carbocisteine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
mucolytics 4160 638-23-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • carbocisteine
  • bronchokod
  • carbocit
  • carbocysteine
  • chilvax
  • L-(Carboxymethyl)cysteine
  • lisil
  • lisomucil
  • loviscol
  • muciclar
  • mucocis
  • mucodyne
  • mucofan
  • mucolase
  • mucolex
  • mucopront
  • mucosol
  • mucotab
  • mukinyl
  • PectDrill
  • pectox
  • pulmoclase
  • reomucil
  • rhinathiol
  • rhinatiol
  • thiodril
  • transbronchin
  • carbocisteine sodium
A compound formed when iodoacetic acid reacts with sulfhydryl groups in proteins. It has been used as an anti-infective nasal spray with mucolytic and expectorant action.
  • Molecular weight: 179.19
  • Formula: C5H9NO4S
  • CLOGP: -2.61
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 3
  • TPSA: 100.62
  • ALOGS: -0.92
  • ROTB: 5

Drug dosage:

DoseUnitRoute
1.50 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,ACVRL1,AKT2,AKT3,ALK,AURKA,AXL,BMX,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT1,FLT3,GRK2,GRK3,GSK3B,IGF1R,IKBKB,ITK,JAK1,JAK2,JAK3,KDR,MAP2K6,MAP3K14,MAP3K21,MAP3K7,MAP4K1,MAPK10,MAPK12,MAPK7,MAPK9,MAPKAPK2,MTOR,NTRK1,NTRK2,PDK1,PDK2,PDK4,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ZAP70 67
kinase-selectivity-class ACVR2B,AXL,BRAF,CDK9,DYRK1B,EIF2AK3,EPHB4,GRK2,MAP2K6,MAP3K14,MAPK7,PIK3CB,PIK3CD,PIK3CG,PRKDC,STK33,TEK,TGFBR1 18
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Pulmonary pain 192.83 18.26 54 9980 5060 90613353
Amyloid arthropathy 191.34 18.26 43 9991 1637 90616776
Pneumonia bacterial 95.13 18.26 40 9994 12750 90605663
Upper respiratory tract inflammation 90.71 18.26 26 10008 2646 90615767
Interstitial lung disease 84.46 18.26 69 9965 76336 90542077
Hepatic function abnormal 80.78 18.26 55 9979 46233 90572180
Drug ineffective 76.76 18.26 29 10005 1384269 89234144
Drug eruption 76.26 18.26 48 9986 35359 90583054
Lower respiratory tract infection 61.44 18.26 104 9930 250555 90367858
Platelet count decreased 55.48 18.26 72 9962 136897 90481516
Pain 54.88 18.26 21 10013 996320 89622093
Haemoptysis 54.37 18.26 38 9996 33282 90585131
Adrenal suppression 53.75 18.26 14 10020 995 90617418
Cardiac failure 49.81 18.26 61 9973 109435 90508978
Pneumonia aspiration 49.53 18.26 39 9995 40901 90577512
Hyponatraemia 46.16 18.26 65 9969 133473 90484940
Lip swelling 45.03 18.26 36 9998 38574 90579839
Drug abuse 44.29 18.26 50 9984 82297 90536116
Diarrhoea 42.87 18.26 211 9823 938979 89679434
Intentional product misuse 42.50 18.26 51 9983 89553 90528860
Fatigue 40.55 18.26 41 9993 1153982 89464431
Adjusted calcium decreased 38.10 18.26 8 10026 220 90618193
Upper gastrointestinal haemorrhage 37.01 18.26 26 10008 22950 90595463
Pneumonia 37.01 18.26 154 9880 637905 89980508
Drug interaction 36.78 18.26 89 9945 276364 90342049
Myopathy 35.98 18.26 21 10013 13497 90604916
Product administration error 35.96 18.26 27 10007 26396 90592017
Infective exacerbation of chronic obstructive airways disease 35.40 18.26 11 10023 1475 90616938
Infusion related reaction 35.04 18.26 3 10031 416777 90201636
Asteatosis 34.36 18.26 6 10028 59 90618354
Palpitations 33.80 18.26 57 9977 136671 90481742
Stevens-Johnson syndrome 33.43 18.26 27 10007 29349 90589064
Blood prolactin increased 32.58 18.26 13 10021 3624 90614789
Infective exacerbation of bronchiectasis 32.27 18.26 8 10026 466 90617947
Pyrexia 31.19 18.26 150 9884 660335 89958078
Erythema multiforme 29.92 18.26 18 10016 12228 90606185
Oesophageal irritation 29.60 18.26 7 10027 334 90618079
Sputum retention 29.57 18.26 8 10026 658 90617755
Knee arthroplasty 29.49 18.26 41 9993 83141 90535272
Gastroenteritis 29.37 18.26 25 10009 29204 90589209
Overdose 27.98 18.26 57 9977 157652 90460761
Obesity 27.43 18.26 45 9989 105462 90512951
Systemic lupus erythematosus 26.92 18.26 4 10030 361892 90256521
Glossodynia 25.26 18.26 3 10031 321776 90296637
Anaemia 25.16 18.26 91 9943 352711 90265702
Tendonitis 25.07 18.26 20 10014 21352 90597061
Hypozincaemia 24.80 18.26 4 10030 23 90618390
Enterocolitis 24.55 18.26 15 10019 10475 90607938
Pneumomediastinum 24.43 18.26 9 10025 2022 90616391
Joint swelling 23.89 18.26 13 10021 503287 90115126
Drug dependence 23.36 18.26 22 10012 29305 90589108
Bronchitis 23.34 18.26 52 9982 152875 90465538
Galactorrhoea 23.15 18.26 11 10023 4661 90613752
Asthma 23.13 18.26 69 9965 242091 90376322
Drug-induced liver injury 22.77 18.26 38 9996 90280 90528133
Hypoglycaemia 22.65 18.26 33 10001 69815 90548598
Pharyngitis 22.52 18.26 19 10015 21928 90596485
Urine output decreased 22.03 18.26 15 10019 12588 90605825
Drug hypersensitivity 21.97 18.26 12 10022 463597 90154816
Reversible cerebral vasoconstriction syndrome 21.31 18.26 10 10024 4120 90614293
Sputum increased 21.16 18.26 9 10025 2948 90615465
Maternal exposure during pregnancy 20.74 18.26 7 10027 360056 90258357
Contraindicated product administered 20.70 18.26 5 10029 320134 90298279
Loss of consciousness 19.53 18.26 46 9988 140192 90478221
Enteritis infectious 19.40 18.26 8 10026 2427 90615986
Rheumatoid arthritis 19.29 18.26 8 10026 362606 90255807
Hypoalbuminaemia 18.91 18.26 15 10019 15882 90602531
Depression 18.84 18.26 5 10029 300596 90317817
Atrial fibrillation 18.80 18.26 44 9990 133567 90484846
Pneumothorax 18.46 18.26 16 10018 19151 90599262
Eosinophilic pneumonia 18.39 18.26 8 10026 2765 90615648

