ferrous gluconate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4491 299-29-6

Description:

MoleculeDescription

Synonyms:

  • sodium ferric gluconate complex
  • ferrous gluconate
  • iron gluconate
  • ferroglyconicum
  • glucoferron
iron important in this cpd; RN given refers to ferrous cpd
  • Molecular weight: 446.14
  • Formula: C12H22FeO14
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 265.04
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
0.20 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
Feb. 18, 1999 FDA SANOFI AVENTIS US

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Reversible airways obstruction 240.68 12.73 63 23378 1920 90603086
Vital capacity decreased 236.31 12.73 61 23380 1758 90603248
Sputum culture positive 223.37 12.73 61 23380 2192 90602814
Bronchial secretion retention 194.87 12.73 61 23380 3554 90601452
Presbyacusis 158.43 12.73 50 23391 2992 90602014
Pleural fibrosis 150.21 12.73 50 23391 3546 90601460
Eosinophil count increased 133.54 12.73 66 23375 13015 90591991
Pleural thickening 131.05 12.73 44 23397 3204 90601802
Deafness neurosensory 122.24 12.73 51 23390 6790 90598216
Blood magnesium increased 121.20 12.73 42 23399 3366 90601640
Multiple allergies 118.77 12.73 64 23377 15082 90589924
Upper-airway cough syndrome 116.03 12.73 63 23378 15072 90589934
Oesophageal spasm 114.06 12.73 40 23401 3321 90601685
Epigastric discomfort 110.79 12.73 49 23392 7519 90597487
Smear cervix abnormal 105.12 12.73 37 23404 3105 90601901
Oesophageal pain 103.78 12.73 40 23401 4334 90600672
Cyst 102.72 12.73 60 23381 16501 90588505
Obstructive airways disorder 101.12 12.73 70 23371 25799 90579207
Bone cyst 99.06 12.73 33 23408 2345 90602661
Allergic sinusitis 94.75 12.73 31 23410 2082 90602924
Pulmonary mass 85.56 12.73 66 23375 28706 90576300
Osteosclerosis 79.86 12.73 33 23408 4287 90600719
Hyperhidrosis 79.05 12.73 133 23308 136172 90468834
Abdominal pain 76.98 12.73 251 23190 395470 90209536
Hypotension 75.95 12.73 220 23221 325177 90279829
Blood pressure decreased 73.96 12.73 94 23347 74801 90530205
CFTR gene mutation 72.31 12.73 16 23425 233 90604773
Urticaria 71.59 12.73 210 23231 312524 90292482
Full blood count abnormal 69.77 12.73 65 23376 36532 90568474
Osteopenia 68.91 12.73 53 23388 22949 90582057
Lymphoedema 65.27 12.73 42 23399 13711 90591295
Flushing 63.21 12.73 95 23346 88396 90516610
Dyspnoea 56.48 12.73 405 23036 880550 89724456
Skin lesion 55.65 12.73 58 23383 37307 90567699
Discoloured vomit 55.52 12.73 18 23423 1174 90603832
Blood iron decreased 55.15 12.73 42 23399 17917 90587089
Deformity 54.90 12.73 36 23405 12134 90592872
Blood potassium increased 53.97 12.73 44 23397 20705 90584301
Sputum culture 52.27 12.73 13 23428 321 90604685
Respiratory tract infection 50.36 12.73 69 23372 59009 90545997
Anaphylactic reaction 50.18 12.73 85 23356 87439 90517567
Lip pruritus 49.28 12.73 17 23424 1343 90603663
Heart rate decreased 46.38 12.73 63 23378 53442 90551564
Pancreatitis relapsing 45.25 12.73 16 23425 1360 90603646
Chest discomfort 44.99 12.73 106 23335 138259 90466747
Myocardial infarction 44.50 12.73 90 23351 105882 90499124
Infusion related reaction 43.58 12.73 218 23223 416562 90188444
Toothache 43.36 12.73 40 23401 22190 90582816
