clofezone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
anti-inflammatory analgesics, phenylbutazone derivatives 4335 17449-96-6

Description:

MoleculeDescription

Synonyms:

  • clofezone
  • clofezon
  • percluson
  • perclusone
  • clofexamide-phenylbutazone
was MH 1975-92 (see under PHENYLBUTAZONE 1975-90); use PHENYLBUTAZONE to search CLOFEZONE 1975-92; an analgesic & antipyretic with anti-inflammatory properties used in treatment of rheumatism
  • Molecular weight: 593.17
  • Formula: C33H41ClN4O4
  • CLOGP: 5.96
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
0.60 g O
0.60 g R

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC M01AA05 MUSCULO-SKELETAL SYSTEM
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Butylpyrazolidines
ATC M02AA03 MUSCULO-SKELETAL SYSTEM
TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
Antiinflammatory preparations, non-steroids for topical use
CHEBI has role CHEBI:49200 proton pump inhibitors
CHEBI has role CHEBI:49201 anti-ulcer drugs

Related Drugs by ATC class:

M01AA Butylpyrazolidines 4 drugs
kebuzonemofebutazoneoxyphenbutazonephenylbutazone
M02AA Antiinflammatory preparations, non-steroids for topical use 28 drugs
aceclofenacbendazacbenzydaminebufexamacdexketoprofendiclofenacesflurbiprofenetofenamatefelbinacfentiazacfeprazoneflurbiprofen show all 28 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07263 KEGG_DRUG
60104-29-2 SECONDARY_CAS_RN
C0650237 UMLSCUI
CHEBI:8768 CHEBI
CHEMBL6067984 ChEMBL_ID
DB01129 DRUGBANK_ID
C073326 MESH_SUPPLEMENTAL_RECORD_UI
2274 INN_ID
TPT3MH65LD UNII
6433695 PUBCHEM_CID
183877 RXNORM
005303 NDDF

Pharmaceutical products:

None