331082
Toxic neuropathy 14.52 9.05 13 297326 535 90330573
Mediastinal cyst 14.51 9.05 6 297333 56 90331052
Histoplasmosis 14.50 9.05 26 297313 2178 90328930
Eosinophil count abnormal 14.50 9.05 16 297323 850 90330258
Drug interaction 14.49 9.05 750 296589 275703 90055405
Muscle hypertrophy 14.49 9.05 7 297332 97 90331011
Nosocomial infection 14.47 9.05 24 297315 1889 90329219
Pneumonia cryptococcal 14.46 9.05 19 297320 1212 90329896
Pain in jaw 14.45 9.05 95 297244 47890 90283218
Radiculopathy 14.44 9.05 24 297315 18481 90312627
Renal haemorrhage 14.43 9.05 18 297321 1090 90330018
Breast cancer metastatic 14.43 9.05 17 297322 15115 90315993
Neurological decompensation 14.38 9.05 34 297305 3467 90327641
Mycobacterium chelonae infection 14.35 9.05 14 297325 643 90330465
Alveolar proteinosis 14.34 9.05 16 297323 860 90330248
Cerebral venous sinus thrombosis 14.34 9.05 27 297312 2349 90328759
Pyometra 14.30 9.05 7 297332 100 90331008
Nasal polyps 14.30 9.05 9 297330 10871 90320237
Joint noise 14.29 9.05 44 297295 5246 90325862
Body temperature increased 14.28 9.05 216 297123 44494 90286614
Lung neoplasm malignant 14.28 9.05 37 297302 24236 90306872
Subcutaneous drug absorption impaired 14.27 9.05 14 297325 13531 90317577
Otitis media 14.19 9.05 47 297292 5823 90325285
Metastases to bone 14.16 9.05 40 297299 25465 90305643
Hallucination, auditory 14.13 9.05 19 297320 15956 90315152
Premature baby 14.13 9.05 135 297204 24942 90306166
Periostitis 14.12 9.05 12 297327 460 90330648
Disseminated mucormycosis 14.10 9.05 14 297325 657 90330451
Nose deformity 14.10 9.05 9 297330 220 90330888
Joint range of motion decreased 14.07 9.05 338 297001 135305 90195803
Mean cell haemoglobin concentration decreased 14.04 9.05 39 297300 4389 90326719
Hydrocephalus 14.03 9.05 48 297291 6046 90325062
Breast cancer stage I 14.03 9.05 7 297332 9617 90321491
Venous thrombosis 13.99 9.05 45 297294 5492 90325616
Type IIb hyperlipidaemia 13.98 9.05 5 297334 30 90331078
Septic arthritis staphylococcal 13.94 9.05 13 297326 564 90330544
Escherichia bacteraemia 13.94 9.05 46 297293 5689 90325419
Creatinine urine decreased 13.87 9.05 10 297329 300 90330808
Multiple fractures 13.87 9.05 7 297332 9555 90321553
Measles 13.87 9.05 11 297328 382 90330726
Vascular rupture 13.87 9.05 23 297316 1810 90329298
Haemophilus infection 13.86 9.05 20 297319 1394 90329714
Osteomyelitis acute 13.85 9.05 10 297329 301 90330807
Rhinitis allergic 13.83 9.05 21 297318 16764 90314344
Immune effector cell-associated neurotoxicity syndrome 13.78 9.05 46 297293 5722 90325386
Capillaritis 13.78 9.05 8 297331 164 90330944
Cestode infection 13.76 9.05 10 297329 304 90330804
Congenital anomaly 13.76 9.05 49 297290 6298 90324810
Overdose 13.73 9.05 403 296936 157306 90173802
Bone giant cell tumour 13.73 9.05 6 297333 65 90331043
Chronic lymphocytic leukaemia recurrent 13.72 9.05 11 297328 388 90330720
Spinal cord paralysis 13.71 9.05 5 297334 32 90331076
Blood thyroid stimulating hormone increased 13.70 9.05 63 297276 9092 90322016
Paraparesis 13.70 9.05 30 297309 2908 90328200
Humoral immune defect 13.70 9.05 11 297328 389 90330719
Mental status changes 13.69 9.05 88 297251 44591 90286517
Gastrointestinal viral infection 13.66 9.05 20 297319 1413 90329695
Achromobacter infection 13.65 9.05 6 297333 66 90331042
Poikiloderma 13.65 9.05 10 297329 308 90330800
Injection site haematoma 13.64 9.05 3 297336 6919 90324189
Premenstrual syndrome 13.62 9.05 15 297324 795 90330313
Intestinal obstruction 13.60 9.05 69 297270 37062 90294046
Viral infection 13.59 9.05 201 297138 41213 90289895
Heliotrope rash 13.54 9.05 9 297330 236 90330872
Breast cancer 13.52 9.05 112 297227 53649 90277459
Insomnia 13.51 9.05 927 296412 332547 89998561
Neuropsychiatric syndrome 13.49 9.05 6 297333 68 90331040
Epstein-Barr virus associated lymphoma 13.47 9.05 14 297325 694 90330414
Globulins decreased 13.46 9.05 11 297328 399 90330709
Complications of transplanted liver 13.44 9.05 11 297328 400 90330708
Abscess 13.41 9.05 107 297232 18784 90312324
Adenoviral haemorrhagic cystitis 13.40 9.05 8 297331 173 90330935
Aeromonas infection 13.40 9.05 8 297331 173 90330935
Human herpesvirus 6 encephalitis 13.39 9.05 11 297328 402 90330706
Bone loss 13.37 9.05 33 297306 3459 90327649
Intestinal infarction 13.37 9.05 17 297322 1050 90330058
Encephalitis viral 13.36 9.05 23 297316 1866 90329242
Oesophageal candidiasis 13.36 9.05 51 297288 6778 90324330
Pneumonia fungal 13.34 9.05 52 297287 6979 90324129
Myelocyte count increased 13.32 9.05 11 297328 405 90330703
Vaginal haemorrhage 13.31 9.05 55 297284 31216 90299892
Respiratory tract oedema 13.24 9.05 14 297325 708 90330400
Acute myeloid leukaemia recurrent 13.20 9.05 24 297315 2033 90329075
Infusion site mobility decreased 13.18 9.05 6 297333 72 90331036
Sebaceous carcinoma 13.18 9.05 6 297333 72 90331036
Urinary tract infection enterococcal 13.17 9.05 30 297309 2986 90328122
Allergy to plants 13.17 9.05 15 297324 825 90330283
Herpes simplex encephalitis 13.16 9.05 11 297328 412 90330696
Drug level decreased 13.14 9.05 65 297274 9665 90321443
Hypomagnesaemia 13.11 9.05 66 297273 35522 90295586
Joint effusion 13.11 9.05 110 297229 19600 90311508
Varicose ulceration 13.10 9.05 12 297327 509 90330599
Blood uric acid increased 13.04 9.05 55 297284 7649 90323459
Body height decreased 13.00 9.05 12 297327 11937 90319171
Small intestine gangrene 12.98 9.05 5 297334 38 90331070
Laryngeal mass 12.98 9.05 5 297334 38 90331070
Paralysis 12.98 9.05 73 297266 11405 90319703
Shock 12.95 9.05 148 297191 28630 90302478
Microsporidia infection 12.89 9.05 10 297329 336 90330772
Noninfective encephalitis 12.88 9.05 12 297327 520 90330588
Heart rate irregular 12.87 9.05 129 297210 24139 90306969
Cells in urine 12.85 9.05 8 297331 187 90330921
Myelocyte percentage increased 12.85 9.05 8 297331 187 90330921
Central nervous system vasculitis 12.85 9.05 17 297322 1092 90330016
Cholecystitis acute 12.83 9.05 63 297276 9341 90321767
Bladder hypertrophy 12.82 9.05 12 297327 523 90330585
Peliosis hepatis 12.81 9.05 7 297332 127 90330981
Overlap syndrome 12.79 9.05 6 297333 8542 90322566
Vein rupture 12.78 9.05 21 297318 1640 90329468
Sleep disorder due to a general medical condition 12.76 9.05 90 297249 44648 90286460
Eastern Cooperative Oncology Group performance status 12.72 9.05 7 297332 129 90330979
Plasmapheresis 12.72 9.05 10 297329 343 90330765
Feeling cold 12.70 9.05 142 297197 27323 90303785
Erythrosis 12.69 9.05 6 297333 79 90331029
Disseminated blastomycosis 12.69 9.05 6 297333 79 90331029
Thrombotic thrombocytopenic purpura 12.68 9.05 36 297303 4102 90327006
Body temperature fluctuation 12.68 9.05 25 297314 2250 90328858
Swelling face 12.68 9.05 189 297150 81163 90249945
Lip dry 12.66 9.05 244 297095 100711 90230397
Mean cell volume decreased 12.66 9.05 38 297301 4468 90326640
Abnormal dreams 12.61 9.05 11 297328 11246 90319862
Aphasia 12.60 9.05 204 297135 42608 90288500
Urinoma 12.55 9.05 5 297334 42 90331066
Multisystem inflammatory syndrome in children 12.51 9.05 4 297335 16 90331092
Gastrointestinal pain 12.49 9.05 11 297328 11195 90319913
Feeling abnormal 12.48 9.05 436 296903 166799 90164309
Menstruation irregular 12.46 9.05 56 297283 8004 90323104
Histoplasmosis disseminated 12.46 9.05 25 297314 2280 90328828
Norovirus infection 12.45 9.05 22 297317 1822 90329286
Chromoblastomycosis 12.45 9.05 5 297334 43 90331065
Tuberculosis of central nervous system 12.45 9.05 10 297329 354 90330754
Haematoma muscle 12.40 9.05 22 297317 1828 90329280
Tooth deposit 12.40 9.05 9 297330 273 90330835
Colitis ulcerative 12.39 9.05 132 297207 60134 90270974
Superinfection bacterial 12.36 9.05 16 297323 1006 90330102
Coinfection 12.35 9.05 5 297334 44 90331064
Procalcitonin increased 12.34 9.05 20 297319 1544 90329564
Hyperpyrexia 12.31 9.05 39 297300 4722 90326386
Right ventricular failure 12.30 9.05 28 297311 19177 90311931
Diverticulum 12.22 9.05 13 297326 12100 90319008
Thrombosis 12.19 9.05 168 297171 73083 90258025
Dactylitis 12.17 9.05 34 297305 3839 90327269
Enterobacter pneumonia 12.15 9.05 5 297334 46 90331062
Diffuse large B-cell lymphoma stage III 12.15 9.05 5 297334 46 90331062
Stridor 12.15 9.05 39 297300 4754 90326354
Candida test positive 12.15 9.05 16 297323 1023 90330085
Lung transplant rejection 12.12 9.05 16 297323 1025 90330083
Affect lability 12.11 9.05 101 297238 17962 90313146
Faciobrachial dystonic seizure 12.10 9.05 3 297336 3 90331105
Coxsackie myocarditis 12.10 9.05 3 297336 3 90331105
Nodular regenerative hyperplasia 12.10 9.05 13 297326 670 90330438
Blood calcium increased 12.09 9.05 13 297326 12045 90319063
Meningitis chemical 12.09 9.05 9 297330 284 90330824
Encephalitis brain stem 12.08 9.05 7 297332 143 90330965
Moraxella infection 12.08 9.05 11 297328 463 90330645
Occult blood 12.07 9.05 18 297321 1293 90329815
Type 1 diabetes mellitus 12.06 9.05 39 297300 4773 90326335
Rhinovirus infection 12.05 9.05 45 297294 5918 90325190
Bile duct stenosis 12.05 9.05 21 297318 1721 90329387
Nasal septum disorder 12.03 9.05 8 297331 210 90330898
Carotid artery occlusion 12.00 9.05 3 297336 6339 90324769
Eosinopenia 12.00 9.05 6 297333 90 90331018
Dysstasia 12.00 9.05 42 297297 25010 90306098
Vaginal discharge 11.97 9.05 29 297310 19435 90311673
Lung squamous cell carcinoma metastatic 11.96 9.05 4 297335 19 90331089
White blood cell count increased 11.93 9.05 297 297042 66944 90264164
Enteritis 11.91 9.05 66 297273 10255 90320853
Lymphocele 11.91 9.05 14 297325 797 90330311
Palmar erythema 11.89 9.05 22 297317 1889 90329219
Reticulocytopenia 11.88 9.05 6 297333 92 90331016
Injection site discolouration 11.85 9.05 8 297331 9312 90321796
Morganella infection 11.84 9.05 14 297325 802 90330306
Fluorosis 11.82 9.05 7 297332 149 90330959
Meningitis pneumococcal 11.82 9.05 11 297328 476 90330632
Blood creatine phosphokinase decreased 11.80 9.05 13 297326 689 90330419
Microangiopathic haemolytic anaemia 11.80 9.05 14 297325 805 90330303
Hepatic artery aneurysm 11.79 9.05 4 297335 20 90331088
Dermatofibrosarcoma protuberans 11.79 9.05 5 297334 50 90331058
Endometrial disorder 11.77 9.05 14 297325 807 90330301
Portal vein embolism 11.77 9.05 6 297333 94 90331014
Periprosthetic fracture 11.74 9.05 12 297327 583 90330525
Diverticular perforation 11.74 9.05 33 297306 3739 90327369
Anaphylactic reaction 11.73 9.05 373 296966 87151 90243957
Hypocalcaemia 11.72 9.05 86 297253 42282 90288826
Anogenital warts 11.69 9.05 12 297327 586 90330522
Bladder cancer recurrent 11.67 9.05 8 297331 221 90330887
Tri-iodothyronine free increased 11.64 9.05 8 297331 222 90330886
Arthritis salmonella 11.63 9.05 4 297335 21 90331087
Haematemesis 11.61 9.05 64 297275 33662 90297446
Acute myocardial infarction 11.59 9.05 67 297272 34823 90296285
Hepatic failure 11.58 9.05 189 297150 39539 90291569
Meningitis fungal 11.54 9.05 6 297333 98 90331010
Vitiligo 11.54 9.05 23 297316 2087 90329021
Psoriasis 11.54 9.05 383 296956 147371 90183737
Hepatitis acute 11.50 9.05 68 297271 10819 90320289
Dehiscence 11.50 9.05 7 297332 157 90330951
Tachycardia 11.49 9.05 630 296709 157043 90174065
Hepatic artery thrombosis 11.49 9.05 6 297333 99 90331009
Ureteric obstruction 11.48 9.05 23 297316 2095 90329013
Coagulation factor VIII level increased 11.48 9.05 4 297335 22 90331086
Hospice care 11.47 9.05 9 297330 9695 90321413
Ureteral necrosis 11.45 9.05 5 297334 54 90331054
Cerebral vasoconstriction 11.44 9.05 17 297322 1217 90329891
Serum ferritin decreased 11.41 9.05 26 297313 2588 90328520
Aspergillus test positive 11.41 9.05 10 297329 400 90330708
Head injury 11.40 9.05 58 297281 31130 90299978
Inflammatory marker increased 11.36 9.05 60 297279 9154 90321954
Magnetic resonance imaging abnormal 11.35 9.05 31 297308 3455 90327653
Blood urea increased 11.35 9.05 151 297188 30262 90300846
Cystitis klebsiella 11.34 9.05 8 297331 232 90330876
Myocardial calcification 11.34 9.05 8 297331 232 90330876
Retinal degeneration 11.34 9.05 16 297323 1093 90330015
Graft ischaemia 11.33 9.05 6 297333 102 90331006
Magnesium deficiency 11.28 9.05 13 297326 724 90330384
Transaminases increased 11.24 9.05 178 297161 37014 90294094
Blood beta-D-glucan increased 11.19 9.05 9 297330 319 90330789
Inflammation 11.19 9.05 704 296635 177888 90153220
Granulicatella bacteraemia 11.19 9.05 4 297335 24 90331084
Lymphocyte count increased 11.19 9.05 34 297305 4025 90327083
Aplasia pure red cell 11.17 9.05 40 297299 5154 90325954
Cerebral toxoplasmosis 11.13 9.05 18 297321 1387 90329721
Vaccination site inflammation 11.06 9.05 5 297334 59 90331049
Culture stool positive 11.05 9.05 9 297330 325 90330783
Phlebitis 11.03 9.05 51 297288 7379 90323729
Spinal stroke 10.99 9.05 5 297334 60 90331048
Ear discomfort 10.96 9.05 64 297275 10136 90320972
Low cardiac output syndrome 10.94 9.05 10 297329 423 90330685
Specific gravity urine increased 10.93 9.05 8 297331 246 90330862
Eosinophil percentage increased 10.92 9.05 15 297324 999 90330109
Pseudomonal sepsis 10.90 9.05 35 297304 4267 90326841
Angiosarcoma 10.90 9.05 8 297331 247 90330861
Skin hyperplasia 10.89 9.05 3 297336 6 90331102
Haemangioma-thrombocytopenia syndrome 10.89 9.05 3 297336 6 90331102
Osseous cryptococcosis 10.89 9.05 3 297336 6 90331102
Abortion spontaneous 10.88 9.05 119 297220 53937 90277171
Subcutaneous haematoma 10.87 9.05 21 297318 1862 90329246
Skin oedema 10.85 9.05 16 297323 1138 90329970
White blood cell count decreased 10.84 9.05 443 296896 166666 90164442
Personality disorder 10.84 9.05 74 297265 12370 90318738
Coloboma 10.83 9.05 6 297333 112 90330996
Salmonellosis 10.82 9.05 17 297322 1278 90329830
Injection site induration 10.82 9.05 11 297328 10457 90320651
Proctitis 10.82 9.05 21 297318 15238 90315870
Ear swelling 10.76 9.05 21 297318 1876 90329232
Double stranded DNA antibody positive 10.76 9.05 10 297329 432 90330676
Eyelid sensory disorder 10.74 9.05 6 297333 114 90330994
Drug withdrawal syndrome 10.74 9.05 53 297286 28670 90302438
Joint injury 10.70 9.05 63 297276 32601 90298507
Transfusion-related acute lung injury 10.69 9.05 7 297332 179 90330929
Pneumoperitoneum 10.68 9.05 20 297319 1733 90329375
Oculomotor study abnormal 10.67 9.05 4 297335 28 90331080
Adult T-cell lymphoma/leukaemia 10.65 9.05 8 297331 256 90330852
Second primary malignancy 10.62 9.05 11 297328 10367 90320741
Blood catecholamines abnormal 10.58 9.05 3 297336 7 90331101
Small intestinal obstruction 10.58 9.05 35 297304 21199 90309909
Periodontal inflammation 10.55 9.05 4 297335 29 90331079
Beta 2 microglobulin increased 10.54 9.05 8 297331 260 90330848
Brain oedema 10.51 9.05 95 297244 17290 90313818
Leukocyturia 10.50 9.05 19 297320 1603 90329505
Lupus myocarditis 10.50 9.05 5 297334 67 90331041
Unmasking of previously unidentified disease 10.48 9.05 18 297321 1458 90329650
Monocyte percentage decreased 10.47 9.05 8 297331 263 90330845
Intestine transplant rejection 10.43 9.05 5 297334 68 90331040
Upper respiratory tract infection 10.42 9.05 518 296821 127800 90203308
Bacillus bacteraemia 10.42 9.05 6 297333 121 90330987
B-lymphocyte count increased 10.42 9.05 6 297333 121 90330987
Urinary casts 10.40 9.05 13 297326 789 90330319
Renal disorder 10.40 9.05 77 297262 37782 90293326
Eczema 10.39 9.05 117 297222 52753 90278355
Encephalopathy 10.39 9.05 212 297127 46232 90284876
Complications of transplanted heart 10.38 9.05 6 297333 122 90330986
Vasculitis necrotising 10.36 9.05 12 297327 672 90330436
Cardiac disorder 10.35 9.05 128 297211 56744 90274364
Polychondritis 10.35 9.05 12 297327 673 90330435
Hemivertebra 10.33 9.05 6 297333 123 90330985
Secondary amyloidosis 10.32 9.05 7 297332 190 90330918
Hilar lymphadenopathy 10.31 9.05 17 297322 1331 90329777
Herpes zoster meningoradiculitis 10.30 9.05 3 297336 8 90331100
Weight decreased 10.30 9.05 1090 296249 378820 89952288
Complications of transplant surgery 10.29 9.05 7 297332 191 90330917
JC polyomavirus test positive 10.29 9.05 20 297319 1782 90329326
Ankylosing spondylitis 10.28 9.05 17 297322 13116 90317992
Uterine perforation 10.27 9.05 6 297333 7548 90323560
Cerebral fungal infection 10.26 9.05 8 297331 271 90330837
Lupus endocarditis 10.26 9.05 8 297331 271 90330837
Rhinorrhoea 10.22 9.05 370 296969 87946 90243162
Paralogism 10.21 9.05 4 297335 32 90331076
Salmonella test positive 10.21 9.05 4 297335 32 90331076
Erythema migrans 10.21 9.05 4 297335 32 90331076
Tuberculosis of genitourinary system 10.21 9.05 4 297335 32 90331076
Hypoalbuminaemia 10.19 9.05 88 297251 15809 90315299
Thyroid stimulating immunoglobulin 10.18 9.05 5 297334 72 90331036
Severe myoclonic epilepsy of infancy 10.18 9.05 5 297334 72 90331036
Central nervous system lupus 10.17 9.05 17 297322 1346 90329762
Neoplasm progression 10.16 9.05 95 297244 44391 90286717
Granulomatous liver disease 10.16 9.05 14 297325 935 90330173
Nervous system disorder 10.15 9.05 112 297227 21481 90309627
Cytokine storm 10.13 9.05 11 297328 574 90330534
Epstein-Barr virus test positive 10.13 9.05 12 297327 689 90330419
Metastases to central nervous system 10.12 9.05 27 297312 17515 90313593
Anti-glomerular basement membrane disease 10.12 9.05 5 297334 73 90331035
Central nervous system function test abnormal 10.10 9.05 4 297335 33 90331075
Subacute sclerosing panencephalitis 10.10 9.05 4 297335 33 90331075
Oesophageal adenocarcinoma recurrent 10.10 9.05 4 297335 33 90331075
Lower respiratory tract congestion 10.10 9.05 29 297310 3327 90327781
Oropharyngeal candidiasis 10.10 9.05 16 297323 1212 90329896
Sopor 10.08 9.05 44 297295 24600 90306508
Device failure 10.08 9.05 5 297334 6892 90324216
Extravasation blood 10.08 9.05 6 297333 129 90330979
Administration site bruise 10.04 9.05 10 297329 471 90330637
Visual tracking test abnormal 10.04 9.05 3 297336 9 90331099
Mucous stools 10.01 9.05 39 297300 5232 90325876
Lung infiltration 10.01 9.05 85 297254 15197 90315911
Pulse pressure increased 10.00 9.05 6 297333 131 90330977
Nitrite urine 10.00 9.05 4 297335 34 90331074
Sleep apnoea syndrome 10.00 9.05 62 297277 31685 90299423
Pain in extremity 9.99 9.05 1310 296029 449219 89881889
Injection site rash 9.99 9.05 43 297296 24130 90306978
Evans syndrome 9.96 9.05 9 297330 375 90330733
Blood magnesium decreased 9.95 9.05 23 297316 15670 90315438
Herpes simplex hepatitis 9.93 9.05 11 297328 587 90330521
Atrioventricular block first degree 9.92 9.05 8 297331 8503 90322605
Fungal sepsis 9.91 9.05 18 297321 1523 90329585
Respiration abnormal 9.91 9.05 7 297332 7956 90323152
Coma 9.91 9.05 173 297166 72459 90258649
Factor XIII Inhibition 9.90 9.05 4 297335 35 90331073
Terminal ileitis 9.88 9.05 16 297323 1234 90329874
Ocular procedural complication 9.86 9.05 9 297330 380 90330728
Subcutaneous emphysema 9.86 9.05 15 297324 1097 90330011
Waxy flexibility 9.84 9.05 6 297333 135 90330973
Bone marrow reticulin fibrosis 9.83 9.05 7 297332 206 90330902
Trigeminal nerve disorder 9.83 9.05 7 297332 206 90330902
Viral upper respiratory tract infection 9.82 9.05 55 297284 8579 90322529
Hypoxia 9.82 9.05 309 297030 72090 90259018
Gastroenteritis salmonella 9.80 9.05 13 297326 837 90330271
Tachypnoea 9.77 9.05 110 297229 21199 90309909
Mycobacterium kansasii infection 9.76 9.05 6 297333 137 90330971
Vein disorder 9.74 9.05 40 297299 5496 90325612
Organising pneumonia 9.73 9.05 50 297289 7547 90323561
Tonsillitis 9.73 9.05 47 297292 6922 90324186
Autophony 9.70 9.05 4 297335 37 90331071
Ingrown hair 9.67 9.05 11 297328 604 90330504
Thrombocytosis 9.62 9.05 47 297292 6954 90324154
Dissociation 9.62 9.05 5 297334 6710 90324398
Actinomycosis 9.61 9.05 15 297324 1121 90329987
Vein collapse 9.61 9.05 15 297324 1121 90329987
Plasma cells decreased 9.61 9.05 4 297335 38 90331070
Neuralgia 9.61 9.05 151 297188 31349 90299759
Tick-borne viral encephalitis 9.61 9.05 6 297333 141 90330967
Cell-mediated immune deficiency 9.60 9.05 5 297334 82 90331026
Lower respiratory tract infection bacterial 9.60 9.05 10 297329 497 90330611
Histiocytic sarcoma 9.60 9.05 5 297334 82 90331026
Neuropathy peripheral 9.56 9.05 360 296979 136610 90194498
CSF glucose decreased 9.55 9.05 5 297334 83 90331025
Euthyroid sick syndrome 9.55 9.05 5 297334 83 90331025
Retinal depigmentation 9.54 9.05 8 297331 301 90330807
Blindness 9.54 9.05 131 297208 26437 90304671
Nodal osteoarthritis 9.51 9.05 14 297325 994 90330114
Loefgren syndrome 9.50 9.05 6 297333 144 90330964
Leishmaniasis 9.49 9.05 5 297334 84 90331024
Relapsing multiple sclerosis 9.48 9.05 7 297332 218 90330890
Mucosal inflammation 9.48 9.05 252 297087 57373 90273735
Renal cell carcinoma 9.46 9.05 31 297308 3820 90327288
Graft complication 9.43 9.05 8 297331 306 90330802
Colour blindness acquired 9.42 9.05 6 297333 146 90330962
Carcinoma in situ 9.42 9.05 6 297333 146 90330962
Hyperkalaemia 9.42 9.05 153 297186 64811 90266297
Cortisol decreased 9.41 9.05 19 297320 1740 90329368
Skin irritation 9.41 9.05 19 297320 13584 90317524
Adjusted calcium decreased 9.40 9.05 7 297332 221 90330887
Viral uveitis 9.39 9.05 6 297333 147 90330961
Complement factor C3 decreased 9.38 9.05 8 297331 308 90330800
Splenic embolism 9.38 9.05 3 297336 12 90331096
Peritonitis lupus 9.38 9.05 3 297336 12 90331096
Ecthyma 9.38 9.05 9 297330 405 90330703
Haematuria 9.38 9.05 164 297175 34773 90296335
Surgery 9.36 9.05 98 297241 44789 90286319
Leukodystrophy 9.35 9.05 4 297335 41 90331067
Upper airway necrosis 9.35 9.05 4 297335 41 90331067
Abdominal pain 9.34 9.05 1146 296193 394575 89936533
Laryngitis 9.33 9.05 114 297225 50639 90280469
Viral myocarditis 9.32 9.05 9 297330 408 90330700
Blood creatine decreased 9.32 9.05 6 297333 149 90330959
Injection site extravasation 9.31 9.05 56 297283 8963 90322145
Erosive duodenitis 9.30 9.05 10 297329 516 90330592
Tuberous sclerosis complex 9.29 9.05 5 297334 88 90331020
Wound abscess 9.28 9.05 6 297333 150 90330958
Histology abnormal 9.28 9.05 6 297333 150 90330958
Ophthalmic herpes simplex 9.28 9.05 11 297328 632 90330476
Chronic active Epstein-Barr virus infection 9.26 9.05 4 297335 42 90331066
Therapeutic product effect incomplete 9.23 9.05 531 296808 193365 90137743
Latent tuberculosis 9.23 9.05 26 297313 2950 90328158
Atypical mycobacterial infection 9.23 9.05 18 297321 1608 90329500
Complement deficiency disease 9.19 9.05 3 297336 13 90331095
Otitis externa 9.19 9.05 20 297319 1931 90329177
Colitis microscopic 9.15 9.05 14 297325 11145 90319963
Fistula 9.14 9.05 16 297323 12073 90319035
Bowel movement irregularity 9.11 9.05 5 297334 6509 90324599
Neonatal pneumonia 9.10 9.05 4 297335 44 90331064
Urine bilirubin increased 9.10 9.05 4 297335 44 90331064
Acute motor axonal neuropathy 9.10 9.05 4 297335 44 90331064
Rectal ulcer haemorrhage 9.08 9.05 7 297332 233 90330875
Immature granulocyte count increased 9.08 9.05 10 297329 530 90330578
Aspartate aminotransferase abnormal 9.07 9.05 24 297315 2625 90328483
Coccidioidomycosis 9.07 9.05 15 297324 1178 90329930
Cardio-respiratory arrest 9.06 9.05 149 297190 62991 90268117
Blood viscosity abnormal 9.06 9.05 7 297332 234 90330874

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Off label use 1591.22 10.37 5694 157869 632641 41825131
Cytomegalovirus infection 1067.98 10.37 929 162634 31377 42426395
Drug ineffective 769.23 10.37 4567 158996 625630 41832142