Endodontic procedure 42.96 12.73 20 23421 3455 90601551
Occult blood 42.19 12.73 15 23426 1296 90603710
Skin fissures 41.68 12.73 38 23403 20771 90584235
Osteoarthritis 39.64 12.73 126 23315 195604 90409402
Localised infection 39.42 12.73 46 23395 33516 90571490
Tooth disorder 37.16 12.73 43 23398 31047 90573959
Internal haemorrhage 37.16 12.73 22 23419 6198 90598808
Type 2 diabetes mellitus 35.85 12.73 5 23436 203239 90401767
Systemic lupus erythematosus 35.70 12.73 25 23416 361871 90243135
Alopecia 35.10 12.73 46 23395 495025 90109981
Sleep apnoea syndrome 34.79 12.73 42 23399 31705 90573301
Dry eye 34.18 12.73 57 23384 57874 90547132
Glossodynia 33.39 12.73 21 23420 321758 90283248
Blood pressure fluctuation 32.85 12.73 53 23388 52360 90552646
Renal impairment 32.36 12.73 79 23362 105342 90499664
Vomiting 31.21 12.73 326 23115 787967 89817039
Blood uric acid increased 30.46 12.73 21 23420 7683 90597323
Pemphigus 30.40 12.73 24 23417 326840 90278166
Nausea 29.98 12.73 427 23014 1109889 89495117
Synovial disorder 29.66 12.73 15 23426 3103 90601903
Tinnitus 28.97 12.73 45 23396 43057 90561949
Sinusitis 28.52 12.73 28 23413 343060 90261946
Mite allergy 28.51 12.73 10 23431 830 90604176
Burning sensation 27.96 12.73 55 23386 63397 90541609
Therapeutic product effect incomplete 27.50 12.73 8 23433 193888 90411118
Completed suicide 26.97 12.73 3 23438 145055 90459951
Contusion 26.61 12.73 16 23425 251200 90353806
Syncope 26.47 12.73 85 23356 132578 90472428
Product use in unapproved indication 26.19 12.73 29 23412 336207 90268799
Wound 26.03 12.73 24 23417 302956 90302050
Hand deformity 26.03 12.73 23 23418 296339 90308667
Cough 25.48 12.73 173 23268 368789 90236217
Blood creatinine increased 24.99 12.73 70 23371 101316 90503690
Maternal exposure during pregnancy 24.95 12.73 34 23407 360029 90244977
Cystitis 24.89 12.73 54 23387 66664 90538342
Pallor 24.84 12.73 37 23404 34128 90570878
Agitation 24.68 12.73 54 23387 67044 90537962
Vitamin B12 decreased 24.66 12.73 16 23425 5294 90599712
Rheumatic fever 24.28 12.73 5 23436 153116 90451890
Paraesthesia 24.07 12.73 128 23313 250198 90354808
Skin discolouration 24.02 12.73 42 23399 44273 90560733
Post-traumatic stress disorder 23.27 12.73 17 23424 6811 90598195
Respiratory sinus arrhythmia magnitude 22.91 12.73 5 23436 68 90604938
Prostatic specific antigen abnormal 22.91 12.73 5 23436 68 90604938
Anal incontinence 22.05 12.73 24 23417 16206 90588800
Fluid retention 21.89 12.73 61 23380 88030 90516976
Skin depigmentation 21.81 12.73 9 23432 1164 90603842
Oedema peripheral 21.56 12.73 127 23314 257788 90347218
Bone hypertrophy 21.39 12.73 7 23434 470 90604536
Pericarditis 21.36 12.73 23 23418 270128 90334878
Abdominal pain upper 21.20 12.73 153 23288 332521 90272485
Loss of consciousness 21.20 12.73 82 23359 140156 90464850
Off label use 21.19 12.73 183 23258 1102069 89502937
Choluria 21.04 12.73 6 23435 253 90604753
Respiratory alkalosis 20.09 12.73 12 23429 3436 90601570
Contraindicated product administered 19.50 12.73 33 23408 320106 90284900
Hyperphosphataemia 19.27 12.73 12 23429 3699 90601307
Headache 18.98 12.73 138 23303 862608 89742398
Sleep disorder due to general medical condition, insomnia type 18.83 12.73 5 23436 128689 90476317
