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| Stem definition | Drug id | CAS RN |
|---|---|---|
| acetylcholinesterase inhibitors | 1897 | 59-99-4 |
| Dose | Unit | Route |
|---|---|---|
| 60 | mg | O |
| 2 | mg | P |
| 0.40 | ml | None |
| 40 | mg | ointment |
| Property | Value | Reference |
|---|---|---|
| BDDCS (Biopharmaceutical Drug Disposition Classification System) | 3 | Benet LZ, Broccatelli F, Oprea TI |
| S (Water solubility) | 100 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
| EoM (Fraction excreted unchanged in urine) | 67 % | Benet LZ, Broccatelli F, Oprea TI |
| MRTD (Maximum Recommended Therapeutic Daily Dose) | 0.12 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
| BA (Bioavailability) | 2 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
| Vd (Volume of distribution) | 0.74 L/kg | Lombardo F, Berellini G, Obach RS |
| CL (Clearance) | 9.20 mL/min/kg | Lombardo F, Berellini G, Obach RS |
| t_half (Half-life) | 1.30 hours | Lombardo F, Berellini G, Obach RS |
| fu (Fraction unbound in plasma) | 1 % | Kawashima H, Watanabe R, Esaki T, Kuroda M, Nagao C, Natsume-Kitatani Y, Ohashi R, Komura H, Mizuguchi K |
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| azlogd74 | LogD at pH 7.4 | -2.710 | High | 1 | |
| caco2-efflux | Caco-2 efflux ratio (BA/AB) | 2.018 | High | 1 | |
| caco2-intrinsic-papp | Caco-2 intrinsic apparent permeability | 0.230 | 10^-6 cm/s | High | 1 |
| dh-clint | Dog hepatocyte intrinsic clearance | 2.742 | uL/min/10^6 cells | High | 1 |
| dppb | Dog plasma protein binding (% unbound) | 96.180 | % | High | 1 |
| fcs-ppb | Fetal calf serum protein binding (% unbound) | 95.050 | % | High | 1 |
| herg | hERG pIC50 | 4.363 | pIC50 | High | 1 |
| hh-clint | Human hepatocyte intrinsic clearance | 0.861 | uL/min/10^6 cells | High | 1 |
| hlm-clint | Human liver microsomal intrinsic clearance | 2.951 | uL/min/mg protein | High | 1 |
| hppb | Human plasma protein binding (% unbound) | 91.890 | % | High | 1 |
| kinase-safety-class | ACVR2A,ACVR2B,AKT2,AKT3,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,ITK,JAK1,JAK2,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPK9,MAPKAPK2,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CG,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1 | 49 | |||
| kinase-selectivity-class | ACVR2B,AXL,BRAF,CSF1R,DDR1,EPHB4,ERBB2,GRK2,MAPK7,PDK4,SIK2,STK33 | 12 | |||
| mdck-mdr1-efflux | MDCK-MDR1 efflux ratio | 0.975 | High | 1 | |
| mh-clint | Mouse hepatocyte intrinsic clearance | 7.962 | High | 1 | |
| mppb | Mouse plasma protein binding (% unbound) | 96.090 | High | 1 | |
| nih-mdck-mdr1-efflux | NIH MDCK-MDR1 efflux ratio | 1.327 | High | 1 | |
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 | |||
| pppb | Pig plasma protein binding (% unbound) | 95.460 | % | High | 1 |
| rh-clint | Rat hepatocyte intrinsic clearance | 4.732 | uL/min/10^6 cells | High | 1 |
| rh-fuinc | Rat hepatocyte fraction unbound in incubation | 97.460 | % | High | 1 |
| rppb | Rat plasma protein binding (% unbound) | 95.560 | % | High | 1 |
| solubility-dd | Solubility at pH 7.4 in DMSO | 907.821 | uM | High | 1 |