Drug ineffective for unapproved indication 694.80 10.37 871 162692 45292 42412480
Transplant rejection 581.13 10.37 454 163109 13134 42444638
Death 437.26 10.37 711 162852 470474 41987298
Aspergillus infection 426.20 10.37 406 163157 15431 42442341
Post transplant lymphoproliferative disorder 418.99 10.37 318 163245 8802 42448970
Pneumocystis jirovecii pneumonia 410.76 10.37 495 163068 24686 42433086
Multiple organ dysfunction syndrome 401.89 10.37 1040 162523 95995 42361777
Mucormycosis 368.35 10.37 267 163296 6876 42450896
Respiratory failure 358.50 10.37 1194 162369 126938 42330834
Product use in unapproved indication 353.81 10.37 1523 162040 182933 42274839
Bronchopulmonary aspergillosis 353.57 10.37 404 163159 19025 42438747
Kidney transplant rejection 345.26 10.37 278 163285 8405 42449367
Strongyloidiasis 330.44 10.37 190 163373 3241 42454531
Posterior reversible encephalopathy syndrome 328.59 10.37 320 163243 12501 42445271
Septic shock 327.88 10.37 931 162632 90741 42367031
Polyomavirus-associated nephropathy 326.83 10.37 226 163337 5389 42452383
Epstein-Barr virus infection 321.94 10.37 280 163283 9438 42448334
Cytomegalovirus infection reactivation 290.23 10.37 281 163282 10897 42446875
Completed suicide 283.66 10.37 23 163540 96442 42361330
Fatigue 283.03 10.37 802 162761 434839 42022933
Cytomegalovirus viraemia 282.94 10.37 268 163295 10109 42447663
Graft versus host disease 278.98 10.37 294 163269 12631 42445141
Enterococcal infection 274.48 10.37 282 163281 11757 42446015
Drug abuse 263.34 10.37 43 163520 104728 42353044
Fall 249.09 10.37 321 163242 234199 42223573
Thrombotic microangiopathy 231.94 10.37 285 163278 14497 42443275
Nocardiosis 227.48 10.37 176 163387 5014 42452758
Dizziness 224.91 10.37 382 163181 248872 42208900
Nausea 220.63 10.37 783 162780 396016 42061756
Adenovirus infection 213.16 10.37 190 163373 6619 42451153
Haemophagocytic lymphohistiocytosis 208.44 10.37 301 163262 17921 42439851
Pseudomonas infection 205.94 10.37 279 163284 15644 42442128
BK virus infection 202.50 10.37 207 163356 8577 42449195
Acute graft versus host disease in skin 193.42 10.37 187 163376 7237 42450535
Graft versus host disease in gastrointestinal tract 186.30 10.37 156 163407 4987 42452785
Candida infection 180.53 10.37 309 163254 21301 42436471
Pulmonary nocardiosis 178.92 10.37 102 163461 1710 42456062
Rebound effect 177.60 10.37 178 163385 7201 42450571
Product dose omission issue 176.78 10.37 199 163364 154166 42303606
Drug effective for unapproved indication 176.43 10.37 169 163394 6464 42451308
Klebsiella infection 175.39 10.37 217 163346 11115 42446657
Pneumatosis intestinalis 171.85 10.37 144 163419 4608 42453164
Cytomegalovirus colitis 163.67 10.37 130 163433 3851 42453921
Complications of transplanted kidney 160.98 10.37 146 163417 5204 42452568
Parvovirus B19 infection 158.95 10.37 93 163470 1641 42456131
Constipation 157.28 10.37 237 163326 162054 42295718
Toxicity to various agents 153.38 10.37 415 163148 228721 42229051
Pneumonia cytomegaloviral 153.29 10.37 127 163436 3999 42453773
Pneumomediastinum 150.54 10.37 112 163451 3004 42454768
Cystitis haemorrhagic 146.34 10.37 160 163403 7169 42450603
Cardiac failure congestive 142.92 10.37 75 163488 85527 42372245
Therapy non-responder 140.81 10.37 488 163075 52871 42404901
Infusion related reaction 139.22 10.37 531 163032 60275 42397497
Disseminated mucormycosis 133.86 10.37 77 163486 1314 42456458
Acute graft versus host disease in liver 133.61 10.37 87 163476 1871 42455901
Steroid diabetes 132.20 10.37 100 163463 2752 42455020
Blood pressure fluctuation 131.98 10.37 308 163255 26600 42431172
Disease recurrence 131.92 10.37 327 163236 29351 42428421
Vomiting 129.30 10.37 622 162941 289101 42168671
Myocardial infarction 129.13 10.37 172 163391 123837 42333935
Hospitalisation 128.77 10.37 62 163501 74268 42383504
Immunosuppressant drug level increased 124.42 10.37 151 163412 7580 42450192
Acute graft versus host disease in intestine 123.17 10.37 110 163453 3841 42453931
Acute respiratory distress syndrome 122.67 10.37 321 163242 29787 42427985
Asthenia 120.58 10.37 611 162952 280182 42177590
Intentional overdose 118.84 10.37 26 163537 51430 42406342
Infection reactivation 117.66 10.37 84 163479 2110 42455662
Escherichia infection 117.05 10.37 179 163384 11217 42446555
Cerebrovascular accident 117.01 10.37 120 163443 97040 42360732
Overdose 116.88 10.37 139 163424 105125 42352647
Dehydration 116.33 10.37 230 163333 141537 42316235
Human herpesvirus 6 infection 115.86 10.37 88 163475 2437 42455335
Syncope 113.90 10.37 128 163435 99278 42358494
Cushingoid 112.12 10.37 98 163465 3324 42454448
Graft versus host disease in skin 111.47 10.37 118 163445 5094 42452678
Depression 104.60 10.37 166 163397 111197 42346575
Hypogammaglobulinaemia 104.57 10.37 174 163389 11717 42446055
Herpes simplex 102.06 10.37 131 163432 6964 42450808
Delayed graft function 101.85 10.37 83 163480 2552 42455220
Acute graft versus host disease 101.77 10.37 141 163422 8074 42449698
Chronic allograft nephropathy 101.75 10.37 68 163495 1530 42456242
Focal segmental glomerulosclerosis 97.94 10.37 80 163483 2468 42455304
Drug resistance 97.18 10.37 321 163242 33927 42423845
Injection site pain 95.93 10.37 51 163512 57747 42400025
COVID-19 95.37 10.37 766 162797 115182 42342590
Chronic graft versus host disease 94.24 10.37 116 163447 5909 42451863
Nephropathy toxic 92.91 10.37 202 163361 16636 42441136
Fungal infection 92.64 10.37 222 163341 19500 42438272
Confusional state 92.59 10.37 331 163232 167266 42290506
Myopathy 92.36 10.37 179 163384 13582 42444190
Disseminated intravascular coagulation 91.61 10.37 255 163308 24539 42433233
Stress 91.28 10.37 28 163535 44184 42413588
Polyomavirus viraemia 91.20 10.37 71 163492 2041 42455731
Decreased appetite 91.16 10.37 406 163157 192731 42265041
Cytomegalovirus test positive 90.98 10.37 97 163466 4222 42453550
Condition aggravated 89.84 10.37 1452 162111 259302 42198470
Progressive multifocal leukoencephalopathy 88.61 10.37 159 163404 11377 42446395
Dyspnoea 88.47 10.37 1183 162380 441438 42016334
Cryptococcosis 87.65 10.37 83 163480 3128 42454644
COVID-19 pneumonia 87.59 10.37 230 163333 21383 42436389
Bacterial sepsis 87.51 10.37 116 163447 6366 42451406
Somnolence 86.65 10.37 266 163297 140839 42316933
Penicillium infection 83.06 10.37 35 163528 289 42457483
Corynebacterium infection 82.63 10.37 48 163515 835 42456937
Full blood count abnormal 80.29 10.37 10 163553 29866 42427906
Diarrhoea 79.77 10.37 1267 162296 459582 41998190
Pulmonary mucormycosis 78.70 10.37 56 163507 1399 42456373
Pain 77.32 10.37 586 162977 244262 42213510
Blood pressure diastolic abnormal 77.15 10.37 106 163457 6022 42451750
Enterobacter infection 76.99 10.37 75 163488 2929 42454843
Pneumonia cryptococcal 76.90 10.37 56 163507 1452 42456320
Liver transplant rejection 76.43 10.37 69 163494 2444 42455328
Renal tubular atrophy 76.40 10.37 55 163508 1400 42456372
Feeling abnormal 74.44 10.37 95 163468 69691 42388081
Pneumocystis jirovecii infection 74.42 10.37 72 163491 2788 42454984
Transplant dysfunction 73.83 10.37 77 163486 3266 42454506
Stenotrophomonas infection 72.45 10.37 80 163483 3624 42454148
Suicide attempt 71.74 10.37 44 163519 46056 42411716
Cardiac disorder 71.68 10.37 50 163513 48882 42408890
Systemic candida 71.52 10.37 95 163468 5224 42452548
Lymphopenia 71.19 10.37 213 163350 21350 42436422
Leukopenia 71.07 10.37 511 163052 74235 42383537
Hypoglycaemia 70.82 10.37 75 163488 59779 42397993
Cytomegalovirus enteritis 70.12 10.37 39 163524 622 42457150
Nightmare 68.13 10.37 8 163555 25004 42432768
Anxiety 67.56 10.37 231 163332 118329 42339443
Dry skin 67.42 10.37 52 163511 48286 42409486
Malaise 66.37 10.37 509 163054 211647 42246125
Coronary artery disease 66.19 10.37 65 163498 53655 42404117
JC virus infection 66.00 10.37 69 163494 2935 42454837
Acinetobacter infection 65.10 10.37 51 163512 1480 42456292
Kidney fibrosis 64.29 10.37 65 163498 2657 42455115
Transplant failure 63.47 10.37 78 163485 3966 42453806
Wrong technique in product usage process 63.20 10.37 43 163520 42592 42415180
Muscle spasms 62.73 10.37 149 163414 85895 42371877
Pneumonia klebsiella 62.27 10.37 79 163484 4150 42453622
Subcutaneous emphysema 62.23 10.37 52 163511 1657 42456115
Suicidal ideation 62.01 10.37 56 163507 48105 42409667
Back pain 61.57 10.37 307 163256 141469 42316303
Renal transplant failure 61.55 10.37 49 163514 1456 42456316
Herpes simplex pneumonia 60.94 10.37 27 163536 255 42457517
Rhinocerebral mucormycosis 60.60 10.37 36 163527 654 42457118
Epstein-Barr viraemia 60.27 10.37 58 163505 2231 42455541
Transient ischaemic attack 60.18 10.37 27 163536 33712 42424060
Central nervous system viral infection 59.86 10.37 23 163540 145 42457627
Skin striae 59.79 10.37 37 163526 726 42457046
Osteonecrosis 59.43 10.37 164 163399 15701 42442071
Rhabdomyolysis 58.57 10.37 133 163430 77886 42379886
Cytomegalovirus oesophagitis 57.95 10.37 33 163530 552 42457220
Large intestine perforation 57.94 10.37 119 163444 9417 42448355
Varicella zoster virus infection 57.61 10.37 60 163503 2541 42455231
Disseminated cryptococcosis 56.87 10.37 52 163511 1873 42455899
Aplastic anaemia 56.66 10.37 138 163425 12246 42445526
Blood pressure systolic increased 56.55 10.37 235 163328 27733 42430039
Disseminated varicella zoster virus infection 56.49 10.37 36 163527 745 42457027
Intentional product misuse 56.47 10.37 94 163469 61806 42395966
Systemic mycosis 56.37 10.37 57 163506 2330 42455442
Hyperglycaemia 56.07 10.37 334 163229 45525 42412247
Pneumonia fungal 55.41 10.37 114 163449 9032 42448740
Prostate cancer 55.02 10.37 54 163509 44589 42413183
Balance disorder 54.93 10.37 61 163502 47584 42410188
Oxygen saturation decreased 54.58 10.37 430 163133 64257 42393515
Fusarium infection 54.40 10.37 47 163516 1569 42456203
Central nervous system fungal infection 54.36 10.37 29 163534 424 42457348
Necrotising retinitis 54.23 10.37 39 163524 991 42456781
Blood pressure systolic abnormal 54.21 10.37 85 163478 5443 42452329
Growth retardation 53.68 10.37 56 163507 2376 42455396
Immunosuppressant drug level decreased 53.36 10.37 49 163514 1775 42455997
Malacoplakia 53.32 10.37 37 163526 887 42456885
Accidental overdose 53.21 10.37 21 163542 28309 42429463
Oliguria 52.84 10.37 113 163450 9200 42448572
Bacteraemia 51.88 10.37 212 163351 24828 42432944
Fungaemia 51.68 10.37 62 163501 3074 42454698
Pneumonia pseudomonal 51.67 10.37 78 163485 4831 42452941
Insomnia 51.37 10.37 256 163307 117997 42339775
Oedema peripheral 50.68 10.37 310 163253 135766 42322006
Blood immunoglobulin G decreased 50.57 10.37 53 163510 2261 42455511
Plasma cell myeloma 50.49 10.37 65 163498 47513 42410259
Pneumoretroperitoneum 50.41 10.37 20 163543 139 42457633
Enterocolitis viral 50.21 10.37 28 163535 449 42457323
Loss of personal independence in daily activities 49.89 10.37 71 163492 49745 42408027
Phaeohyphomycosis 49.39 10.37 39 163524 1145 42456627
Malignant neoplasm progression 49.21 10.37 231 163332 108169 42349603
Pneumonia bacterial 48.98 10.37 152 163411 15540 42442232
Tremor 48.59 10.37 199 163364 96730 42361042
Staphylococcal infection 48.50 10.37 278 163285 37365 42420407
Ear pruritus 48.47 10.37 32 163531 705 42457067
Aplasia 48.23 10.37 75 163488 4768 42453004
Cytomegalovirus chorioretinitis 48.16 10.37 73 163490 4538 42453234
Headache 47.92 10.37 639 162924 238730 42219042
Graft versus host disease in liver 47.89 10.37 44 163519 1595 42456177
Ureaplasma infection 47.71 10.37 30 163533 606 42457166
Mycobacterium abscessus infection 47.57 10.37 32 163531 728 42457044
Pruritus 47.46 10.37 479 163084 188292 42269480
Lymphocyte count decreased 47.37 10.37 222 163341 27587 42430185
Diffuse alveolar damage 47.31 10.37 54 163509 2538 42455234
Pathogen resistance 46.54 10.37 122 163441 11328 42446444
Abdominal discomfort 46.06 10.37 142 163421 75113 42382659
Glomerulonephritis 46.06 10.37 53 163510 2513 42455259
Amoebic colitis 45.95 10.37 17 163546 95 42457677
Extrapyramidal disorder 45.33 10.37 5 163558 16407 42441365
Hyperhidrosis 45.26 10.37 186 163377 90326 42367446
Pneumonia acinetobacter 45.17 10.37 21 163542 224 42457548
Cerebral fungal infection 44.98 10.37 24 163539 351 42457421
Chest pain 44.89 10.37 332 163231 139198 42318574
Cutaneous mucormycosis 44.85 10.37 29 163534 616 42457156
Epstein-Barr virus associated lymphoproliferative disorder 44.76 10.37 51 163512 2392 42455380
Atrial fibrillation 44.51 10.37 333 163230 139260 42318512
Thrombosis 44.29 10.37 126 163437 68385 42389387
Renal tubular necrosis 44.23 10.37 163 163400 18191 42439581
Gastroenteritis norovirus 44.13 10.37 43 163520 1680 42456092
International normalised ratio increased 44.06 10.37 73 163490 48095 42409677
Pemphigus 43.94 10.37 46 163517 1960 42455812
Scedosporium infection 43.92 10.37 41 163522 1517 42456255
Immunosuppression 43.91 10.37 99 163464 8354 42449418
Fungal skin infection 43.89 10.37 59 163504 3282 42454490
Staphylococcal sepsis 43.75 10.37 119 163444 11295 42446477
Osteomyelitis fungal 43.49 10.37 23 163540 330 42457442
Osteoporosis 43.43 10.37 141 163422 14765 42443007
Human herpesvirus 8 infection 43.37 10.37 40 163523 1457 42456315
Medication error 43.34 10.37 38 163525 33116 42424656
Mycobacterium chelonae infection 43.22 10.37 36 163527 1142 42456630
Abdominal abscess 42.75 10.37 73 163490 5020 42452752
Disseminated strongyloidiasis 42.42 10.37 26 163537 501 42457271
Hallucination 42.37 10.37 99 163464 57408 42400364
Opportunistic infection 42.25 10.37 45 163518 1956 42455816
Pain in extremity 42.18 10.37 372 163191 150232 42307540
Lethargy 42.03 10.37 72 163491 46818 42410954
Product prescribing error 41.92 10.37 24 163539 26088 42431684
Cryptococcal meningoencephalitis 41.85 10.37 19 163544 191 42457581
Diffuse large B-cell lymphoma 41.82 10.37 104 163459 9350 42448422
Peripheral swelling 41.78 10.37 191 163372 90079 42367693
Pneumothorax 41.62 10.37 190 163373 23353 42434419
Viraemia 41.31 10.37 42 163521 1728 42456044
Dyskinesia 41.25 10.37 23 163540 25367 42432405
Disseminated blastomycosis 40.90 10.37 23 163540 375 42457397
Myalgia 40.58 10.37 210 163353 95870 42361902
Pseudomonal bacteraemia 40.52 10.37 48 163515 2348 42455424
Lung abscess 40.41 10.37 56 163507 3207 42454565
Cytomegalovirus enterocolitis 40.16 10.37 37 163526 1346 42456426
Adverse drug reaction 39.87 10.37 51 163512 37383 42420389
Depressed mood 39.73 10.37 20 163543 23364 42434408
Granulomatosis with polyangiitis 39.65 10.37 38 163525 1454 42456318
Cytomegalovirus hepatitis 39.63 10.37 25 163538 508 42457264
Apoptosis 39.61 10.37 26 163537 567 42457205
Product quality issue 39.37 10.37 10 163553 17872 42439900
Glomerulosclerosis 39.09 10.37 30 163533 844 42456928
Herpes simplex hepatitis 38.98 10.37 17 163546 154 42457618
Blood pressure increased 38.95 10.37 578 162985 101350 42356422
Symptom masked 38.88 10.37 30 163533 851 42456921
Dry mouth 38.79 10.37 58 163505 39821 42417951
Intensive care unit acquired weakness 38.69 10.37 35 163528 1243 42456529
Sepsis 38.65 10.37 1020 162543 198314 42259458
Aggression 38.51 10.37 69 163494 44094 42413678
Accidental exposure to product 38.49 10.37 15 163548 20378 42437394
Heart rate decreased 38.39 10.37 256 163307 36276 42421496
Enterococcal bacteraemia 37.98 10.37 49 163514 2618 42455154
Injection site erythema 37.88 10.37 15 163548 20180 42437592
Swollen tongue 37.85 10.37 17 163546 21214 42436558
Sleep disorder 37.72 10.37 80 163483 48015 42409757
Sedation 37.39 10.37 37 163526 30438 42427334
Miosis 37.38 10.37 4 163559 13442 42444330
Osmotic demyelination syndrome 37.28 10.37 31 163532 981 42456791
Unevaluable event 37.26 10.37 46 163517 34242 42423530
Neuroleptic malignant syndrome 37.03 10.37 18 163545 21454 42436318
Heart transplant rejection 36.90 10.37 37 163526 1497 42456275
Incorrect dose administered 36.82 10.37 94 163469 52880 42404892
Abdominal pain 36.81 10.37 512 163051 189959 42267813
White blood cell count decreased 36.80 10.37 260 163303 110136 42347636
Contraindicated product administered 36.77 10.37 26 163537 25246 42432526
Gait disturbance 36.61 10.37 223 163340 97777 42359995
Asthma 36.43 10.37 120 163443 62194 42395578
Pharyngeal paraesthesia 35.91 10.37 29 163534 880 42456892
Renal tubular injury 35.79 10.37 39 163524 1740 42456032
Erectile dysfunction 35.77 10.37 26 163537 24887 42432885
Splenic embolism 35.48 10.37 19 163544 280 42457492
Incision site pain 35.33 10.37 40 163523 1863 42455909
Restlessness 35.33 10.37 36 163527 29213 42428559
Proteinuria 35.21 10.37 178 163385 22805 42434967
Liver abscess 35.01 10.37 66 163497 4904 42452868
Therapy partial responder 34.96 10.37 161 163402 19860 42437912
Bradycardia 34.89 10.37 189 163374 85295 42372477
Cardiac infection 34.55 10.37 18 163545 250 42457522
Haemolytic uraemic syndrome 34.45 10.37 45 163518 2434 42455338
Central nervous system infection 34.22 10.37 28 163535 866 42456906
Respiratory tract infection fungal 34.21 10.37 27 163536 792 42456980
Treatment failure 34.04 10.37 379 163184 62245 42395527
Dysgeusia 33.96 10.37 49 163514 34140 42423632
Idiopathic pneumonia syndrome 33.95 10.37 22 163541 469 42457303
Herpes zoster 33.65 10.37 260 163303 38617 42419155
Dural arteriovenous fistula 33.37 10.37 12 163551 61 42457711
Renal graft infection 33.35 10.37 20 163543 370 42457402
Chorioretinopathy 33.34 10.37 35 163528 1496 42456276
Blastomycosis 33.33 10.37 25 163538 679 42457093
Hyponatraemia 33.30 10.37 240 163323 101222 42356550
Arteriosclerosis coronary artery 33.22 10.37 15 163548 18662 42439110
Polychondritis 33.11 10.37 20 163543 375 42457397
Pneumoperitoneum 32.78 10.37 43 163520 2335 42455437
Cytomegalovirus gastrointestinal infection 32.43 10.37 19 163544 336 42457436
Histoplasmosis disseminated 32.28 10.37 40 163523 2051 42455721
Adverse event 32.24 10.37 26 163537 23614 42434158
Respiratory arrest 32.09 10.37 37 163526 28387 42429385
Epstein-Barr virus associated lymphoma 31.89 10.37 29 163534 1037 42456735
Red blood cells urine positive 31.87 10.37 38 163525 1872 42455900
Sideroblastic anaemia 31.85 10.37 19 163544 348 42457424
New onset diabetes after transplantation 31.71 10.37 16 163547 207 42457565
Shock haemorrhagic 31.68 10.37 135 163428 16107 42441665
Parvovirus infection 31.48 10.37 21 163542 471 42457301
Full blood count decreased 31.46 10.37 20 163543 20540 42437232
Hypoalbuminaemia 31.42 10.37 131 163432 15479 42442293
Chronic obstructive pulmonary disease 31.35 10.37 130 163433 62984 42394788
Obliterative bronchiolitis 31.10 10.37 33 163530 1428 42456344
Ventricular fibrillation 31.09 10.37 42 163521 30081 42427691
Neuropathy peripheral 31.03 10.37 246 163317 101607 42356165
Psoriasis 30.96 10.37 90 163473 48514 42409258
Epstein-Barr virus infection reactivation 30.92 10.37 44 163519 2583 42455189
Rheumatoid arthritis 30.92 10.37 273 163290 42167 42415605
Human ehrlichiosis 30.87 10.37 21 163542 487 42457285
Quadriplegia 30.86 10.37 40 163523 2147 42455625
Aplasia pure red cell 30.82 10.37 78 163485 7088 42450684
Gastroduodenal ulcer 30.79 10.37 24 163539 691 42457081
Enterococcus test positive 30.58 10.37 35 163528 1650 42456122
Herpes zoster meningoencephalitis 30.53 10.37 21 163542 496 42457276
Contusion 30.35 10.37 73 163490 41912 42415860
Unresponsive to stimuli 30.23 10.37 46 163517 31357 42426415
Rash 30.06 10.37 821 162742 276133 42181639
Encephalitis cytomegalovirus 30.02 10.37 30 163533 1209 42456563
Product substitution issue 29.80 10.37 4 163559 11286 42446486
American trypanosomiasis 29.78 10.37 18 163545 338 42457434
Monkeypox 29.74 10.37 19 163544 395 42457377
Electrocardiogram QT prolonged 29.66 10.37 90 163473 47855 42409917
Hypocomplementaemia 29.65 10.37 11 163552 62 42457710
Escherichia sepsis 29.51 10.37 67 163496 5680 42452092
Viral haemorrhagic cystitis 29.49 10.37 36 163527 1818 42455954
Steroid withdrawal syndrome 29.45 10.37 17 163546 292 42457480
Orthostatic hypotension 29.21 10.37 45 163518 30525 42427247
Swelling 29.20 10.37 110 163453 54775 42402997
Hepatitis E 29.09 10.37 47 163516 3087 42454685
Eczema 29.05 10.37 54 163509 34032 42423740
Viral sepsis 29.05 10.37 13 163550 126 42457646
Wheezing 29.01 10.37 110 163453 54671 42403101
Appendicitis 28.96 10.37 22 163541 20591 42437181
Empyema 28.82 10.37 55 163508 4125 42453647
Blood immunoglobulin M decreased 28.77 10.37 25 163538 841 42456931
Human polyomavirus infection 28.75 10.37 30 163533 1273 42456499
Trichosporon infection 28.68 10.37 26 163537 926 42456846
Salivary hypersecretion 28.59 10.37 4 163559 10939 42446833
Abdominal distension 28.51 10.37 160 163403 71575 42386197
Skin necrosis 28.50 10.37 70 163493 6244 42451528
Dysphagia 28.46 10.37 163 163400 72556 42385216
Orchitis 28.43 10.37 39 163524 2212 42455560
Dyspnoea exertional 28.34 10.37 98 163465 50050 42407722
Blood creatine phosphokinase increased 28.31 10.37 93 163470 48245 42409527
Injection site swelling 28.12 10.37 15 163548 16958 42440814
Staphylococcal mediastinitis 28.11 10.37 10 163553 49 42457723
Thyrotoxic periodic paralysis 28.10 10.37 14 163549 176 42457596
Low birth weight baby 27.95 10.37 93 163470 9862 42447910
Fluid retention 27.92 10.37 49 163514 31570 42426202
Autoimmune haemolytic anaemia 27.89 10.37 65 163498 5606 42452166
Ecthyma 27.86 10.37 22 163541 646 42457126
Tularaemia 27.82 10.37 14 163549 180 42457592
Gastritis fungal 27.77 10.37 13 163550 141 42457631
Cytokine release syndrome 27.72 10.37 277 163286 44250 42413522
Smooth muscle cell neoplasm 27.56 10.37 16 163547 278 42457494
Atypical mycobacterial pneumonia 27.54 10.37 15 163548 229 42457543
Spinal cord injury cervical 27.46 10.37 16 163547 280 42457492
Klebsiella sepsis 27.14 10.37 42 163521 2659 42455113
Obstructive airways disorder 27.13 10.37 33 163530 24726 42433046
Laboratory test abnormal 26.94 10.37 29 163534 22949 42434823
Respiratory symptom 26.91 10.37 5 163558 11101 42446671
Palpitations 26.90 10.37 102 163461 50695 42407077
Cholelithiasis 26.78 10.37 30 163533 23316 42434456
Osteoporotic fracture 26.77 10.37 31 163532 1480 42456292
Splenic infection viral 26.75 10.37 9 163554 36 42457736
T-cell type acute leukaemia 26.65 10.37 14 163549 198 42457574
Encephalopathy 26.64 10.37 259 163304 41074 42416698
Perinephric abscess 26.58 10.37 10 163553 59 42457713
Drug intolerance 26.50 10.37 190 163373 80234 42377538
Cardiac failure 26.47 10.37 272 163291 106584 42351188
Activated partial thromboplastin time prolonged 26.42 10.37 14 163549 15889 42441883
Hepatic failure 26.18 10.37 242 163321 37858 42419914
Lymphangitis 26.18 10.37 21 163542 631 42457141
Lymphocele 26.18 10.37 31 163532 1516 42456256
Ureteric stenosis 26.12 10.37 28 163535 1226 42456546
Encephalitis brain stem 25.98 10.37 13 163550 165 42457607
Herpes virus infection 25.97 10.37 49 163514 3643 42454129
Hepatic artery thrombosis 25.92 10.37 15 163548 259 42457513
Disseminated toxoplasmosis 25.87 10.37 15 163548 260 42457512
Peritonitis 25.58 10.37 140 163423 18493 42439279
Bronchopneumopathy 25.57 10.37 20 163543 579 42457193
Brain abscess 25.48 10.37 53 163510 4231 42453541
Lupus nephritis 25.46 10.37 19 163544 512 42457260
Hypophagia 25.45 10.37 40 163523 26916 42430856