Anti-cyclic citrullinated peptide antibody positive 17.74 12.73 21 23420 236412 90368594
Dermatitis psoriasiform 17.41 12.73 10 23431 2662 90602344
Sleep disorder therapy 17.32 12.73 6 23435 480 90604526
Anaphylactoid reaction 17.24 12.73 12 23429 4456 90600550
Therapeutic reaction time decreased 16.93 12.73 11 23430 3647 90601359
Febrile neutropenia 16.88 12.73 10 23431 158339 90446667
Hypophosphataemia 16.84 12.73 20 23421 14834 90590172
Rheumatoid arthritis 15.74 12.73 153 23288 362461 90242545
Feeling abnormal 15.71 12.73 85 23356 167150 90437856
Hallucination, auditory 15.68 12.73 20 23421 15955 90589051
Pharyngeal haemorrhage 15.56 12.73 6 23435 650 90604356
Insomnia 15.56 12.73 40 23401 333434 90271572
Liver disorder 15.46 12.73 6 23435 121263 90483743
Analgesic therapy 15.42 12.73 6 23435 666 90604340
Peripheral swelling 15.42 12.73 169 23272 412937 90192069
Memory impairment 15.36 12.73 17 23424 197227 90407779
Cushingoid 15.23 12.73 16 23425 10379 90594627
Epidermolysis 15.11 12.73 6 23435 703 90604303
Product use issue 15.07 12.73 40 23401 329879 90275127
Synovitis 15.05 12.73 40 23401 329712 90275294
Swollen joint count increased 15.03 12.73 5 23436 111201 90493805
Intentional overdose 15.01 12.73 3 23438 93831 90511175
Antinuclear antibody positive 14.94 12.73 15 23426 9226 90595780
Iron deficiency anaemia 14.92 12.73 24 23417 23638 90581368
Rapid eye movements sleep abnormal 14.91 12.73 4 23437 134 90604872
Blood pressure systolic decreased 14.90 12.73 15 23426 9255 90595751
Helicobacter duodenal ulcer 14.88 12.73 3 23438 27 90604979
Stevens-Johnson syndrome 14.84 12.73 27 23414 29349 90575657
Neutropenia 14.81 12.73 22 23419 224882 90380124
Hallucination 14.76 12.73 44 23397 65915 90539091
Antacid therapy 14.75 12.73 6 23435 748 90604258
Appendicolith 14.70 12.73 6 23435 755 90604251
Drug therapy 14.35 12.73 6 23435 803 90604203
Anticoagulant therapy 14.29 12.73 6 23435 811 90604195
Haemoglobin abnormal 14.28 12.73 13 23428 7087 90597919
Road traffic accident 14.26 12.73 5 23436 107621 90497385
Duodenal ulcer perforation 14.23 12.73 22 23419 221266 90383740
Medication error 14.04 12.73 51 23390 84601 90520405
Pain in extremity 13.60 12.73 177 23264 450352 90154654
Nephrogenic systemic fibrosis 13.48 12.73 10 23431 4098 90600908
Colon cancer stage II 12.95 12.73 4 23437 223 90604783
Malaise 12.90 12.73 218 23223 585768 90019238
Dizziness 12.89 12.73 219 23222 589065 90015941
Cold sweat 12.84 12.73 17 23424 14064 90590942

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Appendicolith 546.66 22.33 193 13437 13263 42594442
Appendicitis 480.21 22.33 197 13433 20416 42587289
Cardiogenic shock 362.83 22.33 192 13438 35448 42572257
Stress 339.98 22.33 198 13432 44014 42563691
Ventricular fibrillation 317.10 22.33 166 13464 29957 42577748
Ascites 316.57 22.33 207 13423 56471 42551234
Abdominal distension 297.19 22.33 218 13412 71517 42536188
Blood phosphorus increased 295.90 22.33 121 13509 12404 42595301
Myasthenia gravis 216.89 22.33 105 13525 16032 42591673
Multiple organ dysfunction syndrome 216.10 22.33 206 13424 96829 42510876
Hyponatraemia 204.59 22.33 204 13426 101258 42506447
Hyperphosphataemia 194.23 22.33 91 13539 12913 42594792
Blood uric acid increased 190.53 22.33 95 13535 15452 42592253
