calcium glubionate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4842 12569-38-9

Description:

MoleculeDescription

Synonyms:

  • calcium glubionate
  • Neo-Calglucon
  • calcium glubionate monohydrate
  • Molecular weight: 610.53
  • Formula: C18H34CaO20
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 220.43
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Liver injury 1024.16 198.93 1257 131939 169310 90325941
Psoriatic arthropathy 964.08 198.93 1417 131779 226918 90268333
Type 2 diabetes mellitus 785.93 198.93 1211 131985 202033 90293218
Fibromyalgia 714.74 198.93 1169 132027 205100 90290151
Rheumatic fever 675.78 198.93 971 132225 152150 90343101
Helicobacter infection 667.97 198.93 1196 132000 225654 90269597
Blood cholesterol increased 654.24 198.93 1129 132067 206883 90288368
Hand deformity 652.67 198.93 1382 131814 294980 90200271
Duodenal ulcer perforation 644.25 198.93 1161 132035 220127 90275124
Injury 629.62 198.93 1078 132118 196271 90298980
Glossodynia 609.86 198.93 1413 131783 320366 90174885
Hypercholesterolaemia 607.26 198.93 745 132451 100147 90395104
Joint range of motion decreased 566.21 198.93 838 132358 134805 90360446
Pemphigus 561.80 198.93 1382 131814 325482 90169769
Folliculitis 551.66 198.93 1038 132158 203315 90291936
Facet joint syndrome 549.73 198.93 700 132496 97689 90397562
Wound 545.18 198.93 1304 131892 301676 90193575
Pericarditis 542.37 198.93 1214 131982 268937 90226314
Grip strength decreased 535.24 198.93 670 132526 91906 90403345
Cough 519.71 198.93 4 133192 368958 90126293
Systemic lupus erythematosus 505.35 198.93 1416 131780 360480 90134771
Lip dry 497.03 198.93 675 132521 100280 90394971
Mobility decreased 474.60 198.93 1101 132095 249633 90245618
Swollen joint count increased 472.60 198.93 693 132503 110513 90384738
Wound infection 457.85 198.93 667 132529 105735 90389516
Irritable bowel syndrome 456.87 198.93 968 132228 206480 90288771
Muscle injury 455.27 198.93 880 132316 175774 90319477
Anti-cyclic citrullinated peptide antibody positive 442.81 198.93 1034 132162 235399 90259852
Rheumatoid arthritis 441.17 198.93 1351 131845 361263 90133988
Deep vein thrombosis postoperative 440.77 198.93 532 132664 70277 90424974
Impaired healing 427.45 198.93 1014 132182 233185 90262066
Blister 427.03 198.93 1068 132128 253930 90241321
Adjustment disorder with depressed mood 419.68 198.93 466 132730 56287 90438964
Gait inability 411.34 198.93 757 132439 145699 90349552
Autoimmune disorder 409.76 198.93 534 132662 76210 90419041
Rheumatoid factor positive 409.60 198.93 828 132368 170822 90324429
Arthropathy 402.86 198.93 1318 131878 364924 90130327
Breast cancer stage III 390.62 198.93 548 132648 83899 90411352
Synovitis 371.85 198.93 1197 131999 328555 90166696
Hypotension 368.71 198.93 29 133167 325368 90169883