Tuberculosis 25.44 10.37 91 163472 10008 42447764
Pericarditis fungal 25.30 10.37 14 163549 221 42457551
Bronchopleural fistula 25.22 10.37 21 163542 666 42457106
Superinfection bacterial 25.20 10.37 29 163534 1375 42456397
Substance-induced psychotic disorder 25.03 10.37 42 163521 2847 42454925
Injection site haemorrhage 25.01 10.37 7 163556 11729 42446043
Anaemia 24.96 10.37 853 162710 279425 42178347
Pneumocephalus 24.74 10.37 13 163550 184 42457588
Arrhythmia 24.71 10.37 76 163487 40241 42417531
Reticulocytosis 24.66 10.37 15 163548 285 42457487
Acute hepatic failure 24.61 10.37 130 163433 16943 42440829
Dyspepsia 24.61 10.37 79 163484 41273 42416499
Psoriatic arthropathy 24.58 10.37 36 163527 24931 42432841
Loss of consciousness 24.58 10.37 231 163332 92123 42365649
Pyrexia 24.33 10.37 1790 161773 392252 42065520
Neck pain 24.32 10.37 49 163514 29965 42427807
Pulmonary alveolar haemorrhage 24.30 10.37 117 163446 14699 42443073
Serratia sepsis 24.29 10.37 12 163551 148 42457624
Limbic encephalitis 24.23 10.37 17 163546 415 42457357
Graft complication 24.21 10.37 21 163542 705 42457067
Disease progression 24.15 10.37 722 162841 142934 42314838
Scopulariopsis infection 24.15 10.37 12 163551 150 42457622
Alveolar proteinosis 24.11 10.37 21 163542 709 42457063
Hepatic artery aneurysm 24.08 10.37 9 163554 52 42457720
Incorrect route of product administration 23.98 10.37 35 163528 24270 42433502
Meningitis fungal 23.90 10.37 13 163550 198 42457574
Respiratory tract inflammation 23.78 10.37 17 163546 428 42457344
Spinal cord abscess 23.74 10.37 17 163546 429 42457343
Graft loss 23.74 10.37 23 163540 892 42456880
Leukocytosis 23.69 10.37 195 163368 29513 42428259
Agitation 23.67 10.37 147 163416 64167 42393605
Herpes simplex viraemia 23.61 10.37 11 163552 118 42457654
Lymphocytosis 23.56 10.37 42 163521 2989 42454783
Organising pneumonia 23.54 10.37 73 163490 7459 42450313
Gastrointestinal candidiasis 23.53 10.37 12 163551 159 42457613
Blood sodium decreased 23.51 10.37 21 163542 18141 42439631
Inflammatory marker increased 23.50 10.37 68 163495 6688 42451084
Graft infection 23.47 10.37 17 163546 437 42457335
Seizure 23.30 10.37 324 163239 120237 42337535
Blood beta-D-glucan increased 23.28 10.37 18 163545 512 42457260
Product storage error 23.09 10.37 7 163556 11133 42446639
Renal impairment 23.07 10.37 570 162993 109658 42348114
Human herpesvirus 6 infection reactivation 23.04 10.37 17 163546 450 42457322
Palmar-plantar erythrodysaesthesia syndrome 23.01 10.37 27 163536 20555 42437217
Frequent bowel movements 22.96 10.37 29 163534 21378 42436394
Multiple-drug resistance 22.92 10.37 71 163492 7251 42450521
Adenoviral haemorrhagic cystitis 22.90 10.37 18 163545 525 42457247
Bordetella infection 22.89 10.37 12 163551 169 42457603
Granuloma 22.89 10.37 49 163514 3992 42453780
Coronary artery dilatation 22.86 10.37 8 163555 37 42457735
Mobility decreased 22.76 10.37 65 163498 35241 42422531
Protein urine present 22.75 10.37 61 163502 5740 42452032
B-cell lymphoma 22.74 10.37 55 163508 4858 42452914
Infective aneurysm 22.69 10.37 24 163539 1035 42456737
Nephritis 22.68 10.37 47 163516 3742 42454030
Exposure during pregnancy 22.63 10.37 3 163560 8545 42449227
Treatment noncompliance 22.40 10.37 72 163491 37600 42420172
Hypertension 22.37 10.37 818 162745 166386 42291386
Disturbance in attention 22.33 10.37 51 163512 29815 42427957
Epididymitis 22.26 10.37 41 163522 2993 42454779
Blood pressure decreased 22.16 10.37 132 163431 58200 42399572
Throat irritation 22.15 10.37 104 163459 12932 42444840
Chromophobe renal cell carcinoma 22.04 10.37 9 163554 68 42457704
Glycosylated haemoglobin increased 22.04 10.37 11 163552 12913 42444859
Enterovirus infection 22.03 10.37 26 163537 1267 42456505
Small intestinal perforation 21.90 10.37 40 163523 2901 42454871
Device related sepsis 21.86 10.37 47 163516 3840 42453932
Glomerulonephritis rapidly progressive 21.78 10.37 22 163541 898 42456874
Anti-neutrophil cytoplasmic antibody positive vasculitis 21.64 10.37 28 163535 1500 42456272
Angiosarcoma 21.60 10.37 15 163548 360 42457412
Haemolytic anaemia 21.53 10.37 98 163465 12029 42445743
Post procedural bile leak 21.42 10.37 14 163549 303 42457469
Renal cyst infection 21.40 10.37 10 163553 108 42457664
Multi-organ disorder 21.34 10.37 26 163537 1310 42456462
Arthralgia 21.32 10.37 612 162951 204626 42253146
Flatulence 21.30 10.37 40 163523 25112 42432660
Drug withdrawal syndrome 21.29 10.37 31 163532 21518 42436254
Urinary tract infection bacterial 21.26 10.37 35 163528 2335 42455437
Cerebral aspergillosis 21.26 10.37 30 163533 1747 42456025
Secondary immunodeficiency 21.24 10.37 21 163542 835 42456937
Pseudomonal sepsis 21.22 10.37 49 163514 4200 42453572
Cystitis escherichia 21.22 10.37 12 163551 198 42457574
Abdominal wall abscess 21.19 10.37 19 163544 667 42457105
Hyperkalaemia 21.09 10.37 202 163361 80256 42377516
Memory impairment 21.06 10.37 110 163453 50112 42407660
Neuromyelitis optica spectrum disorder 21.01 10.37 13 163550 255 42457517
Needle issue 20.99 10.37 4 163559 8723 42449049
Mycobacterium marinum infection 20.99 10.37 17 163546 518 42457254
Autoimmune thyroiditis 20.88 10.37 28 163535 1554 42456218
Device issue 20.86 10.37 13 163550 13496 42444276
Blindness 20.73 10.37 129 163434 17849 42439923
Familial periodic paralysis 20.67 10.37 11 163552 160 42457612
Intestinal ischaemia 20.66 10.37 81 163482 9307 42448465
Myoclonus 20.61 10.37 21 163542 17044 42440728
Rectal haemorrhage 20.61 10.37 109 163454 49497 42408275
Plasmodium falciparum infection 20.59 10.37 9 163554 82 42457690
Injection site reaction 20.57 10.37 18 163545 15703 42442069
Atrial septal defect 20.45 10.37 3 163560 7916 42449856
Respiratory distress 20.44 10.37 248 163315 41572 42416200
Neurological decompensation 20.38 10.37 45 163518 3744 42454028
Gastrooesophageal reflux disease 20.38 10.37 96 163467 44927 42412845
Encephalitis fungal 20.35 10.37 12 163551 215 42457557
Adenoviral hepatitis 20.34 10.37 17 163546 542 42457230
Immune reconstitution inflammatory syndrome 20.32 10.37 85 163478 10058 42447714
Platelet count decreased 20.30 10.37 392 163171 138189 42319583
Oesophageal carcinoma 20.26 10.37 6 163557 9690 42448082
Irritability 20.26 10.37 49 163514 28079 42429693
Poisoning 20.25 10.37 16 163547 14683 42443089
Torulopsis infection 20.23 10.37 6 163557 14 42457758
Hypoaesthesia 20.21 10.37 176 163387 71287 42386485
Listeriosis 20.21 10.37 26 163537 1385 42456387
Mycoplasma infection 20.19 10.37 18 163545 627 42457145
Red blood cell schistocytes present 20.16 10.37 14 163549 336 42457436
Serum sickness 20.15 10.37 33 163530 2192 42455580
Endocarditis 20.15 10.37 73 163490 8079 42449693
Encephalitis 20.14 10.37 79 163484 9079 42448693
Monocytopenia 20.13 10.37 9 163554 87 42457685
Nephrolithiasis 20.12 10.37 73 163490 36757 42421015
Diaphragmatic injury 20.05 10.37 10 163553 126 42457646
Hypersomnia 20.03 10.37 16 163547 14602 42443170
Cryptitis 20.03 10.37 13 163550 278 42457494
Blindness cortical 20.02 10.37 16 163547 478 42457294
Coma 19.92 10.37 122 163441 53432 42404340
Marginal zone lymphoma 19.91 10.37 10 163553 128 42457644
Hepatic cirrhosis 19.80 10.37 28 163535 19674 42438098
Skin exfoliation 19.77 10.37 87 163476 41466 42416306
Candida sepsis 19.72 10.37 26 163537 1419 42456353
Bifidobacterium infection 19.69 10.37 9 163554 92 42457680
Pyelonephritis 19.67 10.37 71 163492 7843 42449929
Therapy cessation 19.64 10.37 30 163533 20420 42437352
Vision blurred 19.62 10.37 123 163440 53576 42404196
Cytomegalovirus nephritis 19.58 10.37 10 163553 133 42457639
Infectious pleural effusion 19.56 10.37 40 163523 3155 42454617
Cavernous sinus thrombosis 19.53 10.37 11 163552 180 42457592
Cutaneous malacoplakia 19.51 10.37 10 163553 134 42457638
Cytomegalovirus gastritis 19.51 10.37 13 163550 291 42457481
Mycobacterial infection 19.51 10.37 36 163527 2632 42455140
Tracheobronchitis 19.49 10.37 25 163538 1328 42456444
Muscle rigidity 19.48 10.37 11 163552 12048 42445724
Gastrointestinal perforation 19.47 10.37 49 163514 4437 42453335
Abnormal dreams 19.46 10.37 4 163559 8267 42449505
Type I hypersensitivity 19.45 10.37 32 163531 2134 42455638
Bladder cancer 19.45 10.37 22 163541 17025 42440747
Necrosis 19.45 10.37 63 163500 6588 42451184
Panic attack 19.44 10.37 9 163554 11036 42446736
Toxic epidermal necrolysis 19.44 10.37 172 163391 26578 42431194
Hyperphosphataemia 19.42 10.37 13 163550 12991 42444781
Blood phosphorus increased 19.42 10.37 12 163551 12513 42445259
Pulmonary haemorrhage 19.42 10.37 91 163472 11306 42446466
Complications of transplant surgery 19.41 10.37 16 163547 500 42457272
Status epilepticus 19.38 10.37 114 163449 15464 42442308
Intentional product use issue 19.31 10.37 385 163178 71448 42386324
Epstein-Barr virus test positive 19.28 10.37 18 163545 666 42457106
Drug hypersensitivity 19.23 10.37 267 163296 99122 42358650
Akathisia 19.21 10.37 8 163555 10443 42447329
Prescribed overdose 19.20 10.37 13 163550 12914 42444858
Therapy interrupted 19.18 10.37 35 163528 22215 42435557
B-lymphocyte count decreased 19.16 10.37 20 163543 849 42456923
Inappropriate schedule of product administration 19.14 10.37 256 163307 95646 42362126
Haemodynamic instability 19.06 10.37 97 163466 12460 42445312
Neutrophil percentage increased 18.97 10.37 30 163533 1935 42455837
Disseminated aspergillosis 18.94 10.37 28 163535 1702 42456070
Meningitis cryptococcal 18.81 10.37 40 163523 3243 42454529
Angina pectoris 18.78 10.37 64 163499 32832 42424940
Necrosis ischaemic 18.77 10.37 14 163549 377 42457395
Gastrointestinal mucormycosis 18.77 10.37 14 163549 377 42457395
Respiratory disorder 18.72 10.37 147 163416 21938 42435834
Cutaneous B-cell lymphoma 18.68 10.37 8 163555 69 42457703
Blood pressure diastolic decreased 18.53 10.37 84 163479 10291 42447481
Episcleritis 18.51 10.37 11 163552 200 42457572
Kidney rupture 18.46 10.37 11 163552 201 42457571
Gastrointestinal ulcer 18.45 10.37 29 163534 1861 42455911
Drug interaction 18.45 10.37 837 162726 266162 42191610
Intestine transplant rejection 18.37 10.37 7 163556 43 42457729
Trichophytosis 18.36 10.37 14 163549 390 42457382
Intra-abdominal haemorrhage 18.33 10.37 37 163526 2891 42454881
Pancreas transplant rejection 18.32 10.37 11 163552 204 42457568
Colorectal adenocarcinoma 18.30 10.37 13 163550 324 42457448
Hospice care 18.29 10.37 5 163558 8508 42449264
Nocturia 18.24 10.37 12 163551 12100 42445672
Breath sounds abnormal 18.18 10.37 12 163551 12081 42445691
Fibrin D dimer increased 18.14 10.37 51 163512 4934 42452838
Intestinal intraepithelial lymphocytes increased 18.13 10.37 11 163552 208 42457564
Gonococcal infection 18.10 10.37 7 163556 45 42457727
Intentional self-injury 18.03 10.37 19 163544 15183 42442589
Fungal abscess central nervous system 18.01 10.37 10 163553 159 42457613
Hemianopia 18.00 10.37 20 163543 912 42456860
Blood potassium increased 17.98 10.37 27 163536 18509 42439263
Oesophageal candidiasis 17.97 10.37 55 163508 5580 42452192
Retching 17.95 10.37 4 163559 7817 42449955
Pulmonary embolism 17.93 10.37 337 163226 119275 42338497
Clostridium colitis 17.90 10.37 26 163537 1555 42456217
Amnesia 17.86 10.37 53 163510 28384 42429388
Pulmonary tuberculosis 17.83 10.37 54 163509 5447 42452325
Urine analysis abnormal 17.83 10.37 31 163532 2163 42455609
Respiratory depression 17.81 10.37 28 163535 18840 42438932
General physical health deterioration 17.79 10.37 443 163120 150803 42306969
Fungal peritonitis 17.78 10.37 20 163543 925 42456847
Visceral leishmaniasis 17.70 10.37 22 163541 1132 42456640
Gastroenteritis Escherichia coli 17.67 10.37 20 163543 931 42456841
Cardio-respiratory arrest 17.67 10.37 142 163421 58494 42399278
Micturition urgency 17.63 10.37 12 163551 11886 42445886
Donor specific antibody present 17.63 10.37 10 163553 166 42457606
Neutrophil count decreased 17.57 10.37 157 163406 63258 42394514
Demodicidosis 17.55 10.37 11 163552 221 42457551
Enteritis 17.44 10.37 85 163478 10731 42447041
Klebsiella bacteraemia 17.41 10.37 32 163531 2332 42455440
Mycotic endophthalmitis 17.37 10.37 11 163552 225 42457547
Venoocclusive liver disease 17.36 10.37 82 163481 10220 42447552
Forced expiratory volume decreased 17.32 10.37 4 163559 7626 42450146
Faeces discoloured 17.28 10.37 24 163539 16990 42440782
Tracheobronchitis viral 17.28 10.37 6 163557 27 42457745
Arterial spasm 17.24 10.37 8 163555 85 42457687
Escherichia urinary tract infection 17.24 10.37 46 163517 4317 42453455
Dermatophytosis 17.17 10.37 12 163551 291 42457481
Cryptosporidiosis infection 17.15 10.37 18 163545 769 42457003
Leishmaniasis 17.14 10.37 14 163549 432 42457340
Alcohol poisoning 17.14 10.37 4 163559 7570 42450202
Duodenal perforation 17.11 10.37 26 163537 1620 42456152
Herpes simplex reactivation 17.08 10.37 15 163548 512 42457260
Tardive dyskinesia 17.03 10.37 3 163560 6921 42450851
Epistaxis 17.00 10.37 169 163394 66657 42391115
Lichenoid keratosis 16.99 10.37 43 163520 3907 42453865
Staphylococcal bacteraemia 16.94 10.37 86 163477 11035 42446737
Critical illness 16.91 10.37 11 163552 236 42457536
Disseminated tuberculosis 16.87 10.37 35 163528 2789 42454983
Sputum purulent 16.81 10.37 17 163546 695 42457077
Amoebiasis 16.76 10.37 8 163555 91 42457681
Passenger lymphocyte syndrome 16.68 10.37 8 163555 92 42457680
Blood cholesterol increased 16.68 10.37 50 163513 26691 42431081
Nephrotic syndrome 16.64 10.37 72 163491 8646 42449126
Hypothyroidism 16.61 10.37 65 163498 32019 42425753
Injection site bruising 16.58 10.37 12 163551 11513 42446259
Herpes simplex colitis 16.48 10.37 5 163558 13 42457759
Post procedural urine leak 16.38 10.37 9 163554 140 42457632
Pollakiuria 16.37 10.37 39 163524 22466 42435306
Microscopic polyangiitis 16.36 10.37 11 163552 250 42457522
Head injury 16.33 10.37 34 163529 20548 42437224
Febrile neutropenia 16.31 10.37 566 162997 185137 42272635
Viral cardiomyopathy 16.30 10.37 6 163557 33 42457739
Orbital infection 16.29 10.37 7 163556 61 42457711
Acute respiratory failure 16.28 10.37 224 163339 38634 42419138
Gastroenteritis rotavirus 16.25 10.37 12 163551 318 42457454
Tracheitis 16.24 10.37 20 163543 1019 42456753
Hepatic necrosis 16.22 10.37 42 163521 3871 42453901
Cerebral venous thrombosis 16.21 10.37 20 163543 1021 42456751
Mediastinitis 16.15 10.37 20 163543 1025 42456747
Bacillus infection 16.15 10.37 17 163546 729 42457043
Subdural haematoma 16.12 10.37 41 163522 23097 42434675
Urine abnormality 16.10 10.37 30 163533 2209 42455563
Urethral polyp 16.09 10.37 7 163556 63 42457709
Lymphocytic infiltration 16.08 10.37 19 163544 927 42456845
Subcapsular renal haematoma 16.07 10.37 15 163548 555 42457217
Eye infection fungal 16.06 10.37 14 163549 473 42457299
Serratia infection 16.05 10.37 22 163541 1247 42456525
Dementia 15.99 10.37 24 163539 16456 42441316
Abdominal infection 15.97 10.37 32 163531 2487 42455285
Urinary tract infection enterococcal 15.97 10.37 20 163543 1037 42456735
Tumefactive multiple sclerosis 15.90 10.37 7 163556 65 42457707
Immune thrombocytopenia 15.89 10.37 85 163478 11131 42446641
Bursitis infective 15.86 10.37 16 163547 652 42457120
Acute disseminated encephalomyelitis 15.83 10.37 9 163554 150 42457622
Marrow hyperplasia 15.81 10.37 22 163541 1265 42456507
Necrotising soft tissue infection 15.73 10.37 9 163554 152 42457620
Astrovirus test positive 15.73 10.37 6 163557 37 42457735
Blood uric acid increased 15.72 10.37 22 163541 15525 42442247
Pneumonia escherichia 15.66 10.37 16 163547 662 42457110
Serum ferritin increased 15.65 10.37 62 163501 7157 42450615
Uraemic encephalopathy 15.64 10.37 13 163550 411 42457361
Impaired work ability 15.63 10.37 14 163549 12077 42445695
Madarosis 15.60 10.37 14 163549 492 42457280
Abdominal pain upper 15.60 10.37 223 163340 82386 42375386
Troponin increased 15.54 10.37 31 163532 19031 42438741
Sarcopenia 15.53 10.37 18 163545 860 42456912
Ageusia 15.53 10.37 13 163550 11592 42446180
SJS-TEN overlap 15.53 10.37 16 163547 669 42457103
Blood pressure diastolic increased 15.53 10.37 57 163506 6348 42451424
Lymph gland infection 15.48 10.37 10 163553 212 42457560
Delirium 15.45 10.37 128 163435 52391 42405381
Arteritis infective 15.45 10.37 7 163556 70 42457702
Fungal sepsis 15.42 10.37 20 163543 1074 42456698
Candida pneumonia 15.41 10.37 17 163546 769 42457003
Sudden death 15.39 10.37 25 163538 16604 42441168
Paraplegia 15.36 10.37 37 163526 3260 42454512
Urobilinogen urine increased 15.35 10.37 12 163551 347 42457425
Skin discolouration 15.35 10.37 36 163527 20854 42436918
Meningioma malignant 15.33 10.37 6 163557 40 42457732
Osteopenia 15.33 10.37 56 163507 6222 42451550
Haemoperitoneum 15.26 10.37 28 163535 2038 42455734
Blood immunoglobulin A decreased 15.26 10.37 16 163547 683 42457089
Herpes oesophagitis 15.22 10.37 9 163554 162 42457610
Short stature 15.22 10.37 13 163550 427 42457345
Venoocclusive disease 15.19 10.37 41 163522 3874 42453898
Gastric disorder 15.18 10.37 14 163549 11908 42445864
Acinetobacter sepsis 15.18 10.37 8 163555 114 42457658
Torsade de pointes 15.13 10.37 7 163556 8587 42449185
Peritoneal candidiasis 15.06 10.37 5 163558 19 42457753
Mental impairment 15.05 10.37 15 163548 12302 42445470
Paranoia 15.05 10.37 19 163544 14007 42443765
Fear 15.03 10.37 12 163551 10953 42446819
Pulmonary air leakage 14.96 10.37 10 163553 225 42457547
Serotonin syndrome 14.94 10.37 50 163513 25795 42431977
Vaccination failure 14.94 10.37 23 163540 1449 42456323
West Nile viral infection 14.90 10.37 18 163545 899 42456873
Listeria sepsis 14.85 10.37 10 163553 228 42457544
Atypical mycobacterial infection 14.80 10.37 22 163541 1344 42456428
Hepatic cancer 14.79 10.37 7 163556 8473 42449299
Feeding intolerance 14.75 10.37 11 163552 296 42457476
Anuria 14.74 10.37 85 163478 11447 42446325
MAGIC syndrome 14.73 10.37 6 163557 45 42457727
Crystal urine present 14.72 10.37 13 163550 447 42457325
Central nervous system vasculitis 14.72 10.37 15 163548 619 42457153
Microangiopathic haemolytic anaemia 14.68 10.37 20 163543 1127 42456645
Oral lichenoid reaction 14.64 10.37 8 163555 123 42457649
Fungal endocarditis 14.63 10.37 13 163550 451 42457321
Vasculitis gastrointestinal 14.62 10.37 6 163557 46 42457726
Microsporidia infection 14.61 10.37 20 163543 1132 42456640
Peripheral artery aneurysm 14.58 10.37 14 163549 537 42457235
Underdose 14.56 10.37 26 163537 16640 42441132
Lung transplant rejection 14.54 10.37 19 163544 1028 42456744
Sexual dysfunction 14.51 10.37 4 163559 6771 42451001
Ureteric anastomosis complication 14.51 10.37 6 163557 47 42457725
Ventricular extrasystoles 14.51 10.37 18 163545 13372 42444400
Blood glucose decreased 14.50 10.37 20 163543 14199 42443573
Mesenteric haemorrhage 14.49 10.37 5 163558 22 42457750
Pleural mass 14.48 10.37 7 163556 82 42457690
Faciobrachial dystonic seizure 14.48 10.37 7 163556 82 42457690
Ileal ulcer 14.48 10.37 18 163545 926 42456846
Central nervous system abscess 14.40 10.37 6 163557 48 42457724
Cryoglobulinaemia 14.39 10.37 14 163549 546 42457226
Bacterial translocation 14.35 10.37 15 163548 638 42457134
Investigation abnormal 14.33 10.37 15 163548 639 42457133
Acute hepatitis C 14.31 10.37 8 163555 129 42457643
Splenic abscess 14.25 10.37 15 163548 643 42457129
Ejection fraction abnormal 14.24 10.37 21 163542 1274 42456498
Lymphoproliferative disorder 14.23 10.37 36 163527 3271 42454501
Hepatitis A 14.22 10.37 14 163549 554 42457218
Hypocalvaria 14.19 10.37 6 163557 50 42457722
Palatal ulcer 14.19 10.37 6 163557 50 42457722
Erosive duodenitis 14.18 10.37 25 163538 1764 42456008
Keratitis 14.16 10.37 25 163538 1766 42456006
Accelerated idioventricular rhythm 14.13 10.37 9 163554 186 42457586
Acinetobacter bacteraemia 14.13 10.37 9 163554 186 42457586
Migraine 14.13 10.37 50 163513 25364 42432408
Tinnitus 14.12 10.37 60 163503 28878 42428894
Intestinal ulcer 14.12 10.37 19 163544 1058 42456714
Chimerism 14.12 10.37 10 163553 248 42457524
Retinal detachment 14.12 10.37 56 163507 6469 42451303
Lung neoplasm malignant 14.07 10.37 33 163530 19114 42438658
Electrocardiogram abnormal 14.03 10.37 11 163552 10134 42447638
Gait inability 14.02 10.37 43 163520 22790 42434982
Activated partial thromboplastin time shortened 13.97 10.37 13 163550 479 42457293
Clonal haematopoiesis 13.97 10.37 9 163554 190 42457582
Hypophosphataemia 13.92 10.37 38 163525 20907 42436865
Herpes simplex oesophagitis 13.91 10.37 10 163553 254 42457518
Pancreatitis 13.87 10.37 103 163460 43165 42414607
Hypocalcaemia 13.85 10.37 64 163499 30109 42427663
Restless legs syndrome 13.84 10.37 10 163553 9604 42448168
Eye pruritus 13.83 10.37 14 163549 11398 42446374
Aspiration 13.81 10.37 30 163533 17856 42439916
Pneumonia necrotising 13.78 10.37 19 163544 1083 42456689
Seronegative arthritis 13.67 10.37 20 163543 1204 42456568
Unmasking of previously unidentified disease 13.61 10.37 20 163543 1209 42456563
Eye luxation 13.59 10.37 4 163559 9 42457763
Kaposi's sarcoma 13.57 10.37 16 163547 779 42456993
Thrombocytopenia 13.55 10.37 875 162688 189404 42268368
ADAMTS13 activity decreased 13.53 10.37 8 163555 144 42457628
Central nervous system lesion 13.53 10.37 63 163500 7807 42449965
Lip ulceration 13.52 10.37 18 163545 992 42456780
Disseminated trichosporonosis 13.51 10.37 7 163556 96 42457676
Musculoskeletal stiffness 13.50 10.37 149 163414 57616 42400156
Lymphocyte percentage decreased 13.50 10.37 28 163535 2231 42455541
Cystitis viral 13.45 10.37 20 163543 1222 42456550
Granulomatous liver disease 13.43 10.37 15 163548 688 42457084
Phaeochromocytoma 13.41 10.37 10 163553 269 42457503
Prostatic specific antigen increased 13.40 10.37 28 163535 16897 42440875
Chronic papillomatous dermatitis 13.33 10.37 6 163557 59 42457713
Priapism 13.33 10.37 4 163559 6403 42451369
Endocarditis bacterial 13.32 10.37 20 163543 1233 42456539
Blood test abnormal 13.31 10.37 18 163545 12888 42444884
Urinary retention 13.29 10.37 101 163462 42113 42415659
Hepatitis B 13.26 10.37 56 163507 6655 42451117
Femoral nerve palsy 13.24 10.37 6 163557 60 42457712
Stupor 13.23 10.37 34 163529 3119 42454653
Optic perineuritis 13.22 10.37 5 163558 30 42457742
Cutaneous nocardiosis 13.22 10.37 9 163554 209 42457563
Morganella infection 13.21 10.37 14 163549 605 42457167
Angioedema 13.20 10.37 102 163461 42375 42415397
Herpes zoster cutaneous disseminated 13.18 10.37 9 163554 210 42457562
Substance abuse 13.17 10.37 9 163554 8896 42448876
Bacterial tracheitis 13.16 10.37 6 163557 61 42457711
Interferon gamma release assay positive 13.15 10.37 8 163555 152 42457620
Therapeutic product effect decreased 13.13 10.37 92 163471 39058 42418714
Amoebic dysentery 13.07 10.37 6 163557 62 42457710
Optic nerve compression 13.02 10.37 4 163559 11 42457761
Bicytopenia 13.02 10.37 34 163529 3150 42454622
Hypopnoea 13.01 10.37 7 163556 7875 42449897
Arthritis fungal 12.96 10.37 7 163556 105 42457667
Withdrawal syndrome 12.95 10.37 23 163540 14752 42443020
Acne fulminans 12.95 10.37 10 163553 284 42457488
Mycobacterium kansasii infection 12.94 10.37 11 163552 359 42457413
Granulomatous lymphadenitis 12.92 10.37 9 163554 217 42457555
Biopsy lymph gland 12.91 10.37 6 163557 64 42457708
Delusion 12.86 10.37 23 163540 14711 42443061
Cardiogenic shock 12.83 10.37 82 163481 35558 42422214