Blood cholesterol increased 169.74 22.33 106 13524 26635 42581070
General physical health deterioration 168.86 22.33 224 13406 151022 42456683
Dry mouth 157.70 22.33 118 13512 39761 42567944
Hypophosphataemia 153.38 22.33 91 13539 20854 42586851
Incorrect route of product administration 150.86 22.33 95 13535 24210 42583495
Analgesic therapy 150.51 22.33 62 13568 6462 42601243
Bacterial infection 148.54 22.33 99 13531 27780 42579925
Sleep disorder therapy 147.20 22.33 62 13568 6832 42600873
Neuralgia 143.73 22.33 94 13536 25553 42582152
Abdominal pain 141.61 22.33 233 13397 190238 42417467
Constipation 137.77 22.33 211 13419 162080 42445625
Sepsis 129.90 22.33 230 13400 199104 42408601
Drug therapy 128.33 22.33 55 13575 6325 42601380
Drug intolerance 118.34 22.33 137 13493 80287 42527418
Drug hypersensitivity 101.29 22.33 141 13489 99248 42508457
Chronic obstructive pulmonary disease 83.68 22.33 102 13528 63012 42544693
Thrombosis 83.28 22.33 106 13524 68405 42539300
Swelling 83.20 22.33 95 13535 54790 42552915
Diabetes mellitus 82.75 22.33 99 13531 59988 42547717
Intentional product misuse 82.01 22.33 100 13530 61800 42545905
Sleep disorder 81.07 22.33 88 13542 48007 42559698
Aortic stenosis 80.11 22.33 44 13586 8701 42599004
Vomiting 78.07 22.33 236 13394 289487 42318218
Vitamin D deficiency 77.79 22.33 42 13588 8031 42599674
Antacid therapy 73.47 22.33 34 13596 4683 42603022
End stage renal disease 69.89 22.33 51 13579 16507 42591198
Activated partial thromboplastin time prolonged 69.44 22.33 50 13580 15853 42591852
Anticoagulant therapy 65.41 22.33 31 13599 4504 42603201
C-reactive protein decreased 64.59 22.33 25 13605 2211 42605494
Bacteroides infection 64.49 22.33 26 13604 2561 42605144
Ulcer 54.79 22.33 44 13586 16397 42591308
Somnolence 54.01 22.33 131 13499 140974 42466731
Nausea 49.07 22.33 253 13377 396546 42211159
Total lung capacity decreased 47.23 22.33 23 13607 3547 42604158
Toxicity to various agents 45.56 22.33 9 13621 229127 42378578
Troponin increased 45.21 22.33 42 13588 19020 42588685
Blood calcium increased 44.93 22.33 30 13600 8424 42599281
Hyperlipidaemia 44.57 22.33 44 13586 21472 42586233
Gout 43.22 22.33 49 13581 28006 42579699
Condition aggravated 43.02 22.33 181 13449 260573 42347132
Drug interaction 39.53 22.33 18 13612 266981 42340724
Gastrointestinal disorder 38.50 22.33 60 13570 46593 42561112
Dental caries 37.82 22.33 22 13608 4850 42602855
Pulmonary embolism 37.43 22.33 103 13527 119509 42488196
Bronchopulmonary aspergillosis allergic 36.32 22.33 21 13609 4577 42603128
Blood test abnormal 35.66 22.33 31 13599 12875 42594830
Congenital hiatus hernia 33.03 22.33 22 13608 6152 42601553
Lung opacity 31.71 22.33 21 13609 5816 42601889
Musculoskeletal stiffness 30.41 22.33 61 13569 57704 42550001
Blood pressure fluctuation 30.10 22.33 40 13590 26868 42580837
Haematochezia 27.58 22.33 59 13571 58377 42549328
Neutropenia 27.15 22.33 15 13615 199416 42408289
Anaemia 26.15 22.33 166 13464 280112 42327593
Aspiration 25.46 22.33 30 13600 17856 42589849
Colitis 24.29 22.33 49 13581 46523 42561182
Pyrexia 23.18 22.33 58 13572 393984 42213721

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Appendicolith 559.42 14.19 199 34834 14056 110540210
Appendicitis 441.84 14.19 204 34829 28260 110526006