| Date | Agency | Company | Orphan |
|---|---|---|---|
| May 31, 2013 | FDA | ECLAT PHARMS LLC |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Vascular encephalopathy | 96.73 | 31.12 | 17 | 2483 | 753 | 90625194 |
| Subileus | 91.37 | 31.12 | 21 | 2479 | 3623 | 90622324 |
| Schizencephaly | 73.78 | 31.12 | 12 | 2488 | 331 | 90625616 |
| Cerebral haemorrhage foetal | 73.61 | 31.12 | 12 | 2488 | 336 | 90625611 |
| Serotonin syndrome | 71.93 | 31.12 | 30 | 2470 | 37857 | 90588090 |
| Gastrointestinal sounds abnormal | 66.65 | 31.12 | 17 | 2483 | 4526 | 90621421 |
| Neuromuscular block prolonged | 66.08 | 31.12 | 12 | 2488 | 640 | 90625307 |
| Ileus | 63.81 | 31.12 | 22 | 2478 | 16524 | 90609423 |
| Negative pressure pulmonary oedema | 57.89 | 31.12 | 8 | 2492 | 69 | 90625878 |
| Stress cardiomyopathy | 56.36 | 31.12 | 19 | 2481 | 13336 | 90612611 |
| Dystonia | 55.82 | 31.12 | 20 | 2480 | 16799 | 90609148 |
| Abdominal tenderness | 54.56 | 31.12 | 17 | 2483 | 9307 | 90616640 |
| Hypotension | 54.11 | 31.12 | 55 | 2445 | 325342 | 90300605 |
| Faecaloma | 52.69 | 31.12 | 17 | 2483 | 10414 | 90615533 |
| Atrioventricular dissociation | 48.96 | 31.12 | 8 | 2492 | 227 | 90625720 |
| Apnoea | 46.15 | 31.12 | 15 | 2485 | 9399 | 90616548 |
| Procedural hypertension | 46.06 | 31.12 | 8 | 2492 | 330 | 90625617 |
| Cardiac arrest | 43.19 | 31.12 | 30 | 2470 | 104905 | 90521042 |
| Anaphylactic reaction | 43.17 | 31.12 | 28 | 2472 | 87496 | 90538451 |
| Pulmonary oedema | 41.18 | 31.12 | 24 | 2476 | 62056 | 90563891 |
| Brachial plexopathy | 40.99 | 31.12 | 7 | 2493 | 261 | 90625686 |
| Necrotising colitis | 40.52 | 31.12 | 9 | 2491 | 1329 | 90624618 |
| Dementia | 38.99 | 31.12 | 17 | 2483 | 23844 | 90602103 |
| Abdominal distension | 37.33 | 31.12 | 30 | 2470 | 130571 | 90495376 |
| White blood cell count increased | 36.85 | 31.12 | 23 | 2477 | 67218 | 90558729 |
| Bladder disorder | 36.45 | 31.12 | 13 | 2487 | 10759 | 90615188 |
| Myopia | 32.16 | 31.12 | 8 | 2492 | 1924 | 90624023 |
| Delayed recovery from anaesthesia | 31.59 | 31.12 | 7 | 2493 | 1023 | 90624924 |
| Chorea | 31.46 | 31.12 | 8 | 2492 | 2102 | 90623845 |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Serotonin syndrome | 118.80 | 34.39 | 41 | 1380 | 25804 | 42594110 |
| Bradycardia | 108.63 | 34.39 | 54 | 1367 | 85430 | 42534484 |
| Cardiac arrest | 88.01 | 34.39 | 51 | 1370 | 109269 | 42510645 |
| Drug interaction | 62.39 | 34.39 | 59 | 1362 | 266940 | 42352974 |
| Metabolic acidosis | 51.95 | 34.39 | 28 | 1393 | 51830 | 42568084 |
| Pseudomonal sepsis | 50.52 | 34.39 | 14 | 1407 | 4235 | 42615679 |
| Renal ischaemia | 47.25 | 34.39 | 11 | 1410 | 1659 | 42618255 |
| Accelerated idioventricular rhythm | 41.90 | 34.39 | 7 | 1414 | 188 | 42619726 |
| Appendicitis perforated | 39.69 | 34.39 | 10 | 1411 | 2096 | 42617818 |
| Hyperthermia malignant | 37.38 | 34.39 | 10 | 1411 | 2648 | 42617266 |
| Atrioventricular block second degree | 37.22 | 34.39 | 11 | 1410 | 4176 | 42615738 |
| Acute pulmonary oedema | 36.85 | 34.39 | 13 | 1408 | 8638 | 42611276 |