Oral candidiasis 12.83 10.37 97 163466 14308 42443464
Infection masked 12.83 10.37 6 163557 65 42457707
Peliosis hepatis 12.83 10.37 6 163557 65 42457707
Neuromyotonia 12.82 10.37 5 163558 33 42457739
Conjunctival oedema 12.81 10.37 14 163549 627 42457145
Ovarian cancer metastatic 12.77 10.37 4 163559 12 42457760
Skin fissures 12.75 10.37 11 163552 9665 42448107
Dizziness postural 12.75 10.37 7 163556 7788 42449984
Shock symptom 12.75 10.37 8 163555 161 42457611
Joint injury 12.73 10.37 23 163540 14653 42443119
Clostridium difficile infection 12.70 10.37 138 163425 22521 42435251
Chemotherapeutic drug level above therapeutic 12.69 10.37 5 163558 34 42457738
Lipohypertrophy 12.68 10.37 10 163553 293 42457479
Pyelonephritis acute 12.67 10.37 29 163534 2471 42455301
Eschar 12.66 10.37 15 163548 734 42457038
Arterial rupture 12.65 10.37 13 163550 542 42457230
Gastric perforation 12.61 10.37 33 163530 3060 42454712
Brain herniation 12.61 10.37 44 163519 4779 42452993
Chronic hepatitis 12.58 10.37 15 163548 739 42457033
Extrapulmonary tuberculosis 12.58 10.37 8 163555 165 42457607
Infective aortitis 12.57 10.37 5 163558 35 42457737
IgA nephropathy 12.55 10.37 28 163535 2346 42455426
Inadequate aseptic technique in use of product 12.53 10.37 4 163559 13 42457759
Arteritis coronary 12.51 10.37 6 163557 69 42457703
Glomerulonephropathy 12.47 10.37 9 163554 230 42457542
Cardiovascular disorder 12.46 10.37 20 163543 13345 42444427
Acute endocarditis 12.45 10.37 5 163558 36 42457736
Drug eruption 12.43 10.37 46 163517 23029 42434743
Pleocytosis 12.38 10.37 14 163549 651 42457121
Norovirus infection 12.37 10.37 15 163548 752 42457020
Bone marrow failure 12.37 10.37 187 163376 32906 42424866
Disseminated varicella zoster vaccine virus infection 12.36 10.37 6 163557 71 42457701
Microvillous inclusion disease 12.34 10.37 9 163554 234 42457538
Complications of transplanted liver 12.31 10.37 10 163553 306 42457466
Lumbosacral plexus lesion 12.30 10.37 4 163559 14 42457758
Meconium peritonitis 12.30 10.37 4 163559 14 42457758
Coronary artery aneurysm 12.30 10.37 7 163556 117 42457655
Perforation bile duct 12.29 10.37 6 163557 72 42457700
Cytomegalovirus duodenitis 12.29 10.37 6 163557 72 42457700
Haemorrhagic pneumonia 12.29 10.37 8 163555 172 42457600
Varicella virus test positive 12.27 10.37 9 163554 236 42457536
Pharyngeal oedema 12.24 10.37 4 163559 6064 42451708
Thyroid gland abscess 12.22 10.37 6 163557 73 42457699
Eye abscess 12.17 10.37 8 163555 175 42457597
Adenomatous polyposis coli 12.13 10.37 8 163555 176 42457596
Urine bilirubin decreased 12.11 10.37 5 163558 39 42457733
Conjunctival hyperaemia 12.06 10.37 33 163530 3143 42454629
Renal haemorrhage 12.03 10.37 22 163541 1597 42456175
Chronic graft versus host disease in liver 12.03 10.37 14 163549 672 42457100
Injection site pruritus 12.02 10.37 11 163552 9394 42448378
Cardiac murmur 12.02 10.37 19 163544 12756 42445016
Gastroenteritis sapovirus 12.01 10.37 8 163555 179 42457593
Oral bacterial infection 12.00 10.37 5 163558 40 42457732
Urinary fistula 11.99 10.37 7 163556 123 42457649
Depressed level of consciousness 11.91 10.37 122 163441 47848 42409924
Fibrosarcoma 11.90 10.37 5 163558 41 42457731
Enterobacter bacteraemia 11.90 10.37 13 163550 582 42457190
Renal artery perforation 11.89 10.37 4 163559 16 42457756
Carotid artery insufficiency 11.89 10.37 4 163559 16 42457756
Wolff-Parkinson-White syndrome 11.86 10.37 9 163554 249 42457523
Haemorrhagic necrotic pancreatitis 11.85 10.37 8 163555 183 42457589
Iron deficiency 11.85 10.37 15 163548 11046 42446726
Bundle branch block left 11.84 10.37 5 163558 6471 42451301
Autoimmune colitis 11.82 10.37 18 163545 1123 42456649
Parkinsonism 11.81 10.37 14 163549 10609 42447163
Mastication disorder 11.79 10.37 23 163540 1753 42456019
Jejunal perforation 11.77 10.37 10 163553 326 42457446
Ketoacidosis 11.77 10.37 3 163560 5349 42452423
Bacterial pyelonephritis 11.75 10.37 10 163553 327 42457445
Arteriovenous fistula 11.69 10.37 18 163545 1134 42456638
Road traffic accident 11.69 10.37 36 163527 19057 42438715
Injury 11.69 10.37 45 163518 22271 42435501
Rhinovirus infection 11.68 10.37 53 163510 6495 42451277
Alternaria infection 11.66 10.37 13 163550 595 42457177
Product administration error 11.65 10.37 34 163529 18309 42439463
Encephalomyelitis 11.65 10.37 7 163556 130 42457642
Galactosaemia 11.63 10.37 3 163560 3 42457769
Papillary muscle rupture 11.63 10.37 3 163560 3 42457769
Community acquired infection 11.63 10.37 3 163560 3 42457769
Increased ventricular preload 11.63 10.37 3 163560 3 42457769
Congenital cardiovascular anomaly 11.63 10.37 8 163555 189 42457583
Hepatic infection fungal 11.61 10.37 9 163554 257 42457515
Arterial injury 11.56 10.37 11 163552 417 42457355
Knee arthroplasty 11.55 10.37 10 163553 8771 42449001
Haematuria traumatic 11.54 10.37 10 163553 335 42457437
Coinfection 11.54 10.37 6 163557 83 42457689
Hypotension 11.53 10.37 842 162721 256789 42200983
Nodular regenerative hyperplasia 11.53 10.37 17 163546 1031 42456741
Coombs direct test positive 11.52 10.37 10 163553 336 42457436
Osteomyelitis blastomyces 11.52 10.37 4 163559 18 42457754
Drug dependence 11.49 10.37 65 163498 29029 42428743
Acanthamoeba infection 11.47 10.37 12 163551 511 42457261
Electrocardiogram QRS complex prolonged 11.47 10.37 4 163559 5819 42451953
Eye irritation 11.46 10.37 16 163547 11302 42446470
Acute pulmonary histoplasmosis 11.45 10.37 8 163555 194 42457578
Liver function test 11.41 10.37 6 163557 85 42457687
Oesophageal infection 11.39 10.37 10 163553 341 42457431
Musculoskeletal pain 11.35 10.37 78 163485 33262 42424510
Mental status changes 11.35 10.37 105 163458 42010 42415762
Inhibin B 11.34 10.37 4 163559 19 42457753
Labelled drug-drug interaction medication error 11.33 10.37 27 163536 15555 42442217
Cardiac arrest 11.33 10.37 326 163237 108994 42348778
Semen volume decreased 11.32 10.37 10 163553 344 42457428
Metastases to liver 11.32 10.37 29 163534 16297 42441475
Growth disorder 11.29 10.37 6 163557 87 42457685
Weight decreased 11.27 10.37 668 162895 207280 42250492
Haptoglobin decreased 11.24 10.37 14 163549 722 42457050
Rash papulosquamous 11.23 10.37 6 163557 88 42457684
Premature baby 11.18 10.37 137 163426 23016 42434756
Body temperature decreased 11.17 10.37 94 163469 14319 42443453
Aortic valve disease mixed 11.11 10.37 6 163557 90 42457682
Subperiosteal abscess 11.11 10.37 6 163557 90 42457682
Thrombotic thrombocytopenic purpura 11.09 10.37 36 163527 3768 42454004
Campylobacter gastroenteritis 11.08 10.37 17 163546 1068 42456704
Limb discomfort 11.08 10.37 20 163543 12747 42445025
Vitello-intestinal duct remnant 11.06 10.37 7 163556 143 42457629
Exophthalmos 11.04 10.37 15 163548 843 42456929
Deafness 11.03 10.37 21 163542 13119 42444653
Megacolon 11.03 10.37 26 163537 2259 42455513
Colitis 11.01 10.37 245 163318 46327 42411445
Immune-mediated encephalitis 11.01 10.37 13 163550 634 42457138
Mood altered 11.00 10.37 15 163548 10703 42447069
Mixed liver injury 11.00 10.37 40 163523 4434 42453338
Cerebral haemorrhage 11.00 10.37 96 163467 38870 42418902
Corneal lesion 10.99 10.37 6 163557 92 42457680
Haematochezia 10.94 10.37 158 163405 58278 42399494
Testicular cancer metastatic 10.94 10.37 6 163557 93 42457679
Perineal infection 10.92 10.37 13 163550 639 42457133
Lip swelling 10.92 10.37 37 163526 19016 42438756
Acinetobacter test positive 10.89 10.37 7 163556 147 42457625
Spermatozoa progressive motility decreased 10.87 10.37 8 163555 211 42457561
SARS-CoV-2 viraemia 10.83 10.37 6 163557 95 42457677
Pancytopenia 10.80 10.37 554 163009 117189 42340583
Radiotherapy to brain 10.78 10.37 5 163558 53 42457719
Gingival pain 10.78 10.37 10 163553 8484 42449288
Mouth ulceration 10.76 10.37 96 163467 14867 42442905
Hepatic infection 10.73 10.37 14 163549 756 42457016
Pulmonary arterial hypertension 10.72 10.37 14 163549 10173 42447599
Respiratory rate increased 10.72 10.37 76 163487 10986 42446786
Osteomyelitis bacterial 10.71 10.37 10 163553 370 42457402
Hypergammaglobulinaemia 10.71 10.37 10 163553 370 42457402
Aortic pseudoaneurysm 10.70 10.37 5 163558 54 42457718
Retinal scar 10.69 10.37 10 163553 371 42457401
Enterococcal sepsis 10.68 10.37 24 163539 2020 42455752
Muscle twitching 10.63 10.37 18 163545 11762 42446010
Chromaturia 10.63 10.37 29 163534 15960 42441812
Gynaecomastia 10.63 10.37 20 163543 12547 42445225
Herpes simplex encephalitis 10.62 10.37 10 163553 374 42457398
Conus medullaris syndrome 10.62 10.37 5 163558 55 42457717
Ophthalmoplegia 10.58 10.37 25 163538 2175 42455597
Abscess sterile 10.58 10.37 4 163559 24 42457748
Periventricular haemorrhage neonatal 10.58 10.37 4 163559 24 42457748
Viral myositis 10.58 10.37 4 163559 24 42457748
Ocular hyperaemia 10.58 10.37 29 163534 15934 42441838
Cervical spinal cord paralysis 10.58 10.37 4 163559 24 42457748
Oral herpes 10.57 10.37 57 163506 7487 42450285
Citrobacter infection 10.56 10.37 13 163550 662 42457110
Vitamin B1 decreased 10.56 10.37 10 163553 377 42457395
Infective tenosynovitis 10.55 10.37 6 163557 100 42457672
Duodenal ulcer 10.55 10.37 82 163481 12197 42445575
Lower motor neurone lesion 10.54 10.37 5 163558 56 42457716
C-reactive protein increased 10.54 10.37 319 163244 63241 42394531
Probiotic therapy 10.53 10.37 7 163556 156 42457616
Haemoglobin abnormal 10.51 10.37 3 163560 4961 42452811
Colon cancer 10.50 10.37 13 163550 9668 42448104
Circumoral oedema 10.50 10.37 6 163557 101 42457671
Abnormal behaviour 10.50 10.37 59 163504 26392 42431380
Engraftment syndrome 10.47 10.37 19 163544 1371 42456401
Phaeohyphomycotic brain abscess 10.46 10.37 5 163558 57 42457715
Erythema infectiosum 10.45 10.37 7 163556 158 42457614
Herpes simplex meningoencephalitis 10.44 10.37 4 163559 25 42457747
Chorioretinal folds 10.43 10.37 3 163560 6 42457766
Herpes simplex sepsis 10.43 10.37 3 163560 6 42457766
Pneumonia adenoviral 10.43 10.37 10 163553 383 42457389
Hepatitis cholestatic 10.41 10.37 69 163494 9755 42448017
Accident 10.41 10.37 6 163557 6497 42451275

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Off label use 2677.37 9.55 12137 415122 1488048 108673992
Cytomegalovirus infection 1984.16 9.55 1661 425598 52783 110109257
Drug ineffective 1284.54 9.55 10128 417131 1510412 108651628
Drug ineffective for unapproved indication 1205.66 9.55 1724 425535 101114 110060926
Transplant rejection 877.18 9.55 741 426518 23826 110138214
Aspergillus infection 786.47 9.55 709 426550 24907 110137133
Completed suicide 774.42 9.55 39 427220 242342 109919698
Bronchopulmonary aspergillosis 766.02 9.55 748 426511 29115 110132925
Multiple organ dysfunction syndrome 638.98 9.55 1644 425615 150066 110011974
Pneumocystis jirovecii pneumonia 616.97 9.55 793 426466 41942 110120098
Product use in unapproved indication 616.46 9.55 3377 423882 444000 109718040
Posterior reversible encephalopathy syndrome 593.56 9.55 693 426566 33168 110128872
Blood pressure fluctuation 586.36 9.55 1044 426215 73780 110088260
Polyomavirus-associated nephropathy 585.96 9.55 376 426883 7825 110154215
Respiratory failure 573.83 9.55 1984 425275 213348 109948692
Cytomegalovirus viraemia 569.75 9.55 504 426755 17260 110144780
Cytomegalovirus infection reactivation 567.87 9.55 510 426749 17823 110144217
Mucormycosis 563.19 9.55 405 426854 10223 110151817
Throat irritation 544.36 9.55 840 426419 52712 110109328
Post transplant lymphoproliferative disorder 530.96 9.55 458 426801 15155 110146885
Epstein-Barr virus infection 519.62 9.55 490 426769 18248 110143792
Haemophagocytic lymphohistiocytosis 494.33 9.55 610 426649 30949 110131091
Kidney transplant rejection 483.19 9.55 388 426871 11599 110150441
BK virus infection 479.58 9.55 401 426858 12705 110149335
Enterococcal infection 477.77 9.55 486 426773 19880 110142160
Thrombotic microangiopathy 467.20 9.55 570 426689 28579 110133461
Septic shock 461.71 9.55 1499 425760 156029 110006011
Death 436.94 9.55 1321 425938 697548 109464492
Klebsiella infection 423.67 9.55 452 426807 19557 110142483
Strongyloidiasis 394.83 9.55 244 427015 4742 110157298
Nocardiosis 382.38 9.55 279 426980 7207 110154833
Drug abuse 374.56 9.55 110 427149 177301 109984739
Pseudomonas infection 366.65 9.55 494 426765 27359 110134681
Toxicity to various agents 362.87 9.55 826 426433 479729 109682311
Drug effective for unapproved indication 337.66 9.55 341 426918 13826 110148214
Adenovirus infection 321.22 9.55 296 426963 10698 110151342
Blood pressure systolic abnormal 315.37 9.55 433 426826 24417 110137623
Blood pressure diastolic abnormal 307.02 9.55 436 426823 25379 110136661
Infusion related reaction 303.40 9.55 2512 424747 378650 109783390
Graft versus host disease in gastrointestinal tract 300.74 9.55 261 426998 8707 110153333
Candida infection 298.33 9.55 607 426652 47402 110114638
COVID-19 291.31 9.55 1780 425479 243280 109918760
Intentional overdose 291.17 9.55 76 427183 132425 110029615
Graft versus host disease 290.49 9.55 361 426898 18445 110143595
Sleep disorder due to general medical condition, insomnia type 289.81 9.55 34 427225 105609 110056431
Rheumatoid factor positive 284.56 9.55 78 427181 131562 110030478
Complications of transplanted kidney 281.22 9.55 232 427027 7210 110154830
Disease recurrence 280.18 9.55 682 426577 60102 110101938
Ear pruritus 279.95 9.55 229 427030 7031 110155009
Cytomegalovirus colitis 277.06 9.55 225 427034 6836 110155204
Pneumatosis intestinalis 275.52 9.55 243 427016 8286 110153754
Pulmonary nocardiosis 269.45 9.55 152 427107 2477 110159563
Pneumomediastinum 267.04 9.55 192 427067 4844 110157196
Blood pressure increased 264.35 9.55 1807 425452 256566 109905474
Oxygen saturation decreased 261.71 9.55 1251 426008 155731 110006309
Escherichia infection 256.74 9.55 384 426875 23432 110138608
Vomiting 255.89 9.55 2269 424990 908406 109253634
Rebound effect 252.77 9.55 299 426960 14507 110147533
Fatigue 252.11 9.55 3252 424007 1212706 108949334
Blood pressure systolic increased 251.44 9.55 799 426460 82192 110079848
Progressive multifocal leukoencephalopathy 248.74 9.55 388 426871 24568 110137472
Steroid diabetes 241.94 9.55 184 427075 5070 110156970
Injection site pain 240.76 9.55 200 427059 177722 109984318
Pneumonia cytomegaloviral 234.43 9.55 203 427056 6751 110155289
Immunosuppressant drug level increased 232.73 9.55 256 427003 11468 110150572
Nausea 229.52 9.55 3379 423880 1232311 108929729
Decreased appetite 227.90 9.55 1004 426255 474842 109687198
Product dose omission issue 227.68 9.55 572 426687 321210 109840830
Fall 225.20 9.55 1387 425872 602095 109559945
Human herpesvirus 6 infection 221.63 9.55 192 427067 6389 110155651
Acute graft versus host disease in skin 221.01 9.55 239 427020 10501 110151539
Cardiac failure congestive 220.52 9.55 157 427102 150843 110011197
Delayed graft function 220.48 9.55 160 427099 4097 110157943
Varicella zoster virus infection 210.86 9.55 184 427075 6184 110155856
Systemic candida 210.60 9.55 225 427034 9749 110152291
Parvovirus B19 infection 210.56 9.55 134 427125 2747 110159293
Discomfort 209.82 9.55 315 426944 214392 109947648
Dehydration 207.88 9.55 484 426775 279027 109883013
Acute respiratory distress syndrome 205.99 9.55 559 426700 52639 110109401
Constipation 201.14 9.55 708 426551 357078 109804962
Herpes simplex 197.50 9.55 273 426986 15491 110146549
Cystitis haemorrhagic 194.42 9.55 238 427021 11971 110150069
Heart rate decreased 190.12 9.55 727 426532 82029 110080011
Myopathy 188.73 9.55 343 426916 24617 110137423
Urine abnormality 184.70 9.55 201 427058 8895 110153145
Hospitalisation 183.29 9.55 168 427091 142325 110019715
Dizziness 183.14 9.55 1769 425490 696424 109465616
Acinetobacter infection 182.12 9.55 133 427126 3440 110158600
Blood pressure diastolic decreased 182.04 9.55 418 426841 35467 110126573
Graft versus host disease in skin 181.02 9.55 190 427069 8064 110153976
Hypogammaglobulinaemia 178.04 9.55 296 426963 19780 110142260
Lymphopenia 178.00 9.55 444 426815 39726 110122314
Pulmonary mucormycosis 177.67 9.55 108 427151 2035 110160005
Polyomavirus viraemia 176.36 9.55 129 427130 3345 110158695
Pharyngeal paraesthesia 175.64 9.55 138 427121 3994 110158046
Cushingoid 174.79 9.55 221 427038 11491 110150549
Diarrhoea 174.44 9.55 3228 424031 1136277 109025763
Alopecia 173.10 9.55 772 426487 363981 109798059
Abdominal discomfort 169.16 9.55 864 426395 392994 109769046
Swelling 168.99 9.55 739 426520 350302 109811738
Infection reactivation 166.40 9.55 133 427126 3948 110158092
Rheumatoid arthritis 166.24 9.55 1830 425429 297783 109864257
COVID-19 pneumonia 166.11 9.55 412 426847 36731 110125309
Lymphocyte count decreased 166.02 9.55 543 426716 56700 110105340
Synovitis 165.93 9.55 525 426734 273567 109888473
Contusion 165.65 9.55 414 426845 232947 109929093
Confusional state 165.07 9.55 1096 426163 467584 109694456
Swollen joint count increased 162.26 9.55 60 427199 83601 110078439
Oedema peripheral 161.79 9.55 686 426573 327974 109834066
Disseminated intravascular coagulation 158.01 9.55 432 426827 40854 110121186
Wound 156.42 9.55 429 426830 234008 109928032
Suicide attempt 155.61 9.55 104 427155 103290 110058750
Renal transplant failure 155.60 9.55 108 427151 2572 110159468
Drug resistance 153.06 9.55 523 426736 55851 110106189
Wrong technique in product usage process 152.79 9.55 73 427186 87275 110074765
White blood cells urine positive 152.32 9.55 166 427093 7358 110154682
Road traffic accident 151.19 9.55 116 427143 107282 110054758
Cytomegalovirus test positive 150.82 9.55 160 427099 6876 110155164
Stenotrophomonas infection 150.70 9.55 147 427112 5711 110156329
Red blood cells urine positive 150.31 9.55 139 427120 5046 110156994
Myocardial infarction 149.80 9.55 324 426935 191759 109970281
Leukopenia 148.14 9.55 1034 426225 147757 110014283
Liver transplant rejection 147.75 9.55 122 427137 3796 110158244
Osteonecrosis 146.42 9.55 370 426889 33371 110128669
Enterobacter infection 146.09 9.55 144 427115 5667 110156373
Disseminated mucormycosis 141.88 9.55 93 427166 2009 110160031
Lower limb fracture 139.60 9.55 58 427201 75290 110086750
Urine leukocyte esterase positive 138.84 9.55 116 427143 3670 110158370
Secondary immunodeficiency 136.81 9.55 126 427133 4550 110157490
Dyspnoea 136.49 9.55 3247 424012 1103625 109058415
Penicillium infection 136.02 9.55 61 427198 590 110161450
Acute graft versus host disease in intestine 134.87 9.55 136 427123 5503 110156537
Adverse event 134.42 9.55 133 427126 108676 110053364
Glossodynia 133.80 9.55 426 426833 221578 109940462
Hand deformity 133.30 9.55 417 426842 218089 109943951
Adverse drug reaction 130.43 9.55 129 427130 105430 110056610
Systemic mycosis 129.53 9.55 112 427147 3717 110158323
Overdose 129.07 9.55 466 426793 233328 109928712
Chronic allograft nephropathy 128.92 9.55 88 427171 2038 110160002
Hypoglycaemia 127.90 9.55 156 427103 115948 110046092
Contraindicated product administered 127.90 9.55 509 426750 247758 109914282
Venoocclusive disease 126.64 9.55 139 427120 6211 110155829
Wheezing 125.41 9.55 533 426726 254697 109907343
Cryptococcosis 124.38 9.55 119 427140 4512 110157528
Focal segmental glomerulosclerosis 123.82 9.55 113 427146 4032 110158008
JC virus infection 123.63 9.55 126 427133 5164 110156876
Chest pain 122.69 9.55 900 426359 375475 109786565
Nephropathy toxic 122.04 9.55 304 426955 27174 110134866
Drug intolerance 121.78 9.55 995 426264 405517 109756523
Injection site erythema 121.14 9.55 111 427148 94065 110067975
Mycobacterium chelonae infection 121.10 9.55 98 427161 2962 110159078
Deep vein thrombosis postoperative 121.06 9.55 39 427220 59252 110102788
Oedema 119.60 9.55 413 426846 209563 109952477
Ureaplasma infection 118.22 9.55 74 427185 1472 110160568
Arthropathy 118.20 9.55 640 426619 286882 109875158
Knee arthroplasty 117.13 9.55 52 427207 64896 110097144
Sedation 116.23 9.55 62 427197 69621 110092419
Therapy non-responder 116.10 9.55 1020 426239 156287 110005753
Bacterial sepsis 115.09 9.55 170 427089 10256 110151784
Pneumonia klebsiella 114.98 9.55 135 427124 6497 110155543
Acute graft versus host disease 114.33 9.55 190 427069 12691 110149349
Cytomegalovirus chorioretinitis 113.58 9.55 139 427120 6989 110155051
Pericarditis 113 9.55 449 426810 218665 109943375
Sepsis 111.60 9.55 1831 425428 325515 109836525
Syncope 111.59 9.55 404 426855 202132 109959908
Immunosuppressant drug level decreased 110.20 9.55 89 427170 2682 110159358
Full blood count abnormal 109.03 9.55 40 427219 56012 110106028
Fungal infection 107.51 9.55 435 426824 50371 110111669
Bacteraemia 107.06 9.55 384 426875 42006 110120034
Reversible cerebral vasoconstriction syndrome 106.93 9.55 111 427148 4650 110157390
Medication error 106.41 9.55 151 427108 105215 110056825
Cytomegalovirus enteritis 104.23 9.55 60 427199 1018 110161022
Peripheral swelling 103.50 9.55 1029 426230 403005 109759035
Orthostatic hypotension 103.28 9.55 64 427195 66185 110095855
Heart rate increased 103.23 9.55 927 426332 142907 110019133
Pneumocystis jirovecii infection 103.19 9.55 105 427154 4295 110157745
Diffuse alveolar damage 103.07 9.55 101 427158 3946 110158094
Acute graft versus host disease in liver 102.90 9.55 80 427179 2279 110159761
Accidental overdose 102.51 9.55 36 427223 51798 110110242
Pain 102.46 9.55 2858 424401 952097 109209943
Viral haemorrhagic cystitis 102.19 9.55 93 427166 3306 110158734
Hip arthroplasty 101.73 9.55 44 427215 55769 110106271
Malacoplakia 100.99 9.55 62 427197 1190 110160850
Sciatica 100.87 9.55 125 427134 92274 110069766
Rhabdomyolysis 100.72 9.55 195 427064 120206 110041834
Hyponatraemia 99.99 9.55 466 426793 217187 109944853
Systemic lupus erythematosus 99.17 9.55 576 426683 253762 109908278
Opportunistic infection 98.89 9.55 93 427166 3450 110158590
Device expulsion 98.50 9.55 5 427254 30886 110131154
Chorioretinopathy 98.31 9.55 77 427182 2218 110159822
Malignant neoplasm progression 98.30 9.55 345 426914 174222 109987818
Staphylococcal infection 98.00 9.55 531 426728 69413 110092627
Electric shock 97.63 9.55 70 427189 1758 110160282
Cerebrovascular accident 96.98 9.55 366 426893 180918 109981122
Malaise 96.96 9.55 1921 425338 669898 109492142
Adjustment disorder with depressed mood 96.71 9.55 25 427234 43858 110118182
Asthma 96.43 9.55 569 426690 249722 109912318
Corynebacterium infection 96.43 9.55 72 427187 1928 110160112
Duodenal ulcer perforation 96.21 9.55 357 426902 177343 109984697
Infective aneurysm 95.83 9.55 64 427195 1428 110160612
Perinephric abscess 95.61 9.55 42 427217 385 110161655
Central nervous system viral infection 95.23 9.55 39 427220 295 110161745
Accidental exposure to product 95.08 9.55 37 427222 49971 110112069
Stomatitis 95.01 9.55 632 426627 269610 109892430
Renal tubular atrophy 94.56 9.55 75 427184 2201 110159839
Urinary sediment present 93.83 9.55 78 427181 2450 110159590
Viraemia 92.78 9.55 96 427163 4006 110158034
Rectal haemorrhage 92.69 9.55 203 427056 119630 110042410
Herpes zoster 92.38 9.55 726 426533 107653 110054387
Coeliac disease 92.37 9.55 371 426888 42816 110119224
Intensive care unit acquired weakness 92.20 9.55 75 427184 2284 110159756
Crystal urine present 90.60 9.55 69 427190 1905 110160135
Premature delivery 90.10 9.55 292 426967 30340 110131700
