AI ASSISTANT
Ask DrugCentral
Explore drug properties, targets, and indications with answers grounded in DrugCentral.
Powered by DrugCentral + retrieval-augmented AIYour question
Ask in your own words. Each question is answered independently.
Explore sample questions
Select a question to fill the editor, then ask it or make it your own.
DrugCentral answer
Your answer will appear here. Open linked drug cards in a new tab to explore the source details.
About Ask DrugCentral
Ask DrugCentral helps you explore drug properties, biological targets, and indications using natural language. Sample questions offer starting points, and linked drug cards let you check the underlying records.
General architecture
- Ask a questionThe browser sends your question to the same-origin Django chat API.
- Retrieve and generateThe API forwards the question to the configured DrugCentral retrieval-augmented generation (RAG) service, which returns an AI-generated answer.
- Explore the answerThe app resolves cited drug-card names and displays the answer with links to drug records.
Using the assistant
Each request is independent; previous questions are not sent as conversation history. You can edit a sample before submitting, retry a failed request, or switch back to normal search. Drug links open in a new tab so your question and answer stay available.
Answers may contain mistakes or omit information. Verify details against DrugCentral records and original sources.
AI can make mistakes. Verify answers against the original sources before relying on them.
hydrocortisone aceponate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| corticosteroids, except prednisolone derivatives | 1389 | 74050-20-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| S (Water solubility) | 0.23 mg/mL | Bocci G, Oprea TI, Benet LZ |
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2B,AXL,BRAF,BTK,CAMK2D,CDK5,CDK9,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,MAPK7,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PRKDC,STK33,SYK,TEK | 23 | |||
| kinase-selectivity-class | AXL,GRK2,MAP2K6 | 3 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | D07AC16 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, PLAIN Corticosteroids, potent (group III) |
| FDA MoA | N0000175450 | Corticosteroid Hormone Receptor Agonists |
| FDA EPC | N0000175576 | Corticosteroid |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| CHEBI has role | CHEBI:35472 | anti-inflammatory drugs |
| CHEBI has role | CHEBI:49167 | anti-asthmatic drugs |
| CHEBI has role | CHEBI:50857 | anti-allergic drugs |
| CHEBI has role | CHEBI:75771 | Mus musculus metabolites |
| CHEBI has role | CHEBI:77746 | Homo sapiens metabolite |
| CHEBI has role | CHEBI:88188 | allergenic drug |
Related Drugs by ATC class:
D07AC Corticosteroids, potent (group III) 20 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Cats | Acute otitis externa | Indication |
| Cats | Chronic otitis externa | Indication |
| Cats | Ear canker | Indication |
| Cats | Inflammatory conditions of the external ear canal | Indication |
| Cats | Allergy | Indication |
| Cats | Infectious skin conditions | Indication |
| Cats | Traumatic skin conditions | Indication |
| Cats | Prevention of bacterial infections in superficial wounds | Indication |
| Cats | Prevention of bacterial infections in cuts | Indication |
| Cats | Prevention of bacterial infections in abrasions | Indication |
| Cats | Allergic dermatoses | Indication |
| Cats | Infections associated with minor burns and wounds | Indication |
| Cats | Nonspecific pruritus | Indication |
| Dogs | Acute otitis externa | Indication |
| Dogs | Chronic otitis externa | Indication |
| Dogs | Ear canker | Indication |
| Dogs | Inflammatory conditions of the external ear canal | Indication |
| Dogs | Allergy | Indication |
| Dogs | Infectious skin conditions | Indication |
| Dogs | Traumatic skin conditions | Indication |
| Dogs | Prevention of bacterial infections in superficial wounds | Indication |
| Dogs | Prevention of bacterial infections in cuts | Indication |
| Dogs | Prevention of bacterial infections in abrasions | Indication |
| Dogs | Allergic dermatoses | Indication |
| Dogs | Infections associated with minor burns and wounds | Indication |
| Dogs | Nonspecific pruritus | Indication |
| Horses | No Use Class Stated Or Implied | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Easotic | Virbac AH Inc. | 3 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D06876 | KEGG_DRUG |
| 4017941 | VANDF |
| C0082944 | UMLSCUI |
| CHEBI:135746 | CHEBI |
| CHEMBL2106309 | ChEMBL_ID |
| DB14538 | DRUGBANK_ID |
| C063919 | MESH_SUPPLEMENTAL_RECORD_UI |
| 5847 | INN_ID |
| 2340UP1L2G | UNII |
| 68921 | PUBCHEM_CID |
| DB00741 | DRUGBANK_ID |
| 41277 | RXNORM |
| 2500 | MMSL |
| 4837 | MMSL |
| d00254 | MMSL |
| 002147 | NDDF |
| 005250 | NDDF |
| 16602005 | SNOMEDCT_US |
| 396458002 | SNOMEDCT_US |
| 56423005 | SNOMEDCT_US |
| 708195009 | SNOMEDCT_US |
| C0020268 | UMLSCUI |
| 5754 | PUBCHEM_CID |
| 38 | INN_ID |
| D006854 | MESH_DESCRIPTOR_UI |
| CHEBI:17650 | CHEBI |
| 2340UP1L2G | INXIGHT DRUGS |
Pharmaceutical products:
None