Cardiogenic shock 296.01 14.19 199 34834 57139 110497127
Blood phosphorus increased 291.22 14.19 129 34904 16211 110538055
Ventricular fibrillation 287.08 14.19 173 34860 41140 110513126
Ascites 256.74 14.19 222 34811 92586 110461680
Stress 226.88 14.19 219 34814 105129 110449137
Blood uric acid increased 219.70 14.19 116 34917 21413 110532853
Myasthenia gravis 214.14 14.19 114 34919 21397 110532869
Vital capacity decreased 211.60 14.19 60 34973 2013 110552253
Reversible airways obstruction 209.21 14.19 62 34971 2437 110551829
Hyperphosphataemia 201.18 14.19 100 34933 16281 110537985
Abdominal pain 189.81 14.19 467 34566 512522 110041744
Abdominal distension 188.49 14.19 254 34779 174849 110379417
Sputum culture positive 174.43 14.19 60 34973 3829 110550437
Analgesic therapy 167.83 14.19 69 34964 7215 110547051
Sleep disorder therapy 166.14 14.19 69 34964 7402 110546864
Multiple organ dysfunction syndrome 164.67 14.19 221 34812 151489 110402777
Bronchial secretion retention 159.42 14.19 60 34973 4964 110549302
Hypophosphataemia 149.60 14.19 106 34927 33076 110521190
Drug therapy 144.34 14.19 62 34971 7229 110547037
Presbyacusis 136.25 14.19 46 34987 2773 110551493
Neuralgia 124.04 14.19 111 34922 48367 110505899
Bacterial infection 118.96 14.19 106 34927 45930 110508336
Pleural fibrosis 117.21 14.19 46 34987 4262 110550004
Oesophageal spasm 113.49 14.19 43 34990 3623 110550643
Hyponatraemia 112.80 14.19 227 34806 217426 110336840
Multiple allergies 110.91 14.19 61 34972 12202 110542064
Sepsis 107.31 14.19 285 34748 327061 110227205
Pleural thickening 105.70 14.19 40 34993 3359 110550907
Upper-airway cough syndrome 103.94 14.19 64 34969 15793 110538473
Smear cervix abnormal 103.10 14.19 37 34996 2675 110551591
Oesophageal pain 99.54 14.19 43 34990 5082 110549184
Blood magnesium increased 94.18 14.19 38 34995 3785 110550481
Incorrect route of product administration 91.29 14.19 107 34926 63954 110490312
Allergic sinusitis 89.78 14.19 30 35003 1751 110552515
Eosinophil count increased 89.70 14.19 65 34968 20993 110533273
Vomiting 87.94 14.19 540 34493 910135 109644131
Antacid therapy 87.22 14.19 40 34993 5444 110548822
Deafness neurosensory 84.66 14.19 47 34986 9572 110544694
Cyst 84.46 14.19 57 34976 16439 110537827
Aortic stenosis 83.80 14.19 52 34981 13007 110541259
Chronic obstructive pulmonary disease 83.60 14.19 135 34898 109023 110445243
Epigastric discomfort 81.96 14.19 45 34988 8970 110545296
End stage renal disease 79.66 14.19 61 34972 21412 110532854
Obstructive airways disorder 79.32 14.19 85 34948 46064 110508202
Bone cyst 79.18 14.19 33 35000 3570 110550696
Anticoagulant therapy 78.72 14.19 37 34996 5324 110548942
Osteosclerosis 75.17 14.19 34 34999 4481 110549785
Full blood count abnormal 73.91 14.19 90 34943 55962 110498304
Pulmonary mass 69.99 14.19 72 34961 37229 110517037
Diabetes mellitus 69.50 14.19 118 34915 99263 110455003
CFTR gene mutation 69.08 14.19 16 35017 233 110554033
Activated partial thromboplastin time prolonged 64.83 14.19 55 34978 22313 110531953
Nausea 64.01 14.19 634 34399 1235056 109319210
Lymphoedema 63.40 14.19 46 34987 14883 110539383
Bacteroides infection 61.68 14.19 26 35007 2893 110551373
Constipation 59.79 14.19 248 34785 357538 110196728