| Angle closure glaucoma | 34.98 | 34.39 | 8 | 1413 | 1114 | 42618800 |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Serotonin syndrome | 140.16 | 27.04 | 59 | 3878 | 59094 | 110526268 |
| Bradycardia | 118.80 | 27.04 | 72 | 3865 | 155445 | 110429917 |
| Cardiac arrest | 110.42 | 27.04 | 75 | 3862 | 196678 | 110388684 |
| Vascular encephalopathy | 91.22 | 27.04 | 17 | 3920 | 807 | 110584555 |
| Subileus | 74.16 | 27.04 | 21 | 3916 | 6416 | 110578946 |
| Pulmonary oedema | 70.14 | 27.04 | 44 | 3893 | 100615 | 110484747 |
| Neuromuscular block prolonged | 66.62 | 27.04 | 14 | 3923 | 1233 | 110584129 |
| Drug interaction | 63.11 | 27.04 | 83 | 3854 | 500100 | 110085262 |
| Gastrointestinal sounds abnormal | 57.61 | 27.04 | 17 | 3920 | 6001 | 110579361 |
| Ileus | 57.55 | 27.04 | 26 | 3911 | 30703 | 110554659 |
| Hypotension | 57.11 | 27.04 | 81 | 3856 | 523768 | 110061594 |
| Stress cardiomyopathy | 55.63 | 27.04 | 21 | 3916 | 15785 | 110569577 |
| Laryngospasm | 52.74 | 27.04 | 15 | 3922 | 4653 | 110580709 |
| Dystonia | 52.05 | 27.04 | 23 | 3914 | 25782 | 110559580 |
| Tachycardia | 51.34 | 27.04 | 51 | 3886 | 226594 | 110358768 |
| Apnoea | 51.20 | 27.04 | 19 | 3918 | 13620 | 110571742 |
| Abdominal tenderness | 45.47 | 27.04 | 17 | 3920 | 12440 | 110572922 |
| White blood cell count increased | 45.10 | 27.04 | 33 | 3904 | 96809 | 110488553 |
| Negative pressure pulmonary oedema | 44.05 | 27.04 | 9 | 3928 | 690 | 110584672 |
| Procedural hypertension | 43.76 | 27.04 | 8 | 3929 | 341 | 110585021 |
| Delayed recovery from anaesthesia | 43.41 | 27.04 | 11 | 3926 | 2204 | 110583158 |
| Renal ischaemia | 42.89 | 27.04 | 11 | 3926 | 2312 | 110583050 |
| Atrioventricular dissociation | 42.79 | 27.04 | 8 | 3929 | 386 | 110584976 |
| Hyperthermia malignant | 41.67 | 27.04 | 12 | 3925 | 3888 | 110581474 |
| Faecaloma | 39.06 | 27.04 | 16 | 3921 | 14892 | 110570470 |
| Accelerated idioventricular rhythm | 38.60 | 27.04 | 7 | 3930 | 285 | 110585077 |
| Brachial plexopathy | 38.28 | 27.04 | 7 | 3930 | 299 | 110585063 |
| Atrioventricular block second degree | 36.69 | 27.04 | 13 | 3924 | 8168 | 110577194 |
| Anaphylactic reaction | 36.11 | 27.04 | 31 | 3906 | 114269 | 110471093 |
| Necrotising colitis | 35.75 | 27.04 | 9 | 3928 | 1756 | 110583606 |
| Atrioventricular block complete | 34.48 | 27.04 | 16 | 3921 | 20066 | 110565296 |
| Acute pulmonary oedema | 33.79 | 27.04 | 15 | 3922 | 16981 | 110568381 |
| Appendicitis perforated | 33.57 | 27.04 | 10 | 3927 | 3642 | 110581720 |
| Abdominal distension | 33.47 | 27.04 | 36 | 3901 | 175067 | 110410295 |
| Metabolic acidosis | 33.45 | 27.04 | 28 | 3909 | 99716 | 110485646 |
| Cholinergic syndrome | 33.08 | 27.04 | 8 | 3929 | 1324 | 110584038 |
| Bladder disorder | 32.79 | 27.04 | 13 | 3924 | 11124 | 110574238 |
| Pseudomonal sepsis | 31.76 | 27.04 | 12 | 3925 | 9034 | 110576328 |
| Dementia | 30.28 | 27.04 | 17 | 3920 | 31656 | 110553706 |
| Post procedural complication | 30.18 | 27.04 | 16 | 3921 | 26642 | 110558720 |
| Intestinal pseudo-obstruction | 30.03 | 27.04 | 9 | 3928 | 3347 | 110582015 |
| Non-cardiogenic pulmonary oedema | 29.92 | 27.04 | 8 | 3929 | 1976 | 110583386 |