Back pain 357.33 198.93 29 133167 317146 90178105
Pulmonary fibrosis 356.67 198.93 598 132598 106905 90388346
Sleep disorder 355.37 198.93 852 132344 197178 90298073
Bursitis 347.83 198.93 663 132533 130991 90364260
C-reactive protein abnormal 335.75 198.93 641 132555 126788 90368463
Dislocation of vertebra 334.48 198.93 412 132784 55556 90439695
Wheezing 331.25 198.93 931 132265 237149 90258102
Stomatitis 330.52 198.93 1020 132176 273678 90221573
Peripheral venous disease 326.52 198.93 502 132694 83419 90411832
Hypoaesthesia 323.33 198.93 1106 132090 313104 90182147
General physical health deterioration 316.07 198.93 1192 132004 353923 90141328
Erythema 315.60 198.93 4 133192 229242 90266009
Lower limb fracture 309.17 198.93 493 132703 84520 90410731
Road traffic accident 295.42 198.93 551 132645 107075 90388176
Dyspepsia 293.53 198.93 793 132403 197367 90297884
Fall 288.17 198.93 176 133020 481634 90013617
Discomfort 278.93 198.93 962 132234 273373 90221878
Hepatic enzyme increased 277.56 198.93 1157 132039 359579 90135672
Urticaria 273.42 198.93 1044 132152 311690 90183561
X-ray abnormal 272.40 198.93 335 132861 45089 90450162
Swelling 269.54 198.93 1274 131922 417784 90077467
Sciatica 265.79 198.93 509 132687 100873 90394378
Breast cancer stage II 264.39 198.93 292 132904 35042 90460209
Obesity 261.13 198.93 517 132679 104990 90390261
Drug ineffective 260.14 198.93 1102 132094 1383196 89112055
Sleep disorder due to general medical condition, insomnia type 258.50 198.93 579 132617 128115 90367136
Blood pressure increased 257.09 198.93 7 133189 197210 90298041
Musculoskeletal stiffness 255.97 198.93 986 132210 295546 90199705
Lupus vulgaris 253.72 198.93 322 132874 44737 90450514
Prescribed underdose 249.67 198.93 418 132778 74601 90420650
Death 243.40 198.93 189 133007 456362 90038889
Anti-cyclic citrullinated peptide antibody 242.79 198.93 247 132949 26974 90468277
Bone erosion 239.07 198.93 340 132856 52681 90442570
Myalgia 232.91 198.93 5 133191 175120 90320131
Dry mouth 229.16 198.93 692 132504 183367 90311884
Ill-defined disorder 226.32 198.93 691 132505 184200 90311051
Feeling abnormal 225.53 198.93 4 133192 167231 90328020
Alopecia 225.48 198.93 1369 131827 493702 90001549
Prescribed overdose 224.46 198.93 464 132732 97161 90398090
Haemoglobin decreased 222.11 198.93 3 133193 161953 90333298
Lower respiratory tract infection 221.60 198.93 840 132356 249819 90245432
Blepharospasm 217.49 198.93 333 132863 55112 90440139
Osteoarthritis 213.49 198.93 703 132493 195027 90300224
Nail disorder 209.86 198.93 339 132857 58728 90436523
White blood cell count decreased 207.05 198.93 9 133187 167100 90328151
Infusion related reaction 204.80 198.93 1176 132020 415604 90079647
Night sweats 204.46 198.93 529 132667 128237 90367014
Abdominal discomfort 201.70 198.93 1295 131901 476033 90019218