Injection site bruising 89.41 9.55 43 427216 51220 110110820
Graft versus host disease in liver 89.31 9.55 75 427184 2390 110159650
Staphylococcal sepsis 89.28 9.55 204 427055 17250 110144790
Large intestine perforation 89.13 9.55 198 427061 16431 110145609
Pneumonia bacterial 89.00 9.55 263 426996 25998 110136042
Epstein-Barr virus associated lymphoproliferative disorder 88.71 9.55 101 427158 4701 110157339
Transplant failure 88.36 9.55 109 427150 5526 110156514
International normalised ratio increased 87.97 9.55 124 427135 86648 110075392
Liver disorder 87.76 9.55 270 426989 141973 110020067
Helicobacter infection 87.37 9.55 383 426876 181494 109980546
Pneumonia cryptococcal 87.30 9.55 75 427184 2467 110159573
Glomerulonephritis 86.56 9.55 99 427160 4631 110157409
Therapy partial responder 86.27 9.55 327 426932 36734 110125306
Pemphigus 85.22 9.55 483 426776 214087 109947953
Back injury 85.00 9.55 386 426873 47013 110115027
Poisoning deliberate 84.80 9.55 4 427255 26327 110135713
Lupus nephritis 84.63 9.55 97 427162 4548 110157492
Finger deformity 84.62 9.55 301 426958 32791 110129249
Hyperglycaemia 83.88 9.55 590 426669 84500 110077540
Proteinuria 83.38 9.55 341 426918 39677 110122363
Onychomycosis 83.20 9.55 332 426927 38199 110123841
Asthenia 81.42 9.55 2033 425226 686966 109475074
Epstein-Barr viraemia 81.38 9.55 84 427175 3495 110158545
Granulomatosis with polyangiitis 81.33 9.55 83 427176 3407 110158633
Autoimmune disorder 80.92 9.55 80 427179 65403 110096637
Serotonin syndrome 80.59 9.55 66 427193 59087 110102953
Disseminated cryptococcosis 80.47 9.55 73 427186 2584 110159456
Swollen tongue 80.21 9.55 69 427190 60293 110101747
Incorrect route of product administration 79.47 9.55 78 427181 63983 110098057
Scedosporium infection 79.33 9.55 70 427189 2388 110159652
Amnesia 78.72 9.55 182 427077 105226 110056814
Intervertebral discitis 78.64 9.55 115 427144 6875 110155165
Necrotising retinitis 78.17 9.55 58 427201 1538 110160502
Injection site swelling 78.08 9.55 74 427185 61716 110100324
Chronic graft versus host disease 77.99 9.55 135 427124 9322 110152718
Frequent bowel movements 77.49 9.55 97 427162 71293 110090747
Pregnancy 77.32 9.55 51 427208 51016 110111024
Depressed level of consciousness 76.70 9.55 203 427056 112075 110049965
Bacterial test 76.36 9.55 51 427208 1138 110160902
Heart transplant rejection 76.35 9.55 63 427196 1958 110160082
Pneumonia acinetobacter 76.34 9.55 35 427224 358 110161682
Immunosuppression 76.27 9.55 194 427065 17565 110144475
Neuroleptic malignant syndrome 75.83 9.55 19 427240 34040 110128000
Epstein-Barr virus infection reactivation 75.62 9.55 86 427173 3998 110158042
Obstructive airways disorder 75.60 9.55 42 427217 46107 110115933
Kidney fibrosis 75.47 9.55 89 427170 4303 110157737
Coronary artery disease 75.13 9.55 100 427159 71590 110090450
Encephalitis 74.97 9.55 200 427059 18639 110143401
Muscle injury 74.84 9.55 285 426974 140522 110021518
Pathogen resistance 74.81 9.55 192 427067 17480 110144560
Mycobacterium abscessus infection 74.73 9.55 58 427201 1648 110160392
Anti-cyclic citrullinated peptide antibody positive 74.25 9.55 406 426853 181578 109980462
Rhinocerebral mucormycosis 74.01 9.55 55 427204 1462 110160578
Condition aggravated 73.58 9.55 3507 423752 731329 109430711
Aplastic anaemia 73.57 9.55 234 427025 24074 110137966
Disseminated tuberculosis 73.48 9.55 95 427164 5051 110156989
Herpes virus infection 73.45 9.55 125 427134 8513 110153527
Prescribed underdose 73.44 9.55 86 427173 65088 110096952
Hepatic cirrhosis 73.28 9.55 92 427167 67534 110094506
Onychomadesis 73.23 9.55 360 426899 45303 110116737
C-reactive protein abnormal 73.22 9.55 256 427003 129439 110032601
Transient ischaemic attack 72.56 9.55 84 427175 63898 110098142
Dry skin 72.51 9.55 196 427063 107457 110054583
Pleocytosis 72.03 9.55 57 427202 1667 110160373
Thrombocytopenia 71.99 9.55 1811 425448 347074 109814966
Intentional product misuse 71.94 9.55 267 426992 132637 110029403
Nightmare 71.85 9.55 30 427229 38833 110123207
Central nervous system infection 71.80 9.55 57 427202 1675 110160365
Irritable bowel syndrome 71.68 9.55 358 426901 163857 109998183
Graft loss 71.26 9.55 51 427208 1277 110160763
Disseminated aspergillosis 70.95 9.55 66 427193 2414 110159626
Device malfunction 70.65 9.55 8 427251 25550 110136490
Disseminated varicella zoster virus infection 70.59 9.55 50 427209 1231 110160809
Gastroenteritis norovirus 70.21 9.55 78 427181 3533 110158507
Loss of personal independence in daily activities 70.19 9.55 319 426940 149701 110012339
Delirium 70.03 9.55 276 426983 134749 110027291
Human herpesvirus 8 infection 70.01 9.55 58 427201 1813 110160227
Aplasia 69.70 9.55 116 427143 7757 110154283
Demyelination 69.29 9.55 128 427131 9301 110152739
Hypersensitivity 68.35 9.55 1123 426136 402875 109759165
Osteomyelitis fungal 67.66 9.55 33 427226 392 110161648
Pruritus 67.58 9.55 1720 425539 579840 109582200
Gastroenteritis rotavirus 67.36 9.55 37 427222 571 110161469
Staphylococcal bacteraemia 67.25 9.55 178 427081 16510 110145530
Fungal skin infection 67.14 9.55 109 427150 7140 110154900
Brain abscess 67.06 9.55 105 427154 6669 110155371
Loss of consciousness 67.03 9.55 463 426796 195843 109966197
Pseudomonal sepsis 66.73 9.55 123 427136 8923 110153117
Bone erosion 66.65 9.55 49 427210 46322 110115718
Lung abscess 66.12 9.55 89 427170 4923 110157117
Suicidal ideation 65.57 9.55 168 427091 93769 110068271
Blister 65.55 9.55 562 426697 226814 109935226
Diffuse large B-cell lymphoma 65.52 9.55 171 427088 15727 110146313
Symptom masked 65.26 9.55 56 427203 1839 110160201
Protein urine present 65.26 9.55 140 427119 11344 110150696
X-ray abnormal 64.92 9.55 33 427226 38084 110123956
Pulmonary tuberculosis 64.59 9.55 122 427137 9017 110153023
Blood pressure diastolic increased 64.35 9.55 189 427070 18618 110143422
Atrial fibrillation 64.25 9.55 572 426687 229070 109932970
Renal impairment 64.13 9.55 1054 426205 187391 109974649
Herpes simplex pneumonia 64.03 9.55 31 427228 362 110161678
Cytomegalovirus enterocolitis 63.91 9.55 60 427199 2221 110159819
Phaeohyphomycosis 63.86 9.55 53 427206 1661 110160379
Immune thrombocytopenia 63.09 9.55 211 427048 22283 110139757
Neutrophil percentage increased 62.92 9.55 86 427173 4827 110157213
Pneumonia fungal 62.15 9.55 160 427099 14594 110147446
Enterocolitis viral 61.97 9.55 40 427219 841 110161199
Unresponsive to stimuli 61.88 9.55 94 427165 63696 110098344
C-reactive protein 61.83 9.55 20 427239 30311 110131729
Rash 61.72 9.55 2569 424690 818395 109343645
Cerebral aspergillosis 61.54 9.55 59 427200 2243 110159797
Multiple-drug resistance 61.50 9.55 149 427110 13086 110148954
Urine ketone body present 61.28 9.55 75 427184 3771 110158269
Sinusitis 61.23 9.55 793 426466 295895 109866145
Fungaemia 61.17 9.55 95 427164 5991 110156049
Product prescribing error 60.83 9.55 65 427194 51266 110110774
Lethargy 60.33 9.55 174 427085 93402 110068638
Incorrect dose administered 60.25 9.55 202 427057 103439 110058601
Urine analysis abnormal 60.23 9.55 101 427158 6796 110155244
Tuberculosis 60.23 9.55 178 427081 17596 110144444
Bacterial infection 60.15 9.55 343 426916 45693 110116347
Pulmonary alveolar haemorrhage 60.09 9.55 193 427066 19957 110142083
Mycoplasma infection 60.09 9.55 47 427212 1351 110160689
Lower respiratory tract infection 59.78 9.55 625 426634 242481 109919559
Blood immunoglobulin G decreased 59.53 9.55 88 427171 5312 110156728
Temperature regulation disorder 59.18 9.55 144 427115 12682 110149358
Shock haemorrhagic 59.01 9.55 235 427024 27012 110135028
Plasma cell myeloma 58.90 9.55 95 427164 62841 110099199
Cytomegalovirus gastrointestinal infection 58.78 9.55 36 427223 688 110161352
Gait disturbance 58.75 9.55 740 426519 277468 109884572
Transplant dysfunction 58.64 9.55 111 427148 8217 110153823
Cryptococcal meningoencephalitis 58.27 9.55 29 427230 361 110161679
Skin striae 58.06 9.55 56 427203 2145 110159895
Cytomegalovirus oesophagitis 57.87 9.55 40 427219 946 110161094
Psoriatic arthropathy 57.76 9.55 484 426775 196277 109965763
Abdominal pain 57.51 9.55 1525 425734 511464 109650576
Pneumonia pseudomonal 57.43 9.55 104 427155 7442 110154598
Intentional self-injury 57.19 9.55 37 427222 37392 110124648
Renal tubular necrosis 56.76 9.55 251 427008 30224 110131816
Ureteric stenosis 56.64 9.55 48 427211 1549 110160491
Erythema 56.64 9.55 1501 425758 289946 109872094
Drug-induced liver injury 56.58 9.55 711 426548 119356 110042684
Fibromyalgia 56.44 9.55 407 426852 170502 109991538
Drug tolerance decreased 56.43 9.55 18 427241 27522 110134518
Lymphocyte percentage decreased 56.35 9.55 85 427174 5225 110156815
Injection site pruritus 56.31 9.55 69 427190 51189 110110851
Hypertension 56.10 9.55 2458 424801 507626 109654414
Multiple sclerosis 55.94 9.55 222 427037 25476 110136564
Candida sepsis 55.92 9.55 63 427196 2898 110159142
Device issue 55.75 9.55 32 427227 34503 110127537
General physical health deterioration 55.69 9.55 1235 426024 424060 109737980
Human polyomavirus infection 55.54 9.55 50 427209 1752 110160288
Gastrointestinal mucormycosis 55.49 9.55 35 427224 706 110161334
Substance-induced psychotic disorder 54.98 9.55 85 427174 5339 110156701
Encephalitis cytomegalovirus 54.97 9.55 51 427208 1859 110160181
Peritonitis 54.39 9.55 260 426999 32347 110129693
Nephrotic syndrome 54.19 9.55 146 427113 13685 110148355
Prescribed overdose 54.19 9.55 166 427093 87415 110074625
Neutrophil count increased 54.01 9.55 271 426988 34381 110127659
Protothecosis 53.85 9.55 31 427228 526 110161514
C-reactive protein increased 53.81 9.55 1160 426099 216759 109945281
Therapeutic product effect decreased 53.79 9.55 644 426615 243672 109918368
Exostosis 53.57 9.55 59 427200 45897 110116143
Hepatitis 53.56 9.55 558 426701 89496 110072544
Listeriosis 53.37 9.55 60 427199 2754 110159286
Dislocation of vertebra 53.35 9.55 54 427205 43667 110118373
Somnolence 52.90 9.55 819 426440 296630 109865410
Blood urine present 52.42 9.55 209 427050 24036 110138004
Anxiety 52.34 9.55 978 426281 344100 109817940
Pneumonia necrotising 52.26 9.55 48 427211 1727 110160313
Pneumoretroperitoneum 52.24 9.55 22 427237 180 110161860
Escherichia urinary tract infection 52.07 9.55 159 427100 16003 110146037
Haemolytic uraemic syndrome 51.77 9.55 79 427180 4906 110157134
Hypophagia 51.57 9.55 77 427182 52549 110109491
Dural arteriovenous fistula 51.53 9.55 18 427241 82 110161958
Renal graft infection 51.45 9.55 34 427225 745 110161295
Electrocardiogram QT prolonged 51.38 9.55 231 427028 108729 110053311
Pulmonary haemorrhage 51.26 9.55 160 427099 16296 110145744
Cutaneous mucormycosis 50.99 9.55 33 427226 697 110161343
Glomerulosclerosis 50.75 9.55 41 427218 1236 110160804
Fusarium infection 50.71 9.55 58 427201 2713 110159327
Haemoglobin urine present 50.49 9.55 36 427223 896 110161144
Hallucination 50.29 9.55 211 427048 101221 110060819
Immune reconstitution inflammatory syndrome 49.84 9.55 157 427102 16069 110145971
Parvovirus infection 49.83 9.55 36 427223 915 110161125
Torsade de pointes 49.56 9.55 13 427246 22587 110139453
Pseudomonal bacteraemia 49.30 9.55 72 427187 4299 110157741
Device difficult to use 49.28 9.55 7 427252 18798 110143242
Cerebral fungal infection 49.15 9.55 32 427227 683 110161357
Respiratory arrest 49.11 9.55 94 427165 58205 110103835
Growth retardation 48.87 9.55 55 427204 2527 110159513
Serum sickness 48.86 9.55 72 427187 4334 110157706
Epstein-Barr virus associated lymphoma 48.86 9.55 45 427214 1625 110160415
Prostate cancer 48.84 9.55 44 427215 37597 110124443
Injection site mass 48.83 9.55 17 427242 24596 110137444
Hepatitis B 48.78 9.55 112 427147 9500 110152540
Dyskinesia 48.76 9.55 77 427182 51369 110110671
Oral pruritus 48.52 9.55 62 427197 3258 110158782
Culture urine positive 48.39 9.55 75 427184 4721 110157319
Liver abscess 48.24 9.55 98 427161 7641 110154399
Intestinal perforation 48.09 9.55 184 427075 20760 110141280
Product label confusion 47.84 9.55 194 427065 22483 110139557
Haemolytic anaemia 47.39 9.55 183 427076 20737 110141303
Full blood count decreased 47.34 9.55 33 427226 32066 110129974
Abdominal abscess 47.25 9.55 105 427154 8714 110153326
Subcutaneous emphysema 47.14 9.55 54 427205 2530 110159510
Poisoning 46.94 9.55 27 427232 29078 110132962
Disseminated blastomycosis 46.91 9.55 27 427232 458 110161582
Therapy interrupted 46.81 9.55 75 427184 49747 110112293
Cytomegalovirus hepatitis 46.80 9.55 34 427225 872 110161168
Quadriplegia 46.57 9.55 68 427191 4059 110157981
Rheumatic fever 46.48 9.55 280 426979 122299 110039741
Oesophageal candidiasis 46.45 9.55 123 427136 11411 110150629
Proteus infection 46.44 9.55 56 427203 2772 110159268
Sedation complication 46.34 9.55 10 427249 19845 110142195
Necrotising herpetic retinopathy 46.33 9.55 20 427239 175 110161865
Blastomycosis 46.30 9.55 37 427222 1098 110160942
Apoptosis 46.29 9.55 31 427228 695 110161345
Injection site haemorrhage 46.06 9.55 36 427223 32992 110129048
Obliterative bronchiolitis 45.93 9.55 64 427195 3659 110158381
Central nervous system fungal infection 45.67 9.55 29 427230 592 110161448
Multiple sclerosis relapse 45.28 9.55 341 426918 49899 110112141
Enterococcus test positive 45.25 9.55 56 427203 2848 110159192
Red blood cell sedimentation rate abnormal 45.18 9.55 19 427240 24490 110137550
Status epilepticus 45.11 9.55 241 427018 31330 110130710
Pneumothorax 44.86 9.55 261 426998 35024 110127016
Mobility decreased 44.52 9.55 647 426612 236775 109925265
Device leakage 44.42 9.55 5 427254 16043 110145997
Intra-abdominal pressure increased 44.41 9.55 24 427235 358 110161682
Osmotic demyelination syndrome 44.37 9.55 47 427212 2016 110160024
Urinary tract infection bacterial 44.30 9.55 97 427162 7970 110154070
Feeling abnormal 44.25 9.55 465 426794 180246 109981794
Oral herpes 44.01 9.55 264 426995 35816 110126224
Musculoskeletal pain 43.98 9.55 473 426786 182550 109979490
Partial seizures 43.67 9.55 119 427140 11230 110150810
Device dislocation 43.65 9.55 35 427224 31669 110130371
Aplasia pure red cell 43.62 9.55 107 427152 9471 110152569
Cardiac disorder 43.43 9.55 150 427109 76130 110085910
Post-traumatic stress disorder 42.88 9.55 85 427174 6511 110155529
Feeding intolerance 42.85 9.55 36 427223 1148 110160892
Vasculitis 42.82 9.55 261 426998 35612 110126428
Anti-cyclic citrullinated peptide antibody 42.81 9.55 12 427247 19952 110142088
Encephalitis autoimmune 42.56 9.55 60 427199 3468 110158572
Myalgia 42.40 9.55 604 426655 221777 109940263
Neutrophil count decreased 42.39 9.55 283 426976 120658 110041382
Granulocyte count increased 42.34 9.55 45 427214 1938 110160102
Pyelonephritis fungal 42.19 9.55 22 427237 304 110161736
Toxoplasmosis 41.94 9.55 57 427202 3182 110158858
Escherichia sepsis 41.84 9.55 110 427149 10162 110151878
Blood calcium decreased 41.80 9.55 46 427213 35799 110126241
Blood potassium increased 41.80 9.55 40 427219 33209 110128831
Coma 41.72 9.55 275 426984 117594 110044446
Serum ferritin increased 41.44 9.55 120 427139 11727 110150313
Product storage error 41.43 9.55 16 427243 21712 110140328
West Nile viral infection 41.28 9.55 37 427222 1289 110160751
Unevaluable event 41.27 9.55 106 427153 59121 110102919
Disseminated strongyloidiasis 41.24 9.55 27 427232 582 110161458
Lupus vulgaris 41.17 9.55 42 427217 33841 110128199
Respiratory rate increased 41.11 9.55 199 427060 24884 110137156
B-lymphocyte count decreased 41.01 9.55 45 427214 2010 110160030
Mycotic endophthalmitis 40.94 9.55 24 427235 422 110161618
Tardive dyskinesia 40.88 9.55 3 427256 13576 110148464
Pancytopenia 40.84 9.55 1080 426179 208533 109953507
Neuromyelitis optica spectrum disorder 40.82 9.55 39 427220 1476 110160564
Histoplasmosis disseminated 40.79 9.55 62 427197 3837 110158203
Immunodeficiency 40.46 9.55 273 426986 38565 110123475
Drug interaction 40.35 9.55 1552 425707 498631 109663409
Trichodysplasia spinulosa 40.23 9.55 33 427226 1017 110161023
Herpes simplex reactivation 39.95 9.55 38 427221 1430 110160610
Infective pulmonary exacerbation of cystic fibrosis 39.90 9.55 5 427254 14766 110147274
Sleep disorder 39.85 9.55 534 426725 198110 109963930
Pneumoperitoneum 39.78 9.55 62 427197 3922 110158118
Amoebic colitis 39.65 9.55 16 427243 116 110161924
Abdominal infection 39.62 9.55 68 427191 4663 110157377
Visceral leishmaniasis 39.54 9.55 41 427218 1715 110160325
Blood immunoglobulin M decreased 39.53 9.55 44 427215 1997 110160043
Disseminated varicella zoster vaccine virus infection 39.36 9.55 17 427242 149 110161891
Haemodynamic instability 39.27 9.55 184 427075 22704 110139336
Palmar-plantar erythrodysaesthesia syndrome 39.26 9.55 61 427198 40964 110121076
Female genital tract fistula 39.21 9.55 8 427251 16511 110145529
Alternaria infection 39.18 9.55 32 427227 980 110161060
Cardio-respiratory arrest 39.14 9.55 274 426985 115562 110046478
Polychondritis 39.02 9.55 31 427228 912 110161128
Steroid withdrawal syndrome 38.96 9.55 31 427228 914 110161126
Hyperkalaemia 38.96 9.55 336 426923 135460 110026580
Joint swelling 38.88 9.55 1360 425899 441485 109720555
Alveolitis 38.76 9.55 65 427194 4374 110157666
Bacillus infection 38.74 9.55 39 427220 1575 110160465
Segmental diverticular colitis 38.59 9.55 17 427242 157 110161883
Necrosis ischaemic 38.56 9.55 36 427223 1323 110160717
Monocyte count increased 38.45 9.55 126 427133 13167 110148873
Atypical haemolytic uraemic syndrome 38.41 9.55 38 427221 1502 110160538
Respiratory distress 38.27 9.55 421 426838 68453 110093587
Underdose 38.23 9.55 122 427137 63432 110098608
Stress 38.19 9.55 244 427015 105104 110056936
Oliguria 38.09 9.55 158 427101 18499 110143541
Therapy cessation 38.07 9.55 72 427187 44785 110117255
Disease progression 37.86 9.55 1222 426037 242812 109919228
Dermatomyositis 37.78 9.55 64 427195 4342 110157698
Kaposi's sarcoma 37.76 9.55 27 427232 675 110161365
Reticulocytosis 37.65 9.55 26 427233 614 110161426
Herpes zoster meningoencephalitis 37.42 9.55 32 427227 1046 110160994
Lip swelling 37.41 9.55 88 427171 50579 110111461
Post cholecystectomy syndrome 37.39 9.55 29 427230 823 110161217
Flatulence 37.37 9.55 92 427167 52057 110109983
Incision site pain 37.35 9.55 53 427206 3082 110158958
Eczema 37.33 9.55 148 427111 72145 110089895
Bacterial test positive 37.27 9.55 90 427169 7887 110154153
Enterococcal bacteraemia 37.20 9.55 64 427195 4397 110157643
Herpes simplex hepatitis 37.14 9.55 28 427231 761 110161279
CSF oligoclonal band present 37.12 9.55 23 427236 449 110161591
Abscess bacterial 37.06 9.55 30 427229 907 110161133
Foot deformity 36.76 9.55 83 427176 48397 110113643
Breast cancer stage II 36.73 9.55 31 427228 27344 110134696
Meningoencephalitis viral 36.51 9.55 24 427235 521 110161519
Thrombosis 36.24 9.55 258 427001 108404 110053636
Febrile neutropenia 36.16 9.55 939 426320 315828 109846212
Human bocavirus infection 36.16 9.55 32 427227 1096 110160944
Acute respiratory failure 36.02 9.55 447 426812 74813 110087227
Lupus-like syndrome 35.93 9.55 64 427195 40728 110121312
Red cell distribution width increased 35.88 9.55 149 427110 17453 110144587
Cataract 35.88 9.55 467 426792 79018 110083022
Pedal pulse abnormal 35.76 9.55 18 427241 230 110161810
Central nervous system lymphoma 35.58 9.55 51 427208 2993 110159047
Arteriosclerosis coronary artery 35.51 9.55 27 427232 25091 110136949
Infectious pleural effusion 35.44 9.55 66 427193 4825 110157215
Plasmodium falciparum infection 35.21 9.55 16 427243 160 110161880
Klebsiella sepsis 35.18 9.55 60 427199 4093 110157947
Body temperature decreased 35.17 9.55 254 427005 36681 110125359
Macular degeneration 35.06 9.55 20 427239 21639 110140401
Cardiac failure 34.92 9.55 512 426747 187114 109974926
Pain in extremity 34.91 9.55 1532 425727 485586 109676454
Pyelonephritis 34.89 9.55 191 427068 25059 110136981
Renal tubular injury 34.77 9.55 51 427208 3057 110158983
Neurological decompensation 34.71 9.55 80 427179 6803 110155237
Leukocytosis 34.63 9.55 339 426920 53489 110108551
Folliculitis 34.61 9.55 448 426811 167205 109994835
Idiopathic pneumonia syndrome 34.24 9.55 28 427231 859 110161181
Needle issue 34.24 9.55 13 427246 17827 110144213
Diabetes mellitus 34.22 9.55 557 426702 98824 110063216
Blood immunoglobulin A increased 34.22 9.55 36 427223 1532 110160508
Rash pruritic 34.11 9.55 230 427029 97839 110064201
SARS-CoV-2 viraemia 34.10 9.55 15 427244 138 110161902
Empyema 34.09 9.55 70 427189 5500 110156540
Gastroduodenal ulcer 34.06 9.55 29 427230 942 110161098
Blood parathyroid hormone decreased 34.00 9.55 5 427254 13084 110148956
Viral sepsis 33.92 9.55 17 427242 215 110161825
Electrocardiogram QRS complex prolonged 33.77 9.55 5 427254 13016 110149024
Insomnia 33.60 9.55 1099 426160 359491 109802549
Fungal endocarditis 33.56 9.55 27 427232 809 110161231
Hypoalbuminaemia 33.44 9.55 209 427050 28765 110133275
Cytokine release syndrome 33.40 9.55 417 426842 69889 110092151
White blood cell count decreased 33.26 9.55 655 426604 228735 109933305
Flushing 33.13 9.55 579 426680 104157 110057883
Meningitis fungal 33.13 9.55 19 427240 320 110161720
Blood thyroid stimulating hormone decreased 33.11 9.55 81 427178 7158 110154882
Hepatic artery aneurysm 33.09 9.55 13 427246 87 110161953
Vaginal flatulence 33.07 9.55 4 427255 12140 110149900
Type I hypersensitivity 33.01 9.55 75 427184 6318 110155722
Hepatic artery thrombosis 32.94 9.55 20 427239 376 110161664
Cerebral venous thrombosis 32.90 9.55 51 427208 3211 110158829
Creatinine renal clearance decreased 32.74 9.55 22 427237 21793 110140247
Aggression 32.66 9.55 118 427141 59092 110102948
Febrile bone marrow aplasia 32.64 9.55 144 427115 17321 110144719
Extrapyramidal disorder 32.62 9.55 38 427221 28829 110133211
Tremor 32.58 9.55 567 426692 201665 109960375
Urinary tract candidiasis 32.56 9.55 31 427228 1168 110160872
Injury 32.55 9.55 485 426774 176780 109985260
Mycobacterial infection 32.51 9.55 60 427199 4357 110157683
Vesicoureteric reflux 32.45 9.55 16 427243 195 110161845
Orchitis 32.44 9.55 38 427221 1824 110160216
Lymphocele 32.29 9.55 38 427221 1833 110160207
Laboratory test abnormal 32.19 9.55 77 427182 44002 110118038
Impaired healing 32.19 9.55 550 426709 196167 109965873
Respiratory depression 32.16 9.55 46 427213 31955 110130085
Muscle spasms 32.15 9.55 823 426436 277334 109884706
Laryngeal stenosis 32.13 9.55 33 427226 1365 110160675
Osteonecrosis of jaw 31.90 9.55 88 427171 47929 110114111
Anti-neutrophil cytoplasmic antibody positive vasculitis 31.89 9.55 67 427192 5350 110156690
Impaired work ability 31.81 9.55 33 427226 26386 110135654
New onset diabetes after transplantation 31.81 9.55 20 427239 401 110161639
Hepatic infarction 31.79 9.55 28 427231 953 110161087
Enterovirus infection 31.78 9.55 46 427213 2724 110159316
Lung neoplasm malignant 31.74 9.55 51 427208 33791 110128249
Meningitis cryptococcal 31.72 9.55 62 427197 4700 110157340
Coordination abnormal 31.68 9.55 186 427073 25042 110136998
Labelled drug-drug interaction medication error 31.60 9.55 40 427219 29262 110132778
Joint injury 31.54 9.55 67 427192 39927 110122113
Monkeypox 31.44 9.55 19 427240 354 110161686
Splenic embolism 31.41 9.55 16 427243 210 110161830
Pulmonary fibrosis 31.31 9.55 248 427011 101794 110060246