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Interstitial lung disease 175.39 16.07 151 10685 78311 42532188
Pneumonia aspiration 129.66 16.07 105 10731 49973 42560526
Hepatic function abnormal 116.64 16.07 100 10736 51467 42559032
Lower respiratory tract infection 93.33 16.07 80 10756 41126 42569373
Pneumonia 90.48 16.07 273 10563 421876 42188623
Radiation inflammation 88.83 16.07 25 10811 1023 42609476
Pulmonary pain 78.73 16.07 25 10811 1553 42608946
Idiopathic pulmonary fibrosis 71.78 16.07 31 10805 4573 42605926
Pneumonia bacterial 60.92 16.07 42 10794 15650 42594849
Drug ineffective 58.70 16.07 45 10791 630152 41980347
Lung neoplasm malignant 51.30 16.07 41 10795 19106 42591393
Fatigue 50.40 16.07 24 10812 435617 42174882
Upper respiratory tract inflammation 44.07 16.07 17 10819 1879 42608620
Genital pain 39.61 16.07 13 10823 897 42609602
Genital ulceration 35.87 16.07 12 10824 879 42609620
Schizophrenia 33.51 16.07 25 10811 10525 42599974
Drug eruption 33.42 16.07 35 10801 23040 42587459
Liver disorder 30.98 16.07 44 10792 39600 42570899
Malignant neoplasm progression 29.79 16.07 77 10759 108323 42502176
Prostate tenderness 29.77 16.07 6 10830 55 42610444
Dyspnoea 29.08 16.07 202 10634 442419 42168080
Pneumothorax 27.66 16.07 32 10804 23511 42586988
Paraneoplastic rash 27.18 16.07 6 10830 88 42610411
Hyponatraemia 26.78 16.07 71 10765 101391 42509108
Drug-induced liver injury 26.32 16.07 40 10796 38233 42572266
Food poisoning 25.90 16.07 13 10823 2693 42607806
Neutrophil count decreased 25.08 16.07 52 10784 63363 42547136
Gastrointestinal pain 25.02 16.07 15 10821 4400 42606099
Hypophagia 24.20 16.07 32 10804 26924 42583575
Antibody test abnormal 23.89 16.07 7 10829 331 42610168
Clumsiness 23.87 16.07 11 10825 1889 42608610
Contusion 23.56 16.07 40 10796 41945 42568554
Malaise 23.20 16.07 111 10725 212045 42398454
Infective exacerbation of chronic obstructive airways disease 23.16 16.07 11 10825 2022 42608477
Sputum retention 22.75 16.07 8 10828 681 42609818
Knee arthroplasty 21.82 16.07 18 10818 8763 42601736
Hallucination 21.39 16.07 46 10790 57461 42553038
Somnambulism 20.39 16.07 12 10824 3403 42607096
Inappropriate antidiuretic hormone secretion 20.30 16.07 23 10813 16518 42593981
Nephrotic syndrome 19.86 16.07 17 10819 8701 42601798
Neuropsychiatric syndrome 19.83 16.07 5 10831 133 42610366
Radiation pneumonitis 19.36 16.07 11 10825 2922 42607577
Irritable bowel syndrome 19.28 16.07 13 10823 4668 42605831
Mouth swelling 19.20 16.07 10 10826 2236 42608263
Toxicity to various agents 19.19 16.07 18 10818 229118 42381381
Gastric mucosal lesion 18.79 16.07 7 10829 703 42609796
Hyperuricaemia 18.72 16.07 17 10819 9407 42601092
Inflammation 18.66 16.07 32 10804 33815 42576684
Sputum increased 18.58 16.07 11 10825 3152 42607347
Duodenal ulcer perforation 18.39 16.07 9 10827 1767 42608732
Cerebral infarction 17.89 16.07 30 10806 31139 42579360
Bronchitis 17.83 16.07 38 10798 47163 42563336
Eye infection 17.69 16.07 12 10824 4349 42606150
Injection site induration 17.59 16.07 11 10825 3476 42607023
Concomitant disease aggravated 17.41 16.07 14 10822 6572 42603927
Fulminant type 1 diabetes mellitus 17.40 16.07 8 10828 1366 42609133
Clonic convulsion 17.37 16.07 7 10829 868 42609631
Lipid metabolism disorder 17.29 16.07 6 10830 491 42610008
Nightmare 16.99 16.07 26 10810 24986 42585513
Orthostatic hypotension 16.98 16.07 29 10807 30541 42579958
Stevens-Johnson syndrome 16.42 16.07 24 10812 22154 42588345
Cardiac failure 16.38 16.07 62 10774 106794 42503705
Platelet count decreased 16.22 16.07 74 10762 138507 42471992
Anxiety 16.19 16.07 5 10831 118555 42491944
Arthralgia 16.17 16.07 17 10819 205221 42405278