Osteopenia 59.08 14.19 52 34981 22157 110532109
Thrombosis 58.23 14.19 115 34918 108547 110445719
Completed suicide 58.20 14.19 5 35028 242376 110311890
Dry mouth 57.43 14.19 166 34867 199782 110354484
Blood pressure fluctuation 55.19 14.19 91 34942 74733 110479533
Toxicity to various agents 55.04 14.19 43 34990 480512 110073754
Deformity 51.76 14.19 35 34998 10125 110544141
General physical health deterioration 50.61 14.19 267 34766 425028 110129238
C-reactive protein decreased 48.73 14.19 22 35011 2887 110551379
Total lung capacity decreased 47.35 14.19 29 35004 7085 110547181
Gout 47.04 14.19 58 34975 36508 110517758
Sleep disorder 46.87 14.19 154 34879 198490 110355776
Lip pruritus 46.38 14.19 17 35016 1305 110552961
Sputum culture 45.62 14.19 12 35021 302 110553964
Dyspnoea 45.21 14.19 542 34491 1106330 109447936
Urticaria 44.88 14.19 210 34823 318647 110235619
Vitamin D deficiency 44.54 14.19 41 34992 18511 110535755
Troponin increased 42.86 14.19 50 34983 29716 110524550
Discoloured vomit 42.73 14.19 18 35015 1999 110552267
Flushing 42.47 14.19 99 34934 104637 110449629
Hyperhidrosis 42.23 14.19 143 34890 187155 110367111
Infusion related reaction 41.75 14.19 234 34799 380928 110173338
Intentional product misuse 41.73 14.19 114 34919 132790 110421476
Blood iron decreased 41.41 14.19 40 34993 19174 110535092
Endodontic procedure 41.05 14.19 20 35013 3116 110551150
Neutropenia 41.04 14.19 35 34998 374585 110179681
Pancreatitis relapsing 40.42 14.19 16 35017 1516 110552750
Blood cholesterol increased 39.84 14.19 139 34894 184646 110369620
Febrile neutropenia 37.98 14.19 27 35006 316740 110237526
Dry eye 37.35 14.19 65 34968 55728 110498538
Hyperlipidaemia 36.98 14.19 51 34982 35797 110518469
Toothache 36.30 14.19 41 34992 23534 110530732
Heart rate decreased 35.51 14.19 80 34953 82676 110471590
Congenital hiatus hernia 35.36 14.19 23 35010 6236 110548030
Anaphylactic reaction 34.85 14.19 97 34936 114203 110440063
Type 2 diabetes mellitus 34.61 14.19 7 35026 177225 110377041
Localised infection 33.98 14.19 54 34979 42994 110511272
Tooth disorder 33.52 14.19 44 34989 29465 110524801
Respiratory tract infection 32.72 14.19 71 34962 71546 110482720
Drug abuse 32.64 14.19 8 35025 177403 110376863
Ulcer 32.55 14.19 53 34980 43063 110511203
Blood calcium increased 32.36 14.19 34 34999 18006 110536260
Skin fissures 31.79 14.19 39 34994 24419 110529847
Internal haemorrhage 31.75 14.19 26 35007 10045 110544221
Drug intolerance 31.74 14.19 229 34804 406283 110147983
Lung opacity 30.43 14.19 27 35006 11625 110542641
Pyrexia 30.39 14.19 164 34869 898101 109656165
Sinusitis 29.79 14.19 30 35003 296658 110257608
Sleep apnoea syndrome 29.56 14.19 49 34984 40398 110513868
Skin lesion 29.30 14.19 56 34977 51575 110502691
Bronchopulmonary aspergillosis allergic 29.21 14.19 23 35010 8403 110545863
Blood pressure decreased 28.74 14.19 91 34942 115000 110439266
Intentional overdose 28.59 14.19 4 35029 132497 110421769
Osteoarthritis 28.45 14.19 124 34909 182499 110371767
Therapeutic product effect incomplete 28.26 14.19 18 35015 223787 110330479
Drug interaction 27.45 14.19 75 34958 500108 110054158
Blood potassium increased 26.64 14.19 42 34991 33207 110521059
Somnolence 25.82 14.19 172 34861 297277 110256989
Peripheral swelling 25.67 14.19 217 34816 403817 110150449