Hypokalaemia 31.19 9.55 506 426753 181942 109980098
Anaemia 31.17 9.55 1762 425497 545324 109616716
Serratia infection 31.16 9.55 41 427218 2218 110159822
Throat tightness 31.14 9.55 229 427030 33260 110128780
Pneumocephalus 31.12 9.55 21 427238 477 110161563
Food allergy 31.08 9.55 156 427103 19792 110142248
Viral infection 31.00 9.55 328 426931 52811 110109229
American trypanosomiasis 30.96 9.55 23 427236 611 110161429
Rheumatoid factor increased 30.81 9.55 43 427216 2462 110159578
Optic neuritis 30.76 9.55 104 427155 11043 110150997
Bone pain 30.75 9.55 138 427121 64995 110097045
Pancreatitis 30.74 9.55 223 427036 93310 110068730
Superinfection bacterial 30.71 9.55 42 427217 2359 110159681
Passenger lymphocyte syndrome 30.70 9.55 15 427244 179 110161861
Drug withdrawal syndrome 30.64 9.55 63 427196 37991 110124049
Sideroblastic anaemia 30.63 9.55 20 427239 429 110161611
Akathisia 30.39 9.55 14 427245 17099 110144941
Graft complication 30.24 9.55 29 427230 1103 110160937
Spinal cord abscess 30.17 9.55 23 427236 636 110161404
Granuloma skin 30.04 9.55 4 427255 11279 110150761
Musculoskeletal stiffness 29.97 9.55 837 426422 278985 109883055
Nitrite urine present 29.93 9.55 30 427229 1205 110160835
Hepatic enzyme increased 29.66 9.55 979 426280 319913 109842127
Tularaemia 29.64 9.55 15 427244 194 110161846
Product dispensing error 29.60 9.55 13 427246 16332 110145708
Nephritis 29.58 9.55 70 427189 6056 110155984
Alveolar proteinosis 29.56 9.55 33 427226 1503 110160537
Hepatic necrosis 29.56 9.55 95 427164 9827 110152213
Chronic sinusitis 29.46 9.55 32 427227 25052 110136988
Autoimmune thyroiditis 29.43 9.55 72 427187 6362 110155678
Citrobacter infection 29.24 9.55 31 427228 1331 110160709
Restlessness 29.16 9.55 115 427144 56144 110105896
Jaundice cholestatic 29.14 9.55 10 427249 14598 110147442
Dystonia 29.13 9.55 34 427225 25771 110136269
Pneumonia 29.12 9.55 3839 423420 872875 109289165
Lip dry 28.99 9.55 247 427012 99836 110062204
Metastases to liver 28.99 9.55 58 427201 35328 110126712
Joint dislocation 28.91 9.55 55 427204 34135 110127905
Blood cholesterol increased 28.84 9.55 521 426738 184264 109977776
Clostridium difficile colitis 28.80 9.55 277 426982 43501 110118539
Post procedural bile leak 28.72 9.55 19 427240 417 110161623
Parkinsonism 28.71 9.55 26 427233 22161 110139879
Aphthous ulcer 28.62 9.55 159 427100 20977 110141063
Dysgeusia 28.60 9.55 156 427103 69829 110092211
Oesophageal carcinoma 28.59 9.55 5 427254 11519 110150521
Dementia 28.53 9.55 49 427210 31624 110130416
Renal vein thrombosis 28.51 9.55 28 427231 1097 110160943
IgA nephropathy 28.42 9.55 47 427212 3126 110158914
Candida pneumonia 28.39 9.55 27 427232 1016 110161024
Salivary hypersecretion 28.32 9.55 16 427243 17405 110144635
Lip pruritus 28.22 9.55 30 427229 1292 110160748
Microscopic polyangiitis 28.22 9.55 20 427239 493 110161547
Smear cervix abnormal 28.19 9.55 43 427216 2669 110159371
Respiratory tract infection fungal 28.19 9.55 30 427229 1294 110160746
Specific gravity urine decreased 28.13 9.55 25 427234 861 110161179
Parosmia 28.12 9.55 8 427251 13172 110148868
Limbic encephalitis 28.08 9.55 24 427235 784 110161256
Swelling face 28.03 9.55 225 427034 92096 110069944
Myoclonus 27.97 9.55 53 427206 32945 110129095
Bronchopleural fistula 27.96 9.55 25 427234 868 110161172
Staphylococcal mediastinitis 27.88 9.55 10 427249 50 110161990
Systemic inflammatory response syndrome 27.85 9.55 112 427147 12931 110149109
Acute kidney injury 27.78 9.55 2096 425163 633334 109528706
Adrenal insufficiency 27.78 9.55 268 426991 42122 110119918
Schizophrenia 27.74 9.55 26 427233 21800 110140240
Herpes simplex oesophagitis 27.65 9.55 19 427240 445 110161595
Cardiac infection 27.52 9.55 22 427237 653 110161387
Intestine transplant rejection 27.51 9.55 12 427247 108 110161932
Malacoplakia vesicae 27.46 9.55 11 427248 78 110161962
Hepatic failure 27.41 9.55 395 426864 68344 110093696
Sleep disorder due to a general medical condition 27.34 9.55 106 427153 52006 110110034
Neuropsychiatric lupus 27.33 9.55 15 427244 231 110161809
Encephalitis brain stem 27.30 9.55 17 427242 335 110161705
Chronic graft versus host disease in liver 27.28 9.55 25 427234 897 110161143
Scleroderma renal crisis 27.25 9.55 25 427234 898 110161142
Interstitial lung disease 27.16 9.55 718 426541 138616 110023424
Thyrotoxic periodic paralysis 26.94 9.55 14 427245 192 110161848
Blindness 26.93 9.55 236 427023 36123 110125917
Abnormal dreams 26.82 9.55 8 427251 12772 110149268
Sensory loss 26.81 9.55 158 427101 21299 110140741
Splenic infection viral 26.70 9.55 9 427250 36 110162004
Encephalopathy 26.69 9.55 451 426808 80604 110081436
Blood beta-D-glucan increased 26.68 9.55 23 427236 760 110161280
Cholelithiasis 26.68 9.55 140 427119 63282 110098758
Ecthyma 26.59 9.55 26 427233 1013 110161027
Neuropathy peripheral 26.57 9.55 510 426749 178767 109983273
Acute disseminated encephalomyelitis 26.55 9.55 18 427241 412 110161628
Poor venous access 26.53 9.55 174 427085 24348 110137692
Pericarditis fungal 26.48 9.55 16 427243 298 110161742
Varicella 26.38 9.55 50 427209 3705 110158335
Glomerular filtration rate increased 26.36 9.55 35 427224 1910 110160130
Cervicitis 26.34 9.55 16 427243 301 110161739
Sputum discoloured 26.32 9.55 42 427217 27903 110134137
Pancreas transplant rejection 26.27 9.55 17 427242 359 110161681
Renal haemorrhage 26.20 9.55 40 427219 2485 110159555
Blood brain barrier defect 26.19 9.55 14 427245 204 110161836
Dengue fever 26.16 9.55 29 427230 1310 110160730
Microsporidia infection 26.13 9.55 30 427229 1409 110160631
Emphysematous pyelonephritis 26.08 9.55 20 427239 558 110161482
Haematochezia 25.99 9.55 303 426956 115221 110046819
Toxic epidermal necrolysis 25.90 9.55 334 426925 56393 110105647
Enteritis 25.87 9.55 144 427115 19012 110143028
Acarodermatitis 25.86 9.55 35 427224 1946 110160094
Calcium ionised decreased 25.66 9.55 21 427238 645 110161395
Atypical mycobacterial pneumonia 25.66 9.55 16 427243 316 110161724
Adverse reaction 25.62 9.55 199 427060 29395 110132645
Red blood cells urine 25.61 9.55 21 427238 647 110161393
Rubella antibody positive 25.57 9.55 10 427249 66 110161974
Scopulariopsis infection 25.56 9.55 13 427246 170 110161870
Organising pneumonia 25.54 9.55 116 427143 14127 110147913
Angioedema 25.53 9.55 250 427009 98250 110063790
Chronic obstructive pulmonary disease 25.46 9.55 284 426975 108874 110053166
Coronavirus infection 25.42 9.55 88 427171 9457 110152583
Procedural pain 25.28 9.55 63 427196 35502 110126538
Microangiopathy 25.26 9.55 43 427216 2929 110159111
Pyomyositis 25.24 9.55 22 427237 738 110161302
Paraesthesia ear 25.22 9.55 19 427240 516 110161524
Hepatosplenomegaly 25.09 9.55 71 427188 6848 110155192
Donor specific antibody present 25.08 9.55 17 427242 389 110161651
Hydronephrosis 25.07 9.55 151 427108 20514 110141526
Lung transplant rejection 25.03 9.55 34 427225 1897 110160143
Rhinovirus infection 24.99 9.55 101 427158 11688 110150352
Adenoviral haemorrhagic cystitis 24.91 9.55 21 427238 673 110161367
Mitochondrial DNA mutation 24.90 9.55 18 427241 458 110161582
Head injury 24.89 9.55 84 427175 42933 110119107
Microangiopathic haemolytic anaemia 24.87 9.55 34 427225 1909 110160131
Complications of transplant surgery 24.77 9.55 22 427237 757 110161283
Epstein-Barr virus test positive 24.68 9.55 28 427231 1298 110160742
Blindness cortical 24.66 9.55 26 427233 1109 110160931
Disseminated cytomegaloviral infection 24.61 9.55 20 427239 608 110161432
Epilepsy 24.58 9.55 533 426726 99676 110062364
Dyspnoea exertional 24.56 9.55 270 426989 103790 110058250
Increased ventricular preload 24.56 9.55 8 427251 28 110162012
Graft infection 24.56 9.55 22 427237 766 110161274
Cryptosporidiosis infection 24.51 9.55 26 427233 1117 110160923
Alcohol poisoning 24.49 9.55 3 427256 9017 110153023
Urinary tract infection enterococcal 24.42 9.55 48 427211 3654 110158386
Abdominal pain upper 24.37 9.55 1101 426158 348010 109814030
Human ehrlichiosis 24.36 9.55 21 427238 694 110161346
Klebsiella test positive 24.33 9.55 38 427221 2408 110159632
Haemoglobin urine 24.28 9.55 12 427247 147 110161893
Visual impairment 24.26 9.55 369 426890 134059 110027981
Injection site warmth 24.23 9.55 19 427240 17386 110144654
Nosocomial infection 24.23 9.55 44 427215 3155 110158885
Blepharospasm 24.23 9.55 321 426938 54530 110107510
Angiosarcoma 24.18 9.55 19 427240 550 110161490
Aspergillosis oral 24.16 9.55 9 427250 51 110161989
Bone marrow failure 24.10 9.55 335 426924 57513 110104527
Memory impairment 24.03 9.55 578 426681 196366 109965674
Atypical mycobacterial infection 24.00 9.55 40 427219 2678 110159362
Hyperphosphataemia 23.94 9.55 17 427242 16364 110145676
Rhodococcus infection 23.92 9.55 18 427241 488 110161552
Hypocalcaemia 23.89 9.55 151 427108 65215 110096825
Epididymitis 23.89 9.55 38 427221 2446 110159594
Hepatitis E 23.79 9.55 53 427206 4406 110157634
Cerebral artery stenosis 23.78 9.55 23 427236 884 110161156
Hepatitis C 23.75 9.55 104 427155 12469 110149571
Venoocclusive liver disease 23.75 9.55 119 427140 15088 110146952
Joint stiffness 23.73 9.55 157 427102 67086 110094954
Monocytopenia 23.64 9.55 13 427246 201 110161839
Coronary artery dilatation 23.42 9.55 10 427249 85 110161955
Mycoplasma test positive 23.40 9.55 14 427245 256 110161784
Intentional product use issue 23.22 9.55 1176 426083 246730 109915310
Pulmonary hypertension 23.17 9.55 122 427137 55098 110106942
Factor XIII deficiency 23.12 9.55 10 427249 88 110161952
Nose deformity 23.07 9.55 14 427245 263 110161777
Fungal peritonitis 23.02 9.55 27 427232 1298 110160742
Bronchiolitis obliterans syndrome 22.97 9.55 20 427239 670 110161370
Hypocomplementaemia 22.97 9.55 15 427244 322 110161718
Urinary retention 22.96 9.55 166 427093 69517 110092523
Chromophobe renal cell carcinoma 22.94 9.55 9 427250 60 110161980
Meningitis aseptic 22.90 9.55 87 427172 9783 110152257
Mental status changes 22.89 9.55 186 427073 75936 110086104
Locked-in syndrome 22.84 9.55 23 427236 929 110161111
Drug hypersensitivity 22.76 9.55 1480 425779 452610 109709430
Influenza 22.75 9.55 833 426426 168268 109993772
Grip strength 22.61 9.55 4 427255 9137 110152903
CSF measles antibody positive 22.57 9.55 9 427250 63 110161977
Intracranial infection 22.53 9.55 15 427244 333 110161707
Aspartate aminotransferase 22.50 9.55 23 427236 946 110161094
Coma scale abnormal 22.49 9.55 5 427254 9721 110152319
Steroid dependence 22.48 9.55 78 427181 8391 110153649
Enthesopathy 22.48 9.55 10 427249 12468 110149572
Haemostasis 22.41 9.55 18 427241 538 110161502
Retinitis 22.41 9.55 58 427201 32269 110129771
Nail disorder 22.34 9.55 331 426928 57604 110104436
Thymus hypoplasia 22.32 9.55 30 427229 1657 110160383
Herpes oesophagitis 22.27 9.55 16 427243 403 110161637
Pneumonia adenoviral 22.22 9.55 19 427240 621 110161419
Type 2 diabetes mellitus 22.22 9.55 518 426741 176714 109985326
Band sensation 22.20 9.55 24 427235 1054 110160986
Central obesity 22.19 9.55 33 427226 2003 110160037
Coinfection 22.17 9.55 11 427248 136 110161904
Morganella infection 22.15 9.55 27 427232 1352 110160688
Intestinal obstruction 22.11 9.55 118 427141 53109 110108931
Bifidobacterium infection 22.10 9.55 10 427249 99 110161941
Pyuria 21.94 9.55 38 427221 2625 110159415
Neck pain 21.88 9.55 627 426632 122503 110039537
Atrioventricular block first degree 21.82 9.55 14 427245 14211 110147829
B-cell lymphoma 21.77 9.55 69 427190 7085 110154955
Liver function test increased 21.72 9.55 471 426788 88077 110073963
Leishmaniasis 21.64 9.55 17 427242 492 110161548
Heart rate irregular 21.63 9.55 215 427044 34059 110127981
Hepatic cancer 21.63 9.55 8 427251 11148 110150892
Nodular regenerative hyperplasia 21.57 9.55 29 427230 1602 110160438
Hypoproteinaemia 21.55 9.55 61 427198 5884 110156156
No adverse event 21.52 9.55 403 426856 73436 110088604
Herpes simplex viraemia 21.49 9.55 19 427240 650 110161390
Pyelonephritis acute 21.43 9.55 69 427190 7144 110154896
Pulmonary arterial hypertension 21.40 9.55 60 427199 32508 110129532
Product substitution issue 21.40 9.55 35 427224 23026 110139014
Bradycardia 21.36 9.55 448 426811 155069 110006971
Herpes simplex encephalitis 21.35 9.55 21 427238 824 110161216
Malacoplakia gastrointestinal 21.34 9.55 13 427246 246 110161794
Hypersomnia 21.31 9.55 48 427211 28013 110134027
Injection site urticaria 21.30 9.55 21 427238 17194 110144846
Skin irritation 21.26 9.55 19 427240 16300 110145740
Central nervous system vasculitis 21.25 9.55 29 427230 1625 110160415
Urine leukocyte esterase 21.25 9.55 12 427247 196 110161844
Norovirus infection 21.21 9.55 35 427224 2324 110159716
Respiratory symptom 21.21 9.55 16 427243 14929 110147111
Bronchial anastomosis complication 21.18 9.55 10 427249 110 110161930
Autoimmune hepatitis 21.14 9.55 113 427146 14691 110147349
Disability 21.13 9.55 54 427205 30169 110131871
Red blood cell schistocytes present 21.06 9.55 20 427239 751 110161289
Kidney rupture 21.06 9.55 13 427246 252 110161788
Central nervous system lesion 21.06 9.55 117 427142 15436 110146604
Cytomegalovirus gastritis 21.03 9.55 19 427240 669 110161371
Mouth ulceration 20.96 9.55 281 426978 47857 110114183
Thyroxine free increased 20.96 9.55 27 427232 1430 110160610
Troponin increased 20.95 9.55 53 427206 29713 110132327
Hospice care 20.94 9.55 11 427248 12462 110149578
Haematemesis 20.86 9.55 138 427121 58970 110103070
Fracture 20.85 9.55 40 427219 24748 110137292
Aeromonas infection 20.83 9.55 17 427242 520 110161520
Quadriparesis 20.82 9.55 52 427207 4655 110157385
Complications of transplanted lung 20.82 9.55 19 427240 678 110161362
Psoriasis 20.81 9.55 398 426861 139595 110022445
Tuberculosis gastrointestinal 20.80 9.55 18 427241 598 110161442
Herpes simplex colitis 20.79 9.55 10 427249 115 110161925
Fear 20.78 9.55 36 427223 23157 110138883
Product preparation error 20.76 9.55 8 427251 10871 110151169
Granulomatous liver disease 20.70 9.55 28 427231 1556 110160484
Episcleritis 20.68 9.55 25 427234 1241 110160799
Erosive duodenitis 20.61 9.55 34 427225 2257 110159783
Cytomegalovirus nephritis 20.60 9.55 11 427248 160 110161880
Meningoencephalitis bacterial 20.57 9.55 16 427243 456 110161584
Appendicitis 20.57 9.55 50 427209 28414 110133626
Back pain 20.54 9.55 1198 426061 369798 109792242
Human herpesvirus 6 encephalitis 20.54 9.55 23 427236 1051 110160989
Birdshot chorioretinopathy 20.54 9.55 9 427250 82 110161958
Sexual dysfunction 20.52 9.55 4 427255 8526 110153514
CSF protein increased 20.47 9.55 27 427232 1464 110160576
Disseminated toxoplasmosis 20.42 9.55 16 427243 461 110161579
Irritability 20.41 9.55 105 427154 47704 110114336
Pain in jaw 20.41 9.55 115 427144 51062 110110978
Erectile dysfunction 20.36 9.55 25 427234 18531 110143509
Acute myocardial infarction 20.32 9.55 216 427043 83561 110078479
Hemiparesis 20.26 9.55 259 427000 43644 110118396
Osteoporosis 20.25 9.55 460 426799 86692 110075348
Urine oxalate increased 20.22 9.55 12 427247 216 110161824
Bronchopulmonary aspergillosis allergic 20.17 9.55 4 427255 8422 110153618
Blood calcium increased 20.11 9.55 24 427235 18016 110144024
T-cell type acute leukaemia 20.08 9.55 14 427245 336 110161704
Myocarditis infectious 20.06 9.55 10 427249 125 110161915
Diaphragmatic injury 19.99 9.55 10 427249 126 110161914
Poikiloderma 19.99 9.55 16 427243 476 110161564
Ultrasound ovary abnormal 19.98 9.55 9 427250 88 110161952
Faciobrachial dystonic seizure 19.98 9.55 9 427250 88 110161952
Small intestinal obstruction 19.96 9.55 61 427198 32152 110129888
Urobilinogen urine increased 19.94 9.55 18 427241 633 110161407
Hypertensive encephalopathy 19.92 9.55 24 427235 1187 110160853
Syringe issue 19.92 9.55 6 427253 9519 110152521
Hemianopia 19.91 9.55 38 427221 2830 110159210
Unmasking of previously unidentified disease 19.91 9.55 38 427221 2830 110159210
Hypertransaminasaemia 19.85 9.55 161 427098 24094 110137946
Peptostreptococcus infection 19.84 9.55 11 427248 173 110161867
Ventricular fibrillation 19.82 9.55 87 427172 41226 110120814
Rhinitis allergic 19.82 9.55 24 427235 17898 110144142
Wound infection bacterial 19.81 9.55 22 427237 996 110161044
Chronic graft versus host disease in skin 19.81 9.55 36 427223 2583 110159457
Neoplasm progression 19.81 9.55 157 427102 64438 110097602
Familial periodic paralysis 19.75 9.55 14 427245 345 110161695
Endocarditis 19.74 9.55 103 427156 13268 110148772
Toxic neuropathy 19.70 9.55 23 427236 1100 110160940
Abscess 19.67 9.55 177 427082 27292 110134748
Anti-thyroid antibody positive 19.66 9.55 17 427242 564 110161476
Bordetella infection 19.65 9.55 12 427247 228 110161812
Acute oesophageal mucosal lesion 19.62 9.55 11 427248 177 110161863
Lymphoid tissue hypoplasia 19.62 9.55 28 427231 1637 110160403
Human herpesvirus 6 infection reactivation 19.60 9.55 23 427236 1106 110160934
Papilloma viral infection 19.60 9.55 32 427227 2106 110159934
Bacterial vulvovaginitis 19.54 9.55 18 427241 650 110161390
Headache 19.54 9.55 3052 424207 879325 109282715
Breast cancer female 19.49 9.55 12 427247 12456 110149584
Gastropleural fistula 19.48 9.55 8 427251 61 110161979
Dry throat 19.46 9.55 79 427180 9159 110152881
Complications of transplanted liver 19.43 9.55 16 427243 496 110161544
Peripheral artery aneurysm 19.34 9.55 16 427243 499 110161541
Chronic lymphocytic leukaemia recurrent 19.27 9.55 22 427237 1027 110161013
Genital herpes 19.25 9.55 35 427224 2512 110159528
Cutaneous lupus erythematosus 19.22 9.55 42 427217 3446 110158594
Angiocentric lymphoma 19.20 9.55 24 427235 1233 110160807
Engraftment syndrome 19.20 9.55 30 427229 1902 110160138
Cardiac arrest 19.19 9.55 596 426663 196157 109965883
Parainfluenzae virus infection 19.19 9.55 65 427194 6909 110155131
Suspected COVID-19 19.18 9.55 42 427217 3451 110158589
Dissociation 19.18 9.55 7 427252 9835 110152205
Cryptococcal cutaneous infection 19.16 9.55 13 427246 298 110161742
Peliosis hepatis 19.14 9.55 11 427248 186 110161854
B-lymphocyte count increased 19.12 9.55 10 427249 139 110161901
Lymphocytosis 19.11 9.55 55 427204 5356 110156684
Natural killer-cell leukaemia 19.06 9.55 9 427250 99 110161941
Gastrointestinal viral infection 19.06 9.55 28 427231 1681 110160359
Inflammatory marker increased 19.03 9.55 108 427151 14361 110147679
Subcapsular renal haematoma 19.01 9.55 21 427238 945 110161095
Small intestinal perforation 19.00 9.55 48 427211 4328 110157712
Hydrocephalus 18.98 9.55 85 427174 10290 110151750
Lichen sclerosus 18.97 9.55 23 427236 1145 110160895
Cytokine storm 18.96 9.55 26 427233 1464 110160576
Miosis 18.91 9.55 35 427224 21948 110140092
Nasal polyps 18.90 9.55 14 427245 13186 110148854
Tracheobronchitis 18.87 9.55 36 427223 2680 110159360
Porphyria acute 18.87 9.55 27 427232 18753 110143287
Arterial intramural haematoma 18.86 9.55 12 427247 246 110161794
Joint range of motion decreased 18.85 9.55 344 426915 121488 110040552
Agitation 18.84 9.55 315 426944 112736 110049304
Blood sodium decreased 18.81 9.55 80 427179 38239 110123801
Platelet count decreased 18.78 9.55 714 426545 229729 109932311
Glomerulonephritis rapidly progressive 18.76 9.55 32 427227 2183 110159857
Sinus polyp degeneration 18.73 9.55 8 427251 68 110161972
Pyrexia 18.67 9.55 3835 423424 894430 109267610
Epistaxis 18.67 9.55 373 426886 129999 110032041
Aspergilloma 18.62 9.55 19 427240 780 110161260
Depression 18.60 9.55 1019 426240 316316 109845724
Surgery 18.58 9.55 89 427170 41194 110120846
Trichosporon infection 18.56 9.55 24 427235 1276 110160764
Seizure 18.54 9.55 683 426576 220502 109941538
Neutropenic sepsis 18.50 9.55 59 427200 30687 110131353
ADAMTS13 activity decreased 18.50 9.55 13 427246 316 110161724
Gastritis fungal 18.46 9.55 13 427246 317 110161723
Post procedural urine leak 18.45 9.55 10 427249 150 110161890
Cerebral venous sinus thrombosis 18.45 9.55 37 427222 2858 110159182
Renal artery stenosis 18.45 9.55 43 427216 3683 110158357
Hypoaesthesia 18.42 9.55 1009 426250 313214 109848826
Glomerulonephritis membranous 18.39 9.55 30 427229 1973 110160067
Hypomagnesaemia 18.39 9.55 147 427112 60223 110101817
Clostridium colitis 18.36 9.55 40 427219 3275 110158765
Uraemic encephalopathy 18.36 9.55 19 427240 793 110161247
Necrosis 18.34 9.55 90 427169 11316 110150724
Carotid artery occlusion 18.31 9.55 7 427252 9558 110152482
Haemoperitoneum 18.29 9.55 54 427205 5334 110156706
Thirst 18.28 9.55 35 427224 21672 110140368
Temperature intolerance 18.26 9.55 104 427155 13846 110148194
Amoebiasis 18.22 9.55 10 427249 154 110161886
Metabolic encephalopathy 18.21 9.55 10 427249 11050 110150990
Listeria encephalitis 18.18 9.55 13 427246 325 110161715
Venous thrombosis 18.13 9.55 73 427186 8432 110153608
Sopor 18.13 9.55 76 427183 36470 110125570
Haemophilus infection 18.10 9.55 36 427223 2764 110159276
Mycobacterium kansasii infection 18.09 9.55 14 427245 396 110161644
Cytopenia 18.09 9.55 187 427072 29929 110132111
Product administration error 18.09 9.55 78 427181 37139 110124901
Urethral polyp 18.06 9.55 8 427251 75 110161965
Haemorrhagic varicella syndrome 18.05 9.55 5 427254 8 110162032
Tumefactive multiple sclerosis 18.05 9.55 10 427249 157 110161883
Atrial flutter 18.02 9.55 42 427217 24220 110137820
Chest discomfort 18.02 9.55 833 426426 173015 109989025
Dysstasia 18.02 9.55 66 427193 32920 110129120
Marrow hyperplasia 18.00 9.55 28 427231 1768 110160272
Serratia sepsis 18.00 9.55 12 427247 267 110161773
Shock 17.94 9.55 299 426960 53289 110108751
Muscular weakness 17.91 9.55 1151 426108 247317 109914723
Hilar lymphadenopathy 17.87 9.55 32 427227 2270 110159770
Monocyte percentage increased 17.86 9.55 32 427227 2271 110159769
Injection site rash 17.83 9.55 40 427219 23379 110138661
Vitamin B12 increased 17.82 9.55 30 427229 2025 110160015
Encephalomyelitis 17.81 9.55 13 427246 336 110161704
Blood pressure decreased 17.79 9.55 325 426934 114766 110047274
Thunderclap headache 17.74 9.55 16 427243 562 110161478
Injection site induration 17.74 9.55 11 427248 11372 110150668
Electrocardiogram abnormal 17.73 9.55 28 427231 18681 110143359
Coronary artery aneurysm 17.72 9.55 10 427249 163 110161877
Fungal abscess central nervous system 17.70 9.55 11 427248 216 110161824
Cough 17.69 9.55 2040 425219 459601 109702439
Right ventricular failure 17.66 9.55 47 427212 25907 110136133
Carotid artery thrombosis 17.66 9.55 79 427180 9559 110152481
Depressed mood 17.64 9.55 150 427109 60659 110101381
Glomerulonephritis membranoproliferative 17.64 9.55 19 427240 831 110161209
Muscle rigidity 17.53 9.55 42 427217 23989 110138051
Cutaneous malacoplakia 17.51 9.55 10 427249 167 110161873
Delayed engraftment 17.50 9.55 12 427247 280 110161760
Encephalitis viral 17.48 9.55 37 427222 2970 110159070
Mycobacterium marinum infection 17.48 9.55 18 427241 747 110161293
Blood pressure systolic decreased 17.46 9.55 100 427159 13341 110148699
Cystitis 17.42 9.55 355 426904 65681 110096359
Aspiration 17.41 9.55 60 427199 30473 110131567
Blood lactate dehydrogenase increased 17.37 9.55 254 427005 44080 110117960
Erythema infectiosum 17.31 9.55 11 427248 225 110161815
Oral pain 17.28 9.55 80 427179 37364 110124676
Interleukin level increased 17.27 9.55 26 427233 1595 110160445
Paraplegia 17.25 9.55 58 427201 6142 110155898