| Angle closure glaucoma | 29.66 | 27.04 | 9 | 3928 | 3490 | 110581872 |
| Myopia | 28.85 | 27.04 | 8 | 3929 | 2263 | 110583099 |
| Respiratory failure | 27.45 | 27.04 | 36 | 3901 | 215296 | 110370066 |
None
| Source | Code | Description |
|---|---|---|
| ATC | N07AA01 | NERVOUS SYSTEM OTHER NERVOUS SYSTEM DRUGS PARASYMPATHOMIMETICS Anticholinesterases |
| ATC | N07AA51 | NERVOUS SYSTEM OTHER NERVOUS SYSTEM DRUGS PARASYMPATHOMIMETICS Anticholinesterases |
| ATC | S01EB06 | SENSORY ORGANS OPHTHALMOLOGICALS ANTIGLAUCOMA PREPARATIONS AND MIOTICS Parasympathomimetics |
| FDA MoA | N0000000177 | Cholinesterase Inhibitors |
| MeSH PA | D002800 | Cholinesterase Inhibitors |
| MeSH PA | D004791 | Enzyme Inhibitors |
| MeSH PA | D010277 | Parasympathomimetics |
| MeSH PA | D018377 | Neurotransmitter Agents |
| MeSH PA | D018678 | Cholinergic Agents |
| FDA EPC | N0000175723 | Cholinesterase Inhibitor |
| CHEBI has role | CHEBI:35480 | analgesic |
| CHEBI has role | CHEBI:35610 | antineoplastic agent |
| CHEBI has role | CHEBI:38462 | EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| CHEBI has role | CHEBI:39456 | antiglaucoma drug |
| CHEBI has role | CHEBI:55324 | gastrointestinal drug |
| CHEBI has role | CHEBI:74518 | anti-obesity agent |
| CHEBI has role | CHEBI:74530 | antidote to curare poisoning |
| CHEBI has role | CHEBI:231911 | renoprotective agent |
| CHEBI has role | CHEBI:37733 | EC 3.1.1.8 (cholinesterase) inhibitor |
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Myasthenia gravis | indication | 91637004 | DOID:437 |
| Reversal of neuromuscular blockade | indication | 241703000 | |
| Retention of urine | indication | 267064002 | |
| Urinary tract obstruction | contraindication | 7163005 | DOID:5200 |
| Peptic ulcer | contraindication | 13200003 | DOID:750 |
| Increased gastric tonus | contraindication | 18644006 | |
| Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
| Conduction disorder of the heart | contraindication | 44808001 | |
| Peritonitis | contraindication | 48661000 | |
| Sinus bradycardia | contraindication | 49710005 | |
| Coronary occlusion | contraindication | 63739005 | |
| Gastrointestinal obstruction | contraindication | 126765001 | |
| Seizure disorder | contraindication | 128613002 | |
| Asthma | contraindication | 195967001 | DOID:2841 |
| Macrocolon | contraindication | 367495003 | |
| Gastrointestinal hypomotility | contraindication | 421807004 | |
| Increased Bronchial Secretions | contraindication | ||
| Colonic Necrosis | contraindication |
| Species | Use | Relation |
|---|---|---|
| Cattle | Rumen atony | Indication |
| Cattle | Initiating peristalsis which causes evacuation of the bowel | Indication |
| Cattle | Emptying the urinary bladder | Indication |
| Cattle | Stimulating skeletal muscle contractions | Indication |
| Cattle | Antagonizes the effect of curare | Indication |
| Horses | Rumen atony | Indication |
| Horses | Initiating peristalsis which causes evacuation of the bowel | Indication |
| Horses | Emptying the urinary bladder | Indication |
| Horses | Stimulating skeletal muscle contractions | Indication |