Blood test abnormal 25.60 14.19 38 34995 28516 110525750
Insomnia 25.56 14.19 47 34986 360543 110193723
Rheumatoid arthritis 24.66 14.19 171 34862 299442 110254824
Synovial disorder 24.58 14.19 14 35019 2993 110551273
Alopecia 24.58 14.19 49 34984 364704 110189562
White blood cell count decreased 24.42 14.19 22 35011 229368 110324898
Headache 24.17 14.19 172 34861 882205 109672061
Cystitis 24.16 14.19 60 34973 65976 110488290
Skin discolouration 23.99 14.19 50 34983 48996 110505270
Sputum discoloured 23.36 14.19 36 34997 27909 110526357
Blood creatinine increased 23.22 14.19 117 34916 182772 110371494
Systemic lupus erythematosus 23.02 14.19 28 35005 254310 110299956
Contusion 22.96 14.19 24 35009 233337 110320929
Dental caries 22.78 14.19 24 35009 12749 110541517
Thrombocytopenia 22.55 14.19 48 34985 348837 110205429
Interstitial lung disease 22.49 14.19 8 35025 139326 110414940
Maternal exposure during pregnancy 22.09 14.19 29 35004 254854 110299412
Respiratory sinus arrhythmia magnitude 21.91 14.19 5 35028 68 110554198
Vitamin B12 decreased 21.87 14.19 16 35017 5241 110549025
Rheumatic fever 21.64 14.19 6 35027 122573 110431693
Pancytopenia 21.26 14.19 21 35012 209592 110344674
Fluid retention 21.24 14.19 72 34961 94235 110460031
Disease progression 20.91 14.19 28 35005 244006 110310260
Post-traumatic stress disorder 20.73 14.19 17 35016 6579 110547687
Glossodynia 20.56 14.19 24 35009 221980 110332286
Chest discomfort 20.53 14.19 109 34924 173739 110380527
Coma 20.38 14.19 6 35027 117863 110436403
Wound 19.98 14.19 27 35006 234410 110319856
Musculoskeletal stiffness 19.76 14.19 154 34879 279668 110274598
Aspiration 19.69 14.19 35 34998 30498 110523768
Memory impairment 19.66 14.19 20 35013 196924 110357342
Lactic acidosis 19.56 14.19 3 35030 92808 110461458
Product use issue 19.22 14.19 44 34989 311651 110242615
Sleep disorder due to general medical condition, insomnia type 18.97 14.19 5 35028 105638 110448628
Hypotension 18.91 14.19 251 34782 523598 110030668
Leukopenia 18.74 14.19 12 35021 148779 110405487
Clostridium test positive 18.60 14.19 20 35013 10873 110543393
Pulmonary embolism 18.59 14.19 124 34909 214350 110339916
Hepatic function abnormal 18.57 14.19 3 35030 89292 110464974
Pericarditis 17.91 14.19 26 35007 219088 110335178
Iron deficiency anaemia 17.62 14.19 34 34999 31525 110522741
Road traffic accident 17.62 14.19 6 35027 107392 110446874
Drug-induced liver injury 17.58 14.19 8 35025 120059 110434207
Epilepsy 17.51 14.19 5 35028 100204 110454062
Therapeutic reaction time decreased 17.42 14.19 14 35019 5265 110549001
Acute kidney injury 17.30 14.19 124 34909 635306 109918960
Oedema peripheral 17.04 14.19 169 34864 328491 110225775
Nephrogenic systemic fibrosis 16.96 14.19 14 35019 5469 110548797
Withdrawal hypertension 16.95 14.19 6 35027 417 110553849
Bone hypertrophy 16.86 14.19 7 35026 750 110553516
Hand deformity 16.83 14.19 27 35006 218479 110335787
Neutrophil count decreased 16.29 14.19 9 35024 120932 110433334
Choluria 16.20 14.19 6 35027 474 110553792
Tinnitus 16.16 14.19 49 34984 60491 110493775
Drug hypersensitivity 16.14 14.19 217 34816 453873 110100393
Pemphigus 16.07 14.19 27 35006 214543 110339723
Breast cancer stage III 15.70 14.19 3 35030 79114 110475152