Fungal sepsis 17.24 9.55 31 427228 2206 110159834
Tracheobronchitis viral 17.24 9.55 6 427253 27 110162013
Complication associated with device 17.23 9.55 32 427227 20041 110141999
Meningomyelitis herpes 17.18 9.55 8 427251 85 110161955
Meningitis 17.18 9.55 90 427169 11612 110150428
Second primary malignancy 17.16 9.55 27 427232 18041 110143999
Vaccination failure 17.15 9.55 33 427226 2473 110159567
Foetal growth restriction 17.12 9.55 37 427222 3013 110159027
Bradypnoea 17.11 9.55 6 427253 8643 110153397
Coccidioidomycosis 17.08 9.55 26 427233 1611 110160429
Coagulopathy 17.07 9.55 237 427022 40674 110121366
Infusion site reaction 17.07 9.55 122 427137 17560 110144480
Hyperferritinaemia 17.06 9.55 21 427238 1062 110160978
Moyamoya disease 17.03 9.55 9 427250 128 110161912
Butterfly rash 17.03 9.55 30 427229 2101 110159939
Osteogenesis imperfecta 17.01 9.55 18 427241 771 110161269
Intestinal intraepithelial lymphocytes increased 17.01 9.55 11 427248 232 110161808
Withdrawal syndrome 17 9.55 63 427196 31317 110130723
Q fever 16.96 9.55 12 427247 295 110161745
Myelitis 16.93 9.55 38 427221 3175 110158865
Specific gravity urine increased 16.92 9.55 15 427244 515 110161525
Demodicidosis 16.89 9.55 11 427248 235 110161805
Neurologic neglect syndrome 16.88 9.55 76 427183 9222 110152818
Multisystem inflammatory syndrome in children 16.86 9.55 7 427252 55 110161985
Blood potassium decreased 16.84 9.55 131 427128 53983 110108057
Hypertrichosis 16.83 9.55 27 427232 1751 110160289
Extremity necrosis 16.81 9.55 42 427217 3760 110158280
Arterial rupture 16.81 9.55 19 427240 877 110161163
Granuloma 16.80 9.55 77 427182 9413 110152627
Vaginal discharge 16.78 9.55 27 427232 17881 110144159
Fibrin D dimer increased 16.78 9.55 79 427180 9766 110152274
Thrombotic thrombocytopenic purpura 16.76 9.55 63 427196 7048 110154992
Septic arthritis staphylococcal 16.73 9.55 19 427240 882 110161158
Autoimmune haemolytic anaemia 16.72 9.55 83 427176 10484 110151556
Lupus myocarditis 16.71 9.55 8 427251 91 110161949
Eye infection fungal 16.67 9.55 16 427243 609 110161431
Muir-Torre syndrome 16.65 9.55 7 427252 57 110161983
Angiosarcoma metastatic 16.61 9.55 10 427249 185 110161855
Device related sepsis 16.60 9.55 66 427193 7581 110154459
Japanese spotted fever 16.57 9.55 6 427253 31 110162009
Cytomegalovirus gastrointestinal ulcer 16.55 9.55 9 427250 136 110161904
Terminal ileitis 16.53 9.55 26 427233 1658 110160382
Drug tolerance 16.51 9.55 24 427235 16561 110145479
Accident 16.50 9.55 11 427248 10941 110151099
Acinetobacter sepsis 16.49 9.55 9 427250 137 110161903
Chimerism 16.48 9.55 12 427247 309 110161731
Gastrointestinal pain 16.45 9.55 13 427246 11847 110150193
Tendonitis 16.44 9.55 49 427210 26034 110136006
Urine bilirubin decreased 16.44 9.55 9 427250 138 110161902
Cryptitis 16.43 9.55 13 427246 380 110161660
Intestinal ischaemia 16.42 9.55 113 427146 16066 110145974
Hemiplegia 16.42 9.55 147 427112 22635 110139405
Thyroid gland abscess 16.41 9.55 8 427251 95 110161945
Eye pruritus 16.35 9.55 68 427191 32707 110129333
Hallucination, auditory 16.35 9.55 50 427209 26347 110135693
Myelopathy 16.26 9.55 53 427206 5523 110156517
Cancer in remission 16.24 9.55 7 427252 61 110161979
Atrioventricular block 16.24 9.55 25 427234 16852 110145188
Cystitis viral 16.23 9.55 24 427235 1449 110160591
Bronchopneumopathy 16.19 9.55 19 427240 914 110161126
Drug eruption 16.19 9.55 131 427128 53528 110108512
Cystitis bacterial 16.15 9.55 22 427237 1231 110160809
Histology abnormal 16.15 9.55 13 427246 390 110161650
Band neutrophil percentage increased 16.12 9.55 13 427246 391 110161649
Diffuse large B-cell lymphoma stage III 16.12 9.55 8 427251 99 110161941
Encephalitis fungal 16.10 9.55 11 427248 255 110161785
Reticulocytopenia 16.08 9.55 12 427247 321 110161719
Blood creatinine decreased 16.08 9.55 74 427185 9063 110152977
Trichophytosis 16.05 9.55 14 427245 470 110161570
Complication of device insertion 16.05 9.55 7 427252 8831 110153209
Orbital apex syndrome 16.05 9.55 8 427251 100 110161940
Hypokinesia 16.04 9.55 38 427221 21788 110140252
Salmonellosis 16.04 9.55 30 427229 2201 110159839
Anuria 16.00 9.55 154 427105 24187 110137853
Gonococcal infection 15.95 9.55 7 427252 64 110161976
Cytomegalovirus duodenitis 15.94 9.55 9 427250 147 110161893
Oropharyngeal plaque 15.93 9.55 14 427245 475 110161565
Actinomycotic sepsis 15.93 9.55 10 427249 200 110161840
Blood creatine phosphokinase increased 15.93 9.55 193 427066 72884 110089156
Menstruation irregular 15.92 9.55 54 427205 5743 110156297
Walking aid user 15.89 9.55 47 427212 25028 110137012
Linear IgA disease 15.88 9.55 45 427214 4344 110157696
Exposure during pregnancy 15.83 9.55 795 426464 166629 109995411
Hereditary angioedema 15.78 9.55 4 427255 7110 110154930
Body temperature increased 15.73 9.55 298 426961 54415 110107625
Hyperplasia 15.68 9.55 24 427235 1494 110160546
Substance abuse 15.66 9.55 15 427244 12448 110149592
Multi-organ disorder 15.64 9.55 38 427221 3343 110158697
Mediastinitis 15.60 9.55 23 427236 1385 110160655
Subdural haematoma 15.60 9.55 80 427179 36374 110125666
Norovirus test positive 15.59 9.55 19 427240 951 110161089
Astrovirus test positive 15.55 9.55 6 427253 38 110162002
Torulopsis infection 15.55 9.55 6 427253 38 110162002
Renal hypertrophy 15.55 9.55 6 427253 38 110162002
Gastrointestinal disorder 15.49 9.55 770 426489 241182 109920858
Smooth muscle cell neoplasm 15.49 9.55 23 427236 1394 110160646
Meningitis exserohilum 15.48 9.55 4 427255 4 110162036
Nephropathy 15.45 9.55 97 427162 13370 110148670
Jejunal perforation 15.43 9.55 13 427246 416 110161624
Blood magnesium decreased 15.35 9.55 34 427225 19962 110142078
Forced expiratory volume decreased 15.26 9.55 17 427242 13159 110148881
Hepatitis toxic 15.26 9.55 54 427205 5867 110156173
Cerebellar stroke 15.20 9.55 18 427241 874 110161166
Transient hypogammaglobulinaemia of infancy 15.17 9.55 6 427253 41 110161999
Joint tuberculosis 15.14 9.55 10 427249 219 110161821
Tinnitus 15.13 9.55 155 427104 60385 110101655
Normal newborn 15.13 9.55 140 427119 21756 110140284
Leukoencephalopathy 15.10 9.55 73 427186 9122 110152918
Device occlusion 15.09 9.55 22 427237 15163 110146877
Arterial spasm 15.07 9.55 9 427250 164 110161876
Eosinopenia 15.06 9.55 8 427251 115 110161925
Disseminated trichosporonosis 15.06 9.55 10 427249 221 110161819
Creatinine urine increased 15.05 9.55 14 427245 512 110161528
Malignant catatonia 15.03 9.55 16 427243 690 110161350
Peritoneal candidiasis 15.03 9.55 5 427254 19 110162021
Actinomycosis 15.01 9.55 22 427237 1318 110160722
Muscle twitching 15.00 9.55 62 427197 29873 110132167
Subacute sclerosing panencephalitis 14.99 9.55 7 427252 75 110161965
Blood phosphorus increased 14.97 9.55 25 427234 16315 110145725
JC polyomavirus test positive 14.96 9.55 30 427229 2317 110159723
Pharyngeal disorder 14.95 9.55 33 427226 2726 110159314
Adenoviral hepatitis 14.95 9.55 19 427240 993 110161047
Mucocutaneous leishmaniasis 14.94 9.55 14 427245 517 110161523
Viral cardiomyopathy 14.93 9.55 6 427253 43 110161997
Clonal haematopoiesis 14.93 9.55 9 427250 167 110161873
Band neutrophil count increased 14.87 9.55 16 427243 699 110161341
Duodenal perforation 14.86 9.55 33 427226 2737 110159303
Administration site bruise 14.86 9.55 10 427249 226 110161814
Immune effector cell-associated neurotoxicity syndrome 14.86 9.55 103 427156 14679 110147361
Breast cancer stage I 14.83 9.55 5 427254 7382 110154658
Haematuria traumatic 14.82 9.55 12 427247 363 110161677
Thyroid stimulating immunoglobulin increased 14.79 9.55 9 427250 170 110161870
Asphyxia 14.72 9.55 20 427239 14195 110147845
Myelosuppression 14.71 9.55 266 426993 94074 110067966
Retinal detachment 14.69 9.55 83 427176 11017 110151023
Catheterisation cardiac 14.69 9.55 3 427256 6188 110155852
Pulmonary air leakage 14.69 9.55 11 427248 296 110161744
Arteriovenous fistula 14.67 9.55 23 427236 1462 110160578
Secondary adrenocortical insufficiency 14.64 9.55 44 427215 4390 110157650
Listeria sepsis 14.63 9.55 17 427242 809 110161231
Cervical plexus lesion 14.60 9.55 4 427255 6 110162034
Hypothyroidism 14.60 9.55 196 427063 72703 110089337
Herpes simplex meningoencephalitis 14.59 9.55 7 427252 80 110161960
Ovarian fibroma 14.59 9.55 7 427252 80 110161960
Product use issue 14.58 9.55 1022 426237 310673 109851367
Gastroenteritis salmonella 14.58 9.55 22 427237 1353 110160687
Red blood cell count increased 14.57 9.55 47 427212 4871 110157169
Heliotrope rash 14.56 9.55 10 427249 234 110161806
Parathyroid hyperplasia 14.56 9.55 9 427250 175 110161865
Histoplasmosis 14.54 9.55 34 427225 2919 110159121
Bundle branch block left 14.53 9.55 17 427242 12871 110149169
Marginal zone lymphoma 14.52 9.55 10 427249 235 110161805
Radiotherapy to brain 14.47 9.55 6 427253 47 110161993
Weight decreased 14.45 9.55 1585 425674 466472 109695568
Epiglottic erythema 14.44 9.55 7 427252 82 110161958
Monocyte count decreased 14.44 9.55 40 427219 3811 110158229
Tick-borne viral encephalitis 14.42 9.55 9 427250 178 110161862
Chemotherapeutic drug level above therapeutic 14.42 9.55 8 427251 126 110161914
Oropharyngeal pain 14.41 9.55 650 426609 134626 110027414
Lactic acidosis 14.37 9.55 262 426997 92549 110069491
Optic perineuritis 14.36 9.55 6 427253 48 110161992
Complications of transplanted heart 14.36 9.55 13 427246 459 110161581
Maternal exposure timing unspecified 14.34 9.55 38 427221 20975 110141065
Cardiac murmur 14.31 9.55 48 427211 24580 110137460
Biloma 14.27 9.55 10 427249 242 110161798
Device failure 14.26 9.55 5 427254 7202 110154838
Meningitis bacterial 14.22 9.55 35 427224 3104 110158936
Coronary artery bypass 14.19 9.55 3 427256 6039 110156001
Leukocyturia 14.19 9.55 29 427230 2271 110159769
Disorientation 14.15 9.55 190 427069 70481 110091559
Seroconversion test positive 14.15 9.55 6 427253 50 110161990
Panniculitis 14.13 9.55 24 427235 15558 110146482
Product complaint 14.12 9.55 20 427239 13952 110148088
Dehiscence 14.10 9.55 16 427243 742 110161298
Cutaneous B-cell lymphoma 14.09 9.55 8 427251 132 110161908
Splenic necrosis 14.08 9.55 9 427250 186 110161854
Myocardiac abscess 14.08 9.55 7 427252 87 110161953
Propofol infusion syndrome 14.07 9.55 31 427228 2558 110159482
Eye infection toxoplasmal 14.06 9.55 16 427243 744 110161296
Ketoacidosis 14.06 9.55 11 427248 10076 110151964
Dust allergy 14.05 9.55 3 427256 5998 110156042
Central nervous system abscess 14.05 9.55 6 427253 51 110161989
Mesenteric haemorrhage 14.01 9.55 7 427252 88 110161952
Nephrolithiasis 14.00 9.55 176 427083 66036 110096004
Pneumonitis 13.95 9.55 391 426868 76140 110085900
Benign mediastinal neoplasm 13.95 9.55 6 427253 52 110161988
Migraine 13.94 9.55 532 426727 171120 109990920
Community acquired infection 13.94 9.55 5 427254 25 110162015
Pyometra 13.94 9.55 7 427252 89 110161951
Injection site discolouration 13.90 9.55 9 427250 9094 110152946
Lung infiltration 13.89 9.55 151 427108 24477 110137563
Gastroenteritis Escherichia coli 13.86 9.55 21 427238 1296 110160744
Myasthenia gravis crisis 13.80 9.55 25 427234 1789 110160251
Ulcer haemorrhage 13.80 9.55 43 427216 22528 110139512
Drug dependence 13.80 9.55 125 427134 49895 110112145
Aortitis salmonella 13.78 9.55 5 427254 26 110162014
Bone loss 13.78 9.55 34 427225 3021 110159019
Coronary arterial stent insertion 13.76 9.55 3 427256 5912 110156128
Sinus congestion 13.76 9.55 179 427080 30280 110131760
Amoebic dysentery 13.75 9.55 6 427253 54 110161986
Pneumonia influenzal 13.75 9.55 39 427220 3766 110158274
Extra dose administered 13.74 9.55 16 427243 12143 110149897
Gastrointestinal fungal infection 13.74 9.55 16 427243 763 110161277
Hepatic infection fungal 13.72 9.55 11 427248 328 110161712
Dizziness postural 13.72 9.55 22 427237 14587 110147453
Pneumonia lipoid 13.71 9.55 9 427250 195 110161845
Lymphangitis 13.70 9.55 23 427236 1549 110160491
Haemorrhagic stroke 13.68 9.55 20 427239 13769 110148271
Natural killer cell activity decreased 13.68 9.55 3 427256 0 110162040
Reticuloendothelial dysfunction 13.68 9.55 3 427256 0 110162040
Treatment noncompliance 13.64 9.55 199 427060 72791 110089249
Infected varicose vein 13.62 9.55 5 427254 27 110162013
Vasculitis necrotising 13.58 9.55 23 427236 1560 110160480
Splenic abscess 13.56 9.55 18 427241 982 110161058
Blood loss anaemia 13.55 9.55 31 427228 17994 110144046
Pneumatosis 13.55 9.55 18 427241 983 110161057
Acinetobacter bacteraemia 13.52 9.55 11 427248 335 110161705
Diabetic macroangiopathy 13.48 9.55 8 427251 144 110161896
Lower respiratory tract congestion 13.46 9.55 45 427214 4751 110157289
Haemolysis 13.45 9.55 105 427154 15534 110146506
Multiple fractures 13.44 9.55 9 427250 8931 110153109
Paranoia 13.42 9.55 43 427216 22331 110139709
Pancreatic carcinoma 13.40 9.55 23 427236 14849 110147191
Hyperammonaemia 13.40 9.55 95 427164 13637 110148403
Enterobacter pneumonia 13.40 9.55 14 427245 591 110161449
Renal cyst infection 13.39 9.55 10 427249 268 110161772
Chronic hepatitis C 13.38 9.55 15 427244 686 110161354
Premenstrual syndrome 13.38 9.55 14 427245 592 110161448
Blood gases abnormal 13.37 9.55 21 427238 1337 110160703
Metastatic malignant melanoma 13.37 9.55 36 427223 3373 110158667
Eschar 13.35 9.55 22 427237 1459 110160581
Ureteral necrosis 13.34 9.55 7 427252 98 110161942
Herpes ophthalmic 13.34 9.55 25 427234 1837 110160203
Brain oedema 13.32 9.55 181 427078 30917 110131123
Acute allograft nephropathy 13.29 9.55 6 427253 59 110161981
Haemangioma-thrombocytopenia syndrome 13.27 9.55 4 427255 10 110162030
SJS-TEN overlap 13.22 9.55 25 427234 1849 110160191
Oculomotor study abnormal 13.19 9.55 5 427254 30 110162010
Vaginal haemorrhage 13.16 9.55 51 427208 25023 110137017
Cardiac pacemaker insertion 13.12 9.55 4 427255 6297 110155743
Mediastinal cyst 13.12 9.55 6 427253 61 110161979
Renal and pancreas transplant rejection 13.12 9.55 6 427253 61 110161979
Allergy test positive 13.12 9.55 17 427242 906 110161134
Exposure via skin contact 13.11 9.55 19 427240 13128 110148912
Lymphoproliferative disorder 13.10 9.55 59 427200 7159 110154881
Oral bacterial infection 13.10 9.55 7 427252 102 110161938
Hypertriglyceridaemia 13.10 9.55 107 427152 16047 110145993
Pleural mass 13.10 9.55 7 427252 102 110161938
Fracture pain 13.08 9.55 19 427240 1129 110160911
Tubulointerstitial nephritis 13.08 9.55 288 426971 53996 110108044
Acne fulminans 13.07 9.55 10 427249 278 110161762
Rotavirus infection 13.06 9.55 17 427242 910 110161130
Blood urea increased 13.06 9.55 291 426968 54666 110107374
Type IIb hyperlipidaemia 13.05 9.55 5 427254 31 110162009
Lymphocytic infiltration 13.05 9.55 26 427233 1999 110160041
Night sweats 13.03 9.55 406 426853 133577 110028463
Ear pain 13.00 9.55 137 427122 53089 110108951
Respiratory tract inflammation 12.97 9.55 18 427241 1025 110161015
Porokeratosis 12.92 9.55 10 427249 283 110161757
Acinetobacter test positive 12.92 9.55 10 427249 283 110161757
SARS-CoV-2 RNA 12.92 9.55 5 427254 32 110162008
Ureteric anastomosis complication 12.92 9.55 5 427254 32 110162008
Sense of oppression 12.91 9.55 23 427236 1625 110160415
Cryoglobulinaemia 12.90 9.55 20 427239 1259 110160781
Tricuspid valve incompetence 12.89 9.55 48 427211 23825 110138215
Bladder cancer 12.88 9.55 38 427221 20254 110141786
Aspergillus test positive 12.88 9.55 18 427241 1032 110161008
Gastrointestinal perforation 12.83 9.55 60 427199 7396 110154644
Gastroenteritis sapovirus 12.80 9.55 9 427250 219 110161821
Tension headache 12.77 9.55 11 427248 9607 110152433
Arthralgia 12.76 9.55 2740 424519 776892 109385148
Pulmonary cavitation 12.76 9.55 27 427232 2167 110159873
Colitis ulcerative 12.74 9.55 216 427043 77147 110084893
Obsessive-compulsive disorder 12.74 9.55 6 427253 7235 110154805
Dyschromatopsia 12.73 9.55 20 427239 1274 110160766
Burns second degree 12.72 9.55 7 427252 7726 110154314
Tri-iodothyronine free decreased 12.72 9.55 12 427247 447 110161593
Pelvic venous thrombosis 12.72 9.55 31 427228 2733 110159307
Meningitis listeria 12.69 9.55 20 427239 1277 110160763
Dry mouth 12.67 9.55 637 426622 199311 109962729
Endocarditis bacterial 12.64 9.55 24 427235 1781 110160259
Perineal ulceration 12.63 9.55 7 427252 110 110161930
Double stranded DNA antibody positive 12.63 9.55 13 427246 539 110161501
Cryptococcal fungaemia 12.56 9.55 10 427249 295 110161745
Spinal disorder 12.55 9.55 83 427176 11645 110150395
Viral vasculitis 12.55 9.55 9 427250 226 110161814
Encephalitis Japanese B 12.55 9.55 6 427253 68 110161972
Breath sounds abnormal 12.49 9.55 53 427206 25351 110136689
Hypofibrinogenaemia 12.49 9.55 29 427230 2478 110159562
Myelocyte percentage increased 12.48 9.55 9 427250 228 110161812
Keratitis 12.48 9.55 46 427213 5098 110156942
Cestode infection 12.48 9.55 10 427249 298 110161742
Blood glucose decreased 12.45 9.55 65 427194 29423 110132617
Hairy cell leukaemia 12.44 9.55 8 427251 167 110161873
Tumour flare 12.44 9.55 22 427237 1545 110160495
Haemoglobin abnormal 12.42 9.55 10 427249 9028 110153012
Peripheral vascular disorder 12.40 9.55 9 427250 8567 110153473
Abdominal wall abscess 12.39 9.55 22 427237 1550 110160490
Application site pain 12.37 9.55 3 427256 5496 110156544
Prescription drug used without a prescription 12.36 9.55 3 427256 5493 110156547
Haemorrhoidal haemorrhage 12.36 9.55 8 427251 8085 110153955
Rheumatoid factor 12.32 9.55 13 427246 555 110161485
Adrenal atrophy 12.32 9.55 6 427253 71 110161969
White coat hypertension 12.31 9.55 20 427239 1311 110160729
Retinal scar 12.28 9.55 12 427247 467 110161573
Cardiogenic shock 12.28 9.55 152 427107 57186 110104854
Lumbosacral plexus lesion 12.28 9.55 4 427255 14 110162026
X-ray limb abnormal 12.28 9.55 4 427255 14 110162026
Interferon gamma release assay positive 12.28 9.55 8 427251 171 110161869
Crying 12.28 9.55 54 427205 25574 110136466
Fluid retention 12.27 9.55 274 426985 94033 110068007
Excessive skin 12.25 9.55 7 427252 117 110161923
Arteritis coronary 12.25 9.55 6 427253 72 110161968
Mean cell haemoglobin concentration increased 12.25 9.55 18 427241 1081 110160959
Brain herniation 12.22 9.55 67 427192 8796 110153244
Hepatic steatosis 12.21 9.55 125 427134 48706 110113334
Cutaneous nocardiosis 12.20 9.55 10 427249 308 110161732
Mycobacterium avium complex infection 12.18 9.55 50 427209 5827 110156213
Meningioma malignant 12.18 9.55 6 427253 73 110161967
Transaminases increased 12.16 9.55 326 426933 63064 110098976
Biliary anastomosis complication 12.16 9.55 8 427251 174 110161866
Nocturia 12.15 9.55 30 427229 16960 110145080
Cardiovascular disorder 12.13 9.55 46 427213 22714 110139326
Exophthalmos 12.11 9.55 27 427232 2246 110159794
Dermatophytosis 12.10 9.55 13 427246 567 110161473
Ear swelling 12.09 9.55 26 427233 2110 110159930
Eye luxation 12.07 9.55 4 427255 15 110162025
Infertility 12.06 9.55 15 427244 767 110161273
Candida test positive 12.04 9.55 20 427239 1335 110160705
Groin pain 12.04 9.55 26 427233 15402 110146638
Liver injury 12.04 9.55 467 426792 149946 110012094
Drug level decreased 12.02 9.55 117 427142 18431 110143609
Intestinal ulcer 12.01 9.55 28 427231 2399 110159641
Haptoglobin decreased 12.00 9.55 23 427236 1718 110160322
Pseudoaldosteronism 11.98 9.55 10 427249 316 110161724
Vein disorder 11.95 9.55 52 427207 6218 110155822
Respiratory gas exchange disorder 11.93 9.55 16 427243 882 110161158
Inadequate aseptic technique in use of product 11.89 9.55 7 427252 124 110161916
Chronic graft versus host disease in intestine 11.89 9.55 14 427245 676 110161364
Carotid artery insufficiency 11.86 9.55 4 427255 16 110162024
Renal artery perforation 11.86 9.55 4 427255 16 110162024
Acute endocarditis 11.86 9.55 5 427254 41 110161999
Symptom recurrence 11.85 9.55 43 427216 4729 110157311
Endometrial disorder 11.85 9.55 14 427245 678 110161362
Arthritis bacterial 11.84 9.55 77 427182 10743 110151297
Body height decreased 11.83 9.55 14 427245 10549 110151491
Thrombosis in device 11.80 9.55 3 427256 5324 110156716
Conjunctivitis allergic 11.80 9.55 6 427253 6925 110155115
Latent tuberculosis 11.77 9.55 38 427221 3939 110158101
Glomerulonephritis proliferative 11.77 9.55 12 427247 492 110161548
Schistocytosis 11.76 9.55 6 427253 79 110161961
Clostridium difficile infection 11.75 9.55 274 426985 51855 110110185
Focal nodular hyperplasia 11.72 9.55 16 427243 897 110161143
Wrong technique in device usage process 11.71 9.55 6 427253 6895 110155145
Priapism 11.71 9.55 4 427255 5857 110156183
Metastases to bone 11.71 9.55 72 427187 31300 110130740
Cellulitis orbital 11.67 9.55 17 427242 1013 110161027
Upper airway necrosis 11.66 9.55 5 427254 43 110161997
Bone abscess 11.63 9.55 14 427245 692 110161348
Haemorrhagic pneumonia 11.62 9.55 8 427251 188 110161852
Ageusia 11.61 9.55 38 427221 19607 110142433
Pericarditis constrictive 11.60 9.55 17 427242 1018 110161022
Urinoma 11.59 9.55 9 427250 256 110161784
Atrial tachycardia 11.58 9.55 11 427248 9167 110152873
Sensitivity to weather change 11.55 9.55 13 427246 10015 110152025
SARS-CoV-2 RNA increased 11.54 9.55 8 427251 190 110161850
Arrhythmia 11.54 9.55 194 427065 69381 110092659
Uterine perforation 11.53 9.55 6 427253 6834 110155206
Oesophageal ulcer 11.52 9.55 61 427198 7903 110154137
Intra-abdominal haemorrhage 11.51 9.55 46 427213 5296 110156744
Chronic papillomatous dermatitis 11.50 9.55 6 427253 83 110161957
Polymyositis 11.50 9.55 36 427223 3672 110158368
Retinal degeneration 11.48 9.55 22 427237 1644 110160396
Abnormal behaviour 11.46 9.55 96 427163 38943 110123097
Periostitis 11.45 9.55 15 427244 808 110161232
Bacterial pyelonephritis 11.42 9.55 15 427244 810 110161230
Activated partial thromboplastin time prolonged 11.41 9.55 46 427213 22322 110139718
Sickle cell anaemia with crisis 11.41 9.55 12 427247 9533 110152507
Euglycaemic diabetic ketoacidosis 11.39 9.55 17 427242 11606 110150434
Cells in urine 11.36 9.55 8 427251 195 110161845
Activated partial thromboplastin time shortened 11.33 9.55 17 427242 1040 110161000
Infectious thyroiditis 11.33 9.55 8 427251 196 110161844
Sudden death 11.33 9.55 52 427207 24343 110137697
Ileal ulcer 11.32 9.55 23 427236 1794 110160246
Hepatic infection 11.31 9.55 19 427240 1280 110160760
Perforation bile duct 11.31 9.55 6 427253 86 110161954
Femoral nerve palsy 11.31 9.55 6 427253 86 110161954
Optic atrophy 11.31 9.55 28 427231 2493 110159547
Breast cancer metastatic 11.31 9.55 16 427243 11165 110150875
Foetal death 11.29 9.55 103 427156 15942 110146098
Mucosal ulceration 11.29 9.55 27 427232 2352 110159688
Conjunctival oedema 11.28 9.55 21 427238 1535 110160505
Hepatitis C RNA increased 11.26 9.55 11 427248 428 110161612
Sinus node dysfunction 11.24 9.55 11 427248 9036 110153004
Coombs direct test positive 11.21 9.55 12 427247 521 110161519
Microvillous inclusion disease 11.18 9.55 9 427250 270 110161770
Cerebral toxoplasmosis 11.16 9.55 32 427227 3110 110158930
Haematoma muscle 11.15 9.55 38 427221 4052 110157988
Arterial occlusive disease 11.15 9.55 99 427160 15209 110146831
Oral disorder 11.11 9.55 82 427177 11921 110150119
Refractory anaemia with an excess of blasts 11.11 9.55 15 427244 832 110161208
Arthritis fungal 11.09 9.55 8 427251 203 110161837
Presyncope 11.08 9.55 128 427131 48759 110113281
Infusion site extravasation 11.07 9.55 80 427179 11554 110150486