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Pulmonary pain 253.23 15.41 79 20981 6214 110562025
Interstitial lung disease 251.76 15.41 210 20850 139124 110429115
Hepatic function abnormal 200.58 15.41 153 20907 89142 110479097
Pneumonia aspiration 184.23 15.41 140 20920 81093 110487146
Amyloid arthropathy 168.10 15.41 43 21017 1637 110566602
Pneumonia bacterial 146.93 15.41 80 20980 26181 110542058
Pneumonia 125.82 15.41 409 20651 876305 109691934
Upper respiratory tract inflammation 123.56 15.41 42 21018 4329 110563910
Drug ineffective 117.10 15.41 73 20987 1520467 109047772
Drug eruption 101.20 15.41 83 20977 53576 110514663
Radiation inflammation 95.98 15.41 25 21035 1023 110567216
Fatigue 88.55 15.41 62 20998 1215896 109352343
Lower respiratory tract infection 86.27 15.41 161 20899 242945 110325294
Pain 73.07 15.41 46 21014 954909 109613330
Platelet count decreased 72.43 15.41 145 20915 230298 110337941
Idiopathic pulmonary fibrosis 71.02 15.41 29 21031 4975 110563264
Hyponatraemia 69.66 15.41 138 20922 217515 110350724
Cardiac failure 62.50 15.41 121 20939 187505 110380734
Haemoptysis 60.06 15.41 71 20989 71283 110496956
Infective exacerbation of chronic obstructive airways disease 54.02 15.41 21 21039 3169 110565070
Pneumothorax 49.24 15.41 46 21014 35239 110533000
Stevens-Johnson syndrome 48.58 15.41 52 21008 46849 110521390
Lip swelling 46.98 15.41 53 21007 50614 110517625
Upper gastrointestinal haemorrhage 45.76 15.41 52 21008 50044 110518195
Knee arthroplasty 45.60 15.41 59 21001 64889 110503350
Neutrophil count decreased 43.98 15.41 81 20979 120860 110447379
Malignant neoplasm progression 43.48 15.41 100 20960 174467 110393772
Dyspnoea 43.47 15.41 359 20701 1106513 109461726
Lung neoplasm malignant 43.20 15.41 42 21018 33800 110534439
Sputum retention 42.13 15.41 14 21046 1345 110566894
Drug hypersensitivity 41.94 15.41 17 21043 454073 110114166
Infusion related reaction 40.92 15.41 11 21049 381151 110187088
Drug-induced liver injury 40.65 15.41 78 20982 119989 110448250
Erythema multiforme 40.53 15.41 33 21027 21064 110547175
Cerebral infarction 39.41 15.41 49 21011 51789 110516450
Sputum increased 39.20 15.41 20 21040 5731 110562508
Genital pain 37.80 15.41 13 21047 1387 110566852
Pyrexia 37.74 15.41 296 20764 897969 109670270
Diarrhoea 37.70 15.41 356 20704 1139149 109429090
Prostate tenderness 36.76 15.41 7 21053 64 110568175
Tendonitis 36.39 15.41 34 21026 26049 110542190
Hypozincaemia 35.59 15.41 7 21053 77 110568162
Adrenal suppression 35.36 15.41 13 21047 1683 110566556
Completed suicide 35.00 15.41 3 21057 242378 110325861
Chronic obstructive pulmonary disease 34.63 15.41 69 20991 109089 110459150
Asthenia 34.11 15.41 49 21011 688950 109879289
Nephrotic syndrome 33.91 15.41 25 21035 13806 110554433
Enterocolitis 32.99 15.41 28 21032 18921 110549318
Intentional product misuse 32.94 15.41 76 20984 132828 110435411
Toxicity to various agents 32.90 15.41 26 21034 480529 110087710
