pantethine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 3417 | 16816-67-4 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Platelet count decreased | 48.72 | 39.40 | 25 | 744 | 116097 | 63372156 |
FDA Adverse Event Reporting System (Male)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Pneumonia | 37.07 | 33.35 | 39 | 610 | 362588 | 34593694 |
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Platelet count decreased | 59.15 | 29.62 | 41 | 1584 | 194623 | 79548140 |
| Hepatic function abnormal | 50.02 | 29.62 | 26 | 1599 | 73081 | 79669682 |
| Ileus | 45.94 | 29.62 | 18 | 1607 | 26193 | 79716570 |
| Interstitial lung disease | 44.55 | 29.62 | 28 | 1597 | 112572 | 79630191 |
| Neutrophil count decreased | 41.31 | 29.62 | 25 | 1600 | 93934 | 79648829 |
| Pneumonia | 37.88 | 29.62 | 56 | 1569 | 660190 | 79082573 |
| Decreased appetite | 33.68 | 29.62 | 38 | 1587 | 342380 | 79400383 |
| Salivary hypersecretion | 33.01 | 29.62 | 12 | 1613 | 14212 | 79728551 |
| Pyrexia | 29.82 | 29.62 | 51 | 1574 | 678658 | 79064105 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A11HA32 | ALIMENTARY TRACT AND METABOLISM VITAMINS OTHER PLAIN VITAMIN PREPARATIONS Other plain vitamin preparations |
| CHEBI has role | CHEBI:23354 | coenzymes |
| CHEBI has role | CHEBI:50733 | Dietary Supplement |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 12.1 | acidic |
| pKa2 | 12.7 | acidic |
| pKa3 | 13.1 | acidic |
| pKa4 | 13.7 | acidic |
| pKa5 | 13.9 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D01234 | KEGG_DRUG |
| C0070034 | UMLSCUI |
| CHEBI:31959 | CHEBI |
| CHEMBL2104786 | ChEMBL_ID |
| DB11190 | DRUGBANK_ID |
| C005425 | MESH_SUPPLEMENTAL_RECORD_UI |
| 7K81IL792L | UNII |
| 452306 | PUBCHEM_CID |
| 32863 | RXNORM |
| 006957 | NDDF |
Pharmaceutical products:
None