Eastern Cooperative Oncology Group performance status 11.06 9.55 7 427252 142 110161898
Autoimmune colitis 11.05 9.55 24 427235 1961 110160079
Retroperitoneal haematoma 11.04 9.55 50 427209 6081 110155959
Germ cell cancer 11.02 9.55 8 427251 205 110161835
Testicular cancer metastatic 11.01 9.55 6 427253 91 110161949
Hepatic encephalopathy 10.99 9.55 64 427195 28192 110133848
Arthritis 10.98 9.55 532 426727 167054 109994986
Metastases to central nervous system 10.98 9.55 48 427211 22769 110139271
Urinary casts 10.96 9.55 19 427240 1313 110160727
Glomerulonephropathy 10.95 9.55 10 427249 357 110161683
Hepatic haemorrhage 10.94 9.55 19 427240 1315 110160725
Transferrin decreased 10.94 9.55 12 427247 536 110161504
Vein rupture 10.92 9.55 28 427231 2547 110159493
Movement disorder 10.92 9.55 89 427170 36315 110125725
Escherichia bacteraemia 10.92 9.55 72 427187 10092 110151948
Application site erythema 10.92 9.55 4 427255 5606 110156434
Abscess fungal 10.91 9.55 11 427248 445 110161595
Developmental delay 10.91 9.55 20 427239 1445 110160595
Creatinine urine decreased 10.88 9.55 10 427249 360 110161680
Meningitis chemical 10.88 9.55 10 427249 360 110161680
Pneumonia aspiration 10.86 9.55 235 427024 80998 110081042
Vitello-intestinal duct remnant 10.85 9.55 7 427252 147 110161893
Hepatic cyst infection 10.85 9.55 8 427251 210 110161830
Spinal cord infarction 10.84 9.55 17 427242 1081 110160959
Castleman's disease 10.84 9.55 4 427255 22 110162018
Small intestine gangrene 10.83 9.55 5 427254 52 110161988
Fibrosarcoma 10.83 9.55 5 427254 52 110161988
Lower motor neurone lesion 10.83 9.55 5 427254 52 110161988
Paradoxical drug reaction 10.83 9.55 70 427189 9747 110152293
Accelerated idioventricular rhythm 10.82 9.55 9 427250 283 110161757
Delusion 10.82 9.55 51 427208 23704 110138336
Hyperoxaluria 10.81 9.55 10 427249 363 110161677
Breast cancer 10.77 9.55 96 427163 38446 110123594
Eye abscess 10.75 9.55 10 427249 366 110161674
Febrile infection-related epilepsy syndrome 10.73 9.55 6 427253 96 110161944
Throat clearing 10.73 9.55 39 427220 4294 110157746
Colitis ischaemic 10.72 9.55 34 427225 17716 110144324
Adjustment disorder 10.72 9.55 75 427184 10720 110151320
Extrapulmonary tuberculosis 10.70 9.55 12 427247 549 110161491
Back disorder 10.69 9.55 43 427216 20879 110141161
Post infection glomerulonephritis 10.69 9.55 7 427252 151 110161889
Acute pulmonary histoplasmosis 10.69 9.55 9 427250 288 110161752
Incontinence 10.67 9.55 31 427228 16604 110145436
Achromobacter infection 10.66 9.55 9 427250 289 110161751
Complement factor C3 decreased 10.63 9.55 10 427249 371 110161669
Apnoea 10.63 9.55 23 427236 13616 110148424
Allergy to plants 10.63 9.55 15 427244 868 110161172
Eyelid sensory disorder 10.62 9.55 6 427253 98 110161942
Histiocytic sarcoma 10.62 9.55 6 427253 98 110161942
Cavernous sinus thrombosis 10.61 9.55 11 427248 460 110161580
Infusion related hypersensitivity reaction 10.60 9.55 15 427244 870 110161170
Infection 10.59 9.55 1231 426028 360969 109801071
Ophthalmoplegia 10.58 9.55 34 427225 3516 110158524
Dental caries 10.57 9.55 85 427174 12688 110149352
Measles 10.55 9.55 13 427246 658 110161382
Gangrene 10.55 9.55 103 427156 16238 110145802
Granulicatella bacteraemia 10.55 9.55 4 427255 24 110162016
Ventricular tachycardia 10.55 9.55 133 427126 49876 110112164
Klebsiella bacteraemia 10.55 9.55 42 427217 4827 110157213
Chorioretinal scar 10.52 9.55 6 427253 100 110161940
Nephrogenic systemic fibrosis 10.52 9.55 4 427255 5479 110156561
Panic attack 10.50 9.55 67 427192 28873 110133167
Neurosarcoidosis 10.50 9.55 11 427248 466 110161574
Ejection fraction decreased 10.49 9.55 104 427155 40776 110121264
Extrasystoles 10.46 9.55 10 427249 8308 110153732
Pulmonary interstitial emphysema syndrome 10.46 9.55 12 427247 563 110161477
Magnesium deficiency 10.45 9.55 14 427245 771 110161269
Renal cell carcinoma 10.43 9.55 57 427202 7473 110154567
Acid base balance abnormal 10.42 9.55 11 427248 470 110161570
Bone giant cell tumour 10.41 9.55 6 427253 102 110161938
Viral load abnormal 10.41 9.55 6 427253 102 110161938
Portal vein embolism 10.41 9.55 6 427253 102 110161938
Coxsackie myocarditis 10.41 9.55 3 427256 6 110162034
Parenteral nutrition 10.41 9.55 15 427244 885 110161155
Neuritis 10.40 9.55 8 427251 7391 110154649
Paraparesis 10.39 9.55 40 427219 4526 110157514
Ureteric obstruction 10.37 9.55 31 427228 3083 110158957
Anorectal malformation 10.36 9.55 5 427254 58 110161982
Cystitis escherichia 10.32 9.55 14 427245 780 110161260
Colon cancer 10.29 9.55 31 427228 16412 110145628
Transfusion 10.29 9.55 57 427202 25415 110136625
Acute haemorrhagic leukoencephalitis 10.28 9.55 4 427255 26 110162014
Vaccination site inflammation 10.28 9.55 5 427254 59 110161981
CD8 lymphocytes decreased 10.27 9.55 9 427250 304 110161736
Acute hepatic failure 10.27 9.55 198 427061 36270 110125770
Gastric perforation 10.26 9.55 42 427217 4887 110157153
Splenic infection fungal 10.26 9.55 7 427252 162 110161878
Rash erythematous 10.26 9.55 400 426859 81432 110080608
Stomatitis necrotising 10.26 9.55 8 427251 229 110161811
Gastrointestinal ulcer 10.26 9.55 38 427221 4222 110157818
Gout 10.25 9.55 91 427168 36475 110125565
Dermatitis acneiform 10.23 9.55 21 427238 12674 110149366
Graft versus host disease in lung 10.22 9.55 18 427241 1260 110160780
Hyperbilirubinaemia 10.22 9.55 171 427088 30500 110131540
Biopsy lymph gland 10.21 9.55 6 427253 106 110161934
Bacterial tracheitis 10.21 9.55 6 427253 106 110161934
Hepatitis A 10.20 9.55 17 427242 1138 110160902
Pallor 10.19 9.55 155 427104 56312 110105728
Optic nerve operation 10.18 9.55 11 427248 483 110161557
Clubbing 10.17 9.55 14 427245 791 110161249
Ureteral disorder 10.16 9.55 12 427247 581 110161459
Foot operation 10.16 9.55 8 427251 7305 110154735
Cervical spinal cord paralysis 10.15 9.55 4 427255 27 110162013
Meningitis staphylococcal 10.14 9.55 8 427251 233 110161807
Chorioretinitis 10.14 9.55 19 427240 1396 110160644
Chromaturia 10.13 9.55 69 427190 29291 110132749
Tooth injury 10.13 9.55 25 427234 2221 110159819
International normalised ratio abnormal 10.10 9.55 6 427253 6351 110155689
Stridor 10.10 9.55 53 427206 6842 110155198
Blood catecholamines abnormal 10.10 9.55 3 427256 7 110162033
Liver function test 10.00 9.55 7 427252 169 110161871
Spinal stroke 9.99 9.55 5 427254 63 110161977
Haemorrhagic necrotic pancreatitis 9.97 9.55 7 427252 170 110161870
Insurance issue 9.95 9.55 16 427243 10596 110151444
Infective tenosynovitis 9.94 9.55 11 427248 496 110161544
Personality change 9.93 9.55 17 427242 10985 110151055
Skin hyperplasia 9.92 9.55 5 427254 64 110161976
Right ventricle outflow tract obstruction 9.92 9.55 5 427254 64 110161976
Vascular rupture 9.91 9.55 22 427237 1824 110160216
Left ventricular failure 9.91 9.55 18 427241 11371 110150669
Optic nerve compression 9.91 9.55 4 427255 29 110162011
Dysbiosis 9.90 9.55 24 427235 2108 110159932
Probiotic therapy 9.90 9.55 7 427252 172 110161868
Bowel movement irregularity 9.88 9.55 9 427250 7651 110154389
Acute interstitial pneumonitis 9.84 9.55 19 427240 1427 110160613
Mycobacterium haemophilum infection 9.84 9.55 13 427246 706 110161334
Sneezing 9.82 9.55 176 427083 31808 110130232
Interleukin-2 receptor increased 9.82 9.55 9 427250 323 110161717
Herpes zoster meningoradiculitis 9.81 9.55 3 427256 8 110162032
Tracheitis 9.80 9.55 21 427238 1700 110160340
Bradyphrenia 9.80 9.55 19 427240 11709 110150331
Alanine aminotransferase abnormal 9.80 9.55 13 427246 9321 110152719
Infusion site mobility decreased 9.79 9.55 5 427254 66 110161974
Monocyte percentage decreased 9.77 9.55 9 427250 325 110161715
Pulmonary necrosis 9.76 9.55 12 427247 606 110161434
Pulse pressure increased 9.76 9.55 7 427252 176 110161864
Eosinophil count abnormal 9.74 9.55 16 427243 1058 110160982
Balance disorder 9.74 9.55 360 426899 116200 110045840
Faeces discoloured 9.73 9.55 84 427175 33864 110128176
Leiomyoma 9.73 9.55 10 427249 414 110161626
Radiculopathy 9.72 9.55 40 427219 19296 110142744
Pain of skin 9.72 9.55 42 427217 19987 110142053
Chronic graft versus host disease in eye 9.71 9.55 10 427249 415 110161625
Acanthamoeba infection 9.69 9.55 12 427247 611 110161429
Drooling 9.68 9.55 8 427251 7131 110154909
Arteritis infective 9.65 9.55 7 427252 179 110161861
Herpes zoster infection neurological 9.64 9.55 11 427248 513 110161527
Muscle abscess 9.63 9.55 19 427240 1450 110160590
Viral myocarditis 9.63 9.55 13 427246 721 110161319
Lichenoid keratosis 9.62 9.55 49 427210 6253 110155787
General symptom 9.62 9.55 12 427247 8834 110153206
Viral myositis 9.59 9.55 5 427254 69 110161971
Paralogism 9.58 9.55 4 427255 32 110162008
Angina unstable 9.56 9.55 32 427227 16400 110145640
Renal disorder 9.56 9.55 134 427125 49345 110112695
Herpes simplex necrotising retinopathy 9.56 9.55 3 427256 9 110162031
Haematopoietic stem cell mobilisation 9.55 9.55 10 427249 423 110161617
Orbital infection 9.55 9.55 7 427252 182 110161858

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D07AA01 DERMATOLOGICALS
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
CORTICOSTEROIDS, PLAIN
Corticosteroids, weak (group I)
ATC D07CA02 DERMATOLOGICALS
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
Corticosteroids, weak, combinations with antibiotics
ATC D10AA02 DERMATOLOGICALS
ANTI-ACNE PREPARATIONS
ANTI-ACNE PREPARATIONS FOR TOPICAL USE
Corticosteroids, combinations for treatment of acne
ATC H02AB04 SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
CORTICOSTEROIDS FOR SYSTEMIC USE
CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
Glucocorticoids
ATC H02BX01 SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
CORTICOSTEROIDS FOR SYSTEMIC USE
CORTICOSTEROIDS FOR SYSTEMIC USE, COMBINATIONS
Corticosteroids for systemic use, combinations
ATC S01CA08 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
Corticosteroids and antiinfectives in combination
ATC S03CA07 SENSORY ORGANS
OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION
Corticosteroids and antiinfectives in combination
FDA MoA N0000175450 Corticosteroid Hormone Receptor Agonists
FDA EPC N0000175576 Corticosteroid
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000932 Antiemetics
MeSH PA D005765 Gastrointestinal Agents
MeSH PA D005938 Glucocorticoids
MeSH PA D006728 Hormones
MeSH PA D018696 Neuroprotective Agents
MeSH PA D020011 Protective Agents
CHEBI has role CHEBI:35472 anti-inflammatory drugs
CHEBI has role CHEBI:35703 Xenobiotic
CHEBI has role CHEBI:37962 adrenergic agents
CHEBI has role CHEBI:50919 antiemetico
CHEBI has role CHEBI:63726 neuroprotective agents
CHEBI has role CHEBI:78298 environmental contaminants

Related Drugs by ATC class:

D07AA Corticosteroids, weak (group I) 2 drugs
hydrocortisoneprednisolone
D07CA Corticosteroids, weak, combinations with antibiotics 2 drugs
hydrocortisoneprednisolone
D10AA Corticosteroids, combinations for treatment of acne 2 drugs
dexamethasonefluorometholone
H02AB Glucocorticoids 15 drugs
betamethasonecloprednolcortivazoldeflazacortdexamethasonefluocortolonehydrocortisonemeprednisoneparamethasone acetateprednisoloneprednisoneprednylidene show all 15 →
S01CA Corticosteroids and antiinfectives in combination 11 drugs
betamethasonechloroprednisoneclobetasone butyratedexamethasonefludrocortisone acetatefluocinolone acetonidefluocortolonefluorometholonehydrocortisoneloteprednol etabonateprednisolone
S03CA Corticosteroids and antiinfectives in combination 5 drugs
betamethasonedexamethasonefludrocortisone acetatehydrocortisoneprednisolone

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Disorder of musculoskeletal system indication 928000 DOID:17
Cerebral edema indication 2032001
Berylliosis indication 8247009 DOID:10322
Psoriasis indication 9014002 DOID:8893
Ankylosing spondylitis indication 9631008 DOID:7147
Rheumatic heart disease indication 23685000
Atopic dermatitis indication 24079001 DOID:3310
Inflammatory bowel disease indication 24526004 DOID:0050589
Multiple sclerosis indication 24700007 DOID:2377
Severe adrenal insufficiency indication 24867002
Sarcoidosis indication 31541009 DOID:11335
Idiopathic thrombocytopenic purpura indication 32273002 DOID:8924
Psoriasis with arthropathy indication 33339001
Crohn's disease indication 34000006
Tendinitis indication 34840004 DOID:971
Erythema multiforme indication 36715001
Contact dermatitis indication 40275004 DOID:2773
Angioedema indication 41291007 DOID:1558
Miliary tuberculosis indication 47604008 DOID:9861
Humoral hypercalcemia of malignancy indication 47709007
Articular gout indication 48440001 DOID:13189
Seborrheic dermatitis indication 50563003 DOID:8741
Edema of larynx indication 51599000
Nephrotic syndrome indication 52254009 DOID:1184
Lichen simplex chronicus indication 53891004
Systemic lupus erythematosus indication 55464009 DOID:9074
Allergic rhinitis indication 61582004
Löffler's syndrome indication 64936001 DOID:9503
Pemphigus indication 65172003 DOID:9182
Granuloma annulare indication 65508009 DOID:3777
Tenosynovitis indication 67801009 DOID:970
Rheumatoid arthritis indication 69896004 DOID:7148
Transfusion reaction due to serum protein reaction indication 72284000
Epicondylitis indication 73583000 DOID:14087
Acquired thrombocytopenia indication 74576004 DOID:11126
Thyroiditis indication 82119001 DOID:7166
Bursitis indication 84017003 DOID:2965
Autoimmune disease indication 85828009
Infection by larvae of Trichinella spiralis indication 88264003
Congenital hypoplastic anemia indication 88854002 DOID:1339
Pruritus ani indication 90446007
Acute lymphoid leukemia indication 91857003 DOID:9952
Disorder of skin indication 95320005 DOID:37
Dermatitis herpetiformis indication 111196000 DOID:8505
Hodgkin's disease indication 118599009
Non-Hodgkin's lymphoma indication 118601006
Mycosis fungoides indication 118618005
Aspiration pneumonitis indication 155597006
Asthma indication 195967001 DOID:2841
Discoid lupus erythematosus indication 200938002
Plaque psoriasis indication 200965009
Transplanted organ rejection indication 213148006
Congenital adrenal hyperplasia indication 237751000
Scalp psoriasis indication 238608008
Adrenogenital disorder indication 267395000 DOID:0050811
Pruritus of genital organs indication 267802000
Eruption of skin indication 271807003 DOID:0050486
Exacerbation of asthma indication 281239006
Follicular non-Hodgkin's lymphoma indication 308121000
Disorder of eye indication 371405004 DOID:5614
Primary adrenocortical insufficiency indication 373662000
Adrenal cortical hypofunction indication 386584007 DOID:10493
Erythroderma indication 399992009
Primary cutaneous T-cell lymphoma indication 400122007
Juvenile rheumatoid arthritis indication 410795001
Autoimmune hemolytic anemia indication 413603009 DOID:718
Synovitis indication 416209007 DOID:2703
Post traumatic osteoarthritis indication 699262001
Systemic Dermatomyositis indication
Diagnostic Test for Cushing's Syndrome indication
Synovitis due to Osteoarthritis indication
Transfusion Reaction Urticaria indication
Progressive Diffuse Large B-Cell Lymphoma indication
Erythroblastic Anemia indication
Pericarditis off-label use 3238004 DOID:1787
Chronic obstructive lung disease off-label use 13645005 DOID:3083
Pulmonary edema off-label use 19242006 DOID:11396
Shock off-label use 27942005
West syndrome off-label use 28055006
Vasculitis off-label use 31996006 DOID:865
Bronchitis off-label use 32398004 DOID:6132
Anaphylaxis off-label use 39579001
Eczema off-label use 43116000
Respiratory distress syndrome in the newborn off-label use 46775006
Nasal polyp off-label use 52756005
Rheumatic fever off-label use 58718002 DOID:1586
Pseudogout off-label use 60782007
Polymyalgia rheumatica off-label use 65323003 DOID:853
Chronic hepatitis off-label use 76783007 DOID:2237
Pemphigoid off-label use 86142006
Hepatic necrosis off-label use 87248009
Multiple myeloma off-label use 109989006 DOID:9538
Polyarteritis nodosa off-label use 155441006 DOID:9810
Coronavirus infection off-label use 186747009
Celiac disease off-label use 396331005 DOID:10608
Carditis off-label use 399617002
Giant cell arteritis off-label use 414341000 DOID:13375
Neonatal Bronchopulmonary Dysplasia off-label use
Prevention of Post-Extubation Laryngeal Edema off-label use
Metastatic Prostate Carcinoma off-label use
Hypercalcemia associated with Sarcoidosis off-label use
Neuroendocrine Prostate Carcinoma off-label use
Prevention of Lung Transplant Rejection off-label use
Prevention of Cardiac Transplant Rejection off-label use
Infection by Strongyloides contraindication 1214006 DOID:10955
Mycosis contraindication 3218000 DOID:1564
Gastritis contraindication 4556007 DOID:4029
Inactive tuberculosis contraindication 11999007
Peptic ulcer contraindication 13200003 DOID:750
Hypercholesterolemia contraindication 13644009
Measles contraindication 14189004 DOID:8622
Cirrhosis of liver contraindication 19943007 DOID:5082
Arginase deficiency contraindication 23501004 DOID:9278
Immunosuppression contraindication 38013005
Hypertensive disorder contraindication 38341003 DOID:10763
Infectious disease contraindication 40733004
Hypothyroidism contraindication 40930008 DOID:1459
Hypokalemia contraindication 43339004
Chronic heart failure contraindication 48447003
Cerebral malaria contraindication 53622003 DOID:14069
Tuberculosis contraindication 56717001
Congenital hyperammonemia, type I contraindication 62522004
Osteoporosis contraindication 64859006 DOID:11476
Psychotic disorder contraindication 69322001
Diabetes mellitus contraindication 73211009 DOID:9351
Hypopituitarism contraindication 74728003 DOID:9406
Hyperglycemia contraindication 80394007 DOID:4195
Ornithine Carbamyltransferase Deficiency contraindication 80908008 DOID:9271
Open-angle glaucoma contraindication 84494001 DOID:1067
Muscle atrophy contraindication 88092000 DOID:767
Herpes simplex contraindication 88594005 DOID:8566
Bilateral cataracts contraindication 95722004
Seizure disorder contraindication 128613002
Disorder of muscle contraindication 129565002 DOID:423
Ophthalmic herpes simplex contraindication 186542001
Skin striae contraindication 201066002
Anastomosis of intestine contraindication 235407009
Telangiectasia disorder contraindication 247479008
Edema contraindication 267038008
Pathological fracture contraindication 268029009
Diverticulitis of gastrointestinal tract contraindication 271366000
Cerebral trauma contraindication 275382005
Pregnancy, function contraindication 289908002
Varicella-zoster virus infection contraindication 309465005
Osteopenia contraindication 312894000
Avascular necrosis of bone contraindication 397758007 DOID:10159
Citrullinemia contraindication 398680004 DOID:9273
Atrophoderma contraindication 399979006
Traumatic rupture of tendon contraindication 415749005
Exposure to varicella contraindication 444453009
Arginosuccinate Lyase Deficiency contraindication




🐶 Veterinary Drug Use

SpeciesUseRelation
Cats Inflammation and related disorders Indication
Cats Allergic and dermatologic disorders Indication
Cats Supportive therapy to antibacterial treatment of severe infections Indication
Dogs Inflammation and related disorders Indication
Dogs Allergic and dermatologic disorders Indication
Dogs Supportive therapy to antibacterial treatment of severe infections Indication
Horses Inflammation and related disorders Indication

🐶 Veterinary products

ProductApplicantIngredients
Medrol Tablets Zoetis Inc. 1
Cortaba Tablets Zoetis Inc. 2
Methylprednisolene Tablets Cronus Pharma Specialities India Private Limited 1

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.18 acidic
pKa2 12.89 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Glucocorticoid receptor Nuclear hormone receptor AGONIST EC50 8.50 WOMBAT-PK CHEMBL
Annexin A1 Cytosolic other WOMBAT-PK
Short transient receptor potential channel 5 Ion channel ACTIVATOR EC50 4.92 IUPHAR
Androgen receptor Transcription factor Ki 4.75 DRUG MATRIX

External reference:

IDSource
4018068 VUID
N0000146409 NUI
D00407 KEGG_DRUG
4018068 VANDF
C0025815 UMLSCUI
CHEBI:6888 CHEBI
CHEMBL650 ChEMBL_ID
DB00959 DRUGBANK_ID
D008775 MESH_DESCRIPTOR_UI
6741 PUBCHEM_CID
7088 IUPHAR_LIGAND_ID
732 INN_ID
X4W7ZR7023 UNII
6902 RXNORM
1041 MMSL
5093 MMSL
7130 MMSL
d00293 MMSL
002160 NDDF
116593003 SNOMEDCT_US
27242001 SNOMEDCT_US
X4W7ZR7023 INXIGHT DRUGS

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0009-0020 TABLET 2 mg ORAL NDA 16 sections
Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0009-0022 TABLET 8 mg ORAL NDA 16 sections
Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0009-0049 TABLET 2 mg ORAL NDA 16 sections
Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0009-0056 TABLET 4 mg ORAL NDA 16 sections
Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0009-0073 TABLET 16 mg ORAL NDA 16 sections
Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0009-0176 TABLET 32 mg ORAL NDA 16 sections
MethylPREDNISolone HUMAN PRESCRIPTION DRUG LABEL 1 0603-4593 TABLET 4 mg ORAL ANDA 14 sections
methylprednisolone HUMAN PRESCRIPTION DRUG LABEL 1 0904-6914 TABLET 4 mg ORAL ANDA 13 sections
METHYLPREDNISOLONE HUMAN PRESCRIPTION DRUG LABEL 1 16590-149 TABLET 4 mg ORAL ANDA 11 sections
Medrol HUMAN PRESCRIPTION DRUG LABEL 1 16590-879 TABLET 4 mg ORAL NDA 11 sections
Methylprednisolone HUMAN PRESCRIPTION DRUG LABEL 1 21695-080 TABLET 4 mg ORAL ANDA 12 sections
Methylprednisolone HUMAN PRESCRIPTION DRUG LABEL 1 33261-335 TABLET 4 mg ORAL ANDA 12 sections
METHYLPREDNISOLONE HUMAN PRESCRIPTION DRUG LABEL 1 42549-522 TABLET 4 mg ORAL ANDA 12 sections
METHYLPREDNISOLONE HUMAN PRESCRIPTION DRUG LABEL 1 42806-400 TABLET 4 mg ORAL ANDA 16 sections
Methylprednisolone HUMAN PRESCRIPTION DRUG LABEL 1 45865-104 TABLET 4 mg ORAL ANDA 15 sections
Methylprednisolone HUMAN PRESCRIPTION DRUG LABEL 1 45865-417 TABLET 4 mg ORAL ANDA 12 sections
Medrol HUMAN PRESCRIPTION DRUG LABEL 1 50090-0092 TABLET 4 mg ORAL NDA 15 sections
Methylprednisolone HUMAN PRESCRIPTION DRUG LABEL 1 50090-3094 TABLET 4 mg ORAL ANDA 12 sections
methylprednisolone HUMAN PRESCRIPTION DRUG LABEL 1 50090-3811 TABLET 4 mg ORAL ANDA 12 sections
Methylprednisolone HUMAN PRESCRIPTION DRUG LABEL 1 50436-0001 TABLET 4 mg ORAL ANDA 12 sections
METHYLPREDNISOLONE HUMAN PRESCRIPTION DRUG LABEL 1 50436-0015 TABLET 4 mg ORAL ANDA 15 sections
Methylprednisolone HUMAN PRESCRIPTION DRUG LABEL 1 50436-4037 TABLET 4 mg ORAL ANDA 12 sections
Methylprednisolone HUMAN PRESCRIPTION DRUG LABEL 1 53002-3120 TABLET 4 mg ORAL ANDA 12 sections
Methylprednisolone HUMAN PRESCRIPTION DRUG LABEL 1 53002-3121 TABLET 4 mg ORAL ANDA 14 sections
METHYLPREDNISOLONE HUMAN PRESCRIPTION DRUG LABEL 1 53002-3122 TABLET 4 mg ORAL ANDA 15 sections
Methylprednisolone HUMAN PRESCRIPTION DRUG LABEL 1 54868-2913 TABLET 4 mg ORAL ANDA 11 sections
METHYLPREDNISOLONE HUMAN PRESCRIPTION DRUG LABEL 1 54868-6624 TABLET 4 mg ORAL ANDA 12 sections
MethylPREDNISolone HUMAN PRESCRIPTION DRUG LABEL 1 55045-1259 TABLET 4 mg ORAL ANDA 17 sections
MethylPREDNISolone HUMAN PRESCRIPTION DRUG LABEL 1 55289-649 TABLET 4 mg ORAL ANDA 14 sections
METHYLPREDNISOLONE HUMAN PRESCRIPTION DRUG LABEL 1 57582-101 TABLET 4 mg ORAL ANDA 16 sections