| Horses | Antagonizes the effect of curare | Indication |
| Sheep | Rumen atony | Indication |
| Sheep | Initiating peristalsis which causes evacuation of the bowel | Indication |
| Sheep | Emptying the urinary bladder | Indication |
| Sheep | Stimulating skeletal muscle contractions | Indication |
| Sheep | Antagonizes the effect of curare | Indication |
| Swine | Rumen atony | Indication |
| Swine | Initiating peristalsis which causes evacuation of the bowel | Indication |
| Swine | Emptying the urinary bladder | Indication |
| Swine | Stimulating skeletal muscle contractions | Indication |
| Swine | Antagonizes the effect of curare | Indication |
| Product | Applicant | Ingredients |
|---|---|---|
| Stiglyn 1:500 | Intervet Inc. | 1 |
None
None
None
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Acetylcholinesterase | Enzyme | INHIBITOR | IC50 | 7.59 | WOMBAT-PK | CHEMBL | |||
| Cholinesterase | Enzyme | IC50 | 7.22 | CHEMBL | |||||
| Acetylcholinesterase | Enzyme | IC50 | 8.34 | CHEMBL | |||||
| Acetylcholinesterase | Enzyme | IC50 | 7.46 | CHEMBL | |||||
| Acetylcholinesterase | Enzyme | Ki | 6 | CHEMBL | |||||
| Cholinesterase | Enzyme | IC50 | 7.15 | CHEMBL |
| ID | Source |
|---|---|
| 4019856 | VUID |
| N0000147942 | NUI |
| D00995 | KEGG_DRUG |
| 51-60-5 | SECONDARY_CAS_RN |
| 4017784 | VANDF |
| 4017785 | VANDF |
| 4019856 | VANDF |
| C0027679 | UMLSCUI |
| CHEMBL278020 | ChEMBL_ID |
| DB01400 | DRUGBANK_ID |
| CHEMBL211471 | ChEMBL_ID |
| CHEMBL54126 | ChEMBL_ID |
| D009388 | MESH_DESCRIPTOR_UI |
| 4456 | PUBCHEM_CID |
| 8993 | IUPHAR_LIGAND_ID |
| 114-80-7 | SECONDARY_CAS_RN |
| 3982TWQ96G | UNII |
| 262500 | RXNORM |
| 3968 | MMSL |
| 5165 | MMSL |
| 5166 | MMSL |
| 72417 | MMSL |
| 9863 | MMSL |
| d00313 | MMSL |
| 001703 | NDDF |
| 001704 | NDDF |
| 001705 | NDDF |
| 373346001 | SNOMEDCT_US |
| 387294009 | SNOMEDCT_US |
| 80024007 | SNOMEDCT_US |
| 87151005 | SNOMEDCT_US |
| CHEBI:7514 | CHEBI |
| 401 | INN_ID |
| 3982TWQ96G | INXIGHT DRUGS |
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| NEOSTIGMINE METHYLSULFATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0548-9601 | INJECTION | 0.50 mg | INTRAVENOUS | ANDA | 16 sections |
| NEOSTIGMINE METHYLSULFATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0548-9602 | INJECTION | 1 mg | INTRAVENOUS | ANDA | 16 sections |
| Neostigmine Methylsulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-6149 | INJECTION | 1 mg | INTRAVENOUS | ANDA | 24 sections |
| Neostigmine Methylsulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-6150 | INJECTION | 0.50 mg | INTRAVENOUS | ANDA | 24 sections |
| Neostigmine Methylsulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-6264 | INJECTION | 0.50 mg | INTRAVENOUS | ANDA | 24 sections |
| Neostigmine Methylsulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-6265 | INJECTION | 1 mg | INTRAVENOUS | ANDA | 24 sections |
| Neostigmine Methylsulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-6277 | INJECTION | 1 mg | INTRAVENOUS | ANDA | 24 sections |