Adjusted calcium decreased 32.82 15.41 8 21052 249 110567990
Bronchitis 32.73 15.41 84 20976 156948 110411291
Febrile convulsion 32.69 15.41 11 21049 1099 110567140
Weight increased 32.30 15.41 20 21040 419624 110148615
Systemic lupus erythematosus 32.13 15.41 5 21055 254333 110313906
Glossodynia 31.38 15.41 3 21057 222001 110346238
Wound 31.03 15.41 4 21056 234433 110333806
Pericarditis 30.87 15.41 3 21057 219111 110349128
Hyperuricaemia 30.62 15.41 24 21036 14507 110553732
Discomfort 30.09 15.41 3 21057 214704 110353535
Pneumomediastinum 30.00 15.41 16 21044 5020 110563219
Genital ulceration 29.93 15.41 12 21048 1963 110566276
Paraneoplastic rash 28.84 15.41 6 21054 89 110568150
Orthostatic hypotension 28.79 15.41 48 21012 66201 110502038
Therapeutic product effect decreased 28.28 15.41 6 21054 244310 110323929
Maternal exposure during pregnancy 28.02 15.41 7 21053 254876 110313363
Treatment failure 27.92 15.41 9 21051 277225 110291014
Respiratory failure 27.60 15.41 97 20963 215235 110353004
Lymphangiosis carcinomatosa 27.29 15.41 12 21048 2470 110565769
Hypophagia 26.81 15.41 41 21019 52585 110515654
Arthralgia 26.75 15.41 69 20991 779563 109788676
Altered state of consciousness 26.72 15.41 43 21017 57583 110510656
Food poisoning 26.49 15.41 16 21044 6356 110561883
Rheumatoid arthritis 26.40 15.41 12 21048 299601 110268638
Constipation 26.24 15.41 136 20924 357650 110210589
Radiation pneumonitis 25.86 15.41 14 21046 4522 110563717
Schizophrenia 25.84 15.41 26 21034 21800 110546439
Disseminated intravascular coagulation 25.14 15.41 35 21025 41251 110526988
Abnormal behaviour 25.14 15.41 34 21026 39005 110529234
Hallucination 25.12 15.41 58 21002 101374 110466865
Malaise 24.73 15.41 215 20845 671604 109896635
Fulminant type 1 diabetes mellitus 24.61 15.41 11 21049 2352 110565887
Pharyngitis 24.54 15.41 27 21033 25071 110543168
Weight decreased 24.43 15.41 32 21028 468025 110100214
Renal impairment 24.24 15.41 85 20975 188360 110379879
Infective exacerbation of bronchiectasis 23.13 15.41 8 21052 868 110567371
Rash 22.97 15.41 248 20812 820716 109747523
Asthma 22.58 15.41 101 20959 250190 110318049
Blood cholesterol increased 22.52 15.41 4 21056 184781 110383458
Asteatosis 22.41 15.41 6 21054 273 110567966
Enteritis infectious 22.19 15.41 12 21048 3870 110564369
Clonic convulsion 21.89 15.41 9 21051 1571 110566668
Oesophageal irritation 21.89 15.41 6 21054 299 110567940
Laryngopharyngitis 21.88 15.41 5 21055 117 110568122
Folliculitis 21.85 15.41 3 21057 167650 110400589
Mobility decreased 21.72 15.41 9 21051 237413 110330826
Sinusitis 21.65 15.41 15 21045 296673 110271566
Palpitations 21.51 15.41 73 20987 159139 110409100
COVID-19 21.44 15.41 98 20962 244962 110323277
Joint swelling 21.39 15.41 32 21028 442813 110125426
Fixed eruption 21.22 15.41 12 21048 4220 110564019
Liver disorder 20.80 15.41 67 20993 142176 110426063
Memory impairment 20.53 15.41 6 21054 196938 110371301
Gastric mucosal lesion 20.43 15.41 8 21052 1231 110567008