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Psoriatic arthropathy 858.93 291.08 995 104039 195766 110288499
Type 2 diabetes mellitus 844.49 291.08 938 104096 176294 110307971
Fibromyalgia 835.85 291.08 917 104117 169992 110314273
Helicobacter infection 826.30 291.08 939 104095 180938 110303327
Hand deformity 824.43 291.08 1026 104008 217480 110266785
Liver injury 818.30 291.08 854 104180 149559 110334706
Facet joint syndrome 798.27 291.08 692 104342 96136 110388129
Rheumatic fever 797.45 291.08 767 104267 121812 110362453
Duodenal ulcer perforation 787.89 291.08 906 104128 176794 110307471
Glossodynia 767.30 291.08 998 104036 221006 110263259
Lip dry 725.25 291.08 665 104369 99418 110384847
Pemphigus 720.40 291.08 951 104083 213619 110270646
Systemic lupus erythematosus 714.07 291.08 1034 104000 253304 110230961
Folliculitis 703.43 291.08 831 104203 166822 110317443
Blood cholesterol increased 689.31 291.08 863 104171 183922 110300343
Wound 666.63 291.08 959 104075 233478 110250787
Pericarditis 659.44 291.08 921 104113 218193 110266072
Injury 615.51 291.08 799 104235 176466 110307799
Joint range of motion decreased 604.53 291.08 659 104375 121173 110363092
Anti-cyclic citrullinated peptide antibody positive 595.90 291.08 797 104237 181187 110303078
Muscle injury 590.61 291.08 698 104336 140109 110344156
Irritable bowel syndrome 571.35 291.08 741 104293 163474 110320791
Synovitis 559.41 291.08 963 104071 273129 110211136
Swollen joint count increased 556.18 291.08 530 104504 83131 110401134
Grip strength decreased 550.33 291.08 517 104517 79657 110404608
C-reactive protein abnormal 540.72 291.08 641 104393 129054 110355211
Bursitis 539.82 291.08 641 104393 129277 110354988
Mobility decreased 536.22 291.08 873 104161 236549 110247716
Blister 524.29 291.08 844 104190 226532 110257733
Impaired healing 523.19 291.08 780 104254 195937 110288328
Rheumatoid arthritis 510.07 291.08 973 104061 298640 110185625
Breast cancer stage III 504.72 291.08 490 104544 78627 110405638
Rheumatoid factor positive 492.52 291.08 616 104418 131024 110353241
Hypercholesterolaemia 485.12 291.08 511 104523 90326 110393939
Deep vein thrombosis postoperative 482.88 291.08 421 104613 58870 110425395
Peripheral venous disease 468.56 291.08 484 104550 83633 110400632
Wound infection 464.91 291.08 514 104520 95951 110388314
Arthropathy 444.74 291.08 897 104137 286625 110197640
Stomatitis 417.80 291.08 843 104191 269399 110214866
Sleep disorder 416.94 291.08 707 104327 197937 110286328
Cough 416.56 291.08 4 105030 461637 110022628
Autoimmune disorder 407.22 291.08 400 104634 65083 110419182
Swelling 401.24 291.08 970 104064 350071 110134194
Obesity 401.11 291.08 516 104518 112835 110371430
Hepatic enzyme increased 396.36 291.08 914 104120 319978 110164287
Gait inability 394.70 291.08 563 104471 135813 110348452
Ill-defined disorder 394.26 291.08 606 104428 156247 110328018
Hypotension 390.02 291.08 28 105006 523821 109960444
Dry mouth 377.16 291.08 679 104355 199269 110284996
Adjustment disorder with depressed mood 376.36 291.08 321 104713 43562 110440703
Alopecia 375.98 291.08 969 104065 363784 110120481
Wheezing 355.58 291.08 763 104271 254467 110229798
Lower limb fracture 355.27 291.08 397 104637 74951 110409314
Osteoarthritis 354.46 291.08 628 104406 181995 110302270
Road traffic accident 352.22 291.08 471 104563 106927 110377338
Sleep disorder due to general medical condition, insomnia type 350.59 291.08 466 104568 105177 110379088
Night sweats 348.47 291.08 526 104508 133457 110350808
Sciatica 348.06 291.08 434 104600 91965 110392300
Lower respiratory tract infection 344.69 291.08 732 104302 242374 110241891
Hypoaesthesia 333.28 291.08 844 104190 313379 110170886
Nail disorder 332.79 291.08 339 104695 57596 110426669
Discomfort 329.57 291.08 668 104366 214039 110270226
Inflammation 321.64 291.08 622 104412 192616 110291649
Maternal exposure during pregnancy 307.96 291.08 720 104314 254163 110230102
Blepharospasm 306.07 291.08 316 104718 54535 110429730
X-ray abnormal 302.96 291.08 267 104767 37850 110446415
Live birth 296.97 291.08 348 104686 69136 110415129
Urticaria 294.94 291.08 814 104220 318043 110166222
Dyspepsia 292.86 291.08 594 104440 190371 110293894

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A12AA02 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
CALCIUM
Calcium

Related Drugs by ATC class:

A12AA Calcium 11 drugs
calcium carbonatecalcium chloridecalcium citratecalcium glucoheptonatecalcium gluconatecalcium glycerylphosphatecalcium lactatecalcium lactate gluconatecalcium levulinatecalcium pangamatecalcium phosphate

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypocalcemia indication 5291005




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
3CF7K0SD0Q UNII
D03294 KEGG_DRUG
4020041 VUID
N0000179144 NUI
4020041 VANDF
C0061347 UMLSCUI
CHEBI:750927 CHEBI
CHEMBL2104594 ChEMBL_ID
6093269 PUBCHEM_CID
2890 INN_ID
C042131 MESH_SUPPLEMENTAL_RECORD_UI
218656 RXNORM
4335 MMSL
5173 MMSL
8444 MMSL
d03817 MMSL
000775 NDDF
32445001 SNOMEDCT_US

Pharmaceutical products:

None