Explore drug properties, targets, and indications with answers grounded in DrugCentral.
Powered by DrugCentral + retrieval-augmented AIAsk in your own words. Each question is answered independently.
Select a question to fill the editor, then ask it or make it your own.
Your answer will appear here. Open linked drug cards in a new tab to explore the source details.
Ask DrugCentral helps you explore drug properties, biological targets, and indications using natural language. Sample questions offer starting points, and linked drug cards let you check the underlying records.
Each request is independent; previous questions are not sent as conversation history. You can edit a sample before submitting, retry a failed request, or switch back to normal search. Drug links open in a new tab so your question and answer stay available.
Answers may contain mistakes or omit information. Verify details against DrugCentral records and original sources.
AI can make mistakes. Verify answers against the original sources before relying on them.
| Stem definition | Drug id | CAS RN |
|---|---|---|
| tumour necrosis factor | 5212 | 94948-59-1 |
| Molecule | Description |
|---|---|
|
Synonyms:
|
Tasonermin, is a copy of the human protein tumour necrosis factor alfa-1a (TNF-alfa). The exact way that TNF-alfa works against certain types of cancer is not fully understood, but it is thought that it can kill tumour cells directly, as well as destroy the blood vessels supplying tumours and stimulate the immune system to attack them. This leads to the tumour dying back and getting smaller, particularly when the medicine is combined with other cytotoxic (cell-killing) medicines and raised temperature.
|
| Dose | Unit | Route |
|---|---|---|
| 3.50 | mg | P |
None
None
| Date | Agency | Company | Orphan |
|---|---|---|---|
| April 13, 1999 | EMA | Boehringer Ingelheim International GmbH |
None
None
None
None
| Source | Code | Description |
|---|---|---|
| ATC | L03AX11 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS IMMUNOSTIMULANTS IMMUNOSTIMULANTS Other immunostimulants |
| CHEBI has role | CHEBI:35610 | antineoplastic agent |
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Sarcoma of soft tissue | indication | 424952003 |
None
None
None
None
None
None
| ID | Source |
|---|---|
| 23CA79S88F | UNII |
| C0937851 | UMLSCUI |
| CHEBI:752933 | CHEBI |
| CHEMBL2107891 | ChEMBL_ID |
| DB11626 | DRUGBANK_ID |
| D08562 | KEGG_DRUG |
| 7581 | INN_ID |
| 421147008 | SNOMEDCT_US |
| 421457001 | SNOMEDCT_US |
| 008935 | NDDF |
| 283746 | RXNORM |
None