Drug reaction with eosinophilia and systemic symptoms 20.39 15.41 47 21013 82048 110486191
Blood prolactin increased 20.19 15.41 12 21048 4630 110563609
Paraesthesia 20.15 15.41 14 21046 276507 110291732
Osteoarthritis 20.10 15.41 5 21055 182618 110385621
Melaena 20.07 15.41 42 21018 68715 110499524
Hepatic enzyme increased 19.96 15.41 19 21041 320873 110247366
Immunosuppressant drug level increased 19.75 15.41 17 21043 11707 110556532
Clumsiness 19.72 15.41 11 21049 3769 110564470
Exposure during pregnancy 19.60 15.41 4 21056 167420 110400819
Gastroenteritis 19.44 15.41 30 21030 38770 110529469
General physical health deterioration 19.33 15.41 32 21028 425263 110142976
Type 2 diabetes mellitus 19.22 15.41 5 21055 177227 110391012
Adrenocorticotropic hormone deficiency 19.10 15.41 9 21051 2173 110566066
Alopecia 18.96 15.41 25 21035 364728 110203511
Neuropsychiatric syndrome 18.89 15.41 5 21055 218 110568021
Asphyxia 18.81 15.41 18 21042 14197 110554042
Diabetes mellitus 18.51 15.41 51 21009 99330 110468909
Depression 18.36 15.41 20 21040 317315 110250924
Product use in unapproved indication 18.24 15.41 36 21024 447341 110120898
Antibody test abnormal 18.04 15.41 7 21053 1051 110567188
Drug abuse 17.84 15.41 74 20986 177337 110390902
Physical deconditioning 17.65 15.41 10 21050 3527 110564712
Lipid metabolism disorder 17.37 15.41 6 21054 648 110567591
Mouth swelling 17.37 15.41 13 21047 7341 110560898
Overdose 17.22 15.41 89 20971 233705 110334534
Lung adenocarcinoma stage II 17.17 15.41 3 21057 16 110568223
Duodenal perforation 17.06 15.41 9 21051 2761 110565478
Inappropriate antidiuretic hormone secretion 16.71 15.41 26 21034 33825 110534414
Concomitant disease aggravated 16.69 15.41 18 21042 16346 110551893
Iron deficiency anaemia 16.66 15.41 25 21035 31534 110536705
Zinc deficiency 16.53 15.41 5 21055 354 110567885
Non-small cell lung cancer 16.49 15.41 13 21047 7922 110560317
Oculomucocutaneous syndrome 16.49 15.41 5 21055 357 110567882
Hyperkalaemia 16.39 15.41 60 21000 135736 110432503
Decreased appetite 16.30 15.41 150 20910 475696 110092543
Contraindicated product administered 16.27 15.41 14 21046 248253 110319986
Pleural effusion 16.23 15.41 72 20988 177637 110390602
Injection site induration 16.19 15.41 15 21045 11368 110556871
Galactorrhoea 16.16 15.41 10 21050 4145 110564094
Urine flow decreased 16.11 15.41 7 21053 1399 110566840
Productive cough 15.95 15.41 53 21007 114252 110453987
Sleep disorder 15.93 15.41 9 21051 198635 110369604
Injection site pain 15.86 15.41 7 21053 177915 110390324
Intentional overdose 15.86 15.41 3 21057 132498 110435741
Musculoskeletal stiffness 15.78 15.41 18 21042 279804 110288435
Gastrointestinal pain 15.66 15.41 15 21045 11845 110556394
Anaemia 15.60 15.41 166 20894 546920 110021319
Cardiac failure acute 15.55 15.41 21 21039 24057 110544182
Myositis 15.50 15.41 24 21036 31092 110537147
Urine output decreased 15.45 15.41 19 21041 19857 110548382