| NEOSTIGMINE METHYLSULFATE | Human Prescription Drug Label | 1 | 14445-413 | INJECTION | 0.50 mg | INTRAVENOUS | ANDA | 24 sections |
| NEOSTIGMINE METHYLSULFATE | Human Prescription Drug Label | 1 | 14445-414 | INJECTION | 1 mg | INTRAVENOUS | ANDA | 24 sections |
| Neostigmine Methylsulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-517 | INJECTION | 0.50 mg | INTRAVENOUS | ANDA | 23 sections |
| Neostigmine Methylsulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-518 | INJECTION | 1 mg | INTRAVENOUS | ANDA | 23 sections |
| Neostigmine Methylsulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 25021-610 | INJECTION, SOLUTION | 0.50 mg | INTRAVENOUS | ANDA | 28 sections |
| Neostigmine Methylsulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 25021-611 | INJECTION, SOLUTION | 1 mg | INTRAVENOUS | ANDA | 28 sections |
| neostigmine methylsulfate | Human Prescription Drug Label | 1 | 31722-994 | INJECTION | 0.50 mg | INTRAVENOUS | ANDA | 24 sections |
| neostigmine methylsulfate | Human Prescription Drug Label | 1 | 31722-995 | INJECTION | 1 mg | INTRAVENOUS | ANDA | 24 sections |
| NEOSTIGMINE METHYLSULFATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42023-188 | INJECTION | 0.50 mg | INTRAVENOUS | ANDA | 23 sections |
| NEOSTIGMINE METHYLSULFATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42023-189 | INJECTION | 1 mg | INTRAVENOUS | ANDA | 23 sections |
| PREVDUO | Human Prescription Drug Label | 2 | 42023-269 | INJECTION | 1 mg | INTRAVENOUS | NDA | 25 sections |
| Neostigmine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43598-528 | INJECTION | 0.50 mg | INTRAVENOUS | ANDA | 24 sections |
| Neostigmine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43598-529 | INJECTION | 1 mg | INTRAVENOUS | ANDA | 24 sections |
| Neostigmine Methylsulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43598-945 | INJECTION, SOLUTION | 1 mg | INTRAVENOUS | ANDA | 26 sections |
| NEOSTIGMINE METHYLSULFATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-4532 | INJECTION | 1 mg | INTRAVENOUS | ANDA | 17 sections |
| Neostigmine methylsulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-5197 | INJECTION | 0.50 mg | INTRAVENOUS | ANDA | 25 sections |
| NEOSTIGMINE METHYLSULFATE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51662-1557 | INJECTION | 1 mg | INTRAVENOUS | ANDA | 16 sections |
| Bloxiverz | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51754-1200 | INJECTION | 1 mg | INTRAVENOUS | NDA | 25 sections |
| Bloxiverz | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51754-1210 | INJECTION | 0.50 mg | INTRAVENOUS | NDA | 25 sections |
| Bloxiverz | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51754-1220 | INJECTION | 1 mg | INTRAVENOUS | NDA | 25 sections |
| Bloxiverz | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51754-1240 | INJECTION | 1 mg | INTRAVENOUS | NDA | 26 sections |
| Bloxiverz | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51754-1240 | INJECTION | 1 mg | INTRAVENOUS | NDA | 26 sections |
| NEOSTIGMINE METHYLSULFATE | Human Prescription Drug Label | 1 | 55150-348 | INJECTION | 0.50 mg | INTRAVENOUS | ANDA | 24 sections |