Swelling 15.61 14.19 175 34858 350866 110203400
Rales 15.50 14.19 28 35005 24711 110529555
Myocardial infarction 15.42 14.19 109 34924 191974 110362292
Cough 15.35 14.19 218 34815 461423 110092843
Synovitis 15.09 14.19 41 34992 274051 110280215
Respiratory symptom 15.02 14.19 21 35012 14924 110539342
Hepatitis 14.83 14.19 5 35028 90049 110464217
COVID-19 14.78 14.19 35 34998 245025 110309241

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC B03AA03 BLOOD AND BLOOD FORMING ORGANS
ANTIANEMIC PREPARATIONS
IRON PREPARATIONS
Iron bivalent, oral preparations
ATC B03AD05 BLOOD AND BLOOD FORMING ORGANS
ANTIANEMIC PREPARATIONS
IRON PREPARATIONS
Iron in combination with folic acid
FDA CS M0011718 Iron
MeSH PA D006397 Hematinics
MeSH PA D006401 Hematologic Agents
FDA EPC N0000177913 Parenteral Iron Replacement
CHEBI has role CHEBI:75835 anti-anaemic agent

Related Drugs by ATC class:

B03AA Iron bivalent, oral preparations 8 drugs
ferrous ascorbateferrous aspartateferrous carbonateferrous chlorideferrous fumarateferrous succinateferrous sulfateferrous tartrate
B03AD Iron in combination with folic acid 3 drugs
ferrous fumarateferrous sulfatefolic acid

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Anemia of prematurity indication 47100003 DOID:11243
Iron deficiency anemia indication 87522002
Peptic ulcer contraindication 13200003 DOID:750
Gastroenteritis contraindication 25374005 DOID:2326
Hemosiderosis contraindication 39011001 DOID:12119
Hemolytic anemia contraindication 61261009 DOID:583
Ulcerative colitis contraindication 64766004 DOID:8577
Diverticular disease contraindication 397881000
Hemochromatosis contraindication 399187006 DOID:2352
Repeated Blood Transfusions contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D02394 KEGG_DRUG
4024159 VUID
N0000148626 NUI
6047-12-7 SECONDARY_CAS_RN
34089-81-1 SECONDARY_CAS_RN
4017678 VANDF
4019180 VANDF
4021178 VANDF
4024159 VANDF
CHEBI:31608 CHEBI
CHEMBL3833303 ChEMBL_ID
CHEMBL1201494 ChEMBL_ID
C011819 MESH_SUPPLEMENTAL_RECORD_UI
DB14488 DRUGBANK_ID
U1B11I423Z UNII
DB09517 DRUGBANK_ID
24942 RXNORM
189358 MMSL
4724 MMSL
5409 MMSL
7975 MMSL
d03822 MMSL
d04387 MMSL
000834 NDDF
007777 NDDF
116130008 SNOMEDCT_US
26736008 SNOMEDCT_US
387147005 SNOMEDCT_US
786421005 SNOMEDCT_US
C0060277 UMLSCUI
23616740 PUBCHEM_CID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Ferrlecit HUMAN PRESCRIPTION DRUG LABEL 1 0024-2792 INJECTION 12.50 mg INTRAVENOUS NDA 25 sections
Ferrlecit HUMAN PRESCRIPTION DRUG LABEL 1 0024-2794 INJECTION 12.50 mg INTRAVENOUS NDA 26 sections
Sodium Ferric Gluconate Complex in Sucrose HUMAN PRESCRIPTION DRUG LABEL 1 0143-9298 INJECTION 12.50 mg INTRAVENOUS ANDA 24 sections
Sodium Ferric Gluconate Complex in Sucrose HUMAN PRESCRIPTION DRUG LABEL 1 0143-9570 INJECTION 12.50 mg INTRAVENOUS ANDA 24 sections
CitraNatal 90 DHA HUMAN PRESCRIPTION DRUG LABEL 16 0178-0821 TABLET 5 mg ORAL unapproved drug other 11 sections
BioFerr 90 HUMAN PRESCRIPTION DRUG LABEL 6 44523-732 TABLET, FILM COATED 13.20 mg ORAL Unapproved drug other 20 sections
Embriva HUMAN PRESCRIPTION DRUG LABEL 9 85477-322 TABLET 13 mg ORAL unapproved drug other 8 sections
Gestyra HUMAN PRESCRIPTION DRUG LABEL 9 85477-922 TABLET 13 mg ORAL unapproved drug other 8 sections