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R05CB03 RESPIRATORY SYSTEM
COUGH AND COLD PREPARATIONS
EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS
Mucolytics
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000891 Anti-Infective Agents, Local
MeSH PA D005100 Expectorants
MeSH PA D019141 Respiratory System Agents
CHEBI has role CHEBI:77034 mucolytics

Related Drugs by ATC class:

R05CB Mucolytics 13 drugs
acetylcysteineambroxolbromhexinedomiodoldornase alfaeprazinoneerdosteineletosteinemannitolmesnaneltenexinesobrerol show all 13 →

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Gastrointestinal ulcer contraindication 40845000
Gastrointestinal hemorrhage contraindication 74474003




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.15 acidic
pKa2 2.79 acidic
pKa3 9.51 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000170286 NUI
D06393 KEGG_DRUG
C0006992 UMLSCUI
CHEBI:16163 CHEBI
CAY PDB_CHEM_ID
CCS PDB_CHEM_ID
CHEMBL396416 ChEMBL_ID
DB04339 DRUGBANK_ID
193653 PUBCHEM_CID
2023 RXNORM
26469 MMSL
d05062 MMSL
003677 NDDF
395842001 SNOMEDCT_US
772923009 SNOMEDCT_US
D002233 MESH_DESCRIPTOR_UI
2884 INN_ID
740J2QX53R UNII

Pharmaceutical products:

None